5-ethynyl-1-ribofuranosylimidazole-4-carboxamide has been researched along with ribavirin in 14 studies
| Studies (5-ethynyl-1-ribofuranosylimidazole-4-carboxamide) | Trials (5-ethynyl-1-ribofuranosylimidazole-4-carboxamide) | Recent Studies (post-2010) (5-ethynyl-1-ribofuranosylimidazole-4-carboxamide) | Studies (ribavirin) | Trials (ribavirin) | Recent Studies (post-2010) (ribavirin) |
|---|---|---|---|---|---|
| 21 | 0 | 2 | 12,316 | 1,880 | 5,443 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (50.00) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baba, M; Honzumi, K; Ito, M; Matsuda, A; Mori, S; Nakamura, K; Numazaki, Y; Obara, T; Oshitani, H; Shigeta, S | 1 |
| Balzarini, J; De Clercq, E; Lee, CK; Schols, D | 1 |
| Andrei, G; Balzarini, J; Cools, M; De Clercq, E; Hosoya, M; Matsuda, A; Minakawa, N; Shigeta, S; Snoeck, R; Ueda, T | 1 |
| Balzarini, J; Bohman, C; De Clercq, E; Fridland, A; Herdewijn, P; Horská, K; Karlsson, A; Van Aerschot, A; Votruba, I; Wang, L | 1 |
| De Clercq, E; González, M; Jashés, M; López-Lastra, M; Sandino, A | 1 |
| Mori, S; Shigeta, S; Watanabe, W | 1 |
| Matsuda, A; Minakawa, N | 1 |
| De Clercq, E; Gilbert, BE; Guzman, E; Matsuda, A; Minakawa, N; Moore-Poveda, DK; Neyts, J; Wyde, PR | 1 |
| Shigeta, S | 1 |
| Balzarini, J; De Clercq, E; Leyssen, P; Neyts, J | 1 |
| Peng, L; Qu, F; Wan, J; Wu, Q; Xia, Y | 1 |
| Bailey, K; Barnard, DL; Carson, DA; Cottam, HB; Day, CW; Heiner, M; Hoopes, J; Lauridsen, L; Lee, J; Li, JK; Montgomery, R; Sidwell, RW; Winslow, S | 1 |
| Battilani, M; Dal Pozzo, F; Galligioni, V; Gallina, L; Scagliarini, A; Vaccari, F | 1 |
| Günther, S; Neyts, J; Ölschläger, S | 1 |
1 review(s) available for 5-ethynyl-1-ribofuranosylimidazole-4-carboxamide and ribavirin
| Article | Year |
|---|---|
Recent progress in antiviral chemotherapy for respiratory syncytial virus infections.
Topics: Amides; Animals; Antibodies, Monoclonal; Antiviral Agents; Biopolymers; Bridged-Ring Compounds; Catechin; Drugs, Investigational; Heterocyclic Compounds; Humans; Immunoglobulins, Intravenous; Lipids; N-Acetylneuraminic Acid; Norbornanes; Oligodeoxyribonucleotides, Antisense; Pyrazoles; Respiratory Syncytial Virus Infections; Respiratory Syncytial Viruses; Ribavirin; Ribonucleosides; Ribose; Risk Factors; Thiocarbamates; Thiones | 2000 |
13 other study(ies) available for 5-ethynyl-1-ribofuranosylimidazole-4-carboxamide and ribavirin
| Article | Year |
|---|---|
Antiviral activities of ribavirin, 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide, and 6'-(R)-6'-C-methylneplanocin A against several ortho- and paramyxoviruses.
Topics: Adenosine; Animals; Antiviral Agents; Cell Survival; Cells, Cultured; HeLa Cells; Humans; Orthomyxoviridae; Paramyxoviridae; Ribavirin; Ribonucleosides; Vero Cells | 1992 |
1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (ribavirin) and 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) markedly potentiate the inhibitory effect of 2',3'-dideoxyinosine on human immunodeficiency virus in peripheral blood lymph
Topics: Antiviral Agents; Cells, Cultured; Didanosine; Drug Synergism; Guanosine Diphosphate; Guanosine Monophosphate; Guanosine Triphosphate; HIV-1; Humans; Inosine Monophosphate; Kinetics; Lymphocytes; Ribavirin; Ribonucleosides | 1991 |
Antiviral activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4- carboxamide and related compounds.
Topics: Adenosylhomocysteinase; Animals; Antimetabolites; Antiviral Agents; Cell Line; Cell Survival; DNA, Viral; Hydrolases; Mice; Ribavirin; Ribonucleosides; RNA, Viral; Tail; Vaccinia virus; Viral Proteins; Virus Diseases; Viruses | 1991 |
Eicar (5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide). A novel potent inhibitor of inosinate dehydrogenase activity and guanylate biosynthesis.
Topics: Adenosine; Animals; Antineoplastic Agents; Cell Division; Deoxyguanine Nucleotides; Guanine; Guanosine; Guanosine Triphosphate; Humans; IMP Dehydrogenase; Leukemia L1210; Lymphocytes; Mice; Mycophenolic Acid; Purine Nucleotides; Ribavirin; Ribonucleosides; Ribonucleotides; Tumor Cells, Cultured | 1993 |
Inhibitors of infectious pancreatic necrosis virus (IPNV) replication.
Topics: Adenosine; Adenosylhomocysteinase; Amides; Animals; Antiviral Agents; Cell Line; DNA; Foscarnet; Hydrolases; IMP Dehydrogenase; Infectious pancreatic necrosis virus; Orotidine-5'-Phosphate Decarboxylase; Pyrazoles; Ribavirin; Ribonucleosides; Ribose; Salmon; Viral Plaque Assay; Virus Replication | 1996 |
A colorimetric LDH assay for the titration of infectivity and the evaluation of anti-viral activity against ortho- and paramyxoviruses.
Topics: Antiviral Agents; Colorimetry; Cytopathogenic Effect, Viral; Humans; L-Lactate Dehydrogenase; Melanoma, Experimental; Orthomyxoviridae; Paramyxoviridae; Ribavirin; Ribonucleosides; Tetrazolium Salts; Thiazoles; Tumor Cells, Cultured; Viral Plaque Assay | 1995 |
Mechanism-based design of inosine 5-monophosphate dehydrogenase inhibitors: synthesis and biological activities of 5-ethynyl-1-beta-D-ribofuranosylimidazole-4-carboxamide (EICAR) and its derivatives.
Topics: Animals; Antineoplastic Agents; Catalysis; Drug Design; Fluorouracil; Humans; IMP Dehydrogenase; Inhibitory Concentration 50; Leukemia L1210; Models, Chemical; Ribavirin; Ribonucleosides; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Use of cotton rats to evaluate the efficacy of antivirals in treatment of measles virus infections.
Topics: Animals; Antiviral Agents; Disease Models, Animal; Measles; Measles virus; Mice; Microbial Sensitivity Tests; Polymers; Rats; Ribavirin; Ribonucleosides; Sigmodontinae; Sulfonic Acids; Tumor Cells, Cultured | 2000 |
The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Guanosine Triphosphate; IMP Dehydrogenase; Microbial Sensitivity Tests; Mycophenolic Acid; Parainfluenza Virus 3, Human; Ribavirin; Ribonucleosides; Vero Cells; Virus Replication; Yellow fever virus | 2005 |
Photolabeling probes of ribavirin and EICAR.
Topics: Antiviral Agents; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Hepacivirus; Hepatitis C; Humans; Imidazoles; Light; Models, Chemical; Models, Molecular; Molecular Biology; Nucleosides; Photoaffinity Labels; Photolysis; Ribavirin; Ribonucleosides; Severe Acute Respiratory Syndrome; Time Factors; Triazoles | 2005 |
Enhancement of the infectivity of SARS-CoV in BALB/c mice by IMP dehydrogenase inhibitors, including ribavirin.
Topics: Animals; Antiviral Agents; Caco-2 Cells; Cell Survival; Chlorocebus aethiops; Cytokines; Cytopathogenic Effect, Viral; Female; Humans; IMP Dehydrogenase; Lung; Mice; Mice, Inbred BALB C; Mycophenolic Acid; Oligonucleotide Array Sequence Analysis; Ribavirin; Ribonucleosides; Severe Acute Respiratory Syndrome; Severe acute respiratory syndrome-related coronavirus; Specific Pathogen-Free Organisms; Vero Cells; Virus Replication | 2006 |
Antiviral efficacy of EICAR against canine distemper virus (CDV) in vitro.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Distemper Virus, Canine; Dose-Response Relationship, Drug; Ribavirin; Ribonucleosides; Vero Cells | 2010 |
Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus.
Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Ebolavirus; Guanosine; Guanosine Triphosphate; IMP Dehydrogenase; Lassa virus; Mycophenolic Acid; Ribavirin; Ribonucleosides; Vero Cells; Virus Replication | 2011 |