5-chloro-2'-deoxyuridine 5'-triphosphate has been researched along with floxuridine in 1 studies
*Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. [MeSH]
*Floxuridine: An antineoplastic antimetabolite that is metabolized to fluorouracil when administered by rapid injection; when administered by slow, continuous, intra-arterial infusion, it is converted to floxuridine monophosphate. It has been used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract. [MeSH]
| Studies (5-chloro-2'-deoxyuridine 5'-triphosphate) | Trials (5-chloro-2'-deoxyuridine 5'-triphosphate) | Recent Studies (post-2010) (5-chloro-2'-deoxyuridine 5'-triphosphate) | Studies (floxuridine) | Trials (floxuridine) | Recent Studies (post-2010) (floxuridine) |
|---|---|---|---|---|---|
| 5 | 0 | 0 | 3,556 | 323 | 280 |
| Protein | Taxonomy | 5-chloro-2'-deoxyuridine 5'-triphosphate (IC50) | floxuridine (IC50) |
|---|---|---|---|
| Thymidylate synthase | Mus musculus (house mouse) | 1.0862 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bretner, M; Cieśla, J; Dzik, JM; Felczak, K; Gołos, B; Kulikowski, T; Miazga, A; Poznański, J; Rode, W; Zieliński, Z | 1 |
1 other study(ies) available for 5-chloro-2'-deoxyuridine 5'-triphosphate and floxuridine
| Article | Year |
|---|---|
5-Substituted N(4)-hydroxy-2'-deoxycytidines and their 5'-monophosphates: synthesis, conformation, interaction with tumor thymidylate synthase, and in vitro antitumor activity.
Topics: Animals; Antineoplastic Agents; Bromodeoxyuridine; Catalysis; Cell Division; Deoxycytidine; Deoxycytidine Monophosphate; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Idoxuridine; Kinetics; Mice; Molecular Conformation; Stereoisomerism; Structure-Activity Relationship; Thymidylate Synthase; Tumor Cells, Cultured | 2000 |