5-fluoropyrimidine has been researched along with fluorouracil in 24 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (16.67) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 8 (33.33) | 29.6817 |
| 2010's | 6 (25.00) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Machover, D | 1 |
| Holbrook, CT; Klann, RC; Nyce, J | 1 |
| Lönn, S; Lönn, U | 1 |
| Baker, L; Poplin, E | 1 |
| Danenberg, PV; Heidelberger, C; Moran, RG | 1 |
| Day, JL; Mandel, HG; Maybaum, J; Sadee, W; Ullman, B | 1 |
| Schwartz, EL; Wadler, S | 1 |
| Cao, S; Gibbs, JF; Rustum, YM; Slocum, HK | 1 |
| Ciccolini, J; Dubreuil, A; Etienne, MC; Fischel, JL; Formento, JL; Formento, P; Magné, N; Marchetti, S; Milano, G; Renée, N; Tiffon, C | 1 |
| Asada, Y; Fujisawa, K; Iida, Y; Kasahara, Y; Mitsui, T; Miura, S; Munemoto, Y; Ohata, K; Saito, H | 1 |
| Eliason, JF; Megyeri, A | 1 |
| Diasio, RB; Soong, R | 1 |
| Barbado, M; Boisdron-Celle, M; Gamelin, E; Lorimier, G; Morel, A; Preisser, L; Verriele, V | 1 |
| Ikeda, M; Morizane, C; Okusaka, T; Ueno, H | 1 |
| Cheng, J; Li, J; Wu, CP; Wu, Q; Xu, LG; Xu, N; Zhang, W; Zhao, ZY | 1 |
| Cavalli, F; Saletti, P; Sessa, C | 1 |
| Bao, HY; Chen, J; Deng, J; Fang, WJ; Huang, S; Mou, HB; Shen, P; Shi, GM; Xu, N; Yu, LF; Zhang, XC | 1 |
| Ng, S; O'bichere, A; Platell, C; Tebbutt, N | 1 |
| Broadwater, G; Clough, RW; Czito, BG; Guy, CD; Papalezova, KT; Papavassiliou, P; Tyler, DS; White, RR; Willett, CG; Zagar, TM | 1 |
| El-Rayes, BF; Zafar, SF | 1 |
| Ali, JA; Allison, HC; Burgess, K; Creek, DJ; De Koning, HP; Field, MC; Mäser, P | 1 |
| Huang, ZP; Li, GX; Wang, F; Wang, ZX; Xu, RH; Zhou, ZW | 1 |
| Abdhaghighi, MJ; Jalali, H; Janbabaei, G; Negarandeh, R; Nosrati, A; Saghafi, F; Salehifar, E | 1 |
| Jin, J; Zhang, Y; Zheng, T; Zhou, L | 1 |
8 review(s) available for 5-fluoropyrimidine and fluorouracil
| Article | Year |
|---|---|
Developments of the fluoropyrimidines as inhibitors of thymidylate synthetase: pharmacologic and clinical aspects.
Topics: Animals; Antineoplastic Agents; Colorectal Neoplasms; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leucovorin; Organoplatinum Compounds; Prodrugs; Pyrimidines; Thymidylate Synthase | 1991 |
Colon cancer: medical therapy.
Topics: Colonic Neoplasms; Fluorouracil; Humans; Interleukin-2; Pyrimidines | 1988 |
Fluorinated pyrimidines and their nucleosides.
Topics: Animals; Enzyme Activation; Fluorouracil; Humans; Neoplasms; Pyrimidines; RNA; Thymidylate Synthase; Transcription, Genetic; Uracil Nucleotides; Uridine Triphosphate | 1983 |
Potential for predicting toxicity and response of fluoropyrimidines in patients.
Topics: Fluorouracil; Humans; Neoplasms; Predictive Value of Tests; Pyrimidines | 2004 |
Advances and challenges in fluoropyrimidine pharmacogenomics and pharmacogenetics.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Fluorouracil; Humans; Pharmacogenetics; Pyrimidines | 2005 |
[5 -fluoropyrimidines for treatment of biliary tract cancers].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Capecitabine; Clinical Trials as Topic; Deoxycytidine; Drug Combinations; Fluorouracil; Humans; Oxonic Acid; Pyridines; Pyrimidines; Tegafur; Uracil | 2006 |
Chemotherapeutic strategies in advanced or metastatic pancreatic adenocarcinoma.
Topics: Adenocarcinoma; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cetuximab; Deoxycytidine; Fluorouracil; Gemcitabine; Humans; Molecular Targeted Therapy; Pancreatic Neoplasms; Pyrimidines | 2014 |
Comparison between Fluoropyrimidine-Cisplatin and Gemcitabine-Cisplatin as First-Line Chemotherapy for Advanced Biliary Tract Cancer: A Meta-Analysis.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Biliary Tract Neoplasms; Capecitabine; Cisplatin; Deoxycytidine; Female; Fluorouracil; Gemcitabine; Humans; Male; Middle Aged; Progression-Free Survival; Pyrimidines; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Rate; Treatment Outcome; Young Adult | 2020 |
2 trial(s) available for 5-fluoropyrimidine and fluorouracil
| Article | Year |
|---|---|
[Multicenter phase II study of modified FOLFIRI regimen in the advanced colorectal cancer patient refractory to fluoropyrimidine and oxaliplatin].
Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colonic Neoplasms; Diarrhea; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Nausea; Neoplasm Staging; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Prospective Studies; Pyrimidines; Rectal Neoplasms; Remission Induction; Treatment Failure | 2006 |
Phase II study of FOLFIRI regimen in patients with advanced colorectal cancer refractory to fluoropyrimidine and oxaliplatin.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; China; Colorectal Neoplasms; Diarrhea; Disease-Free Survival; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Nausea; Neutropenia; Organoplatinum Compounds; Oxaliplatin; Pyrimidines; Survival; Vomiting; Young Adult | 2011 |
14 other study(ies) available for 5-fluoropyrimidine and fluorouracil
| Article | Year |
|---|---|
Biochemical modulation of 5-fluoropyrimidine toxicity by dehydroepiandrosterone in human colonic adenocarcinoma cells.
Topics: Adenocarcinoma; Carbon Radioisotopes; Colonic Neoplasms; Dehydroepiandrosterone; Fluorouracil; Humans; Interphase; Pyrimidines; Thymidine; Thymidine Monophosphate; Tumor Cells, Cultured; Uracil | 1990 |
Increased levels of DNA lesions induced by leucovorin-5-fluoropyrimidine in human colon adenocarcinoma.
Topics: Adenocarcinoma; Aphidicolin; Cell Line; Cell Survival; Colonic Neoplasms; Diterpenes; DNA; DNA Damage; Drug Synergism; Floxuridine; Fluorouracil; Humans; Leucovorin; Pyrimidines; Thymidine | 1988 |
Regulation of RNA- and DNA-directed actions of 5-fluoropyrimidines in mouse T-lymphoma (S-49) cells.
Topics: Animals; Cell Cycle; DNA, Neoplasm; Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Leukemia, Experimental; Lymphoma; Mice; Pyrimidine Nucleotides; Pyrimidines; RNA, Neoplasm; Thymidine | 1980 |
Role of interferon as a modulator of fluoropyrimidines: reply to a recent editorial.
Topics: Antineoplastic Combined Chemotherapy Protocols; Colorectal Neoplasms; Fluorouracil; Humans; Interferon-alpha; Interferon-beta; Pyrimidines | 1997 |
Image analysis for quantitation of solid tumor drug sensitivity.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Fluorouracil; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Osmolar Concentration; Pyrimidines; Rats; Single-Blind Method | 1999 |
ZD1839 (Iressa) modifies the activity of key enzymes linked to fluoropyrimidine activity: rational basis for a new combination therapy with capecitabine.
Topics: Administration, Oral; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Cell Cycle; Cell Division; Cell Line, Tumor; Cell Survival; Deoxycytidine; DNA Primers; Floxuridine; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Models, Chemical; Polymerase Chain Reaction; Pyrimidines; Quinazolines; RNA; RNA, Messenger; Time Factors; Transcription, Genetic | 2003 |
Significance of postoperative adjuvant immunochemotherapy after curative resection of colorectal cancers: identification of responders incorporating the age factor.
Topics: Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; CA-19-9 Antigen; Carcinoembryonic Antigen; Chemotherapy, Adjuvant; Colonic Neoplasms; Complement C3; Complement C4; Female; Fluorouracil; Humans; Immunotherapy; Lymphocyte Activation; Male; Medroxyprogesterone Acetate; Melphalan; Middle Aged; Mitomycin; Multivariate Analysis; Neoplasm Proteins; Phytohemagglutinins; Prognosis; Proportional Hazards Models; Proteoglycans; Pyrimidines; Time Factors; Treatment Outcome | 2004 |
Tumor quantification of several fluoropyrimidines resistance gene expression with a unique quantitative RT-PCR method. Implications for pretherapeutic determination of tumor resistance phenotype.
Topics: Antimetabolites, Antineoplastic; Biopsy; Carcinoma; Colorectal Neoplasms; DNA Primers; DNA, Complementary; Drug Resistance, Neoplasm; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Oligonucleotide Array Sequence Analysis; Phenotype; Pyrimidines; Reverse Transcriptase Polymerase Chain Reaction | 2006 |
Commentary 2008: 25 or 50 years later?
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; Colorectal Neoplasms; Fluorouracil; Humans; Liver Neoplasms, Experimental; Medical Oncology; Pyrimidines | 2008 |
Changing management and survival in patients with stage IV colorectal cancer.
Topics: Adenocarcinoma; Aged; Anastomosis, Surgical; Antineoplastic Agents; Australia; Camptothecin; Capecitabine; Chemotherapy, Adjuvant; Cohort Studies; Colorectal Neoplasms; Colostomy; Deoxycytidine; Female; Fluorouracil; Humans; Irinotecan; Male; Multivariate Analysis; Neoplasm Metastasis; Organoplatinum Compounds; Oxaliplatin; Palliative Care; Proportional Hazards Models; Pyrimidines; Radiotherapy, Adjuvant; Survival Rate | 2011 |
Resected pancreatic neuroendocrine tumors: patterns of failure and disease-related outcomes with or without radiotherapy.
Topics: Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Male; Middle Aged; Neoadjuvant Therapy; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrimidines; Radiotherapy Dosage; Radiotherapy, Adjuvant; Retrospective Studies; Treatment Failure | 2012 |
Pyrimidine salvage in Trypanosoma brucei bloodstream forms and the trypanocidal action of halogenated pyrimidines.
Topics: Biological Transport; Fluorouracil; Genome-Wide Association Study; Glycosylation; Nucleoside Transport Proteins; Pyrimidines; Trypanosoma brucei brucei; Uracil; Uridine | 2013 |
Validation of a nomogram for selecting patients for chemotherapy after D2 gastrectomy for cancer.
Topics: Aftercare; Antineoplastic Combined Chemotherapy Protocols; Capecitabine; Chemotherapy, Adjuvant; China; Clinical Decision-Making; Deoxycytidine; Female; Fluorouracil; Gastrectomy; Humans; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Nomograms; Organoplatinum Compounds; Oxaloacetates; Patient Selection; Postoperative Care; Pyrimidines; Stomach Neoplasms | 2017 |
Evaluation of adverse effects of chemotherapy regimens of 5-fluoropyrimidines derivatives and their association with DPYD polymorphisms in colorectal cancer patients.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Cross-Sectional Studies; Dihydrouracil Dehydrogenase (NADP); Drug-Related Side Effects and Adverse Reactions; Female; Fluorouracil; Humans; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Pyrimidines | 2020 |