5-benzylacyclouridine has been researched along with uridine in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (40.00) | 18.7374 |
| 1990's | 8 (53.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (6.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basso, LA; Campos, MM; de Souza, ON; Erig, T; Farias, CB; Machado, P; Renck, D; Roesler, R; Rosado, LA; Santos, DS; Souto, AA; Timmers, LF | 1 |
| Calabresi, P; Darnowski, JW; Goulette, FA; Handschumacher, RE; Wiegand, RA | 1 |
| Calabresi, P; Chu, SH; Darnowski, JW; Falcone, A; St Clair, MH; Wiemann, MC | 1 |
| Brunetti, I; Calabresi, P; Chu, SH; Darnowski, JW; Falcone, A; Ruprecht, RM | 1 |
| Martin, DS; Sawyer, RC; Stolfi, RL | 1 |
| Darnowski, JW; Handschumacher, RE | 2 |
| Lankelma, J; Laurensse, EJ; Leyva, A; Peters, GJ; Pinedo, HM; van Groeningen, CJ | 1 |
| Cha, S; Chu, HS; el Kouni, MH; Lee, KH | 1 |
| Ayers, O; Cysyk, RL; Monks, A | 1 |
| Anderson, DC; Cretton, EM; el Kouni, MH; Kidd, LB; McClure, HM; Sommadossi, JP | 1 |
| Allegra, CJ; Grogan, L; Sotos, GA | 1 |
| el Kouni, MH; Levesque, DL; Naguib, FN; Panzica, RP; Wang, EC | 1 |
| Baccanari, DP; Chandrasurin, P; Davis, ST; Joyner, SS | 1 |
| Cao, D; Handschumacher, RE; Liu, M; Pizzorno, G; Russell, R | 1 |
1 review(s) available for 5-benzylacyclouridine and uridine
| Article | Year |
|---|---|
Preclinical and clinical aspects of biomodulation of 5-fluorouracil.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Aspartic Acid; Cisplatin; Colorectal Neoplasms; DNA, Neoplasm; Fluorouracil; Humans; Idoxuridine; Immunologic Factors; Interferons; Leucovorin; Methotrexate; Mice; Phosphonoacetic Acid; RNA, Neoplasm; Uracil; Uridine; Zidovudine | 1994 |
14 other study(ies) available for 5-benzylacyclouridine and uridine
| Article | Year |
|---|---|
Design of novel potent inhibitors of human uridine phosphorylase-1: synthesis, inhibition studies, thermodynamics, and in vitro influence on 5-fluorouracil cytotoxicity.
Topics: Antineoplastic Agents; Cell Proliferation; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Fluorouracil; HT29 Cells; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Thermodynamics; Uridine Phosphorylase | 2013 |
Tissue-specific expansion of uridine pools in mice. Effects of benzylacyclouridine, dipyridamole and exogenous uridine.
Topics: Administration, Oral; Animals; Dipyridamole; Drug Synergism; Female; Injections, Intravenous; Mice; Mice, Inbred Strains; Time Factors; Tissue Distribution; Uracil; Uridine; Uridine Phosphorylase | 1991 |
Benzylacyclouridine reverses azidothymidine-induced marrow suppression without impairment of anti-human immunodeficiency virus activity.
Topics: Anemia; Animals; Cell Line; Cytopathogenic Effect, Viral; Female; HIV; Leukopenia; Mice; Mice, Inbred BALB C; Uracil; Uridine; Zidovudine | 1990 |
Different effect of benzylacyclouridine on the toxic and therapeutic effects of azidothymidine in mice.
Topics: Acquired Immunodeficiency Syndrome; Anemia; Animals; Dose-Response Relationship, Drug; Female; Kinetics; Leukemia, Experimental; Leukopenia; Mice; Mice, Inbred BALB C; Rauscher Virus; Uracil; Uridine; Zidovudine | 1990 |
Use of oral uridine as a substitute for parenteral uridine rescue of 5-fluorouracil therapy, with and without the uridine phosphorylase inhibitor 5-benzylacyclouridine.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Chromatography, High Pressure Liquid; Disease Models, Animal; Fluorouracil; Mammary Neoplasms, Experimental; Mice; Pentosyltransferases; Uracil; Uridine; Uridine Phosphorylase | 1989 |
Benzylacyclouridine. Pharmacokinetics, metabolism and biochemical effects in mice.
Topics: Administration, Oral; Animals; Chromatography, High Pressure Liquid; Injections, Intravenous; Metabolic Clearance Rate; Mice; Tissue Distribution; Uracil; Uridine; Uridine Phosphorylase | 1988 |
Uridine-induced hypothermia in mice and rats in relation to plasma and tissue levels of uridine and its metabolites.
Topics: Animals; Body Temperature; Brain; Colonic Neoplasms; Cytidine; Cytidine Deaminase; Dose-Response Relationship, Drug; Female; Hypothermia; Liver; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Rats; Rats, Inbred Strains; Tetrahydrouridine; Thymidine; Uracil; Uridine; Uridine Phosphorylase | 1987 |
Tissue-specific enhancement of uridine utilization and 5-fluorouracil therapy in mice by benzylacyclouridine.
Topics: Animals; Colonic Neoplasms; Female; Fluorouracil; Lethal Dose 50; Mice; Mice, Inbred C57BL; Uracil; Uridine | 1985 |
Inhibition of nucleoside transport in murine lymphoma L5178Y cells and human erythrocytes by the uridine phosphorylase inhibitors 5-benzylacyclouridine and 5-benzyloxybenzylacyclouridine.
Topics: Animals; Biological Transport; Carbon Radioisotopes; Erythrocytes; Kinetics; Leukemia L5178; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Nucleosides; Pentosyltransferases; Uracil; Uridine; Uridine Phosphorylase | 1984 |
Effect of 5-benzylacyclouridine, a potent inhibitor of uridine phosphorylase, on the metabolism of circulating uridine by the isolated rat liver.
Topics: Animals; Kinetics; Liver; Pentosyltransferases; Perfusion; Rats; Rats, Inbred Strains; Uracil; Uridine; Uridine Phosphorylase | 1983 |
Effects of 5-benzylacyclouridine, an inhibitor of uridine phosphorylase, on the pharmacokinetics of uridine in rhesus monkeys: implications for chemotherapy.
Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; Macaca mulatta; Uracil; Uridine; Uridine Phosphorylase | 1995 |
5-Benzylbarbituric acid derivatives, potent and specific inhibitors of uridine phosphorylase.
Topics: Animals; Barbiturates; Humans; Liver; Mice; Uracil; Uridine; Uridine Phosphorylase | 1993 |
Species-dependent differences in the biochemical effects and metabolism of 5-benzylacyclouridine.
Topics: Animals; Female; Half-Life; Kinetics; Liver; Macaca fascicularis; Male; Mice; Rats; Species Specificity; Tissue Extracts; Uracil; Uridine; Uridine Phosphorylase | 1993 |
Expression, characterization, and detection of human uridine phosphorylase and identification of variant uridine phosphorolytic activity in selected human tumors.
Topics: Amino Acid Sequence; Animals; Antibody Specificity; Cloning, Molecular; DNA, Complementary; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Kinetics; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Neoplasms; Rabbits; Sequence Homology, Amino Acid; Uracil; Uridine; Uridine Phosphorylase | 1998 |