Page last updated: 2024-09-03

5-hydroxy-1-methyl-2-(di-n-propylamino)tetralin and 8-hydroxy-2-(di-n-propylamino)tetralin

5-hydroxy-1-methyl-2-(di-n-propylamino)tetralin has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 4 studies

Compound Research Comparison

Studies
(5-hydroxy-1-methyl-2-(di-n-propylamino)tetralin)
Trials
(5-hydroxy-1-methyl-2-(di-n-propylamino)tetralin)
Recent Studies (post-2010)
(5-hydroxy-1-methyl-2-(di-n-propylamino)tetralin)
Studies
(8-hydroxy-2-(di-n-propylamino)tetralin)
Trials
(8-hydroxy-2-(di-n-propylamino)tetralin)
Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin)
5003,5307389

Protein Interaction Comparison

ProteinTaxonomy5-hydroxy-1-methyl-2-(di-n-propylamino)tetralin (IC50)8-hydroxy-2-(di-n-propylamino)tetralin (IC50)
5-hydroxytryptamine receptor 1AHomo sapiens (human)0.0012
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.0032
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorBos taurus (cattle)0.8
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.81
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.81
D(2) dopamine receptorRattus norvegicus (Norway rat)2.8959
Lysosomal alpha-glucosidaseBos taurus (cattle)0.0021

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andersson, B; Arvidsson, LE; Carlsson, A; Clark, D; Hacksell, U; Hjorth, S; Johansson, AM; Sanchez, D; Svensson, K; Wikström, H1
Baldessarini, RJ; Campbell, A; Froimowitz, M; Gao, YG; Neumeyer, JL1
Baldessarini, RJ; Froimowitz, M; Neumeyer, JL1
Andersson, B; Arvidsson, LE; Carlsson, A; Clark, D; Hacksell, U; Hjorth, S; Johansson, AM; Nilsson, JL; Sanchez, D; Svensson, K1

Other Studies

4 other study(ies) available for 5-hydroxy-1-methyl-2-(di-n-propylamino)tetralin and 8-hydroxy-2-(di-n-propylamino)tetralin

ArticleYear
(+)-UH 232 and (+)-UH 242: novel stereoselective dopamine receptor antagonists with preferential action on autoreceptors.
    Journal of neural transmission, 1986, Volume: 65, Issue:1

    Topics: 4-Butyrolactone; 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Apomorphine; Behavior, Animal; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Male; Motor Activity; Naphthalenes; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Dopamine; Reserpine; Serotonin; Stereoisomerism; Tetrahydronaphthalenes

1986
Neuropharmacology and stereochemistry of dopamine receptor agonist and antagonist enantiomeric pairs.
    Journal of receptor research, 1988, Volume: 8, Issue:1-4

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Aporphines; Dopamine; Molecular Conformation; Naphthalenes; Piperidines; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes

1988
A stereochemical explanation of the dopamine agonist and antagonist activity of stereoisomeric pairs.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:9

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Apomorphine; Chemical Phenomena; Chemistry; Dopamine; Dopamine Antagonists; Molecular Conformation; Naphthalenes; Piperidines; Receptors, Dopamine; Stereoisomerism; Structure-Activity Relationship; Tetrahydronaphthalenes; Thermodynamics

1986
Novel dopamine receptor agonists and antagonists with preferential action on autoreceptors.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:8

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Dihydroxyphenylalanine; Male; Motor Activity; Naphthalenes; Rats; Rats, Inbred Strains; Receptors, Dopamine; Stereoisomerism; Tetrahydronaphthalenes

1985