5-hydroxycytosine has been researched along with cytosine in 39 studies
Studies (5-hydroxycytosine) | Trials (5-hydroxycytosine) | Recent Studies (post-2010) (5-hydroxycytosine) | Studies (cytosine) | Trials (cytosine) | Recent Studies (post-2010) (cytosine) |
---|---|---|---|---|---|
41 | 1 | 10 | 11,168 | 142 | 3,214 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (2.56) | 18.7374 |
1990's | 15 (38.46) | 18.2507 |
2000's | 13 (33.33) | 29.6817 |
2010's | 8 (20.51) | 24.3611 |
2020's | 2 (5.13) | 2.80 |
Authors | Studies |
---|---|
Kchromov, IS; Nigmatullin, TG; Sorotchkina, VV; Tikchonenko, TI | 1 |
Kow, YW; Lampman, GW; Purmal, AA; Wallace, SS | 1 |
Kow, YW; Purmal, AA; Wallace, SS | 1 |
Castro, GD; Castro, JA; Díaz Gómez, MI | 1 |
Aruoma, OI; England, TG; Halliwell, B; Jenner, A | 2 |
Arashidani, K; Iwamoto-Tanaka, N; Kasai, H; Muraoka, M | 1 |
Buckley, TJ; Dizdaroglu, M; Karahalil, B; Roldán-Arjona, T; Sentürker, S | 1 |
Cadet, J; D'Ham, C; Gasparutto, D; Jaquinod, M; Romieu, A | 1 |
Bjornsti, MA; Essigmann, JM; Fertala, J; Park, HJ; Pommier, Y; Pourquier, P; Ueng, LM; Wang, D | 1 |
Dizdaroglu, M | 1 |
Alseth, I; Bjørås, M; Eide, L; Pirovano, M; Rognes, T; Seeberg, E | 1 |
Foksinski, M; Jaruga, P; Makarewicz, R; Olinski, R | 1 |
Bohr, VA; Dianov, GL; Dizdaroglu, M; Hoehr, N; Lipinski, LJ; Mazur, SJ; Sentürker, S | 1 |
Dizdaroglu, M; Sentürker, S | 1 |
Halota, W; Jaruga, B; Jaruga, P; Olczak, A; Olinski, R | 1 |
Bretonniere, Y; Cadet, J; Douki, T | 1 |
Ferger, B; Halliwell, B; Jenner, A; Jenner, P; Rose, S | 1 |
Demple, B; Eide, L; Essigmann, JM; Gustad, EC; Henderson, PT; Luna, L; Seeberg, E | 1 |
Vaisman, A; Woodgate, R | 1 |
England, TG; Halliwell, B; Proteggente, AR; Rehman, A; Rice-Evans, CA | 1 |
Bjørås, M; Luna, L; Morland, I; Rognes, T; Rolseth, V; Seeberg, E | 1 |
Bjørås, M; Brunborg, G; Duale, N; Holme, JA; Larsen, CT; Olsen, AK; Seeberg, EC; Wiger, R | 1 |
Kathe, SD; Shen, GP; Wallace, SS | 1 |
Dizdaroglu, M; Evans, MK; Jaruga, P; Lohani, A; Nyaga, SG; Trzeciak, AR | 1 |
Aukrust, P; Bjørås, M; Frøland, SS; Johansen, RF; Luna, L; Müller, F; Seeberg, EC; Ueland, T | 1 |
Hogue, BA; Kim, D; McNeill, DR; Wilson, DM; Wong, HK | 1 |
Kawakami, A; Loakes, D; Morimitsu, T; Negishi, K; Okugawa, Y; Otsuka, C; Oyama, H; Sekine, D; Suzuki, T | 1 |
Bohr, VA; Bukowy, Z; Harrigan, JA; Ramsden, DA; Stevnsner, T; Tudek, B | 1 |
Giessing, AM; Hansen, T; Havelund, JF; Kirpekar, F; Rasmussen, A; Scott, LG | 1 |
Küpfer, PA; Leumann, CJ | 1 |
Averill, A; Doublié, S; Wallace, SS; Zahn, KE | 1 |
Hatanaka, Y; Inoue, H; Inoue, K; Kamimura, S; Kurotaki, YK; Ogonuki, N; Ogura, A; Oikawa, M | 1 |
Karolak, A; van der Vaart, A | 1 |
Ishiguro, K; Kimura, S; Sakai, Y; Suzuki, T | 1 |
Evéquoz, D; Fernandez, G; Katz, A; Küpfer, P; Leumann, C; Polacek, N; Willi, J | 1 |
Aguilera-Aguirre, L; Boldogh, I; Coskun, E; Dizdaroglu, M; Hazra, TK; Hosoki, K; Itazawa, T; Jaruga, P; Sur, S | 1 |
Cellai, F; Ceni, E; Galli, A; Giese, RW; Godschalk, R; Munnia, A; Peluso, M; Tarocchi, M; van Schooten, FJ | 1 |
Horiba, M; Inoue, T; Obika, S; Sakurai, Y; Yamaguchi, T; Yoshida, T | 1 |
1 review(s) available for 5-hydroxycytosine and cytosine
Article | Year |
---|---|
Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry.
Topics: Adenine; Animals; Artifacts; Base Pairing; Cattle; Cytosine; DNA; DNA Damage; DNA Repair; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Pentoxyl; Pyrimidines; Temperature; Thymus Gland | 1998 |
1 trial(s) available for 5-hydroxycytosine and cytosine
Article | Year |
---|---|
Oxidative DNA base damage in lymphocytes of HIV-infected drug users.
Topics: Adenine; Adolescent; Adult; Chromatin; Cytosine; DNA Damage; Guanine; HIV Infections; Humans; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Substance Abuse, Intravenous; Uracil | 1999 |
37 other study(ies) available for 5-hydroxycytosine and cytosine
Article | Year |
---|---|
A new nitrogen base 5-hydroxycytosine in phage N-17 DNA.
Topics: Bacteriophages; Base Composition; Chemical Phenomena; Chemistry; Cytosine; DNA, Viral; Mass Spectrometry; Shigella flexneri; Spectrophotometry, Ultraviolet | 1980 |
The sequence context-dependent mispairing of 5-hydroxycytosine and 5-hydroxyuridine in vitro.
Topics: Base Sequence; Cytosine; DNA Polymerase I; DNA Primers; DNA-Directed DNA Polymerase; Molecular Sequence Data; Nucleic Acid Heteroduplexes; Uridine | 1994 |
Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.
Topics: Base Sequence; Cytosine; DNA; DNA Polymerase I; Escherichia coli; Hydrogen Bonding; Molecular Sequence Data; Oligodeoxyribonucleotides; Oxidation-Reduction; Substrate Specificity; Templates, Genetic; Uracil | 1994 |
DNA bases attack by reactive metabolites produced during carbon tetrachloride biotransformation and promotion of liver microsomal lipid peroxidation.
Topics: Animals; Biotransformation; Carbon Tetrachloride; Cytosine; DNA Adducts; DNA Damage; Guanine; Lipid Peroxidation; Male; Microsomes, Liver; Pentoxyl; Pyrimidines; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Thymine | 1997 |
Measurement of oxidative DNA damage by gas chromatography-mass spectrometry: ethanethiol prevents artifactual generation of oxidized DNA bases.
Topics: Adenine; Animals; Cattle; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Guanine Deaminase; Oxidation-Reduction; Pentoxyl; Sulfhydryl Compounds; Temperature | 1998 |
Genotoxicity of ribo- and deoxyribonucleosides of 8-hydroxyguanine, 5-hydroxycytosine, and 2-hydroxyadenine: induction of SCE in human lymphocytes and mutagenicity in Salmonella typhimurium TA 100.
Topics: Cytosine; Deoxyribonucleosides; DNA Damage; Guanine; Humans; In Vitro Techniques; Lymphocytes; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Point Mutation; Ribonucleosides; Salmonella typhimurium; Sister Chromatid Exchange | 1998 |
Determination of oxidative DNA base damage by gas chromatography-mass spectrometry. Effect of derivatization conditions on artifactual formation of certain base oxidation products.
Topics: Adenine; Animals; Artifacts; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Hydantoins; Hydrolysis; Nitrogen; Oxidation-Reduction; Pentoxyl; Purines; Pyrimidines; Temperature; Time Factors | 1998 |
Excision of products of oxidative DNA base damage by human NTH1 protein.
Topics: Barbiturates; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Repair; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Humans; Kinetics; Oxidation-Reduction; Substrate Specificity; Thymine; Uracil | 1999 |
Excision of 5,6-dihydroxy-5,6-dihydrothymine, 5,6-dihydrothymine, and 5-hydroxycytosine from defined sequence oligonucleotides by Escherichia coli endonuclease III and Fpg proteins: kinetic and mechanistic aspects.
Topics: Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA Repair; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Gas Chromatography-Mass Spectrometry; Kinetics; N-Glycosyl Hydrolases; Oligodeoxyribonucleotides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Thymine | 1999 |
Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine.
Topics: Camptothecin; Cytosine; DNA; DNA Damage; DNA Topoisomerases, Type I; DNA-Binding Proteins; Guanosine; Humans; Kinetics; Molecular Structure; Mutation; Oligonucleotides; Oxidative Stress | 1999 |
The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast.
Topics: Amino Acid Sequence; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Fungal; Gene Targeting; Genes, Fungal; Helix-Loop-Helix Motifs; Hydrogen Peroxide; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; N-Glycosyl Hydrolases; Oxidative Stress; Pyrimidines; RNA, Messenger; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Sequence Alignment; Substrate Specificity; Thymine; Ultraviolet Rays | 1999 |
Oxidative DNA base damage in cancerous tissues of patients undergoing brachytherapy.
Topics: Adenine; Brachytherapy; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Uracil; Uterine Cervical Neoplasms | 1998 |
Repair of oxidative DNA base lesions induced by fluorescent light is defective in xeroderma pigmentosum group A cells.
Topics: Cells, Cultured; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli Proteins; Fluorescence; Gamma Rays; Gas Chromatography-Mass Spectrometry; Humans; Lymphocytes; N-Glycosyl Hydrolases; Osmium Tetroxide; Oxidation-Reduction; Plasmids; Pyrimidines; Time Factors; Xeroderma Pigmentosum | 1999 |
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or not?
Topics: Adenine; Animals; Artifacts; Cattle; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleotides; Oxidation-Reduction; Pentoxyl; Trifluoroacetic Acid; Uracil | 1999 |
Protection against radiation-induced degradation of DNA bases by polyamines.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine | 2000 |
6-hydroxydopamine increases hydroxyl free radical production and DNA damage in rat striatum.
Topics: Adrenergic Agents; Animals; Corpus Striatum; Cytosine; DNA Damage; Gas Chromatography-Mass Spectrometry; Hydroxybenzoates; Hydroxyl Radical; Hypoxanthine; Male; Oxidopamine; Rats; Rats, Wistar | 2001 |
Human endonuclease III acts preferentially on DNA damage opposite guanine residues in DNA.
Topics: Amino Acid Sequence; Base Pair Mismatch; Buffers; Carbon-Oxygen Lyases; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli Proteins; Guanine; Helix-Turn-Helix Motifs; Humans; Kinetics; Molecular Sequence Data; N-Glycosyl Hydrolases; Sequence Homology, Nucleic Acid; Substrate Specificity | 2001 |
Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosines.
Topics: Animals; Base Pair Mismatch; Base Pairing; Cytosine; DNA Damage; DNA Polymerase iota; DNA Primers; DNA-Directed DNA Polymerase; Guanine; Guanosine; Humans; Kinetics; Models, Chemical; Mutagenesis; Mutagenesis, Site-Directed; Oxygen; Time Factors; Uracil | 2001 |
Gender differences in steady-state levels of oxidative damage to DNA in healthy individuals.
Topics: Adenine; Adult; Ascorbic Acid; Cytosine; DNA; DNA Damage; Female; Gas Chromatography-Mass Spectrometry; Health; Humans; Male; Middle Aged; Oxidation-Reduction; Oxidative Stress; Pyrimidines; Sex Characteristics | 2002 |
Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA.
Topics: Amino Acid Sequence; Animals; Cell Line; Cytosine; DNA; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Gene Components; Guanine; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Nuclear Proteins; Oxidation-Reduction; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction; Spodoptera; Substrate Specificity; Tissue Distribution | 2002 |
Limited repair of 8-hydroxy-7,8-dihydroguanine residues in human testicular cells.
Topics: Adolescent; Adult; Aged; Animals; Cell Extracts; Cytosine; Deoxyribonuclease (Pyrimidine Dimer); DNA Repair; DNA-Formamidopyrimidine Glycosylase; Endodeoxyribonucleases; Escherichia coli Proteins; Guanosine; Humans; Leukocytes, Mononuclear; Male; Middle Aged; N-Glycosyl Hydrolases; Rats; Rats, Wistar; Testis | 2003 |
Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.
Topics: Cell Extracts; Cell Nucleus; Cytosine; Deoxyribonucleosides; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Oxidation-Reduction; Pyrimidine Dimers; RNA Polymerase II; Templates, Genetic; Thymine; Transcription, Genetic | 2004 |
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.
Topics: Adenine; Antioxidants; Blotting, Western; Catalase; Cell Division; Cell Line, Tumor; Cell Nucleus; Comet Assay; Cytosine; DNA; DNA Damage; Dose-Response Relationship, Drug; Electron Transport Complex IV; Gas Chromatography-Mass Spectrometry; Glutathione Peroxidase; Guanine; Humans; Kinetics; Male; Mitochondria; Oxygen; Polymorphism, Genetic; Prostatic Neoplasms; Superoxide Dismutase; Time Factors | 2004 |
Impaired base excision repair and accumulation of oxidative base lesions in CD4+ T cells of HIV-infected patients.
Topics: Adult; Anti-Retroviral Agents; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Nucleus; Cytosine; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Female; Guanosine; HIV; HIV Infections; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Oxidative Stress; Oxygen; T-Lymphocytes | 2005 |
DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency.
Topics: Adenine; Animals; Binding Sites; Cell Extracts; Cell Line; Cricetinae; Cytosine; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Guanine; Mutation; Ovary; Time Factors; Uracil; X-ray Repair Cross Complementing Protein 1 | 2005 |
Oligonucleotide transformation for the study of mutagenic specificities of DNA lesions in yeast.
Topics: Cytosine; DNA Damage; DNA Mutational Analysis; Guanine; Mutagenesis; Oligonucleotides; Saccharomyces cerevisiae; Transformation, Genetic | 2007 |
WRN Exonuclease activity is blocked by specific oxidatively induced base lesions positioned in either DNA strand.
Topics: Antigens, Nuclear; Cytosine; DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Binding Proteins; Exodeoxyribonucleases; Humans; Ku Autoantigen; Oxidative Stress; RecQ Helicases; Uracil; Werner Syndrome Helicase | 2008 |
Identification of 5-hydroxycytidine at position 2501 concludes characterization of modified nucleotides in E. coli 23S rRNA.
Topics: Chromatography, Liquid; Cytosine; Deinococcus; Escherichia coli; Mass Spectrometry; Models, Chemical; Nucleic Acid Conformation; Nucleotides; Polymorphism, Single Nucleotide; Ribosomes; RNA, Bacterial; RNA, Ribosomal, 23S | 2011 |
Synthesis, base pairing properties and trans-lesion synthesis by reverse transcriptases of oligoribonucleotides containing the oxidatively damaged base 5-hydroxycytidine.
Topics: Base Pairing; Cytosine; Nucleic Acid Denaturation; Oligoribonucleotides; Organophosphorus Compounds; Oxidation-Reduction; RNA-Directed DNA Polymerase | 2011 |
The miscoding potential of 5-hydroxycytosine arises due to template instability in the replicative polymerase active site.
Topics: Bacteriophages; Base Pairing; Catalytic Domain; Cytosine; DNA Replication; DNA-Directed DNA Polymerase; Templates, Genetic; Viral Proteins | 2011 |
Impaired active DNA demethylation in zygotes generated by round spermatid injection.
Topics: 5-Methylcytosine; Animals; Cell Nucleus; Chorionic Gonadotropin; Cytosine; DNA Methylation; Embryo Transfer; Female; Germ Cells; Histones; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Microscopy, Fluorescence; Oocytes; Pregnancy; Pregnancy, Animal; Sperm Injections, Intracytoplasmic; Spermatids; Zygote | 2015 |
Molecular Dynamics Simulations of 5-Hydroxycytosine Damaged DNA.
Topics: Cytosine; DNA; DNA Damage; Molecular Dynamics Simulation; Molecular Structure; Oxidation-Reduction | 2016 |
Biogenesis and iron-dependency of ribosomal RNA hydroxylation.
Topics: Base Sequence; Biosynthetic Pathways; Cyclohexanecarboxylic Acids; Cyclohexenes; Cytosine; Escherichia coli; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Hydroxylation; Iron; Mutation; Ribosomes; RNA, Bacterial; RNA, Ribosomal; RNA, Ribosomal, 23S | 2017 |
Oxidative stress damages rRNA inside the ribosome and differentially affects the catalytic center.
Topics: Adenosine; Cytosine; Mutagenesis; Oxidative Stress; Peptidyl Transferases; Protein Biosynthesis; Ribosomes; RNA, Ribosomal; RNA, Transfer; Uridine | 2018 |
Excision release of 5?hydroxycytosine oxidatively induced DNA base lesions from the lung genome by cat dander extract challenge stimulates allergic airway inflammation.
Topics: Allergens; Animals; Biomarkers; Cats; Chromatography, Gas; Cytosine; Disease Models, Animal; DNA Damage; Hypersensitivity; Immunity, Innate; Immunoglobulin E; Lung; Mice; Mice, Knockout; Myeloid Differentiation Factor 88; Oxidative Stress; Pneumonia; Reactive Oxygen Species; Tandem Mass Spectrometry | 2018 |
Ligation-Mediated Polymerase Chain Reaction Detection of 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and 5-Hydroxycytosine at the Codon 176 of the p53 Gene of Hepatitis C-Associated Hepatocellular Carcinoma Patients.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Carcinoma, Hepatocellular; Cell Line, Tumor; Codon; Cytosine; DNA Adducts; Genes, p53; Hep G2 Cells; Hepacivirus; Hepatitis C; Humans; Lipid Peroxidation; Liver Neoplasms; Polymerase Chain Reaction; Reactive Oxygen Species | 2020 |
Synthesis and Properties of Nucleobase-Sugar Dual Modified Nucleic Acids: 2
Topics: Chemical and Drug Induced Liver Injury; Cytosine; Humans; Nucleic Acids; Oligonucleotides; Oligonucleotides, Antisense; RNA; Sugar Acids; Sugars | 2023 |