Page last updated: 2024-09-03

5-fluorowillardiine and willardiine

5-fluorowillardiine has been researched along with willardiine in 3 studies

Compound Research Comparison

Studies
(5-fluorowillardiine)
Trials
(5-fluorowillardiine)
Recent Studies (post-2010)
(5-fluorowillardiine)
Studies
(willardiine)
Trials
(willardiine)
Recent Studies (post-2010) (willardiine)
290843010

Protein Interaction Comparison

ProteinTaxonomy5-fluorowillardiine (IC50)willardiine (IC50)
Chain A, glutamate receptor 2Rattus norvegicus (Norway rat)4.76
Chain A, glutamate receptor 2Rattus norvegicus (Norway rat)4.76
Chain A, glutamate receptor 2Rattus norvegicus (Norway rat)4.76
Chain A, glutamate receptor 2Rattus norvegicus (Norway rat)4.76

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bleakman, D; Deverill, M; Hoo, K; Jane, DE; Kamboj, R; Mandelzys, A1
Banke, TG; Gouaux, E; Jin, R; Mayer, ML; Traynelis, SF1
Butini, S; Campiani, G; Christensen, JK; Coccone, SS; De Angelis, M; Fiorini, I; Gemma, S; Guarino, E; Morelli, E; Novellino, E; Pickering, DS; Schousboe, A; Trotta, F1

Other Studies

3 other study(ies) available for 5-fluorowillardiine and willardiine

ArticleYear
Synthesis of willardiine and 6-azawillardiine analogs: pharmacological characterization on cloned homomeric human AMPA and kainate receptor subtypes.
    Journal of medicinal chemistry, 1997, Oct-24, Volume: 40, Issue:22

    Topics: Alanine; Cell Line; Excitatory Amino Acid Agonists; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Pyrimidinones; Radioligand Assay; Receptors, AMPA; Receptors, Kainic Acid; Recombinant Proteins; Triazines; Uracil

1997
Structural basis for partial agonist action at ionotropic glutamate receptors.
    Nature neuroscience, 2003, Volume: 6, Issue:8

    Topics: Alanine; Animals; Cell Line; Crystallography, X-Ray; Electric Conductivity; Electrophysiology; Humans; Ion Channels; Ligands; Models, Biological; Molecular Conformation; Oocytes; Pyrimidinones; Receptors, AMPA; Uracil; Xenopus laevis

2003
1H-cyclopentapyrimidine-2,4(1H,3H)-dione-related ionotropic glutamate receptors ligands. structure-activity relationships and identification of potent and Selective iGluR5 modulators.
    Journal of medicinal chemistry, 2008, Oct-23, Volume: 51, Issue:20

    Topics: Animals; Cell Line; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Humans; Ligands; Molecular Structure; Oocytes; Pyrimidinones; Rats; Receptors, Glutamate; Spodoptera; Structure-Activity Relationship; Thiophenes; Xenopus laevis

2008