5-fluorodihydrouracil has been researched along with floxuridine in 5 studies
| Studies (5-fluorodihydrouracil) | Trials (5-fluorodihydrouracil) | Recent Studies (post-2010) (5-fluorodihydrouracil) | Studies (floxuridine) | Trials (floxuridine) | Recent Studies (post-2010) (floxuridine) |
|---|---|---|---|---|---|
| 44 | 3 | 6 | 3,556 | 323 | 280 |
| Protein | Taxonomy | 5-fluorodihydrouracil (IC50) | floxuridine (IC50) |
|---|---|---|---|
| Thymidylate synthase | Mus musculus (house mouse) | 1.0862 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Bruijn, EA; Pinedo, HM; Reeuwijk, HJ; Tjaden, UR; van Oosterom, AT | 1 |
| Fosså, SD; Heier, MS; Heintz, R | 1 |
| Canaparo, R; Casale, F; Costa, M; Eandi, M; Fornari, G; Mairone, L; Muntoni, E; Pepa, CD; Serpe, L; Zara, GP | 1 |
| Ciccolini, J; Etienne-Grimaldi, MC; Fischel, JL; Formento, P; Milano, G | 1 |
| Beijnen, JH; Rosing, H; Schellens, JH; Vainchtein, LD | 1 |
1 trial(s) available for 5-fluorodihydrouracil and floxuridine
| Article | Year |
|---|---|
Plasma concentrations of 5-fluorouracil and its metabolites in colon cancer patients.
Topics: Adult; Aged; Area Under Curve; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Administration Schedule; Drug Evaluation; Female; Floxuridine; Fluorouracil; Humans; Infusions, Intravenous; Injections, Intravenous; Kinetics; Leucovorin; Male; Middle Aged; Uridine | 2004 |
4 other study(ies) available for 5-fluorodihydrouracil and floxuridine
| Article | Year |
|---|---|
Pharmacology of 5'-deoxy-5-fluorouridine in patients with resistant ovarian cancer.
Topics: Adult; Aged; Antineoplastic Agents; Female; Floxuridine; Fluorouracil; Humans; Kinetics; Middle Aged; Ovarian Neoplasms | 1985 |
Passage of 5'-dFUrd and its metabolites 5-FU and 5-FUH2 to CSF in a clinical phase 1 study.
Topics: Adult; Aged; Drug Evaluation; Female; Floxuridine; Fluorouracil; Humans; Kinetics; Male; Middle Aged | 1986 |
Lack of contribution of dihydrofluorouracil and alpha-fluoro-beta-alanine to the cytotoxicity of 5'-deoxy-5-fluorouridine on human keratinocytes.
Topics: Antineoplastic Agents; beta-Alanine; Cell Line, Tumor; Dihydrouracil Dehydrogenase (NADP); Dose-Response Relationship, Drug; Floxuridine; Fluorouracil; Foot Dermatoses; Hand Dermatoses; Humans; Inhibitory Concentration 50; Keratinocytes; Syndrome; Thymidine Phosphorylase | 2004 |
A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma.
Topics: 1-Propanol; Acetonitriles; Antimetabolites, Antineoplastic; Capecitabine; Chemical Precipitation; Chromatography, High Pressure Liquid; Deoxycytidine; Drug Stability; Floxuridine; Fluorouracil; Furans; Humans; Linear Models; Pyrimidines; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Trichloroacetic Acid; Uracil; Vidarabine | 2010 |