Page last updated: 2024-09-04

5-carboxyfluorescein diacetate and saquinavir

5-carboxyfluorescein diacetate has been researched along with saquinavir in 2 studies

Compound Research Comparison

Studies
(5-carboxyfluorescein diacetate)
Trials
(5-carboxyfluorescein diacetate)
Recent Studies (post-2010)
(5-carboxyfluorescein diacetate)
Studies
(saquinavir)
Trials
(saquinavir)
Recent Studies (post-2010) (saquinavir)
410131,454256219

Protein Interaction Comparison

ProteinTaxonomy5-carboxyfluorescein diacetate (IC50)saquinavir (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.9
Bile salt export pumpHomo sapiens (human)3.9
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (BRU ISOLATE)0.016
Gag-Pol polyproteinHuman immunodeficiency virus type 2 (ISOLATE ROD)0.0084
Gag polyproteinHIV-1 M:B_MN0.0131
ATP-dependent translocase ABCB1Homo sapiens (human)4.05
Cytochrome P450 3A4Homo sapiens (human)1.5
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.0066
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4.273
Substance-K receptorHomo sapiens (human)6.214
Thromboxane-A synthase Homo sapiens (human)2.182
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)4.273
Mu-type opioid receptorHomo sapiens (human)9.625
Kappa-type opioid receptorHomo sapiens (human)6.951
Exoribonuclease H Human immunodeficiency virus 20.0005
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.9
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.9
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.9
Genome polyprotein Human rhinovirus sp.0.0005
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)8.26
Protease Human immunodeficiency virus 10.0217
Protease Human immunodeficiency virus 10.0004

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1

Other Studies

2 other study(ies) available for 5-carboxyfluorescein diacetate and saquinavir

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012