5-carboxamidotryptamine has been researched along with 5-methoxytryptamine in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (4.88) | 18.7374 |
| 1990's | 28 (68.29) | 18.2507 |
| 2000's | 11 (26.83) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Branchek, TA; Hartig, PR; Macchi, MJ; Weinshank, RL; Zgombick, JM | 1 |
| Hamblin, MW; Metcalf, MA | 1 |
| Glennon, RA | 2 |
| Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP | 1 |
| Adham, N; Bard, JA; Branchek, TA; Vaysse, P; Weinshank, RL; Zgombick, J | 1 |
| Adham, N; Bard, J; Branchek, TA; Durkin, M; Hartig, PR; Kao, HT; Olsen, M; Schecter, LE; Urquhart, D; Weinshank, RL | 1 |
| Hamblin, MW; Jose, PA; Metcalf, MA; Monsma, FJ; Shen, Y; Sibley, DR | 1 |
| Amlaiky, N; Hen, R; Plassat, JL | 1 |
| Arrang, JM; Diaz, J; Leurs, R; Ruat, M; Schwartz, JC; Tardivel-Lacombe, J; Traiffort, E | 1 |
| Audia, JE; Baez, M; Cohen, ML; Kursar, JD; Lucaites, VL; Nelson, DL; Nissen, JS; Schenck, KW; Wainscott, DB | 1 |
| Druck, T; Hamblin, MW; Huebner, K; Khan, N; Kohen, R; Lachowicz, JE; Meltzer, HY; Metcalf, MA; Roth, BL; Sibley, DR | 1 |
| Carrupt, PA; Gaillard, P; Schambel, P; Testa, B | 1 |
| Izzarelli, DG; Lewis-Higgins, L; Palmer, D; Parker, EM; Shapiro, RA | 1 |
| Gommeren, W; Haegeman, G; Heylen, L; Lesage, AS; Leysen, JE; Luyten, WH; Schotte, A; Van de Weyer, I; Van Gompel, P; Vanhoenacker, P; Wouters, R | 1 |
| Chang, DJ; Eglen, RM; Jasper, JR; Kosaka, A; To, ZP | 1 |
| Boess, FG; Monsma, FJ; Sleight, AJ | 1 |
| Dupre, A; Egan, C; Grinde, E; Hake, M; Herrick-Davis, K; Roth, BL; Teitler, M | 1 |
| Bach, T; Krobert, KA; Kvingedal, AM; Levy, FO; Syversveen, T | 1 |
| Grol, CJ; Schmidt, AW; Sprouse, JS; Vermeulen, ES; Wikström, HV | 1 |
| Bai, F; Johnstone, EM; Little, SP; Nelson, DL; Su, C; Varga, G; Yin, T | 1 |
| Eison, AS; Freeman, R; Wright, RN | 1 |
| Blier, P | 1 |
| Limberger, N; Singer, EA; Starke, K | 1 |
| Anderson, EG; Scroggs, RS | 1 |
| Green, JP; Maayani, S; Shenker, A; Weinstein, H | 1 |
| Galligan, JJ; Pan, H | 1 |
| Baez, M; Cohen, ML; Cushing, DJ; Kursar, JD; Schenck, K | 1 |
| Edvinsson, L; Jansen, I; Olesen, J | 1 |
| Carter, D; Champney, M; Eglen, RM; Hwang, B | 1 |
| Frölich, D; Göthert, M; Likungu, J; Molderings, GJ | 1 |
| Centurión, D; Luján-Estrada, M; Sánchez-López, A; Terrón, JA; Villalón, CM | 1 |
| De Vries, P; Heiligers, JP; Saxena, PR; Villalón, CM | 1 |
| Bragadóttir, R; Jarkman, S; Kato, M | 1 |
| Coupar, IM; Hemedah, M; Mitchelson, FJ | 1 |
| Iwano, H; Kitazawa, T; Taneike, T; Yamada, Y; Yokota, H; Yuasa, A | 1 |
| Bravo, G; Centurión, D; De Vries, P; Ortiz, MI; Saxena, PR; Villalón, CM | 1 |
| Centurión, D; Sánchez-López, A; Saxena, PR; Villalón, CM | 1 |
| Bernhard, M; Bobirnac, I; Dev, KK; Feuerbach, D; Keser, C; Loetscher, E; Mahé, C; Schoeffter, P | 1 |
| Bobirnac, I; Dev, KK; Loetscher, E; Mahé, C; Otten, U; Schoeffter, P | 1 |
| Choo, HY; Kim, HJ; Kim, T; Kostenis, E; Nam, G; Pae, AN; Rhim, H; Roh, EJ; Yun, HM | 1 |
2 review(s) available for 5-carboxamidotryptamine and 5-methoxytryptamine
| Article | Year |
|---|---|
Central serotonin receptors as targets for drug research.
Topics: Animals; Humans; Receptors, Serotonin; Research Design; Serotonin | 1987 |
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7).
Topics: Animals; Humans; Ligands; Receptors, Serotonin; Serotonin Agents; Serotonin Antagonists; Serotonin Receptor Agonists | 2003 |
39 other study(ies) available for 5-carboxamidotryptamine and 5-methoxytryptamine
| Article | Year |
|---|---|
Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.
Topics: Amino Acid Sequence; Animals; Brain; Cattle; Cell Membrane; Cloning, Molecular; DNA Probes; Female; Gene Library; Humans; Kinetics; Molecular Sequence Data; Multigene Family; Placenta; Pregnancy; Receptors, Serotonin; Recombinant Proteins; Sequence Homology, Nucleic Acid | 1992 |
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.
Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; Cyclic AMP; GTP-Binding Proteins; Humans; Molecular Sequence Data; Pertussis Toxin; Receptors, Serotonin; Virulence Factors, Bordetella | 1991 |
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 1993 |
Cloning of a novel human serotonin receptor (5-HT7) positively linked to adenylate cyclase.
Topics: Adenylyl Cyclases; Base Sequence; Cloning, Molecular; DNA Primers; Humans; Molecular Sequence Data; Receptors, Serotonin; Sequence Alignment; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists; Signal Transduction | 1993 |
Cloning of another human serotonin receptor (5-HT1F): a fifth 5-HT1 receptor subtype coupled to the inhibition of adenylate cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain Chemistry; Cloning, Molecular; Colforsin; Dose-Response Relationship, Drug; Gene Library; Guinea Pigs; Humans; Indoles; Lymphocytes; Molecular Sequence Data; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Serotonin; Serotonin Receptor Agonists; Spiperone; Sulfonamides; Sumatriptan; Tissue Distribution | 1993 |
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Cell Line; Cell Membrane; Cloning, Molecular; Cyclic AMP; Gene Expression; Kidney Tubules, Proximal; Lysergic Acid Diethylamide; Molecular Sequence Data; Oligodeoxyribonucleotides; Polymerase Chain Reaction; Radioligand Assay; Rats; Receptors, Serotonin; Recombinant Proteins; Serotonin; Transfection | 1993 |
Molecular cloning of a mammalian serotonin receptor that activates adenylate cyclase.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Base Sequence; Brain; Cloning, Molecular; Cyclic AMP; DNA; Drosophila; Enzyme Activation; Humans; Intestinal Mucosa; Mice; Molecular Sequence Data; Myocardium; Receptors, Serotonin; Sequence Homology, Amino Acid; Serotonin Antagonists; Serotonin Receptor Agonists | 1993 |
Molecular cloning, characterization, and localization of a high-affinity serotonin receptor (5-HT7) activating cAMP formation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; CHO Cells; Cricetinae; Cyclic AMP; DNA; Genomic Library; Kinetics; Lysergic Acid Diethylamide; Mianserin; Molecular Sequence Data; Multigene Family; Oligodeoxyribonucleotides; Organ Specificity; Rats; Receptors, Serotonin; Restriction Mapping; Serotonin; Serotonin Receptor Agonists; Transfection | 1993 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate; Male; Muscle Contraction; Muscle, Smooth; Radioligand Assay; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Temperature | 1993 |
Cloning, characterization, and chromosomal localization of a human 5-HT6 serotonin receptor.
Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Antipsychotic Agents; Base Sequence; Brain Chemistry; Cell Line, Transformed; Chlorocebus aethiops; Chromosome Mapping; Chromosomes, Human, Pair 1; Cloning, Molecular; Clozapine; DNA, Complementary; Genes; Humans; Kinetics; Molecular Sequence Data; Open Reading Frames; Protein Conformation; Rats; Receptors, Serotonin; Recombinant Proteins; Sequence Alignment; Sequence Homology, Nucleic Acid; Serotonin Agents; Signal Transduction; Species Specificity | 1996 |
Binding of arylpiperazines, (aryloxy)propanolamines, and tetrahydropyridylindoles to the 5-HT1A receptor: contribution of the molecular lipophilicity potential to three-dimensional quantitative structure-affinity relationship models.
Topics: Indoles; Ligands; Models, Molecular; Molecular Conformation; Molecular Structure; Piperazines; Propanolamines; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes | 1996 |
Two amino acid differences in the sixth transmembrane domain are partially responsible for the pharmacological differences between the 5-HT1D beta and 5-HT1E 5-hydroxytryptamine receptors.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Binding, Competitive; Chlorocebus aethiops; Cloning, Molecular; COS Cells; DNA Primers; Ergolines; Glutamic Acid; Humans; Isoleucine; Kinetics; Ligands; Lysine; Models, Structural; Molecular Sequence Data; Point Mutation; Polymerase Chain Reaction; Protein Structure, Secondary; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Serotonin; Transfection | 1996 |
Alniditan, a new 5-hydroxytryptamine1D agonist and migraine-abortive agent: ligand-binding properties of human 5-hydroxytryptamine1D alpha, human 5-hydroxytryptamine1D beta, and calf 5-hydroxytryptamine1D receptors investigated with [3H]5-hydroxytryptamin
Topics: Animals; Benzopyrans; Cattle; Cloning, Molecular; Glioma; HeLa Cells; Humans; Mice; Migraine Disorders; Propylamines; Protein Binding; Pyrimidines; Radioligand Assay; Receptors, Serotonin; Serotonin Receptor Agonists; Signal Transduction; Tritium; Tumor Cells, Cultured; Vasoconstrictor Agents | 1996 |
Cloning, expression and pharmacology of a truncated splice variant of the human 5-HT7 receptor (h5-HT7b).
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Cyclic AMP; DNA, Complementary; Humans; Molecular Sequence Data; Placenta; Radioligand Assay; Rats; Receptors, Serotonin; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid | 1997 |
Identification of residues in transmembrane regions III and VI that contribute to the ligand binding site of the serotonin 5-HT6 receptor.
Topics: Adenylyl Cyclases; Amino Acid Substitution; Binding Sites; Binding, Competitive; Cell Line; Cyclic AMP; Humans; Ligands; Lysergic Acid Diethylamide; Mutagenesis, Site-Directed; Mutation; Receptors, Serotonin; Serotonin; Serotonin Receptor Agonists | 1998 |
Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors.
Topics: Animals; Cell Line; Computer Simulation; GTP-Binding Proteins; Inositol Phosphates; Kinetics; Phosphatidylinositols; Radioligand Assay; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Recombinant Proteins; Serotonin Receptor Agonists; Signal Transduction; Transfection; Tritium | 2000 |
The cloned human 5-HT7 receptor splice variants: a comparative characterization of their pharmacology, function and distribution.
Topics: Adenylyl Cyclases; Alternative Splicing; Binding, Competitive; Brain; Cell Line; Cloning, Organism; Genetic Variation; Humans; Radioligand Assay; Receptors, Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tissue Distribution | 2001 |
Characterization of the 5-HT(7) receptor. Determination of the pharmacophore for 5-HT(7) receptor agonism and CoMFA-based modeling of the agonist binding site.
Topics: Binding Sites; Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Receptors, Serotonin; Serotonin Receptor Agonists; Tetrahydronaphthalenes; Tryptamines | 2003 |
Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Brain; Chickens; Cloning, Molecular; Cricetinae; Dose-Response Relationship, Drug; Gerbillinae; Guinea Pigs; Haplorhini; Humans; Molecular Sequence Data; Protein Binding; Rabbits; Receptors, Serotonin; Serotonin Agents; Swine | 2004 |
Peripheral 5-carboxamidotryptamine induces hindlimb scratching by stimulating 5-HT1A receptors in rats.
Topics: 5-Methoxytryptamine; Animals; Behavior, Animal; Hindlimb; Indoles; Male; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Sulfonamides; Sumatriptan; Tryptamines | 1992 |
Terminal serotonin autoreceptor function in the rat hippocampus is not modified by pertussis and cholera toxins.
Topics: 5-Methoxytryptamine; Adenosine Diphosphate Ribose; Animals; Cholera Toxin; Ethylmaleimide; GTP-Binding Proteins; Hippocampus; In Vitro Techniques; Male; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Virulence Factors, Bordetella | 1991 |
Serotonin uptake blockers influence serotonin autoreceptors by increasing the biophase concentration of serotonin and not through a "molecular link".
Topics: 5-Methoxytryptamine; Animals; Brain; Cerebral Cortex; Electric Stimulation; Female; Hypothalamus; In Vitro Techniques; Male; Rabbits; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1990 |
5-HT1 receptor agonists reduce the Ca+ component of sensory neuron action potentials.
Topics: 5-Methoxytryptamine; Action Potentials; Animals; Anura; Calcium; Ganglia, Spinal; In Vitro Techniques; Neurons, Afferent; Receptors, Serotonin; Serotonin; Tetraethylammonium Compounds | 1990 |
Pharmacological characterization of two 5-hydroxytryptamine receptors coupled to adenylate cyclase in guinea pig hippocampal membranes.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adenylyl Cyclases; Animals; Bufotenin; Guinea Pigs; Hippocampus; Kinetics; Male; Mathematics; Membranes; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Tetrahydronaphthalenes; Tryptamines | 1987 |
Effects of 5-HT1A and 5-HT4 receptor agonists on slow synaptic potentials in enteric neurons.
Topics: 5-Methoxytryptamine; Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cisapride; Dose-Response Relationship, Drug; Electrophysiology; Guinea Pigs; Ileum; Indoles; Male; Membrane Potentials; Myenteric Plexus; Neurons; Piperazines; Piperidines; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 1995 |
Serotonin-induced contraction in canine coronary artery and saphenous vein: role of a 5-HT1D-like receptor.
Topics: 5-Methoxytryptamine; Adrenergic alpha-Antagonists; Animals; Base Sequence; Blotting, Southern; Coronary Vessels; Dioxanes; DNA Primers; Dogs; Dose-Response Relationship, Drug; Gene Expression; Idazoxan; Molecular Sequence Data; Muscle Contraction; Muscle, Smooth, Vascular; Piperazines; Polymerase Chain Reaction; Prazosin; Receptors, Serotonin; RNA, Messenger; Saphenous Vein; Serotonin; Serotonin Receptor Agonists; Sumatriptan; Tryptamines | 1994 |
5-Hydroxytryptamine receptor characterization of human cerebral, middle meningeal and temporal arteries: regional differences.
Topics: 5-Methoxytryptamine; Cerebral Arteries; Humans; Indoles; Ketanserin; Meningeal Arteries; Methiothepin; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides; Sumatriptan; Temporal Arteries; Vasoconstriction; Vasoconstrictor Agents | 1993 |
Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cloning, Molecular; Drug Interactions; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; N,N-Dimethyltryptamine; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Substance P; Sumatriptan; Tryptamines | 1995 |
Inhibition of noradrenaline release via presynaptic 5-HT1D alpha receptors in human atrium.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic Uptake Inhibitors; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cisapride; Corticosterone; Desipramine; Heart Atria; Humans; Indoles; Ketanserin; Male; Middle Aged; Norepinephrine; Oxadiazoles; Piperidines; Receptors, Presynaptic; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Tritium; Tryptamines | 1996 |
Mediation of 5-HT-induced external carotid vasodilatation in GR 127935-pretreated vagosympathectomized dogs by the putative 5-HT7 receptor.
Topics: 5-Methoxytryptamine; Acetylcholine; Animals; Carotid Arteries; Dogs; Hemodynamics; Oxadiazoles; Piperazines; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasodilation | 1997 |
Nature of 5-HT1-like receptors mediating depressor responses in vagosympathectomized rats; close resemblance to the cloned 5-ht7 receptor.
Topics: 5-Methoxytryptamine; Adrenergic beta-Agonists; Animals; Blood Pressure; Clozapine; Ergolines; Heart Rate; Isoproterenol; Lisuride; Male; Metergoline; Methiothepin; Oxadiazoles; Piperazines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Sympathectomy | 1997 |
Serotonin elevates the c-wave of the electroretinogram of the rabbit eye by increasing the transepithelial potential.
Topics: 5-Methoxytryptamine; Animals; Dose-Response Relationship, Drug; Electroretinography; Ergolines; Indoles; Membrane Potentials; Pigment Epithelium of Eye; Rabbits; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Tropisetron | 1997 |
[3H]-Mesulergine labels 5-HT7 sites in rat brain and guinea-pig ileum but not rat jejunum.
Topics: 5-Methoxytryptamine; Animals; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship, Drug; Ergolines; Female; Free Radical Scavengers; Guinea Pigs; Ileum; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Ondansetron; Radioligand Assay; Rats; Rats, Wistar; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sulfonamides; Sumatriptan; Tritium | 1999 |
Smooth muscle layer-dependent distribution of 5-hydroxytryptamine(7) receptor in the porcine myometrium.
Topics: 5-Methoxytryptamine; Animals; Cyclic AMP; Female; Muscle Contraction; Muscle, Smooth; Myometrium; Receptors, Serotonin; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Swine | 2000 |
Further pharmacological analysis of the orphan 5-HT receptors mediating feline vasodepressor responses: close resemblance to the 5-HT7, receptor.
Topics: 5-Methoxytryptamine; Acetylcholine; Animals; Blood Pressure; Cats; Drug Interactions; Female; Heart Rate; Male; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Sumatriptan; Sympathectomy; Vagotomy | 2000 |
Unravelling the pharmacological profile of the canine external carotid vasodilator '5-HT1-like' receptors: coexistence of sympatho-inhibitory 5-HT1B and postjunctional 5-HT7 receptors.
Topics: 5-Methoxytryptamine; Acetylcholine; Animals; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Carotid Artery, External; Chromans; Dogs; Dose-Response Relationship, Drug; Female; Heart Rate; Hemodynamics; Male; Neuromuscular Junction; Oxadiazoles; Piperazines; Piperidones; Receptor, Serotonin, 5-HT1B; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Spiro Compounds; Sumatriptan; Sympathetic Nervous System; Vasodilation | 2001 |
Functional expression of the serotonin 5-HT7 receptor in human glioblastoma cell lines.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Blotting, Western; Cell Line, Tumor; CHO Cells; Cricetinae; Cricetulus; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Protein Isoforms; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin | 2004 |
Serotonin 5-HT7 receptors coupled to induction of interleukin-6 in human microglial MC-3 cells.
Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Blotting, Northern; Blotting, Western; Cell Line; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Gene Expression Regulation; Humans; Interleukin-6; Microglia; Phenols; Receptors, Serotonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Serotonin Agents; Serotonin Antagonists; Sulfonamides; Transfection | 2005 |
Functional human 5-HT6 receptor assay for high throughput screening of chemical ligands and binding proteins.
Topics: 5-Methoxytryptamine; Aniline Compounds; Calcium; Calcium Signaling; Cell Line; Clozapine; Drug Evaluation, Preclinical; GTP-Binding Protein alpha Subunits; GTP-Binding Protein alpha Subunits, Gq-G11; Humans; Molecular Structure; Piperazines; Protein Binding; Proto-Oncogene Proteins c-fyn; Receptors, Serotonin; Reproducibility of Results; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Small Molecule Libraries; Sulfonamides; Transfection; Tryptamines; Xanthenes | 2008 |