Page last updated: 2024-09-03

5-hydroxycytosine and cytosine

5-hydroxycytosine has been researched along with cytosine in 39 studies

Compound Research Comparison

Studies
(5-hydroxycytosine)
Trials
(5-hydroxycytosine)
Recent Studies (post-2010)
(5-hydroxycytosine)
Studies
(cytosine)
Trials
(cytosine)
Recent Studies (post-2010) (cytosine)
4111011,1681423,214

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.56)18.7374
1990's15 (38.46)18.2507
2000's13 (33.33)29.6817
2010's8 (20.51)24.3611
2020's2 (5.13)2.80

Authors

AuthorsStudies
Kchromov, IS; Nigmatullin, TG; Sorotchkina, VV; Tikchonenko, TI1
Kow, YW; Lampman, GW; Purmal, AA; Wallace, SS1
Kow, YW; Purmal, AA; Wallace, SS1
Castro, GD; Castro, JA; Díaz Gómez, MI1
Aruoma, OI; England, TG; Halliwell, B; Jenner, A2
Arashidani, K; Iwamoto-Tanaka, N; Kasai, H; Muraoka, M1
Buckley, TJ; Dizdaroglu, M; Karahalil, B; Roldán-Arjona, T; Sentürker, S1
Cadet, J; D'Ham, C; Gasparutto, D; Jaquinod, M; Romieu, A1
Bjornsti, MA; Essigmann, JM; Fertala, J; Park, HJ; Pommier, Y; Pourquier, P; Ueng, LM; Wang, D1
Dizdaroglu, M1
Alseth, I; Bjørås, M; Eide, L; Pirovano, M; Rognes, T; Seeberg, E1
Foksinski, M; Jaruga, P; Makarewicz, R; Olinski, R1
Bohr, VA; Dianov, GL; Dizdaroglu, M; Hoehr, N; Lipinski, LJ; Mazur, SJ; Sentürker, S1
Dizdaroglu, M; Sentürker, S1
Halota, W; Jaruga, B; Jaruga, P; Olczak, A; Olinski, R1
Bretonniere, Y; Cadet, J; Douki, T1
Ferger, B; Halliwell, B; Jenner, A; Jenner, P; Rose, S1
Demple, B; Eide, L; Essigmann, JM; Gustad, EC; Henderson, PT; Luna, L; Seeberg, E1
Vaisman, A; Woodgate, R1
England, TG; Halliwell, B; Proteggente, AR; Rehman, A; Rice-Evans, CA1
Bjørås, M; Luna, L; Morland, I; Rognes, T; Rolseth, V; Seeberg, E1
Bjørås, M; Brunborg, G; Duale, N; Holme, JA; Larsen, CT; Olsen, AK; Seeberg, EC; Wiger, R1
Kathe, SD; Shen, GP; Wallace, SS1
Dizdaroglu, M; Evans, MK; Jaruga, P; Lohani, A; Nyaga, SG; Trzeciak, AR1
Aukrust, P; Bjørås, M; Frøland, SS; Johansen, RF; Luna, L; Müller, F; Seeberg, EC; Ueland, T1
Hogue, BA; Kim, D; McNeill, DR; Wilson, DM; Wong, HK1
Kawakami, A; Loakes, D; Morimitsu, T; Negishi, K; Okugawa, Y; Otsuka, C; Oyama, H; Sekine, D; Suzuki, T1
Bohr, VA; Bukowy, Z; Harrigan, JA; Ramsden, DA; Stevnsner, T; Tudek, B1
Giessing, AM; Hansen, T; Havelund, JF; Kirpekar, F; Rasmussen, A; Scott, LG1
Küpfer, PA; Leumann, CJ1
Averill, A; Doublié, S; Wallace, SS; Zahn, KE1
Hatanaka, Y; Inoue, H; Inoue, K; Kamimura, S; Kurotaki, YK; Ogonuki, N; Ogura, A; Oikawa, M1
Karolak, A; van der Vaart, A1
Ishiguro, K; Kimura, S; Sakai, Y; Suzuki, T1
Evéquoz, D; Fernandez, G; Katz, A; Küpfer, P; Leumann, C; Polacek, N; Willi, J1
Aguilera-Aguirre, L; Boldogh, I; Coskun, E; Dizdaroglu, M; Hazra, TK; Hosoki, K; Itazawa, T; Jaruga, P; Sur, S1
Cellai, F; Ceni, E; Galli, A; Giese, RW; Godschalk, R; Munnia, A; Peluso, M; Tarocchi, M; van Schooten, FJ1
Horiba, M; Inoue, T; Obika, S; Sakurai, Y; Yamaguchi, T; Yoshida, T1

Reviews

1 review(s) available for 5-hydroxycytosine and cytosine

ArticleYear
Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry.
    Free radical research, 1998, Volume: 29, Issue:6

    Topics: Adenine; Animals; Artifacts; Base Pairing; Cattle; Cytosine; DNA; DNA Damage; DNA Repair; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Pentoxyl; Pyrimidines; Temperature; Thymus Gland

1998

Trials

1 trial(s) available for 5-hydroxycytosine and cytosine

ArticleYear
Oxidative DNA base damage in lymphocytes of HIV-infected drug users.
    Free radical research, 1999, Volume: 31, Issue:3

    Topics: Adenine; Adolescent; Adult; Chromatin; Cytosine; DNA Damage; Guanine; HIV Infections; Humans; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Substance Abuse, Intravenous; Uracil

1999

Other Studies

37 other study(ies) available for 5-hydroxycytosine and cytosine

ArticleYear
A new nitrogen base 5-hydroxycytosine in phage N-17 DNA.
    FEBS letters, 1980, Aug-25, Volume: 118, Issue:1

    Topics: Bacteriophages; Base Composition; Chemical Phenomena; Chemistry; Cytosine; DNA, Viral; Mass Spectrometry; Shigella flexneri; Spectrophotometry, Ultraviolet

1980
The sequence context-dependent mispairing of 5-hydroxycytosine and 5-hydroxyuridine in vitro.
    Annals of the New York Academy of Sciences, 1994, Jul-29, Volume: 726

    Topics: Base Sequence; Cytosine; DNA Polymerase I; DNA Primers; DNA-Directed DNA Polymerase; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Uridine

1994
Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.
    Nucleic acids research, 1994, Jan-11, Volume: 22, Issue:1

    Topics: Base Sequence; Cytosine; DNA; DNA Polymerase I; Escherichia coli; Hydrogen Bonding; Molecular Sequence Data; Oligodeoxyribonucleotides; Oxidation-Reduction; Substrate Specificity; Templates, Genetic; Uracil

1994
DNA bases attack by reactive metabolites produced during carbon tetrachloride biotransformation and promotion of liver microsomal lipid peroxidation.
    Research communications in molecular pathology and pharmacology, 1997, Volume: 95, Issue:3

    Topics: Animals; Biotransformation; Carbon Tetrachloride; Cytosine; DNA Adducts; DNA Damage; Guanine; Lipid Peroxidation; Male; Microsomes, Liver; Pentoxyl; Pyrimidines; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Thymine

1997
Measurement of oxidative DNA damage by gas chromatography-mass spectrometry: ethanethiol prevents artifactual generation of oxidized DNA bases.
    The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2)

    Topics: Adenine; Animals; Cattle; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Guanine Deaminase; Oxidation-Reduction; Pentoxyl; Sulfhydryl Compounds; Temperature

1998
Genotoxicity of ribo- and deoxyribonucleosides of 8-hydroxyguanine, 5-hydroxycytosine, and 2-hydroxyadenine: induction of SCE in human lymphocytes and mutagenicity in Salmonella typhimurium TA 100.
    Mutation research, 1998, Jul-17, Volume: 403, Issue:1-2

    Topics: Cytosine; Deoxyribonucleosides; DNA Damage; Guanine; Humans; In Vitro Techniques; Lymphocytes; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Point Mutation; Ribonucleosides; Salmonella typhimurium; Sister Chromatid Exchange

1998
Determination of oxidative DNA base damage by gas chromatography-mass spectrometry. Effect of derivatization conditions on artifactual formation of certain base oxidation products.
    Free radical research, 1998, Volume: 29, Issue:4

    Topics: Adenine; Animals; Artifacts; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Hydantoins; Hydrolysis; Nitrogen; Oxidation-Reduction; Pentoxyl; Purines; Pyrimidines; Temperature; Time Factors

1998
Excision of products of oxidative DNA base damage by human NTH1 protein.
    Biochemistry, 1999, Jan-05, Volume: 38, Issue:1

    Topics: Barbiturates; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Repair; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Humans; Kinetics; Oxidation-Reduction; Substrate Specificity; Thymine; Uracil

1999
Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects.
    Biochemistry, 1999, Mar-16, Volume: 38, Issue:11

    Topics: Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA Repair; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Gas Chromatography-Mass Spectrometry; Kinetics; N-Glycosyl Hydrolases; Oligodeoxyribonucleotides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Thymine

1999
Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine.
    The Journal of biological chemistry, 1999, Mar-26, Volume: 274, Issue:13

    Topics: Camptothecin; Cytosine; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA-Binding Proteins; Guanosine; Humans; Kinetics; Molecular Structure; Mutation; Oligonucleotides; Oxidative Stress

1999
The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast.
    Molecular and cellular biology, 1999, Volume: 19, Issue:5

    Topics: Amino Acid Sequence; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Fungal; Gene Targeting; Genes, Fungal; Helix-Loop-Helix Motifs; Hydrogen Peroxide; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; N-Glycosyl Hydrolases; Oxidative Stress; Pyrimidines; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Substrate Specificity; Thymine; Ultraviolet Rays

1999
Oxidative DNA base damage in cancerous tissues of patients undergoing brachytherapy.
    Cancer letters, 1998, Oct-23, Volume: 132, Issue:1-2

    Topics: Adenine; Brachytherapy; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Uracil; Uterine Cervical Neoplasms

1998
Repair of oxidative DNA base lesions induced by fluorescent light is defective in xeroderma pigmentosum group A cells.
    Nucleic acids research, 1999, Aug-01, Volume: 27, Issue:15

    Topics: Cells, Cultured; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli Proteins; Fluorescence; Gamma Rays; Gas Chromatography-Mass Spectrometry; Humans; Lymphocytes; N-Glycosyl Hydrolases; Osmium Tetroxide; Oxidation-Reduction; Plasmids; Pyrimidines; Time Factors; Xeroderma Pigmentosum

1999
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or not?
    Free radical biology & medicine, 1999, Volume: 27, Issue:3-4

    Topics: Adenine; Animals; Artifacts; Cattle; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleotides; Oxidation-Reduction; Pentoxyl; Trifluoroacetic Acid; Uracil

1999
Protection against radiation-induced degradation of DNA bases by polyamines.
    Radiation research, 2000, Volume: 153, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine

2000
6-hydroxydopamine increases hydroxyl free radical production and DNA damage in rat striatum.
    Neuroreport, 2001, May-08, Volume: 12, Issue:6

    Topics: Adrenergic Agents; Animals; Corpus Striatum; Cytosine; DNA Damage; Gas Chromatography-Mass Spectrometry; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Male; Oxidopamine; Rats; Rats, Wistar

2001
Human endonuclease III acts preferentially on DNA damage opposite guanine residues in DNA.
    Biochemistry, 2001, Jun-05, Volume: 40, Issue:22

    Topics: Amino Acid Sequence; Base Pair Mismatch; Buffers; Carbon-Oxygen Lyases; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli Proteins; Guanine; Helix-Turn-Helix Motifs; Humans; Kinetics; Molecular Sequence Data; N-Glycosyl Hydrolases; Sequence Homology, Nucleic Acid; Substrate Specificity

2001
Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines.
    The EMBO journal, 2001, Nov-15, Volume: 20, Issue:22

    Topics: Animals; Base Pair Mismatch; Base Pairing; Cytosine; DNA Damage; DNA Polymerase iota; DNA Primers; DNA-Directed DNA Polymerase; Guanine; Guanosine; Humans; Kinetics; Models, Chemical; Mutagenesis; Mutagenesis, Site-Directed; Oxygen; Time Factors; Uracil

2001
Gender differences in steady-state levels of oxidative damage to DNA in healthy individuals.
    Free radical research, 2002, Volume: 36, Issue:2

    Topics: Adenine; Adult; Ascorbic Acid; Cytosine; DNA; DNA Damage; Female; Gas Chromatography-Mass Spectrometry; Health; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Pyrimidines; Sex Characteristics

2002
Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA.
    Nucleic acids research, 2002, Nov-15, Volume: 30, Issue:22

    Topics: Amino Acid Sequence; Animals; Cell Line; Cytosine; DNA; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Gene Components; Guanine; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Nuclear Proteins; Oxidation-Reduction; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction; Spodoptera; Substrate Specificity; Tissue Distribution

2002
Limited repair of 8-hydroxy-7,8-dihydroguanine residues in human testicular cells.
    Nucleic acids research, 2003, Feb-15, Volume: 31, Issue:4

    Topics: Adolescent; Adult; Aged; Animals; Cell Extracts; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA Repair; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli Proteins; Guanosine; Humans; Leukocytes, Mononuclear; Male; Middle Aged; N-Glycosyl Hydrolases; Rats; Rats, Wistar; Testis

2003
Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.
    The Journal of biological chemistry, 2004, Apr-30, Volume: 279, Issue:18

    Topics: Cell Extracts; Cell Nucleus; Cytosine; Deoxyribonucleosides; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Oxidation-Reduction; Pyrimidine Dimers; RNA Polymerase II; Templates, Genetic; Thymine; Transcription, Genetic

2004
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.
    Carcinogenesis, 2004, Volume: 25, Issue:8

    Topics: Adenine; Antioxidants; Blotting, Western; Catalase; Cell Division; Cell Line, Tumor; Cell Nucleus; Comet Assay; Cytosine; DNA; DNA Damage; Dose-Response Relationship, Drug; Electron Transport Complex IV; Gas Chromatography-Mass Spectrometry; Glutathione Peroxidase; Guanine; Humans; Kinetics; Male; Mitochondria; Oxygen; Polymorphism, Genetic; Prostatic Neoplasms; Superoxide Dismutase; Time Factors

2004
Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients.
    Blood, 2005, Jun-15, Volume: 105, Issue:12

    Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Nucleus; Cytosine; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Female; Guanosine; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Oxidative Stress; Oxygen; T-Lymphocytes

2005
DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency.
    Biochemistry, 2005, Nov-01, Volume: 44, Issue:43

    Topics: Adenine; Animals; Binding Sites; Cell Extracts; Cell Line; Cricetinae; Cytosine; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Guanine; Mutation; Ovary; Time Factors; Uracil; X-ray Repair Cross Complementing Protein 1

2005
Oligonucleotide transformation for the study of mutagenic specificities of DNA lesions in yeast.
    Nucleic acids symposium series (2004), 2007, Issue:51

    Topics: Cytosine; DNA Damage; DNA Mutational Analysis; Guanine; Mutagenesis; Oligonucleotides; Saccharomyces cerevisiae; Transformation, Genetic

2007
WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand.
    Nucleic acids research, 2008, Volume: 36, Issue:15

    Topics: Antigens, Nuclear; Cytosine; DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Binding Proteins; Exodeoxyribonucleases; Humans; Ku Autoantigen; Oxidative Stress; RecQ Helicases; Uracil; Werner Syndrome Helicase

2008
Identification of 5-hydroxycytidine at position 2501 concludes characterization of modified nucleotides in E. coli 23S rRNA.
    Journal of molecular biology, 2011, Aug-19, Volume: 411, Issue:3

    Topics: Chromatography, Liquid; Cytosine; Deinococcus; Escherichia coli; Mass Spectrometry; Models, Chemical; Nucleic Acid Conformation; Nucleotides; Polymorphism, Single Nucleotide; Ribosomes; RNA, Bacterial; RNA, Ribosomal, 23S

2011
Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine.
    Nucleic acids research, 2011, Volume: 39, Issue:21

    Topics: Base Pairing; Cytosine; Nucleic Acid Denaturation; Oligoribonucleotides; Organophosphorus Compounds; Oxidation-Reduction; RNA-Directed DNA Polymerase

2011
The miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site.
    Biochemistry, 2011, Nov-29, Volume: 50, Issue:47

    Topics: Bacteriophages; Base Pairing; Catalytic Domain; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Templates, Genetic; Viral Proteins

2011
Impaired active DNA demethylation in zygotes generated by round spermatid injection.
    Human reproduction (Oxford, England), 2015, Volume: 30, Issue:5

    Topics: 5-Methylcytosine; Animals; Cell Nucleus; Chorionic Gonadotropin; Cytosine; DNA Methylation; Embryo Transfer; Female; Germ Cells; Histones; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Microscopy, Fluorescence; Oocytes; Pregnancy; Pregnancy, Animal; Sperm Injections, Intracytoplasmic; Spermatids; Zygote

2015
Molecular Dynamics Simulations of 5-Hydroxycytosine Damaged DNA.
    The journal of physical chemistry. B, 2016, Jan-14, Volume: 120, Issue:1

    Topics: Cytosine; DNA; DNA Damage; Molecular Dynamics Simulation; Molecular Structure; Oxidation-Reduction

2016
Biogenesis and iron-dependency of ribosomal RNA hydroxylation.
    Nucleic acids research, 2017, Dec-15, Volume: 45, Issue:22

    Topics: Base Sequence; Biosynthetic Pathways; Cyclohexanecarboxylic Acids; Cyclohexenes; Cytosine; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydroxylation; Iron; Mutation; Ribosomes; RNA, Bacterial; RNA, Ribosomal; RNA, Ribosomal, 23S

2017
Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center.
    Nucleic acids research, 2018, 02-28, Volume: 46, Issue:4

    Topics: Adenosine; Cytosine; Mutagenesis; Oxidative Stress; Peptidyl Transferases; Protein Biosynthesis; Ribosomes; RNA, Ribosomal; RNA, Transfer; Uridine

2018
Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2018, Volume: 48, Issue:12

    Topics: Allergens; Animals; Biomarkers; Cats; Chromatography, Gas; Cytosine; Disease Models, Animal; DNA Damage; Hypersensitivity; Immunity, Innate; Immunoglobulin E; Lung; Mice; Mice, Knockout; Myeloid Differentiation Factor 88; Oxidative Stress; Pneumonia; Reactive Oxygen Species; Tandem Mass Spectrometry

2018
Ligation-Mediated Polymerase Chain Reaction Detection of 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and 5-Hydroxycytosine at the Codon 176 of the p53 Gene of Hepatitis C-Associated Hepatocellular Carcinoma Patients.
    International journal of molecular sciences, 2020, Sep-15, Volume: 21, Issue:18

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Carcinoma, Hepatocellular; Cell Line, Tumor; Codon; Cytosine; DNA Adducts; Genes, p53; Hep G2 Cells; Hepacivirus; Hepatitis C; Humans; Lipid Peroxidation; Liver Neoplasms; Polymerase Chain Reaction; Reactive Oxygen Species

2020
Synthesis and Properties of Nucleobase-Sugar Dual Modified Nucleic Acids: 2
    The Journal of organic chemistry, 2023, 01-06, Volume: 88, Issue:1

    Topics: Chemical and Drug Induced Liver Injury; Cytosine; Humans; Nucleic Acids; Oligonucleotides; Oligonucleotides, Antisense; RNA; Sugar Acids; Sugars

2023