5-chloro-2'-deoxycytidine has been researched along with deoxycytidine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (35.29) | 18.7374 |
| 1990's | 4 (23.53) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gottlieb, C; Greer, S; Marion, HS; Santos, O; Schwade, J | 1 |
| Boothman, DA; Briggle, TV; Greer, SB; Perez, LM; Santos, O | 1 |
| Davis, MA; Lawrence, TS | 1 |
| Brown, JM; Rice, GC; Russell, KJ | 1 |
| Greer, S; Perez, LM | 1 |
| Briggle, TV; Greer, S; Mekras, JA; Perez, LM | 1 |
| Bagwell, CB; Fox, LM; Greer, SB; Mekras, JA | 1 |
| DuFrain, RJ | 1 |
| Greer, S; Marion, HS; Schwade, J | 1 |
| Byun, J; Heinecke, JW; Henderson, JP | 2 |
| Aller, A; Alvarez, M; Arnold, D; Burk, R; Dauphinée, M; Greer, S; Knapinska, A; Mas, M; Norris, C; Wozniak, C | 1 |
| Bigelow, JC; Hale, JT; Mathews, LA; McCormack, JJ | 1 |
| Badouard, C; Cadet, J; Favier, A; Masuda, M; Nishino, H; Ravanat, JL | 1 |
| Dedon, PC; Fox, JG; Kang, P; Knutson, CG; Korzenik, JR; Liberman, RG; Lu, K; Mangerich, A; Prestwich, EG; Raczynski, AR; Tannenbaum, SR; Wishnok, JS; Wogan, GN; Ye, W; Zeng, Y | 1 |
| Cortese, M; Delporte, C; Dufour, D; Nève, J; Noyon, C; Poelvoorde, P; Roumeguère, T; Rousseau, A; Van Antwerpen, P; Vanhamme, L; Zouaoui Boudjeltia, K | 1 |
| Alcolea Palafox, M; Rastogi, VK; Singh, SP | 1 |
17 other study(ies) available for 5-chloro-2'-deoxycytidine and deoxycytidine
| Article | Year |
|---|---|
5-chlorodeoxycytidine, a radiosensitizer effective against RIF-1 and Lewis lung carcinoma, is also effective against a DMBA-induced mammary adenocarcinoma and the EMT-6 tumor in BALB/c mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adenocarcinoma; Animals; Combined Modality Therapy; Deoxycytidine; Fibrosarcoma; Lung Neoplasms; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Radiation-Sensitizing Agents | 1992 |
Radiation, pool size and incorporation studies in mice with 5-chloro-2'-deoxycytidine.
Topics: Animals; Aspartic Acid; Combined Modality Therapy; Cytidine Deaminase; Deoxycytidine; DNA, Neoplasm; Drug Therapy, Combination; Mice; Mice, Inbred C3H; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Sarcoma, Experimental; Tetrahydrouridine; Uracil; Uridine Phosphorylase | 1990 |
Selective radiosensitization and cytotoxicity of human melanoma cells using halogenated deoxycytidines and tetrahydrouridine.
Topics: Antineoplastic Agents; Bromodeoxycytidine; Cell Line; Deoxycytidine; Fibroblasts; Humans; In Vitro Techniques; Melanoma; Radiation-Sensitizing Agents; Tetrahydrouridine; Tumor Cells, Cultured; Uridine | 1989 |
In vitro and in vivo radiation sensitization by the halogenated pyrimidine 5-chloro-2'-deoxycytidine.
Topics: Animals; Bromodeoxyuridine; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Deoxycytidine; Female; Flow Cytometry; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Radiation-Sensitizing Agents; Tetrahydrouridine | 1986 |
Sensitization to X ray by 5-chloro-2'-deoxycytidine co-administered with tetrahydrouridine in several mammalian cell lines and studies of 2'-chloro derivatives.
Topics: Animals; Bromodeoxyuridine; Cell Line; Cell Survival; Deoxycytidine; Drug Combinations; Humans; In Vitro Techniques; Radiation-Sensitizing Agents; Tetrahydrouridine; Uridine | 1986 |
Marked radiosensitization of cells in culture to X ray by 5-chlorodeoxycytidine coadministered with tetrahydrouridine, and inhibitors of pyrimidine biosynthesis.
Topics: Animals; Aspartic Acid; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Deoxycytidine; Dose-Response Relationship, Radiation; Floxuridine; Humans; Laryngeal Neoplasms; Mice; Organophosphorus Compounds; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Tetrahydrouridine; Uridine | 1984 |
Capacity of deoxycytidine to selectively antagonize cytotoxicity of 5-halogenated analogs of deoxycytidine without loss of antiherpetic activity.
Topics: Animals; Antiviral Agents; Cell Cycle; Cytidine Deaminase; Deoxycytidine; Deoxyuridine; DNA, Viral; Herpes Simplex; Kinetics; Mice; Simplexvirus; Virus Replication | 1982 |
Probing sister chromatid exchange formation with halogenated pyrimidines.
Topics: Animals; Bone Marrow; Bromodeoxycytidine; Bromodeoxyuridine; Deoxycytidine; Deoxyuridine; Humans; Idoxuridine; Lymphocytes; Mice; Models, Genetic; Pyrimidines; Rabbits; Sister Chromatid Exchange | 1984 |
Five-chlorodeoxycytidine and biomodulators of its metabolism result in fifty to eighty percent cures of advanced EMT-6 tumors when used with fractionated radiation.
Topics: Adenocarcinoma; Animals; Aspartic Acid; Body Weight; Deoxycytidine; Idoxuridine; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Phosphonoacetic Acid; Radiation-Sensitizing Agents; Radiotherapy Dosage; Tetrahydrouridine | 1995 |
Chlorination of nucleobases, RNA and DNA by myeloperoxidase: a pathway for cytotoxicity and mutagenesis by activated phagocytes.
Topics: Cytotoxicity, Immunologic; Deoxycytidine; Humans; Mutagenesis; Peroxidase; Phagocytes | 1999 |
Five-chlorodeoxycytidine, a tumor-selective enzyme-driven radiosensitizer, effectively controls five advanced human tumors in nude mice.
Topics: Animals; Breast Neoplasms; Carcinoma, Squamous Cell; Combined Modality Therapy; DCMP Deaminase; Deoxycytidine; Deoxycytidine Kinase; Female; Glioblastoma; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Neoplasm Proteins; Neoplasms; Prostatic Neoplasms; Radiation-Sensitizing Agents; Radiotherapy Dosage; Spinal Cord; Tetrahydrouridine | 2001 |
Analytical and pharmacokinetic studies with 5-chloro-2'-deoxycytidine.
Topics: Animals; Antimetabolites; Deoxycytidine; Drug Stability; Mice; Models, Animal; Tetrahydrouridine; Tissue Distribution | 2002 |
Identification and quantification of mutagenic halogenated cytosines by gas chromatography, fast atom bombardment, and electrospray ionization tandem mass spectrometry.
Topics: Bromodeoxycytidine; Chromatography, Gas; Chromatography, High Pressure Liquid; Cytosine; Deoxycytidine; Halogens; Mutagenesis; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Fast Atom Bombardment; Time Factors | 2003 |
Detection of chlorinated DNA and RNA nucleosides by HPLC coupled to tandem mass spectrometry as potential biomarkers of inflammation.
Topics: Adenine; Biomarkers; Cell Line, Tumor; Chromatography, High Pressure Liquid; Cytosine; Deoxyadenosines; Deoxycytidine; Deoxyguanosine; Guanine; Humans; Inflammation; Leukocytes; Nucleosides; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization | 2005 |
Chemical and cytokine features of innate immunity characterize serum and tissue profiles in inflammatory bowel disease.
Topics: Acute-Phase Proteins; Animals; Biomarkers; Chemokines; Cytokines; Deoxycytidine; Disease Models, Animal; DNA Damage; DNA-Binding Proteins; Female; Helicobacter hepaticus; Helicobacter Infections; Humans; Immunity, Innate; Inflammatory Bowel Diseases; Male; Mice; Mice, Knockout; Tyrosine | 2013 |
Validation of a sensitive LC/MSMS method for chloronucleoside analysis in biological matrixes and its applications.
Topics: Chromatography, Liquid; Deoxycytidine; Guanosine; Peroxidase; Tandem Mass Spectrometry | 2016 |
FT-IR and FT-Raman spectra of 5-chlorocytosine: Solid state simulation and tautomerism. Effect of the chlorine substitution in the Watson-Crick base pair 5-chlorodeoxycytidine-deoxyguanosine.
Topics: Base Pairing; Chlorine; Computer Simulation; Crystallization; Cytosine; Deoxycytidine; Deoxyguanosine; Hydrogen Bonding; Molecular Conformation; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Stereoisomerism; Thermodynamics; Vibration | 2018 |