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5-hydroxyflavone and 3-hydroxyflavone

5-hydroxyflavone has been researched along with 3-hydroxyflavone in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (16.67)18.2507
2000's6 (33.33)29.6817
2010's8 (44.44)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Constantinou, A; Mehta, R; Moon, R; Rao, K; Runyan, C; Vaughan, A1
Ares, JJ; Ems, BL; Kakodkar, SV; Kelm, GR; Kershaw, WC; Murray, PD; O'Brien, LM; Outt, PE; Randall, JL; Weisshaar, PS1
Albasini, A; Antolini, L; Bose, P; Costantino, L; Del Corso, A; Gamberini, MC; Iannone, A; Mura, U; Rastelli, G; Staffieri, M; Vinson, JA1
Brun, R; Lack, G; Perozzo, R; Rüedi, P; Scapozza, L; Tasdemir, D1
Akamatsu, M; Hosoda, A; Hotta, Y; Ishimoto, Y; Nishizaki, Y; Tamura, H; Yoshikawa, H1
Amić, D; Lucić, B1
Ataide Martins, JP; Borges de Melo, E; Castro Ferreira, MM; Friozi, MC; Marinho Jorge, TC1
Chan, CB; France, S; He, K; Huang, J; Jang, SW; Jia, Y; Liu, X; Luo, HR; Phun, LH; Pradoldej, S; Xiao, G; Ye, K1
Cahlikova, L; Chlebek, J; Havrankova, J; Hofman, J; Hostalkova, A; Lundova, T; Musilek, K; Novotna, E; Wsol, V; Zemanova, L1
Alunda, JM; Baptista, C; Behrens, B; Bifeld, E; Borsari, C; Clos, J; Cordeiro-da-Silva, A; Corral, MJ; Costantino, L; Costi, MP; Dello Iacono, L; Di Pisa, F; Eick, J; Ellinger, B; Ferrari, S; Gribbon, P; Gul, S; Henrich, S; Jiménez-Antón, MD; Keminer, O; Kohler, M; Kuzikov, M; Landi, G; Luciani, R; Mangani, S; Pellati, F; Poehner, I; Pozzi, C; Reinshagen, J; Santarem, N; Tait, A; Tejera Nevado, P; Torrado, J; Trande, M; Wade, RC; Witt, G; Wolf, M1
Dutour, R; Poirier, D1
Arora, S; Chaturvedi, A; Heuser, M; Joshi, G; Kumar, R; Patil, S1
Mosca, F; Pacifici, GM; Pietrabissa, A; Spisni, R; Vietri, M1
Cornard, JP; Lapouge, C1
Lewars, EG; March, RE1
Chao, PD; Hou, YC; Kuo, SC; Shia, CS; Tsai, SY1
Ash, S; De, SP; Misra, A; Pyne, S1
Ariese, F; Groen, J; Höfener, S; Kooijman, PC; Visscher, L1

Reviews

1 review(s) available for 5-hydroxyflavone and 3-hydroxyflavone

ArticleYear
Inhibitors of cytochrome P450 (CYP) 1B1.
    European journal of medicinal chemistry, 2017, Jul-28, Volume: 135

    Topics: Cytochrome P-450 CYP1B1; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Structure-Activity Relationship

2017

Other Studies

17 other study(ies) available for 5-hydroxyflavone and 3-hydroxyflavone

ArticleYear
Flavonoids as DNA topoisomerase antagonists and poisons: structure-activity relationships.
    Journal of natural products, 1995, Volume: 58, Issue:2

    Topics: DNA Damage; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; Electrophoresis, Agar Gel; Flavonoids; Hydroxylation; Plasmids; Protein Conformation; Structure-Activity Relationship; Topoisomerase I Inhibitors; Topoisomerase II Inhibitors

1995
Synthesis and biological evaluation of substituted flavones as gastroprotective agents.
    Journal of medicinal chemistry, 1995, Dec-08, Volume: 38, Issue:25

    Topics: Animals; Cytochrome P-450 CYP1A1; Cytochrome P-450 Enzyme System; Enzyme Induction; Ethanol; Flavonoids; Indomethacin; Magnetic Resonance Spectroscopy; Male; Mass Spectrometry; Microsomes, Liver; Oxidoreductases; Rats; Rats, Sprague-Dawley; Stomach Diseases; Structure-Activity Relationship

1995
1-Benzopyran-4-one antioxidants as aldose reductase inhibitors.
    Journal of medicinal chemistry, 1999, Jun-03, Volume: 42, Issue:11

    Topics: Aldehyde Reductase; Animals; Antioxidants; Benzopyrans; Cattle; Enzyme Inhibitors; Humans; Kidney; Lens, Crystalline; Lipoproteins, LDL; Lipoproteins, VLDL; Models, Molecular; Oxidation-Reduction; Structure-Activity Relationship

1999
Inhibition of Plasmodium falciparum fatty acid biosynthesis: evaluation of FabG, FabZ, and FabI as drug targets for flavonoids.
    Journal of medicinal chemistry, 2006, Jun-01, Volume: 49, Issue:11

    Topics: 3-Oxoacyl-(Acyl-Carrier-Protein) Reductase; Alcohol Oxidoreductases; Animals; Antimalarials; Catechin; Cells, Cultured; Chloroquine; Drug Resistance; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Fatty Acids; Flavones; Flavonoids; Humans; Hydro-Lyases; Kinetics; Luteolin; Phenols; Plasmodium falciparum; Polyphenols; Structure-Activity Relationship

2006
Effect of flavonoids on androgen and glucocorticoid receptors based on in vitro reporter gene assay.
    Bioorganic & medicinal chemistry letters, 2009, Aug-15, Volume: 19, Issue:16

    Topics: Androgen Receptor Antagonists; Androgens; Cell Line, Tumor; Flavonoids; Genes, Reporter; Humans; Receptors, Androgen; Receptors, Glucocorticoid; Structure-Activity Relationship

2009
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids.
    Bioorganic & medicinal chemistry, 2010, Jan-01, Volume: 18, Issue:1

    Topics: Flavonoids; Free Radical Scavengers; Models, Biological; Quantitative Structure-Activity Relationship; Quantum Theory; Software; Thermodynamics

2010
Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:10

    Topics: Algorithms; Antimutagenic Agents; Flavonoids; Fluorenes; Least-Squares Analysis; Models, Biological; Models, Molecular; Mutagens; Quantitative Structure-Activity Relationship; Salmonella typhimurium

2010
A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect.
    Journal of medicinal chemistry, 2010, Dec-09, Volume: 53, Issue:23

    Topics: Animals; Antidepressive Agents; Apoptosis; Flavones; Magnetic Resonance Spectroscopy; Male; Mice; Mice, Inbred C57BL; Neurogenesis; Spectrometry, Mass, Electrospray Ionization; Structure-Activity Relationship

2010
Flavones Inhibit the Activity of AKR1B10, a Promising Therapeutic Target for Cancer Treatment.
    Journal of natural products, 2015, Nov-25, Volume: 78, Issue:11

    Topics: Aldehyde Reductase; Aldo-Keto Reductases; Apigenin; Daunorubicin; Enzyme Inhibitors; Flavones; Flavonoids; HCT116 Cells; Humans; Luteolin; Molecular Conformation; Molecular Structure; Neoplasms

2015
Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs.
    Journal of medicinal chemistry, 2016, 08-25, Volume: 59, Issue:16

    Topics: Animals; Biological Products; Cell Line; Dose-Response Relationship, Drug; Flavonols; Humans; Macrophages; Mice; Mice, Inbred BALB C; Models, Molecular; Molecular Structure; Parasitic Sensitivity Tests; Structure-Activity Relationship; Trypanocidal Agents; Trypanosoma brucei brucei

2016
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2.
    Journal of medicinal chemistry, 2022, 01-27, Volume: 65, Issue:2

    Topics: Allosteric Regulation; Allosteric Site; Carrier Proteins; Chemistry, Pharmaceutical; Glycolysis; Humans; Membrane Proteins; Protein Kinase Inhibitors; Thyroid Hormone-Binding Proteins; Thyroid Hormones

2022
7-OH-flavone is sulfated in the human liver and duodenum, whereas 5-OH-flavone and 3-OH-flavone are potent inhibitors of SULT1A1 activity and 7-OH-flavone sulfation rate.
    Xenobiotica; the fate of foreign compounds in biological systems, 2002, Volume: 32, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Arylsulfotransferase; Duodenum; Enzyme Inhibitors; Female; Flavonoids; Humans; In Vitro Techniques; Kinetics; Liver; Male; Middle Aged; Substrate Specificity; Sulfates; Sulfotransferases

2002
Time dependent density functional theory study of electronic absorption properties of lead(II) complexes with a series of hydroxyflavones.
    The journal of physical chemistry. A, 2005, Aug-04, Volume: 109, Issue:30

    Topics: Algorithms; Electrons; Flavones; Flavonoids; Lead; Methanol; Models, Molecular; Molecular Structure; Organometallic Compounds; Quantum Theory; Solvents; Spectrum Analysis; Time Factors

2005
Fragmentation of 3-hydroxyflavone; a computational and mass spectrometric study.
    Rapid communications in mass spectrometry : RCM, 2007, Volume: 21, Issue:10

    Topics: Chemical Phenomena; Chemistry, Physical; Flavonoids; Models, Chemical; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry

2007
Metabolism and pharmacokinetics of 3,3',4',7-tetrahydroxyflavone (fisetin), 5-hydroxyflavone, and 7-hydroxyflavone and antihemolysis effects of fisetin and its serum metabolites.
    Journal of agricultural and food chemistry, 2009, Jan-14, Volume: 57, Issue:1

    Topics: Animals; Flavonoids; Flavonols; Glucuronides; Hemolysis; Male; Rats; Rats, Sprague-Dawley; Sulfates

2009
Excited state intramolecular proton transfer in 3-hydroxy flavone and 5-hydroxy flavone: a DFT based comparative study.
    Journal of molecular modeling, 2010, Volume: 16, Issue:5

    Topics: Electrons; Flavonoids; Light; Protons

2010
Fluorescence behavior of (selected) flavonols: a combined experimental and computational study.
    Physical chemistry chemical physics : PCCP, 2013, Aug-14, Volume: 15, Issue:30

    Topics: Apigenin; Flavonoids; Flavonols; Hydrogen-Ion Concentration; Kaempferols; Models, Molecular; Quantum Theory; Quercetin; Spectrophotometry

2013