Compounds > 5-hydroxy-2-n,n-dipropylaminotetralin
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5-hydroxy-2-n,n-dipropylaminotetralin and pergolide

5-hydroxy-2-n,n-dipropylaminotetralin has been researched along with pergolide in 1 studies

Compound Research Comparison

Studies
(5-hydroxy-2-n,n-dipropylaminotetralin)		Trials
(5-hydroxy-2-n,n-dipropylaminotetralin)		Recent Studies (post-2010)
(5-hydroxy-2-n,n-dipropylaminotetralin)		Studies
(pergolide)		Trials
(pergolide)		Recent Studies (post-2010) (pergolide)
420384512387

Protein Interaction Comparison

ProteinTaxonomy5-hydroxy-2-n,n-dipropylaminotetralin (IC50)pergolide (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.379
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.385
Alpha-2A adrenergic receptorHomo sapiens (human)0.264
Cytochrome P450 2D6Homo sapiens (human)0.2
D(2) dopamine receptorHomo sapiens (human)0.111
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.385
Alpha-2B adrenergic receptorHomo sapiens (human)0.064
Alpha-2C adrenergic receptorHomo sapiens (human)1.41
DRattus norvegicus (Norway rat)0.0031
D(3) dopamine receptorRattus norvegicus (Norway rat)0.0031
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.2
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.041
D(2) dopamine receptorBos taurus (cattle)0.0603
D(1A) dopamine receptorHomo sapiens (human)0.679
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.041
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.041
Alpha-1D adrenergic receptorHomo sapiens (human)1.513
D(1B) dopamine receptorRattus norvegicus (Norway rat)0.0031
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.014
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.379
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.2
5-hydroxytryptamine receptor 1DRattus norvegicus (Norway rat)0.385
D(4) dopamine receptorRattus norvegicus (Norway rat)0.0031
5-hydroxytryptamine receptor 1FRattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 6Rattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 7 Rattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 5ARattus norvegicus (Norway rat)0.385
5-hydroxytryptamine receptor 5BRattus norvegicus (Norway rat)0.385
D(3) dopamine receptorHomo sapiens (human)0.0054
5-hydroxytryptamine receptor 3ARattus norvegicus (Norway rat)0.385
Alpha-synucleinHomo sapiens (human)7.9
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.076
5-hydroxytryptamine receptor 6Homo sapiens (human)0.039
D(2) dopamine receptorRattus norvegicus (Norway rat)0.0031
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.1202
5-hydroxytryptamine receptor 4 Rattus norvegicus (Norway rat)0.385
DBos taurus (cattle)0.0603
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.385
5-hydroxytryptamine receptor 3BRattus norvegicus (Norway rat)0.385

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Closse, A; Frick, W; Jaton, A; Seiler, MP; Stoll, AP; Vigouret, JM1

Other Studies

1 other study(ies) available for 5-hydroxy-2-n,n-dipropylaminotetralin and pergolide

ArticleYear
Structure-activity relationships of dopaminergic 5-hydroxy-2-aminotetralin derivatives with functionalized N-alkyl substituents.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:6

    Topics: Animals; Antiparkinson Agents; Binding Sites; Cattle; In Vitro Techniques; Naphthalenes; Rats; Receptors, Dopamine; Structure-Activity Relationship; Tetrahydronaphthalenes

1986