5-fluorouridine 5'-phosphate has been researched along with fluorouracil in 12 studies
| Studies (5-fluorouridine 5'-phosphate) | Trials (5-fluorouridine 5'-phosphate) | Recent Studies (post-2010) (5-fluorouridine 5'-phosphate) | Studies (fluorouracil) | Trials (fluorouracil) | Recent Studies (post-2010) (fluorouracil) |
|---|---|---|---|---|---|
| 24 | 0 | 2 | 45,562 | 9,307 | 14,663 |
| Protein | Taxonomy | 5-fluorouridine 5'-phosphate (IC50) | fluorouracil (IC50) |
|---|---|---|---|
| Epidermal growth factor receptor | Homo sapiens (human) | 0.32 | |
| Thymidylate synthase | Mus musculus (house mouse) | 1.58 | |
| Aromatase | Homo sapiens (human) | 0.63 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (66.67) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hoshi, A; Kuretani, K; Yoshida, M | 1 |
| Laurensse, EJ; Peters, GJ; Pinedo, HM; van Groeningen, CJ | 1 |
| Martin, DS; Sawyer, RC; Stolfi, RL | 1 |
| Handschumacher, RE; Hyde, CM; Moir, RD; Schwartz, PM; Turek, PJ | 1 |
| Alderfer, JL; Loomis, RE | 1 |
| Danenberg, PV; Heidelberger, C; Moran, RG | 1 |
| Au, JL; Luccioni, CM; Rustum, YM; Wientjes, MG | 1 |
| Danenberg, PV; Shani, J | 1 |
| Fukushima, M; Shimamoto, Y; Shirasaka, T | 1 |
| Ghoshal, K; Jacob, ST | 1 |
| Hamada, H; Inaba, M; Sadata, A; Sawada, H | 1 |
| Benz, C; Cadman, E; Heimer, R; O'Shaughnessy, J | 1 |
1 review(s) available for 5-fluorouridine 5'-phosphate and fluorouracil
| Article | Year |
|---|---|
Fluorinated pyrimidines and their nucleosides.
Topics: Animals; Enzyme Activation; Fluorouracil; Humans; Neoplasms; Pyrimidines; RNA; Thymidylate Synthase; Transcription, Genetic; Uracil Nucleotides; Uridine Triphosphate | 1983 |
11 other study(ies) available for 5-fluorouridine 5'-phosphate and fluorouracil
| Article | Year |
|---|---|
Mode of action of 5-fluorouridine 5'-phosphate in vivo and in vitro.
Topics: Animals; Antimetabolites, Antineoplastic; Cells, Cultured; Cytarabine; Fluorouracil; Leukemia L1210; Leukemia, Experimental; Mice; Nucleic Acid Precursors; Uracil Nucleotides | 1978 |
A comparison of 5-fluorouracil metabolism in human colorectal cancer and colon mucosa.
Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Colon; Colonic Neoplasms; Fluorodeoxyuridylate; Fluorouracil; Humans; Intestinal Mucosa; Middle Aged; Orotate Phosphoribosyltransferase; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Pyrimidine Phosphorylases; Rectal Neoplasms; Ribosemonophosphates; Uracil Nucleotides; Uridine Triphosphate | 1991 |
Effect of L-histidinol on the metabolism of 5-fluorouracil in the BALB/c x DBA/8 F1 murine tumor system.
Topics: Animals; DNA, Neoplasm; Fluorouracil; Histidinol; Imidazoles; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Neoplasms, Experimental; Phosphoribosyl Pyrophosphate; RNA, Neoplasm; Uracil Nucleotides | 1988 |
Role of uridine phosphorylase in the anabolism of 5-fluorouracil.
Topics: Animals; Bone Marrow; Colonic Neoplasms; Diphosphates; Female; Fluorouracil; Kinetics; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Orotate Phosphoribosyltransferase; Pentosyltransferases; Peritoneal Neoplasms; Rats; Uracil Nucleotides; Uridine Kinase; Uridine Phosphorylase | 1985 |
Halogenated nucleic acids: effects of 5-fluorouracil on the conformation and properties of a polyribonucleotide and its constituents.
Topics: Fluorouracil; Molecular Conformation; Nucleic Acid Conformation; Poly U; Polydeoxyribonucleotides; Uracil Nucleotides; Uridine | 1986 |
Reversed-phase ion-pair high-performance liquid chromatographic assay of 5-fluorouracil, 5'-deoxy-5-fluorouridine, their nucleosides, mono-, di-, and triphosphate nucleotides with a mixture of quaternary ammonium ions.
Topics: Chromatography, High Pressure Liquid; Deoxyuracil Nucleotides; Floxuridine; Fluorodeoxyuridylate; Fluorouracil; Isomerism; Structure-Activity Relationship; Uracil Nucleotides; Uridine | 1982 |
Evidence that intracellular synthesis of 5-fluorouridine-5'-phosphate from 5-fluorouracil and 5-fluorouridine is compartmentalized.
Topics: Animals; Cell Compartmentation; Cell Nucleus; Chromatography, Affinity; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cytosol; Fluorouracil; Leukemia L1210; Mice; RNA, Neoplasm; Sepharose; Uracil Nucleotides; Uridine | 1984 |
Inhibition by oxonic acid of gastrointestinal toxicity of 5-fluorouracil without loss of its antitumor activity in rats.
Topics: Administration, Oral; Animals; Digestive System; Fluorouracil; Infusions, Intravenous; Liver; Male; Oxonic Acid; Phosphorylation; Rats; RNA; Sarcoma, Yoshida; Uracil Nucleotides | 1993 |
Specific inhibition of pre-ribosomal RNA processing in extracts from the lymphosarcoma cells treated with 5-fluorouracil.
Topics: Animals; Base Sequence; Cell Division; Cell Nucleus; DNA, Ribosomal; Fluorouracil; Lymphoma, Non-Hodgkin; Mice; Molecular Sequence Data; RNA Precursors; RNA, Neoplasm; RNA, Ribosomal; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Uracil Nucleotides; Uridine Triphosphate | 1994 |
Circumvention of 5-fluorouracil resistance in human stomach cancer cells by uracil phosphoribosyltransferase gene transduction.
Topics: Adenoviridae; Cytosol; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Escherichia coli; Fluorouracil; Genes, Reporter; Genetic Therapy; Genetic Vectors; Humans; Inhibitory Concentration 50; Pentosyltransferases; Phosphoribosyl Pyrophosphate; Recombinant Proteins; Stomach Neoplasms; Transduction, Genetic; Transfection; Tumor Cells, Cultured; Uracil Nucleotides | 1999 |
Effect of de novo purine synthesis inhibitors on 5-fluorouracil metabolism and cytotoxicity.
Topics: Alanine; Animals; Azaserine; Cell Line, Tumor; Cell Survival; Diazooxonorleucine; Dose-Response Relationship, Drug; Fluorouracil; Methotrexate; Nucleic Acid Synthesis Inhibitors; Purines; Thioinosine; Thionucleotides; Uracil Nucleotides | 1981 |