Compounds > 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone

Page last updated: 2024-09-04

5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone and 5-demethylnobiletin

5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone has been researched along with 5-demethylnobiletin in 5 studies

Compound Research Comparison

Studies (5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone)	Trials (5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone)	Recent Studies (post-2010) (5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone)	Studies (5-demethylnobiletin)	Trials (5-demethylnobiletin)	Recent Studies (post-2010) (5-demethylnobiletin)
25	0	9	42	0	33

Research

Studies (5)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (40.00)	18.2507
2000's	1 (20.00)	29.6817
2010's	2 (40.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Beutler, JA; Boyd, MR; Cardellina, JH; Haemers, A; Hamel, E; Rajan, P; Roitman, JN; Vlietinck, AJ	1
Ash, K; Grohmann, K; Manthey, CL; Manthey, JA; Montanari, A	1
Dushenkov, S; Ho, CT; Lai, CS; Li, S; Lo, CY; Pan, MH	1
Dong, P; Guan, H; Ho, CT; Li, S; McClements, DJ; Pan, MH; Qiu, P; Xiao, H	2

Other Studies

5 other study(ies) available for 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone and 5-demethylnobiletin

Article	Year
Structure-activity requirements for flavone cytotoxicity and binding to tubulin. Journal of medicinal chemistry, 1998, Jun-18, Volume: 41, Issue:13 Topics: Antineoplastic Agents, Phytogenic; Biopolymers; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Flavonoids; Humans; Protein Binding; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured	1998
Polymethoxylated flavones derived from citrus suppress tumor necrosis factor-alpha expression by human monocytes. Journal of natural products, 1999, Volume: 62, Issue:3 Topics: Citrus; Cyclic AMP; Flavonoids; Humans; In Vitro Techniques; Lipopolysaccharides; Monocytes; Phosphodiesterase Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha	1999
Isolation and syntheses of polymethoxyflavones and hydroxylated polymethoxyflavones as inhibitors of HL-60 cell lines. Bioorganic & medicinal chemistry, 2007, May-15, Volume: 15, Issue:10 Topics: Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Cell Proliferation; Chromatography, High Pressure Liquid; Citrus; Flavones; Fruit; HL-60 Cells; Humans; Hydroxylation; Indicators and Reagents; Magnetic Resonance Spectroscopy; Plant Extracts; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet	2007
Inhibitory effects of 5-hydroxy polymethoxyflavones on colon cancer cells. Molecular nutrition & food research, 2010, Volume: 54 Suppl 2 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Cell Cycle; Cell Proliferation; Cell Survival; Colonic Neoplasms; Drug Screening Assays, Antitumor; Flavones; HCT116 Cells; HT29 Cells; Humans; Inhibitory Concentration 50; Necrosis; Protein Biosynthesis; Structure-Activity Relationship	2010
The p53-, Bax- and p21-dependent inhibition of colon cancer cell growth by 5-hydroxy polymethoxyflavones. Molecular nutrition & food research, 2011, Volume: 55, Issue:4 Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Cell Cycle; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Flavones; HCT116 Cells; Humans; Osmolar Concentration; Poly(ADP-ribose) Polymerases; Tumor Suppressor Protein p53	2011