5-hydroxy-6-8-11-14-eicosatetraenoic-acid has been researched along with isoxicam* in 1 studies
1 other study(ies) available for 5-hydroxy-6-8-11-14-eicosatetraenoic-acid and isoxicam
| Article | Year |
|---|---|
Effects of isoxicam and other non-steroidal anti-inflammatory drugs on arachidonic acid metabolism by rat peritoneal leucocytes.
Inhibition of prostaglandin formation from [14C]arachidonic acid by rat peritoneal leucocytes occurred with nonsteroidal anti-inflammatory drugs, their order of potency being indomethacin greater than piroxicam greater than naproxen greater than ibuprofen greater than isoxicam. At the lowest concentration tested (1 microgram ml-1), indomethacin markedly increased the accumulation of lipoxygenase products in the cell incubates. Naproxen, ibuprofen or piroxicam 1 or 10 micrograms ml-1 resulted in smaller increases of lipoxygenase products, and there was only a small rise with these concentrations of isoxicam. Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Hydroxyeicosatetraenoic Acids; Ibuprofen; In Vitro Techniques; Indomethacin; Leukocytes; Male; Naproxen; Piroxicam; Prostaglandins; Rats; Rats, Inbred Strains; Thiazines | 1985 |