5-carboxyfluorescein diacetate and cyclosporine

5-carboxyfluorescein diacetate has been researched along with cyclosporine in 2 studies

Compound Research Comparison

Studies (5-carboxyfluorescein diacetate)	Trials (5-carboxyfluorescein diacetate)	Recent Studies (post-2010) (5-carboxyfluorescein diacetate)	Studies (cyclosporine)	Trials (cyclosporine)	Recent Studies (post-2010) (cyclosporine)
41	0	13	377	2	170

Protein Interaction Comparison

Protein	Taxonomy	cyclosporine (IC50)
ATP-binding cassette sub-family C member 3	Homo sapiens (human)	0.6315
Bile salt export pump	Rattus norvegicus (Norway rat)	0.6
Bile salt export pump	Homo sapiens (human)	3.5
Interleukin-2	Mus musculus (house mouse)	0.005
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	0.7
ATP-dependent translocase ABCB1	Homo sapiens (human)	1.6792
Cytochrome P450 3A4	Homo sapiens (human)	3.734
Replicase polyprotein 1ab	Severe acute respiratory syndrome coronavirus 2	5.82
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Cytochrome P450 3A5	Homo sapiens (human)	2.06
ATP-dependent translocase ABCB1	Mus musculus (house mouse)	4.8
Substance-K receptor	Homo sapiens (human)	4.139
Peptidyl-prolyl cis-trans isomerase B	Homo sapiens (human)	0.0088
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Cytochrome P450 3A7	Homo sapiens (human)	2.06
Cytochrome P450 2C19	Homo sapiens (human)	7
Multidrug resistance-associated protein 1	Homo sapiens (human)	3.5082
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	9.34
Peptidyl-prolyl cis-trans isomerase A	Homo sapiens (human)	0.0252
Peptidyl-prolyl cis-trans isomerase FKBP4	Homo sapiens (human)	0.016
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Homo sapiens (human)	0.183
Peptidyl-prolyl cis-trans isomerase D	Homo sapiens (human)	0.0036
Sodium/bile acid cotransporter	Homo sapiens (human)	1
Reverse transcriptase/RNaseH	Human immunodeficiency virus 1	0.455
Cytochrome P450 3A43	Homo sapiens (human)	2.06
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Mus musculus (house mouse)	0.57
Solute carrier organic anion transporter family member 1B3	Homo sapiens (human)	1.3
Broad substrate specificity ATP-binding cassette transporter ABCG2	Homo sapiens (human)	4.3
Solute carrier organic anion transporter family member 1B1	Homo sapiens (human)	0.95

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1

Other Studies

2 other study(ies) available for 5-carboxyfluorescein diacetate and cyclosporine

Article	Year
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012

Article

Year

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008

Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.

Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012