5-enolpyruvoylshikimate-3-phosphate and shikimic acid

5-enolpyruvoylshikimate-3-phosphate has been researched along with shikimic acid in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.03)18.7374
1990's15 (45.45)18.2507
2000's9 (27.27)29.6817
2010's7 (21.21)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Huynh, QK1
Griffin, AM; Griffin, HG1
Anderson, KS; Johnson, KA1
Anderson, KS; Benesi, AJ; Johnson, KA; Leo, GC; Sammons, RD; Sikorski, JA1
Coggins, JR; Hawkes, TR; Lewis, T; Lowe, DJ; Mousdale, DM; Thorneley, RN1
Anderson, KS; Johnson, KA; Sikorski, JA1
Abell, C; Balasubramanian, S; Coggins, JR1
Abell, C; Balasubramanian, S; Bornemann, S; Coggins, JR; Lowe, DJ; Thorneley, RN1
Bartlett, PA; Lauhon, CT1
Gruys, KJ; Marzabadi, MR; Pansegrau, PD; Sikorski, JA1
Beusen, DD; Klug, CA; McDowell, LM; Schaefer, J1
Bornemann, S; Lowe, DJ; Macheroux, P; Petersen, J; Thorneley, RN1
Bornemann, S; Ghisla, S; Macheroux, P; Thorneley, RN1
Espe, MP; Klug, CA; McDowell, LM; Schaefer, J; Studelska, DR1
Bornemann, S; Koch, MH; Macheroux, P; Schönbrunn, E; Svergun, DI; Thorneley, RN; Volkov, VV1
Amrhein, N; Krekel, F; Macheroux, P; Oecking, C1
Abell, C; Bornemann, S; Osborne, A; Thorneley, RN1
Du, W; Payne, DJ; Wallis, NG1
Basso, LA; Oliveira, JS; Pinto, CA; Santos, DS1
Amrhein, N; Kitzing, K; Macheroux, P1
An, M; Bartlett, PA; Maitra, U; Neidlein, U1
McDowell, LM; O'Connor, RD; Poliks, B; Schaefer, J; Studelska, DR1
An, M; Bartlett, PA1
Berti, PJ; Clark, ME1
Bornemann, S; Ehammer, H; Macheroux, P; Rauch, G1
Caetano, MS; da Cunha, EF; Freitas, MP; Ramalho, TC1
Cai, XX; Lu, BR; Si, HJ; Snow, AA; Su, J; Wang, F; Wang, W; Xia, H; Xu, T; Yang, X1
Ammann, K; Burgos, NR; Fischer, AJ; Giddings, LV; Gressel, J; Lawton-Rauh, A; Leaver, CJ; Merotto, A; Moses, V; Neal Stewart, C; Streibig, JC; Trewavas, A1
Lu, BR; Snow, AA; Wang, W; Yang, X2
Bury, J; Grunewald, W1
Lin, Y; Liu, Z; Shao, Z; Yi, L; Zhang, L; Zhang, Y1
Dyer, AT; Jha, P; Kumar, V; Lim, CA1

Other Studies

33 other study(ies) available for 5-enolpyruvoylshikimate-3-phosphate and shikimic acid

ArticleYear
5-Enolpyruvylshikimate-3-phosphate synthase from Escherichia coli--the substrate analogue bromopyruvate inactivates the enzyme by modifying Cys-408 and Lys-411.
    Archives of biochemistry and biophysics, 1991, Feb-01, Volume: 284, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Cysteine; Enzyme Activation; Escherichia coli; Hydrolysis; Kinetics; Ligands; Lysine; Molecular Sequence Data; Pyruvates; Shikimic Acid; Substrate Specificity; Transferases; Trypsin

1991
Cloning and DNA sequence analysis of the serC-aroA operon from Salmonella gallinarum; evolutionary relationships between the prokaryotic and eukaryotic aroA-encoded enzymes.
    Journal of general microbiology, 1991, Volume: 137, Issue:1

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Biological Evolution; Cloning, Molecular; DNA; Electronic Data Processing; Escherichia coli; Fungi; Genes, Bacterial; Genetic Complementation Test; Molecular Sequence Data; Operon; Plants; Salmonella; Sequence Homology, Nucleic Acid; Shikimic Acid; Transferases

1991
"Kinetic competence" of the 5-enolpyruvoylshikimate-3-phosphate synthase tetrahedral intermediate.
    The Journal of biological chemistry, 1990, Apr-05, Volume: 265, Issue:10

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Drug Stability; Escherichia coli; Half-Life; Hydrogen-Ion Concentration; Kinetics; Molecular Structure; Phosphates; Phosphoenolpyruvate; Protein Binding; Shikimic Acid; Thermodynamics; Transferases

1990
Observation by 13C NMR of the EPSP synthase tetrahedral intermediate bound to the enzyme active site.
    Biochemistry, 1990, Feb-13, Volume: 29, Issue:6

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Molecular Structure; Phosphoenolpyruvate; Shikimic Acid; Transferases

1990
Chorismate synthase. Pre-steady-state kinetics of phosphate release from 5-enolpyruvylshikimate 3-phosphate.
    The Biochemical journal, 1990, Feb-01, Volume: 265, Issue:3

    Topics: Binding Sites; Chemical Phenomena; Chemistry; Escherichia coli; Kinetics; Lyases; Phosphates; Phosphorus-Oxygen Lyases; Shikimic Acid

1990
A tetrahedral intermediate in the EPSP synthase reaction observed by rapid quench kinetics.
    Biochemistry, 1988, Sep-20, Volume: 27, Issue:19

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Catalysis; Chromatography, High Pressure Liquid; Escherichia coli; Kinetics; Molecular Structure; Phosphates; Phosphoenolpyruvate; Shikimic Acid; Transferases

1988
Observation of a secondary tritium isotope effect in the chorismate synthase reaction.
    Biochemistry, 1995, Jan-10, Volume: 34, Issue:1

    Topics: Carbon Radioisotopes; Isotope Labeling; Kinetics; Lyases; Neurospora crassa; Phosphorus-Oxygen Lyases; Shikimic Acid; Tritium

1995
Escherichia coli chorismate synthase: a deuterium kinetic-isotope effect under single-turnover and steady-state conditions shows that a flavin intermediate forms before the C-(6proR)-H bond is cleaved.
    The Biochemical journal, 1995, Feb-01, Volume: 305 ( Pt 3)

    Topics: Binding Sites; Chorismic Acid; Deuterium; Escherichia coli; Flavins; Hydrogen Bonding; Kinetics; Lyases; Phosphorus-Oxygen Lyases; Recombinant Proteins; Shikimic Acid; Spectrophotometry

1995
Substrate analogs as mechanistic probes for the bifunctional chorismate synthase from Neurospora crassa.
    Biochemistry, 1994, Nov-29, Volume: 33, Issue:47

    Topics: Deuterium; Flavins; Hydrogen-Ion Concentration; Kinetics; Lyases; Molecular Structure; Neurospora crassa; Nucleotides; Phosphorus-Oxygen Lyases; Shikimic Acid; Substrate Specificity

1994
Steady-state kinetic evaluation of the reverse reaction for Escherichia coli 5-enolpyruvoylshikimate-3-phosphate synthase.
    Archives of biochemistry and biophysics, 1993, Aug-01, Volume: 304, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Escherichia coli; Glycine; Glyphosate; Models, Biological; Models, Chemical; Organophosphorus Compounds; Phosphates; Shikimic Acid; Transferases

1993
Ligand geometry of the ternary complex of 5-enolpyruvylshikimate-3-phosphate synthase from rotational-echo double-resonance NMR.
    Biochemistry, 1996, Apr-30, Volume: 35, Issue:17

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Glycine; Glyphosate; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Motion; Recombinant Proteins; Shikimic Acid; Transferases

1996
Binding of the oxidized, reduced, and radical flavin species to chorismate synthase. An investigation by spectrophotometry, fluorimetry, and electron paramagnetic resonance and electron nuclear double resonance spectroscopy.
    Biochemistry, 1996, Feb-06, Volume: 35, Issue:5

    Topics: Electron Spin Resonance Spectroscopy; Flavin Mononucleotide; Fluorometry; Free Radicals; Light; Lyases; Magnetic Resonance Spectroscopy; Organophosphorus Compounds; Oxidation-Reduction; Phosphorus-Oxygen Lyases; Shikimic Acid

1996
Studies with flavin analogs provide evidence that a protonated reduced FMN is the substrate-induced transient intermediate in the reaction of Escherichia coli chorismate synthase.
    The Journal of biological chemistry, 1996, Oct-18, Volume: 271, Issue:42

    Topics: Enzyme Inhibitors; Escherichia coli; Flavin Mononucleotide; Lyases; Organophosphorus Compounds; Phosphorus-Oxygen Lyases; Shikimic Acid; Spectrophotometry, Ultraviolet; Stereoisomerism

1996
Slowed enzymatic turnover allows characterization of intermediates by solid-state NMR.
    Biochemistry, 1997, Dec-16, Volume: 36, Issue:50

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Carbon Isotopes; Escherichia coli; Freeze Drying; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Mutagenesis, Site-Directed; Mutation; Phosphoenolpyruvate; Phosphorus Isotopes; Protein Binding; Shikimic Acid; Temperature

1997
Evidence for a major structural change in Escherichia coli chorismate synthase induced by flavin and substrate binding.
    The Biochemical journal, 1998, Oct-15, Volume: 335 ( Pt 2)

    Topics: Circular Dichroism; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Flavin Mononucleotide; Kinetics; Models, Molecular; Oxidation-Reduction; Phosphorus-Oxygen Lyases; Protein Conformation; Protein Denaturation; Scattering, Radiation; Shikimic Acid; Solubility; Spectrometry, Fluorescence; Spectroscopy, Fourier Transform Infrared; Trypsin; Tryptophan; Ultraviolet Rays

1998
Substrate and inhibitor-induced conformational changes in the structurally related enzymes UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate 3-phosphate synthase (EPSPS).
    Biochemistry, 1999, Jul-13, Volume: 38, Issue:28

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Antibodies, Monoclonal; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Escherichia coli; Hydrolysis; Models, Molecular; Peptide Fragments; Precipitin Tests; Protein Conformation; Shikimic Acid; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Substrate Specificity; Trypsin

1999
Studies with substrate and cofactor analogues provide evidence for a radical mechanism in the chorismate synthase reaction.
    The Journal of biological chemistry, 2000, Nov-17, Volume: 275, Issue:46

    Topics: Benzoquinones; Chromatography, High Pressure Liquid; Dithionite; Escherichia coli; Flavin Mononucleotide; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphorus Compounds; Oxidation-Reduction; Phosphorus-Oxygen Lyases; Recombinant Proteins; Shikimic Acid; Spectrophotometry

2000
The kinetic mechanism of 5-enolpyruvylshikimate-3-phosphate synthase from a gram-positive pathogen Streptococcus pneumoniae.
    Journal of enzyme inhibition, 2000, Volume: 15, Issue:6

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Enzyme Inhibitors; Glycine; Glyphosate; Gram-Positive Bacteria; Kinetics; Phosphates; Phosphoenolpyruvate; Shikimic Acid; Streptococcus pneumoniae

2000
Cloning and overexpression in soluble form of functional shikimate kinase and 5-enolpyruvylshikimate 3-phosphate synthase enzymes from Mycobacterium tuberculosis.
    Protein expression and purification, 2001, Volume: 22, Issue:3

    Topics: Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Mycobacterium tuberculosis; Phosphotransferases (Alcohol Group Acceptor); Recombinant Proteins; Shikimic Acid

2001
Spectroscopic and kinetic characterization of the bifunctional chorismate synthase from Neurospora crassa: evidence for a common binding site for 5-enolpyruvylshikimate 3-phosphate and NADPH.
    The Journal of biological chemistry, 2001, Nov-16, Volume: 276, Issue:46

    Topics: Binding Sites; Cloning, Molecular; DNA, Complementary; Escherichia coli; Flavin Mononucleotide; Kinetics; Models, Chemical; Mutagenesis, Site-Directed; NADP; Neurospora crassa; Oxidoreductases; Oxygen; Phosphorus-Oxygen Lyases; Plasmids; Protein Binding; Protein Structure, Tertiary; Shikimic Acid; Spectrometry, Fluorescence; Spectrophotometry; Substrate Specificity; Time Factors; Ultraviolet Rays

2001
5-enolpyruvylshikimate 3-phosphate synthase: chemical synthesis of the tetrahedral intermediate and assignment of the stereochemical course of the enzymatic reaction.
    Journal of the American Chemical Society, 2003, Oct-22, Volume: 125, Issue:42

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Binding Sites; Models, Molecular; Molecular Conformation; Nuclear Magnetic Resonance, Biomolecular; Shikimic Acid; Stereoisomerism

2003
Characterization of the complex of a trifluoromethyl-substituted shikimate-based bisubstrate inhibitor and 5-enolpyruvylshikimate-3-phosphate synthase by REDOR NMR.
    Biochemistry, 2004, Jun-01, Volume: 43, Issue:21

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Arginine; Enzyme Inhibitors; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Phosphorus Isotopes; Protein Conformation; Shikimic Acid

2004
Enzymatic synthesis of a ring-contracted analogue of 5-enolpyruvylshikimate-3-phosphate.
    Organic letters, 2004, Oct-28, Volume: 6, Issue:22

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Alkyl and Aryl Transferases; Catalysis; Cyclopentanes; Isomerism; Models, Chemical; Phosphoenolpyruvate; Phosphotransferases (Alcohol Group Acceptor); Shikimic Acid

2004
Enolpyruvyl activation by enolpyruvylshikimate-3-phosphate synthase.
    Biochemistry, 2007, Feb-20, Volume: 46, Issue:7

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Binding Sites; Catalysis; Cations, Monovalent; Enzyme Activation; Hydrolysis; Hydroxides; Kinetics; Models, Molecular; Potassium Compounds; Shikimic Acid; Solutions; Water

2007
Replacement of two invariant serine residues in chorismate synthase provides evidence that a proton relay system is essential for intermediate formation and catalytic activity.
    The FEBS journal, 2008, Volume: 275, Issue:7

    Topics: Alanine; Amino Acid Substitution; Catalysis; Flavin Mononucleotide; Flavins; Histidine; Hydrogen Bonding; Mutagenesis, Site-Directed; Neurospora crassa; Phosphorus-Oxygen Lyases; Protein Binding; Protons; Serine; Shikimic Acid; Substrate Specificity

2008
Construction and assessment of reaction models of Class I EPSP synthase. Part II: investigation of the EPSP ketal.
    Journal of biomolecular structure & dynamics, 2013, Volume: 31, Issue:4

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Biocatalysis; Catalytic Domain; Glycine; Glyphosate; Hydrogen Bonding; Kinetics; Models, Chemical; Molecular Structure; Protein Binding; Protein Structure, Tertiary; Shikimic Acid; Thermodynamics

2013
A novel 5-enolpyruvoylshikimate-3-phosphate (EPSP) synthase transgene for glyphosate resistance stimulates growth and fecundity in weedy rice (Oryza sativa) without herbicide.
    The New phytologist, 2014, Volume: 202, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Crosses, Genetic; Genes, Plant; Genetic Fitness; Germination; Glycine; Glyphosate; Herbicides; Hybridization, Genetic; Oryza; Photosynthesis; Plant Weeds; Plants, Genetically Modified; Seeds; Shikimic Acid; Species Specificity; Transgenes; Tryptophan

2014
Overexpression of epsps transgene in weedy rice: insufficient evidence to support speculations about biosafety.
    The New phytologist, 2014, Volume: 202, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Genetic Fitness; Herbicides; Oryza; Plants, Genetically Modified; Shikimic Acid; Transgenes

2014
Scientific data published by a peer-reviewed journal should be properly interpreted: a reply to the letter by Gressel et al. (2014).
    The New phytologist, 2014, Volume: 202, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Genetic Fitness; Herbicides; Oryza; Plants, Genetically Modified; Shikimic Acid; Transgenes

2014
Comment on 'A novel 5-enolpyruvoylshikimate-3-phosphate (EPSP) synthase transgene for glyphosate resistance stimulates growth and fecundity in weedy rice (Oryza sativa) without herbicide' by Wang et al. (2014).
    The New phytologist, 2014, Volume: 202, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Genetic Fitness; Herbicides; Oryza; Plants, Genetically Modified; Shikimic Acid; Transgenes

2014
Using a single transgenic event to infer fitness effects in crop-weed hybrids: a reply to the Letter by Grunewald & Bury (2014).
    The New phytologist, 2014, Volume: 202, Issue:2

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Genetic Fitness; Herbicides; Oryza; Plants, Genetically Modified; Shikimic Acid; Transgenes

2014
Characterization and site-directed mutagenesis of a novel class II 5-enopyruvylshikimate-3-phosphate (EPSP) synthase from the deep-sea bacterium Alcanivorax sp. L27.
    Enzyme and microbial technology, 2014, Volume: 63

    Topics: 3-Phosphoshikimate 1-Carboxyvinyltransferase; Agrobacterium tumefaciens; Alcanivoraceae; Amino Acid Sequence; Bacterial Proteins; Cloning, Molecular; Cold Temperature; Consensus Sequence; Escherichia coli; Escherichia coli Proteins; Gene Library; Genes, Bacterial; Genetic Vectors; Glycine; Glyphosate; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Phylogeny; Protein Conformation; Recombinant Fusion Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Shikimic Acid

2014
Effect of EPSPS gene copy number and glyphosate selection on fitness of glyphosate-resistant Bassia scoparia in the field.
    Scientific reports, 2021, 08-09, Volume: 11, Issue:1

    Topics: Bassia scoparia; Flowers; Gene Dosage; Glycine; Glyphosate; Herbicide Resistance; Shikimic Acid

2021