5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone and 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone

5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone has been researched along with 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone in 2 studies

Compound Research Comparison

Studies (5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone)	Trials (5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone)	Recent Studies (post-2010) (5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone)	Studies (5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone)	Trials (5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone)	Recent Studies (post-2010) (5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone)
25	0	9	12	0	4

Protein Interaction Comparison

Protein	Taxonomy	5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone (IC50)
Tubulin beta-4A chain	Homo sapiens (human)	0.83
Tubulin beta chain	Homo sapiens (human)	0.83
Tubulin alpha-3C chain	Homo sapiens (human)	0.83
Tubulin alpha-1B chain	Homo sapiens (human)	0.83
Tubulin alpha-4A chain	Homo sapiens (human)	0.83
Tubulin beta-4B chain	Homo sapiens (human)	0.83
Tubulin beta-3 chain	Homo sapiens (human)	0.83
Tubulin beta-2A chain	Homo sapiens (human)	0.83
Tubulin beta-8 chain	Homo sapiens (human)	0.83
Tubulin alpha-3E chain	Homo sapiens (human)	0.83
Tubulin alpha-1A chain	Homo sapiens (human)	0.83
Tubulin alpha-1C chain	Homo sapiens (human)	0.83
Tubulin beta-6 chain	Homo sapiens (human)	0.83
Tubulin beta-2B chain	Homo sapiens (human)	0.83
Tubulin beta-1 chain	Homo sapiens (human)	0.83

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (100.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cosson, JP; Guéritte-Voegelein, F; Hadi, AH; Lichius, JJ; Montagnac, A; Païs, M; Sévenet, T; Thoison, O	1
Beutler, JA; Boyd, MR; Cardellina, JH; Haemers, A; Hamel, E; Rajan, P; Roitman, JN; Vlietinck, AJ	1

Other Studies

2 other study(ies) available for 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone and 5,3'-dihydroxy-3,6,7,8,4'-pentamethoxyflavone

Article	Year
Antimitotic and cytotoxic flavonols from Zieridium pseudobtusifolium and Acronychia porteri. Journal of natural products, 1994, Volume: 57, Issue:7 Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Flavonoids; Humans; KB Cells; Magnetic Resonance Spectroscopy; Malaysia; Mass Spectrometry; New Caledonia; Plant Leaves; Plants; Spectrophotometry, Ultraviolet; Tubulin; Tumor Cells, Cultured	1994
Structure-activity requirements for flavone cytotoxicity and binding to tubulin. Journal of medicinal chemistry, 1998, Jun-18, Volume: 41, Issue:13 Topics: Antineoplastic Agents, Phytogenic; Biopolymers; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Flavonoids; Humans; Protein Binding; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured	1998

Article

Year

Antimitotic and cytotoxic flavonols from Zieridium pseudobtusifolium and Acronychia porteri.

Journal of natural products, 1994, Volume: 57, Issue:7

Topics: Antineoplastic Agents, Phytogenic; Drug Screening Assays, Antitumor; Flavonoids; Humans; KB Cells; Magnetic Resonance Spectroscopy; Malaysia; Mass Spectrometry; New Caledonia; Plant Leaves; Plants; Spectrophotometry, Ultraviolet; Tubulin; Tumor Cells, Cultured

1994

Structure-activity requirements for flavone cytotoxicity and binding to tubulin.

Journal of medicinal chemistry, 1998, Jun-18, Volume: 41, Issue:13

Topics: Antineoplastic Agents, Phytogenic; Biopolymers; Cell Survival; Colchicine; Drug Screening Assays, Antitumor; Flavonoids; Humans; Protein Binding; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured

1998