Page last updated: 2024-09-03

5-hydroxycytosine and 8-hydroxyguanine

5-hydroxycytosine has been researched along with 8-hydroxyguanine in 12 studies

Compound Research Comparison

Studies
(5-hydroxycytosine)
Trials
(5-hydroxycytosine)
Recent Studies (post-2010)
(5-hydroxycytosine)
Studies
(8-hydroxyguanine)
Trials
(8-hydroxyguanine)
Recent Studies (post-2010) (8-hydroxyguanine)
411101,28914481

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (58.33)18.2507
2000's5 (41.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aruoma, OI; England, TG; Halliwell, B; Jenner, A2
Arashidani, K; Iwamoto-Tanaka, N; Kasai, H; Muraoka, M1
Dizdaroglu, M1
Foksinski, M; Jaruga, P; Makarewicz, R; Olinski, R1
Dizdaroglu, M; Sentürker, S1
Halota, W; Jaruga, B; Jaruga, P; Olczak, A; Olinski, R1
Bretonniere, Y; Cadet, J; Douki, T1
Bjørås, M; Luna, L; Morland, I; Rognes, T; Rolseth, V; Seeberg, E1
Kathe, SD; Shen, GP; Wallace, SS1
Dizdaroglu, M; Evans, MK; Jaruga, P; Lohani, A; Nyaga, SG; Trzeciak, AR1
Hogue, BA; Kim, D; McNeill, DR; Wilson, DM; Wong, HK1

Reviews

1 review(s) available for 5-hydroxycytosine and 8-hydroxyguanine

ArticleYear
Facts about the artifacts in the measurement of oxidative DNA base damage by gas chromatography-mass spectrometry.
    Free radical research, 1998, Volume: 29, Issue:6

    Topics: Adenine; Animals; Artifacts; Base Pairing; Cattle; Cytosine; DNA; DNA Damage; DNA Repair; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Oxidative Stress; Pentoxyl; Pyrimidines; Temperature; Thymus Gland

1998

Trials

1 trial(s) available for 5-hydroxycytosine and 8-hydroxyguanine

ArticleYear
Oxidative DNA base damage in lymphocytes of HIV-infected drug users.
    Free radical research, 1999, Volume: 31, Issue:3

    Topics: Adenine; Adolescent; Adult; Chromatin; Cytosine; DNA Damage; Guanine; HIV Infections; Humans; Lymphocytes; Male; Oxidation-Reduction; Oxidative Stress; Substance Abuse, Intravenous; Uracil

1999

Other Studies

10 other study(ies) available for 5-hydroxycytosine and 8-hydroxyguanine

ArticleYear
Measurement of oxidative DNA damage by gas chromatography-mass spectrometry: ethanethiol prevents artifactual generation of oxidized DNA bases.
    The Biochemical journal, 1998, Apr-15, Volume: 331 ( Pt 2)

    Topics: Adenine; Animals; Cattle; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Guanine Deaminase; Oxidation-Reduction; Pentoxyl; Sulfhydryl Compounds; Temperature

1998
Genotoxicity of ribo- and deoxyribonucleosides of 8-hydroxyguanine, 5-hydroxycytosine, and 2-hydroxyadenine: induction of SCE in human lymphocytes and mutagenicity in Salmonella typhimurium TA 100.
    Mutation research, 1998, Jul-17, Volume: 403, Issue:1-2

    Topics: Cytosine; Deoxyribonucleosides; DNA Damage; Guanine; Humans; In Vitro Techniques; Lymphocytes; Mutagenicity Tests; Mutagens; Oxidation-Reduction; Point Mutation; Ribonucleosides; Salmonella typhimurium; Sister Chromatid Exchange

1998
Determination of oxidative DNA base damage by gas chromatography-mass spectrometry. Effect of derivatization conditions on artifactual formation of certain base oxidation products.
    Free radical research, 1998, Volume: 29, Issue:4

    Topics: Adenine; Animals; Artifacts; Cytosine; DNA; DNA Damage; Gas Chromatography-Mass Spectrometry; Guanine; Hydantoins; Hydrolysis; Nitrogen; Oxidation-Reduction; Pentoxyl; Purines; Pyrimidines; Temperature; Time Factors

1998
Oxidative DNA base damage in cancerous tissues of patients undergoing brachytherapy.
    Cancer letters, 1998, Oct-23, Volume: 132, Issue:1-2

    Topics: Adenine; Brachytherapy; Cytosine; DNA Damage; DNA, Neoplasm; Female; Gas Chromatography-Mass Spectrometry; Guanine; Humans; Oxidation-Reduction; Pyrimidines; Uracil; Uterine Cervical Neoplasms

1998
The effect of experimental conditions on the levels of oxidatively modified bases in DNA as measured by gas chromatography-mass spectrometry: how many modified bases are involved? Prepurification or not?
    Free radical biology & medicine, 1999, Volume: 27, Issue:3-4

    Topics: Adenine; Animals; Artifacts; Cattle; Cytosine; DNA; Gas Chromatography-Mass Spectrometry; Guanine; Hydrolysis; Nucleotides; Oxidation-Reduction; Pentoxyl; Trifluoroacetic Acid; Uracil

1999
Protection against radiation-induced degradation of DNA bases by polyamines.
    Radiation research, 2000, Volume: 153, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Amidines; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Dimethyl Sulfoxide; DNA; DNA Damage; Dose-Response Relationship, Drug; Gamma Rays; Gas Chromatography-Mass Spectrometry; Guanine; Hydroxyl Radical; Oxidation-Reduction; Polyamines; Purines; Putrescine; Pyrimidines; Radiation-Protective Agents; Solutions; Spermidine; Spermine

2000
Human DNA glycosylases of the bacterial Fpg/MutM superfamily: an alternative pathway for the repair of 8-oxoguanine and other oxidation products in DNA.
    Nucleic acids research, 2002, Nov-15, Volume: 30, Issue:22

    Topics: Amino Acid Sequence; Animals; Cell Line; Cytosine; DNA; DNA Glycosylases; DNA Repair; DNA-Formamidopyrimidine Glycosylase; Escherichia coli; Escherichia coli Proteins; Gene Components; Guanine; HeLa Cells; Humans; Molecular Sequence Data; N-Glycosyl Hydrolases; Nuclear Proteins; Oxidation-Reduction; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction; Spodoptera; Substrate Specificity; Tissue Distribution

2002
Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.
    The Journal of biological chemistry, 2004, Apr-30, Volume: 279, Issue:18

    Topics: Cell Extracts; Cell Nucleus; Cytosine; Deoxyribonucleosides; DNA Damage; DNA Repair; Guanine; HeLa Cells; Humans; Oxidation-Reduction; Pyrimidine Dimers; RNA Polymerase II; Templates, Genetic; Thymine; Transcription, Genetic

2004
Cellular repair of oxidatively induced DNA base lesions is defective in prostate cancer cell lines, PC-3 and DU-145.
    Carcinogenesis, 2004, Volume: 25, Issue:8

    Topics: Adenine; Antioxidants; Blotting, Western; Catalase; Cell Division; Cell Line, Tumor; Cell Nucleus; Comet Assay; Cytosine; DNA; DNA Damage; Dose-Response Relationship, Drug; Electron Transport Complex IV; Gas Chromatography-Mass Spectrometry; Glutathione Peroxidase; Guanine; Humans; Kinetics; Male; Mitochondria; Oxygen; Polymorphism, Genetic; Prostatic Neoplasms; Superoxide Dismutase; Time Factors

2004
DNA damage levels and biochemical repair capacities associated with XRCC1 deficiency.
    Biochemistry, 2005, Nov-01, Volume: 44, Issue:43

    Topics: Adenine; Animals; Binding Sites; Cell Extracts; Cell Line; Cricetinae; Cytosine; DNA Damage; DNA Repair; DNA-Binding Proteins; Female; Guanine; Mutation; Ovary; Time Factors; Uracil; X-ray Repair Cross Complementing Protein 1

2005