5-carboxyfluorescein diacetate and terfenadine

5-carboxyfluorescein diacetate has been researched along with terfenadine in 2 studies

Compound Research Comparison

Studies (5-carboxyfluorescein diacetate)	Trials (5-carboxyfluorescein diacetate)	Recent Studies (post-2010) (5-carboxyfluorescein diacetate)	Studies (terfenadine)	Trials (terfenadine)	Recent Studies (post-2010) (terfenadine)
41	0	13	1,751	568	346

Protein Interaction Comparison

Protein	Taxonomy	terfenadine (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1F	Homo sapiens (human)	0.93
5-hydroxytryptamine receptor 4	Cavia porcellus (domestic guinea pig)	1.231
Epidermal growth factor receptor	Homo sapiens (human)	3.566
Tyrosine-protein kinase Fyn	Homo sapiens (human)	6.123
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	2
Aldo-keto reductase family 1 member B1	Rattus norvegicus (Norway rat)	1.928
ATP-dependent translocase ABCB1	Homo sapiens (human)	1.8167
Cytochrome P450 3A4	Homo sapiens (human)	0.32
Muscarinic acetylcholine receptor M1	Homo sapiens (human)	2.9
D(2) dopamine receptor	Homo sapiens (human)	6.167
Dipeptidyl peptidase 4	Rattus norvegicus (Norway rat)	0.35
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	2.34
Alpha-2C adrenergic receptor	Homo sapiens (human)	3.748
D	Rattus norvegicus (Norway rat)	0.1288
Alpha-2B adrenergic receptor	Rattus norvegicus (Norway rat)	0.1288
Substance-K receptor	Homo sapiens (human)	2.677
D(1A) dopamine receptor	Homo sapiens (human)	2.673
Alpha-2C adrenergic receptor	Rattus norvegicus (Norway rat)	0.1288
Alpha-2A adrenergic receptor	Rattus norvegicus (Norway rat)	0.1288
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	2.34
Sodium-dependent noradrenaline transporter	Homo sapiens (human)	1.928
Sodium-dependent dopamine transporter	Rattus norvegicus (Norway rat)	0.1288
Alpha-1D adrenergic receptor	Homo sapiens (human)	2.34
5-hydroxytryptamine receptor 2A	Homo sapiens (human)	0.255
5-hydroxytryptamine receptor 2C	Homo sapiens (human)	1.231
Histamine H1 receptor	Cavia porcellus (domestic guinea pig)	0.094
Alpha-1A adrenergic receptor	Homo sapiens (human)	2.34
Histamine H1 receptor	Homo sapiens (human)	0.0115
Alpha-1B adrenergic receptor	Homo sapiens (human)	2.34
D(3) dopamine receptor	Homo sapiens (human)	1.503
5-hydroxytryptamine receptor 2B	Homo sapiens (human)	0.048
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	2.34
5-hydroxytryptamine receptor 6	Homo sapiens (human)	1.306
Cytochrome P450 2J2	Homo sapiens (human)	8.1
C-C chemokine receptor type 5	Homo sapiens (human)	1.103
Voltage-dependent L-type calcium channel subunit alpha-1D	Homo sapiens (human)	0.93
Sodium-dependent dopamine transporter	Homo sapiens (human)	0.255
Potassium voltage-gated channel subfamily H member 2	Homo sapiens (human)	0.2233
Voltage-dependent L-type calcium channel subunit alpha-1S	Homo sapiens (human)	0.93
Voltage-dependent L-type calcium channel subunit alpha-1C	Homo sapiens (human)	1.125
Sodium channel protein type 5 subunit alpha	Homo sapiens (human)	0.971

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1

Other Studies

2 other study(ies) available for 5-carboxyfluorescein diacetate and terfenadine

Article	Year
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012

Article

Year

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012