Page last updated: 2024-08-25

5-fluoroorotic acid and uridine

5-fluoroorotic acid has been researched along with uridine in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's3 (30.00)18.2507
2000's2 (20.00)29.6817
2010's1 (10.00)24.3611
2020's1 (10.00)2.80

Authors

AuthorsStudies
Hsiao, WL; Krooth, RS; Potvin, BW1
Bennett, JE; Edman, JC; Kwon-Chung, KJ; Varma, A1
de Graaff, LH; Gruber, F; Kubicek, CP; Visser, J1
Gómez, ZM; Rathod, PK1
Hubbert, T; Khatri, A; Milhous, WK; Rathod, PK1
Gou, X; Zhang, Y1
BASCH, RS; KARNOFSKY, DA1
Engelbrecher, A; Häuser, R; Titz, B; Uetz, P1
Fairlamb, AH; Ong, HB; Patterson, S; Sienkiewicz, N; Wyllie, S1
Bao, G; Chanda, MK; Lee, CM; Martin, R; Patterson, JO; Porteus, MH; Srifa, W; Wiebking, V1

Other Studies

10 other study(ies) available for 5-fluoroorotic acid and uridine

ArticleYear
Resistance to 5-fluoroorotic acid and pyrimidine auxotrophy: a new bidirectional selective system for mammalian cells.
    Somatic cell genetics, 1979, Volume: 5, Issue:5

    Topics: Animals; Clone Cells; Culture Media; Drug Resistance; Leukemia, Experimental; Mice; Orotic Acid; Phenotype; Uridine

1979
Selection of ura5 and ura3 mutants from the two varieties of Cryptococcus neoformans on 5-fluoroorotic acid medium.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1992, Volume: 30, Issue:1

    Topics: Animals; Blotting, Southern; Cryptococcus neoformans; Culture Media; Deoxyribonuclease EcoRI; Deoxyribonucleases, Type II Site-Specific; DNA, Fungal; Humans; Mutation; Nucleic Acid Hybridization; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Restriction Mapping; Transformation, Genetic; Uracil; Uridine

1992
The development of a heterologous transformation system for the cellulolytic fungus Trichoderma reesei based on a pyrG-negative mutant strain.
    Current genetics, 1990, Volume: 18, Issue:1

    Topics: Blotting, Southern; Chromatography, Thin Layer; Drug Resistance, Microbial; Genes, Fungal; Mutation; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Transformation, Genetic; Trichoderma; Uridine

1990
Antimalarial activity of a combination of 5-fluoroorotate and uridine in mice.
    Antimicrobial agents and chemotherapy, 1990, Volume: 34, Issue:7

    Topics: Animals; Drug Combinations; Malaria; Male; Mice; Orotic Acid; Plasmodium yoelii; Uridine

1990
Selective activity of 5-fluoroorotic acid against Plasmodium falciparum in vitro.
    Antimicrobial agents and chemotherapy, 1989, Volume: 33, Issue:7

    Topics: Animals; Antimalarials; Cell Survival; Cells, Cultured; Chloroquine; Humans; Orotic Acid; Plasmodium falciparum; Tumor Cells, Cultured; Uridine

1989
[Characterization and transformation of anti-FOA strain of Aspergillus awamori].
    Wei sheng wu xue bao = Acta microbiologica Sinica, 2000, Volume: 40, Issue:2

    Topics: Aspergillus; Culture Media; Drug Resistance, Microbial; Fungal Proteins; Mutation; Orotic Acid; Spores, Fungal; Transformation, Genetic; Ultraviolet Rays; Uridine

2000
Effects of 5-fluorodeoxyuridine and related halogenated pyrimidines on the sand-dollar embryo.
    The Journal of biophysical and biochemical cytology, 1960, Volume: 7

    Topics: Cytidine; DNA; Female; Floxuridine; Fluorouracil; Humans; Orotic Acid; Pregnancy; Pyrimidines; Thymidine; Thymine; Uridine

1960
The Escherichia coli protein YjjG is a house-cleaning nucleotidase in vivo.
    FEMS microbiology letters, 2007, Volume: 270, Issue:1

    Topics: Azacitidine; Bromodeoxyuridine; Decitabine; Deoxyuridine; DNA Damage; Escherichia coli; Escherichia coli Proteins; Fluorouracil; Models, Biological; Molecular Structure; Mutation; N-Glycosyl Hydrolases; Nucleotidases; Orotic Acid; Substrate Specificity; Thymidine Monophosphate; Uridine

2007
Trypanosoma brucei (UMP synthase null mutants) are avirulent in mice, but recover virulence upon prolonged culture in vitro while retaining pyrimidine auxotrophy.
    Molecular microbiology, 2013, Volume: 90, Issue:2

    Topics: Amides; Animals; Biological Transport; Cell Line; Deoxyuridine; Fluorouracil; Gene Knockout Techniques; Mice; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Pyrazoles; Pyrimidines; Ribonucleosides; Ribose; Transfection; Trypanocidal Agents; Trypanosoma brucei brucei; Uracil; Uridine; Uridine Monophosphate; Virulence

2013
Metabolic engineering generates a transgene-free safety switch for cell therapy.
    Nature biotechnology, 2020, Volume: 38, Issue:12

    Topics: Animals; Base Sequence; Cell Proliferation; Cell- and Tissue-Based Therapy; Gene Editing; Gene Targeting; Genome, Human; Humans; K562 Cells; Male; Metabolic Engineering; Mice; Multienzyme Complexes; Orotate Phosphoribosyltransferase; Orotic Acid; Orotidine-5'-Phosphate Decarboxylase; Pluripotent Stem Cells; Transgenes; Uridine

2020