Page last updated: 2024-09-03

5-hydroxycytosine and guanine

5-hydroxycytosine has been researched along with guanine in 16 studies

Compound Research Comparison

Studies (5-hydroxycytosine)	Trials (5-hydroxycytosine)	Recent Studies (post-2010) (5-hydroxycytosine)	Studies (guanine)	Trials (guanine)	Recent Studies (post-2010) (guanine)
41	1	10	16,278	822	4,809

Protein Interaction Comparison

Protein	Taxonomy	5-hydroxycytosine (IC50)	guanine (IC50)
Purine nucleoside phosphorylase	Homo sapiens (human)		5

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	8 (50.00)	18.2507
2000's	8 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Castro, GD; Castro, JA; Díaz Gómez, MI	1
Aruoma, OI; England, TG; Halliwell, B; Jenner, A	2
Arashidani, K; Iwamoto-Tanaka, N; Kasai, H; Muraoka, M	1
Dizdaroglu, M	1
Foksinski, M; Jaruga, P; Makarewicz, R; Olinski, R	1
Dizdaroglu, M; Sentürker, S	1
Halota, W; Jaruga, B; Jaruga, P; Olczak, A; Olinski, R	1
Bretonniere, Y; Cadet, J; Douki, T	1
Demple, B; Eide, L; Essigmann, JM; Gustad, EC; Henderson, PT; Luna, L; Seeberg, E	1
Vaisman, A; Woodgate, R	1
Bjørås, M; Luna, L; Morland, I; Rognes, T; Rolseth, V; Seeberg, E	1
Kathe, SD; Shen, GP; Wallace, SS	1
Dizdaroglu, M; Evans, MK; Jaruga, P; Lohani, A; Nyaga, SG; Trzeciak, AR	1
Hogue, BA; Kim, D; McNeill, DR; Wilson, DM; Wong, HK	1
Kawakami, A; Loakes, D; Morimitsu, T; Negishi, K; Okugawa, Y; Otsuka, C; Oyama, H; Sekine, D; Suzuki, T	1

Reviews

1 review(s) available for 5-hydroxycytosine and guanine

Article	Year
Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry. Free radical research, 1998, Volume: 29, Issue:6 Topics: Adenine; Animals; Artifacts; Base Pairing; Cattle; Cytosine; DNA; DNA Damage; DNA Repair; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Pentoxyl; Pyrimidines; Temperature; Thymus Gland	1998

Article

Year

Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry.

Free radical research, 1998, Volume: 29, Issue:6

Topics: Adenine; Animals; Artifacts; Base Pairing; Cattle; Cytosine; DNA; DNA Damage; DNA Repair; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Pentoxyl; Pyrimidines; Temperature; Thymus Gland

1998

Trials

1 trial(s) available for 5-hydroxycytosine and guanine

Article	Year
Oxidative DNA base damage in lymphocytes of HIV-infected drug users. Free radical research, 1999, Volume: 31, Issue:3 Topics: Adenine; Adolescent; Adult; Chromatin; Cytosine; DNA Damage; Guanine; HIV Infections; Humans; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Substance Abuse, Intravenous; Uracil	1999

Other Studies

14 other study(ies) available for 5-hydroxycytosine and guanine

Article	Year
DNA bases attack by reactive metabolites produced during carbon tetrachloride biotransformation and promotion of liver microsomal lipid peroxidation. Research communications in molecular pathology and pharmacology, 1997, Volume: 95, Issue:3 Topics: Animals; Biotransformation; Carbon Tetrachloride; Cytosine; DNA Adducts; DNA Damage; Guanine; Lipid Peroxidation; Male; Microsomes, Liver; Pentoxyl; Pyrimidines; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Thymine	1997
Measurement of oxidative DNA damage by gas chromatography-mass spectrometry: ethanethiol prevents artifactual generation of oxidized DNA bases. The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2) Topics: Adenine; Animals; Cattle; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Guanine Deaminase; Oxidation-Reduction; Pentoxyl; Sulfhydryl Compounds; Temperature	1998
Genotoxicity of ribo- and deoxyribonucleosides of 8-hydroxyguanine, 5-hydroxycytosine, and 2-hydroxyadenine: induction of SCE in human lymphocytes and mutagenicity in Salmonella typhimurium TA 100. Mutation research, 1998, Jul-17, Volume: 403, Issue:1-2 Topics: Cytosine; Deoxyribonucleosides; DNA Damage; Guanine; Humans; In Vitro Techniques; Lymphocytes; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Point Mutation; Ribonucleosides; Salmonella typhimurium; Sister Chromatid Exchange	1998
Determination of oxidative DNA base damage by gas chromatography-mass spectrometry. Effect of derivatization conditions on artifactual formation of certain base oxidation products. Free radical research, 1998, Volume: 29, Issue:4 Topics: Adenine; Animals; Artifacts; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Hydantoins; Hydrolysis; Nitrogen; Oxidation-Reduction; Pentoxyl; Purines; Pyrimidines; Temperature; Time Factors	1998
Oxidative DNA base damage in cancerous tissues of patients undergoing brachytherapy. Cancer letters, 1998, Oct-23, Volume: 132, Issue:1-2 Topics: Adenine; Brachytherapy; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Uracil; Uterine Cervical Neoplasms	1998
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or not? Free radical biology & medicine, 1999, Volume: 27, Issue:3-4 Topics: Adenine; Animals; Artifacts; Cattle; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleotides; Oxidation-Reduction; Pentoxyl; Trifluoroacetic Acid; Uracil	1999
Protection against radiation-induced degradation of DNA bases by polyamines. Radiation research, 2000, Volume: 153, Issue:1 Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine	2000
Human endonuclease III acts preferentially on DNA damage opposite guanine residues in DNA. Biochemistry, 2001, Jun-05, Volume: 40, Issue:22 Topics: Amino Acid Sequence; Base Pair Mismatch; Buffers; Carbon-Oxygen Lyases; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli Proteins; Guanine; Helix-Turn-Helix Motifs; Humans; Kinetics; Molecular Sequence Data; N-Glycosyl Hydrolases; Sequence Homology, Nucleic Acid; Substrate Specificity	2001
Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines. The EMBO journal, 2001, Nov-15, Volume: 20, Issue:22 Topics: Animals; Base Pair Mismatch; Base Pairing; Cytosine; DNA Damage; DNA Polymerase iota; DNA Primers; DNA-Directed DNA Polymerase; Guanine; Guanosine; Humans; Kinetics; Models, Chemical; Mutagenesis; Mutagenesis, Site-Directed; Oxygen; Time Factors; Uracil	2001
Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA. Nucleic acids research, 2002, Nov-15, Volume: 30, Issue:22 Topics: Amino Acid Sequence; Animals; Cell Line; Cytosine; DNA; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Gene Components; Guanine; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Nuclear Proteins; Oxidation-Reduction; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction; Spodoptera; Substrate Specificity; Tissue Distribution	2002
Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts. The Journal of biological chemistry, 2004, Apr-30, Volume: 279, Issue:18 Topics: Cell Extracts; Cell Nucleus; Cytosine; Deoxyribonucleosides; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Oxidation-Reduction; Pyrimidine Dimers; RNA Polymerase II; Templates, Genetic; Thymine; Transcription, Genetic	2004
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145. Carcinogenesis, 2004, Volume: 25, Issue:8 Topics: Adenine; Antioxidants; Blotting, Western; Catalase; Cell Division; Cell Line, Tumor; Cell Nucleus; Comet Assay; Cytosine; DNA; DNA Damage; Dose-Response Relationship, Drug; Electron Transport Complex IV; Gas Chromatography-Mass Spectrometry; Glutathione Peroxidase; Guanine; Humans; Kinetics; Male; Mitochondria; Oxygen; Polymorphism, Genetic; Prostatic Neoplasms; Superoxide Dismutase; Time Factors	2004
DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency. Biochemistry, 2005, Nov-01, Volume: 44, Issue:43 Topics: Adenine; Animals; Binding Sites; Cell Extracts; Cell Line; Cricetinae; Cytosine; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Guanine; Mutation; Ovary; Time Factors; Uracil; X-ray Repair Cross Complementing Protein 1	2005
Oligonucleotide transformation for the study of mutagenic specificities of DNA lesions in yeast. Nucleic acids symposium series (2004), 2007, Issue:51 Topics: Cytosine; DNA Damage; DNA Mutational Analysis; Guanine; Mutagenesis; Oligonucleotides; Saccharomyces cerevisiae; Transformation, Genetic	2007