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5-chloro-2'-deoxyuridine and bromodeoxyuridine

5-chloro-2'-deoxyuridine has been researched along with bromodeoxyuridine in 37 studies

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-199016 (43.24)18.7374
1990's6 (16.22)18.2507
2000's12 (32.43)29.6817
2010's2 (5.41)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Bhooshan, B; Torrence, PF1
Balzarini, J; Bentrude, WG; Béres, J; De Clercq, E; Otvös, L; Sági, G1
Meyer, RB; Nakayama, C; Saneyoshi, M; Santi, DV; Ueda, T; Wataya, Y1
Bretner, M; Cieśla, J; Dzik, JM; Felczak, K; Gołos, B; Kulikowski, T; Miazga, A; Poznański, J; Rode, W; Zieliński, Z1
Douguet, D; Gasse, C; Huteau, V; Marchal, G; Munier-Lehmann, H; Pochet, S1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Baker, PN; Bradshaw, TK; Burke, DC; Morser, J1
Menon, VV; Rachel, AJ; Sharma, T1
Stobetskiĭ, VI2
Mironova, LL; Stobetskiĭ, VI1
Cortés, F; Morgan, WF; Wolff, S1
Mullenders, LH; Natarajan, AT; van Zeeland, AA; Zwanenburg, TS2
DuFrain, RJ1
Heartlein, MW; O'Neill, JP; Preston, RJ3
DuFrain, RJ; Jennings, CJ; Linkous, S; Lowe, KW; McFee, AF1
O'Neill, JP1
Heartlein, MW; O'Neill, JP; Pal, BC; Preston, RJ1
DuFrain, RJ; Garrand, TJ1
Chebotarev, AN; Kuleshov, NP; Samochatova, EV; Stobetskiĭ, VI1
Barendsen, GW; Franken, NA; Kipp, JB; Van Bree, CV1
Ansorge, W; Cremer, T; Fischer, R; Saffrich, R; Stelzer, EH; Trendelenburg, MF; Zink, D1
Chebotarev, AN; Kuleshov, NP; Kuzina, NIu; Stobetskiĭ, VI1
Barone, TA; Maslov, AY; Plunkett, RJ; Pruitt, SC1
Ding, X; Ma, N; Nagahama, M; Semba, R; Yamada, K1
Conboy, MJ; Karasov, AO; Rando, TA1
Kimoto, M; Kishino, M; Ogawa, Y; Toyosawa, S; Yura, Y1
Biggiogera, M; Fakan, S; Solimando, L; Vecchio, L1
Gilbert, DM; Yokochi, T1
Barnard, DL; Humphreys, DE; Hurst, BL; Smee, DF1
Bonaguidi, MA; Czeisler, C; Falciglia, G; Gobeske, KT; Kessler, JA; McGuire, T; Peng, CY1
Imai, M; Kobayashi, K; Mochizuki, H; Mori, K; Murata, K; Nakanishi, S; Nihira, T; Pastan, I; Watanabe, D; Yamada, S; Yamaguchi, M1
Anda, S; Boye, E; Grallert, B1
Belousov, VV; Enikolopov, GN; Maltsev, DI; Mellanson, KA; Podgorny, OV1

Other Studies

37 other study(ies) available for 5-chloro-2'-deoxyuridine and bromodeoxyuridine

ArticleYear
Improved synthesis and in vitro antiviral activities of 5-cyanouridine and 5-cyano-2'-deoxyuridine.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:7

    Topics: Animals; Antiviral Agents; Cell Line; Cytopathogenic Effect, Viral; Deoxyuridine; Humans; Rabbits; Simplexvirus; Uridine; Vaccinia virus

1977
Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.
    Journal of medicinal chemistry, 1986, Volume: 29, Issue:7

    Topics: Animals; Antineoplastic Agents; Antiviral Agents; Cell Line; Deoxyuracil Nucleotides; Drug Evaluation, Preclinical; Humans; Hydrocarbons, Halogenated; Indicators and Reagents; Leukemia L1210; Magnetic Resonance Spectroscopy; Mice; Simplexvirus; Structure-Activity Relationship; Vaccinia virus; Vesicular stomatitis Indiana virus

1986
Thymidine phosphorylase. Substrate specificity for 5-substituted 2'-deoxyuridines.
    Journal of medicinal chemistry, 1980, Volume: 23, Issue:8

    Topics: Animals; Deoxyuridine; Horses; In Vitro Techniques; Models, Biological; Pentosyltransferases; Spectrophotometry, Ultraviolet; Structure-Activity Relationship; Substrate Specificity; Thymidine Phosphorylase

1980
5-Substituted N(4)-hydroxy-2'-deoxycytidines and their 5'-monophosphates: synthesis, conformation, interaction with tumor thymidylate synthase, and in vitro antitumor activity.
    Journal of medicinal chemistry, 2000, Nov-30, Volume: 43, Issue:24

    Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Catalysis; Cell Division; Deoxycytidine; Deoxycytidine Monophosphate; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Idoxuridine; Kinetics; Mice; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; Thymidylate Synthase; Tumor Cells, Cultured

2000
Substituted benzyl-pyrimidines targeting thymidine monophosphate kinase of Mycobacterium tuberculosis: synthesis and in vitro anti-mycobacterial activity.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Antitubercular Agents; Chlorocebus aethiops; Drug Delivery Systems; Drug Design; Humans; Mycobacterium bovis; Mycobacterium tuberculosis; Nucleoside-Phosphate Kinase; Pyrimidines; Vero Cells

2008
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
The effect of 5-bromodeoxyuridine on interferon production in human cells.
    The Journal of general virology, 1979, Volume: 45, Issue:1

    Topics: Bromodeoxyuridine; Cell Division; Cell Line; Deoxycytidine; Deoxyuridine; DNA; Floxuridine; Humans; Idoxuridine; Interferons; Thymidine

1979
Harlequin banding and localisation of sister-chromatid exchanges.
    Mutation research, 1991, Volume: 264, Issue:2

    Topics: Animals; Bromodeoxyuridine; Chromosome Banding; Deer; Deoxyuridine; In Vitro Techniques; Metaphase; Mitomycin; Sister Chromatid Exchange

1991
[Telomeric chromosome fusion in cells with micronuclei under the combined action of hyperthermia and hypothermia and halogenated analogs of thymidine].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:7

    Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Deoxyuridine; Idoxuridine; Micronuclei, Chromosome-Defective; Telomere; Temperature; Thymidine

1991
[5-Chlorodeoxyuridine, more effectively than 5-bromodeoxyuridine, induces the formation of specific dicentric chromosomes in cells with micronuclei].
    Tsitologiia, 1988, Volume: 30, Issue:12

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; Demecolcine; Deoxyuridine; Micronucleus Tests; Molecular Weight

1988
Effect of exogenous thymidine on sister-chromatid exchange frequency in Chinese hamster ovary cells with bromodeoxyuridine- and chlorodeoxyuridine-substituted chromosomes.
    Mutation research, 1987, Volume: 192, Issue:4

    Topics: Animals; Bromodeoxyuridine; Cell Cycle; Cell Line; Cricetinae; Cricetulus; Deoxyuridine; Sister Chromatid Exchange; Thymidine

1987
DNA lesions, chromosomal aberrations and G2 delay in CHO cells cultured in medium containing bromo- or chloro-deoxyuridine.
    Mutation research, 1984, Volume: 127, Issue:2

    Topics: Animals; Benzamides; Bromodeoxyuridine; Caffeine; Cell Survival; Chromosome Aberrations; Cricetinae; Cricetulus; Deoxyuridine; DNA Repair; DNA, Single-Stranded; Female; Flow Cytometry; Hydroxyurea; Interphase; Ovary; Poly(ADP-ribose) Polymerases

1984
Induction of DNA lesions, chromosomal aberrations, and G2 delay by bromo- and chlorodeoxyuridine.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Animals; Bromodeoxyuridine; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Deoxyuridine; DNA; Female; Fibroblasts; Humans; Interphase; Leukemia L5178; Mice; Ovary; Poly(ADP-ribose) Polymerases; Skin

1984
Probing sister chromatid exchange formation with halogenated pyrimidines.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Animals; Bone Marrow; Bromodeoxycytidine; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Humans; Idoxuridine; Lymphocytes; Mice; Models, Genetic; Pyrimidines; Rabbits; Sister Chromatid Exchange

1984
The replication of unsubstituted and 5-bromodeoxyuridine- or 5-chlorodeoxyuridine-substituted DNA regulates the rate of induction of sister chromatid exchanges.
    Basic life sciences, 1984, Volume: 29 Pt A

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Deoxyuridine; DNA Replication; Female; Fibroblasts; Ovary; Sister Chromatid Exchange; Templates, Genetic

1984
Sister-chromatid exchanges and gene mutations are induced by the replication of 5-bromo- and 5-chloro-deoxyuridine substituted DNA.
    Mutation research, 1983, Volume: 109, Issue:2

    Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxyuridine; DNA Replication; Female; Mutation; Ovary; Sister Chromatid Exchange

1983
In vivo SCE analysis using bromodeoxyuridine, iododeoxyuridine, and chlorodeoxyuridine.
    Mutation research, 1984, Volume: 139, Issue:2

    Topics: Animals; Bone Marrow Cells; Bromodeoxyuridine; Crossing Over, Genetic; Deoxyuridine; Idoxuridine; Mice; Rabbits; Sister Chromatid Exchange

1984
Quantification of the induction of SCE due to the replication of unsubstituted and BrdU- or CldU-substituted DNA in CHO cells.
    Mutation research, 1984, Volume: 140, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cells, Cultured; Cricetinae; Crossing Over, Genetic; Deoxyuridine; DNA Replication; Female; Ovary; Sister Chromatid Exchange

1984
SCE induction is proportional to substitution in DNA for thymidine by CldU and BrdU.
    Mutation research, 1983, Volume: 107, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Line; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxyuridine; DNA; Female; Kinetics; Ovary; Sister Chromatid Exchange; Thymidine

1983
The induction of specific-locus mutations and sister-chromatid exchanges by 5-bromo- and 5-chloro-deoxyuridine.
    Mutation research, 1982, Feb-22, Volume: 92, Issue:1-2

    Topics: Animals; Bromodeoxyuridine; Cell Line; Chromosome Mapping; Chromosomes; Cricetinae; Cricetulus; Crossing Over, Genetic; Deoxyuridine; Drug Resistance; Female; Mutagens; Mutation; Ovary; Sister Chromatid Exchange; Thioguanine

1982
The influence of incorporated halogenated analogues of thymidine on the sister-chromatid exchange frequency in human lymphocytes.
    Mutation research, 1981, Volume: 91, Issue:3

    Topics: Bromodeoxyuridine; Cell Division; Cells, Cultured; Crossing Over, Genetic; Deoxyuridine; Female; Humans; Idoxuridine; Lymphocytes; Male; Sister Chromatid Exchange; Structure-Activity Relationship

1981
[Cytogenetic anomalies in cultured human lymphocytes exposed to halogen analogs of thymidine].
    Biulleten' eksperimental'noi biologii i meditsiny, 1995, Volume: 120, Issue:9

    Topics: Adult; Bromodeoxyuridine; Cells, Cultured; Chromosome Aberrations; Deoxyuridine; Female; Humans; Idoxuridine; Lymphocytes; Male; Mutagens

1995
[Halogenated analogs of thymidine increase the level of chromosome aberrations in patients with Fanconi's anemia].
    Biulleten' eksperimental'noi biologii i meditsiny, 1996, Volume: 121, Issue:4

    Topics: Adolescent; Bromodeoxyuridine; Chromosome Aberrations; Deoxyuridine; Fanconi Anemia; Humans; In Vitro Techniques; Male; Mutagens

1996
Modification of potentially lethal damage in irradiated Chinese hamster V79 cells after incorporation of halogenated pyrimidines.
    International journal of radiation biology, 1997, Volume: 72, Issue:1

    Topics: Animals; Bromodeoxyuridine; Cell Division; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Deoxyuridine; DNA; Dose-Response Relationship, Radiation; Fibroblasts; Idoxuridine; Radiation Injuries, Experimental; Radiation Tolerance; Radiation-Sensitizing Agents

1997
Structure and dynamics of human interphase chromosome territories in vivo.
    Human genetics, 1998, Volume: 102, Issue:2

    Topics: Bromodeoxyuridine; Carbocyanines; Cell Nucleus; Chromosome Mapping; Chromosomes, Human; Deoxyuracil Nucleotides; Deoxyuridine; DNA Replication; Fibroblasts; Fluorescent Dyes; HeLa Cells; Humans; Idoxuridine; Interphase; Microscopy, Fluorescence; Neuroblastoma; Thymidine; Tumor Cells, Cultured

1998
[Chromosomal abnormalities in lymphocytes from a patient with Werner's syndrome in intact culture and after treatment with halogenated analogs of thymidine].
    Tsitologiia, 2002, Volume: 44, Issue:1

    Topics: Adult; Bromodeoxyuridine; Chromosome Aberrations; Chromosomes, Human, Pair 11; Chromosomes, Human, Pair 15; Deoxyuridine; Humans; Idoxuridine; Lymphocytes; Male; Nucleic Acid Synthesis Inhibitors; Werner Syndrome

2002
Neural stem cell detection, characterization, and age-related changes in the subventricular zone of mice.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Feb-18, Volume: 24, Issue:7

    Topics: Administration, Oral; Aging; Animals; Antigens, Differentiation; Bromodeoxyuridine; Cell Count; Cell Cycle; Cell Division; Cells, Cultured; Cytarabine; Deoxyuridine; Glial Fibrillary Acidic Protein; Idoxuridine; Intermediate Filament Proteins; Lateral Ventricles; Male; Mice; Minichromosome Maintenance Complex Component 2; Nerve Tissue Proteins; Nestin; Neurons; Nuclear Proteins; Stem Cells

2004
Discrimination of cell nuclei in early S-phase, mid-to-late S-phase, and G(2)/M-phase by sequential administration of 5-bromo-2'-deoxyuridine and 5-chloro-2'-deoxyuridine.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2005, Volume: 53, Issue:11

    Topics: Animals; Bromodeoxyuridine; Cell Nucleus; Cells, Cultured; Deoxyuridine; DNA Replication; G2 Phase; Immunohistochemistry; Indicators and Reagents; Intestine, Small; Male; Mice; S Phase

2005
High incidence of non-random template strand segregation and asymmetric fate determination in dividing stem cells and their progeny.
    PLoS biology, 2007, Volume: 5, Issue:5

    Topics: Animals; Bromodeoxyuridine; Cell Differentiation; Cell Division; Chromosome Segregation; Deoxyuridine; DNA Replication; Idoxuridine; Mice; Muscles; Rats; Regeneration; Satellite Cells, Skeletal Muscle; Stem Cells

2007
Label-retaining cells in the rat submandibular gland.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2008, Volume: 56, Issue:1

    Topics: Actins; Animals; Biomarkers; Bromodeoxyuridine; Cell Count; Cell Lineage; Deoxyuridine; Fluorescent Dyes; Idoxuridine; Immunohistochemistry; Keratin-18; Rats; Rats, Wistar; Regeneration; Stem Cells; Submandibular Gland

2008
Use of halogenated precursors for simultaneous DNA and RNA detection by means of immunoelectron and immunofluorescence microscopy.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2008, Volume: 56, Issue:1

    Topics: Animals; Antibodies; Bromodeoxyuridine; CHO Cells; Cricetinae; Cricetulus; Cross Reactions; Deoxyuridine; DNA; Idoxuridine; Microscopy, Fluorescence; Microscopy, Immunoelectron; RNA

2008
Replication labeling with halogenated thymidine analogs.
    Current protocols in cell biology, 2007, Volume: Chapter 22

    Topics: Animals; Bromodeoxyuridine; Deoxyuridine; DNA Replication; Idoxuridine; In Situ Hybridization, Fluorescence; Indicators and Reagents; Mammals; Microscopy, Fluorescence; Replication Origin; S Phase

2007
Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.
    Antiviral chemistry & chemotherapy, 2008, Volume: 19, Issue:1

    Topics: Animals; Antiviral Agents; Bromodeoxyuridine; Cell Line, Tumor; Chlorocebus aethiops; Deoxyuridine; Floxuridine; Humans; Idoxuridine; Mice; Phosphorylation; Thymidine; Thymidine Kinase; Vaccinia; Vaccinia virus; Vero Cells; Viral Plaque Assay

2008
Noggin expands neural stem cells in the adult hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Sep-10, Volume: 28, Issue:37

    Topics: Adult Stem Cells; Analysis of Variance; Animals; Bone Morphogenetic Protein 4; Bone Morphogenetic Proteins; Bromodeoxyuridine; Carrier Proteins; Cell Differentiation; Cells, Cultured; Deoxyuridine; Glial Fibrillary Acidic Protein; Hippocampus; Idoxuridine; Intercellular Signaling Peptides and Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neural Cell Adhesion Molecule L1; Neurofilament Proteins; Nucleic Acid Synthesis Inhibitors; O Antigens; Phosphopyruvate Hydratase; Sialic Acids; Telomerase

2008
Compensation of depleted neuronal subsets by new neurons in a local area of the adult olfactory bulb.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Jul-20, Volume: 31, Issue:29

    Topics: Animals; Animals, Newborn; Bromodeoxyuridine; Calbindin 2; Cell Count; Cell Movement; Cell Transplantation; Cerebral Ventricles; Dendritic Spines; Deoxyuridine; Doublecortin Domain Proteins; Female; Gene Expression Regulation; Glutamate Decarboxylase; Green Fluorescent Proteins; Humans; Idoxuridine; Immunotoxins; In Situ Nick-End Labeling; Interleukin-2 Receptor alpha Subunit; Luminescent Proteins; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microtubule-Associated Proteins; Neurogenesis; Neurons; Neuropeptides; Olfactory Bulb; Receptors, Metabotropic Glutamate; S100 Calcium Binding Protein G; Statistics, Nonparametric; Synapses; Time Factors; Transduction, Genetic; Vesicular Glutamate Transport Protein 1

2011
Cell-cycle analyses using thymidine analogues in fission yeast.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Bromodeoxyuridine; Cell Cycle; Cell Proliferation; Deoxyuridine; DNA Replication; DNA, Fungal; Schizosaccharomyces; Staining and Labeling; Thymidine

2014
The bioavailability time of commonly used thymidine analogues after intraperitoneal delivery in mice: labeling kinetics in vivo and clearance from blood serum.
    Histochemistry and cell biology, 2022, Volume: 157, Issue:2

    Topics: Animals; Biological Availability; Bromodeoxyuridine; Dentate Gyrus; Deoxyuridine; Glyburide; Injections, Intraperitoneal; Kinetics; Mice; Mice, Inbred C57BL; Thymidine

2022