Compounds > 5-fluoromethylornithine
Page last updated: 2024-09-03

5-fluoromethylornithine and putrescine

5-fluoromethylornithine has been researched along with putrescine in 5 studies

Compound Research Comparison

Studies
(5-fluoromethylornithine)		Trials
(5-fluoromethylornithine)		Recent Studies (post-2010)
(5-fluoromethylornithine)		Studies
(putrescine)		Trials
(putrescine)		Recent Studies (post-2010) (putrescine)
22024,64327826

Protein Interaction Comparison

ProteinTaxonomy5-fluoromethylornithine (IC50)putrescine (IC50)
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001
Chain A, S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAINHomo sapiens (human)0.2001
Chain B, S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAINHomo sapiens (human)0.2001

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19901 (20.00)18.7374
1990's3 (60.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Daune, G; Gerhart, F; Seiler, N1
Hornsperger, JM; Knoedgen, B; Sablone, M; Sarhan, S; Seiler, N1
Alakuijala, L; Alhonen, L; Halmekytö, M; Halonen, T; Jänne, J; Kauppinen, R; MacDonald, E; Miettinen, R; Sinervirta, R; Sivenius, J1
Alakuijala, L; Alhonen, L; Halmekytö, M; Jänne, J1
Ando, A; Furuta, K; Igarashi, K; Ito, S; Kaneko, S; Maeda, M; Matsumura, M; Nishimura, K; Okuda-Ashitaka, E; Suzuki, M1

Other Studies

5 other study(ies) available for 5-fluoromethylornithine and putrescine

ArticleYear
5-Fluoromethylornithine, an irreversible and specific inhibitor of L-ornithine:2-oxo-acid aminotransferase.
    The Biochemical journal, 1988, Jul-15, Volume: 253, Issue:2

    Topics: Animals; Brain; Female; In Vitro Techniques; Liver; Male; Mice; Ornithine; Ornithine-Oxo-Acid Transaminase; Putrescine; Rats; Rats, Inbred Strains; Time Factors; Transaminases

1988
Enhanced endogenous ornithine concentrations protect against tonic seizures and coma in acute ammonia intoxication.
    Pharmacology & toxicology, 1993, Volume: 72, Issue:2

    Topics: 3-Mercaptopropionic Acid; Ammonia; Animals; Brain Chemistry; Coma; Dialysis; Dizocilpine Maleate; Electroshock; Epilepsy, Generalized; Female; Glutamate-Ammonia Ligase; Methionine Sulfoximine; Mice; N-Methylaspartate; Ornithine; Ornithine-Oxo-Acid Transaminase; Pentylenetetrazole; Postural Balance; Putrescine; Strychnine

1993
Elevated seizure threshold and impaired spatial learning in transgenic mice with putrescine overproduction in the brain.
    The European journal of neuroscience, 1993, Sep-01, Volume: 5, Issue:9

    Topics: Animals; Brain; Differential Threshold; Electroshock; Escape Reaction; Immunohistochemistry; Learning; Mice; Mice, Transgenic; Motor Activity; Ornithine; Ornithine Decarboxylase Inhibitors; Pentylenetetrazole; Polyamines; Putrescine; Reference Values; Seizures; Space Perception; Swimming

1993
Transgenic mice over-producing putrescine in their tissues do not convert the diamine into higher polyamines.
    The Biochemical journal, 1993, Apr-15, Volume: 291 ( Pt 2)

    Topics: Animals; Brain; Diamines; Gene Expression; Male; Mice; Mice, Transgenic; Ornithine; Ornithine Decarboxylase; Ornithine-Oxo-Acid Transaminase; Polyamines; Putrescine; Spermidine; Spermine; Testis

1993
Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells.
    American journal of physiology. Cell physiology, 2007, Volume: 293, Issue:2

    Topics: Animals; Cationic Amino Acid Transporter 1; Cell Line; Dose-Response Relationship, Drug; Eflornithine; Enzyme Inhibitors; Epithelial Cells; Humans; Large Neutral Amino Acid-Transporter 1; Ornithine; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Ornithine-Oxo-Acid Transaminase; Pigment Epithelium of Eye; Proto-Oncogene Proteins c-myc; Putrescine; RNA Interference; RNA, Messenger; RNA, Small Interfering; Spermidine; Spermine; Swine; Telomerase; Time Factors; Transfection; Up-Regulation

2007