5-azacytosine has been researched along with cytosine in 37 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (27.03) | 18.7374 |
| 1990's | 4 (10.81) | 18.2507 |
| 2000's | 12 (32.43) | 29.6817 |
| 2010's | 11 (29.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Friedman, S; Huang, YC | 1 |
| Friedman, S; Som, S; Yang, LF | 1 |
| Cihák, A; Cízková, J; Korbová, L; Kucerová, V; Pískala, A | 1 |
| Fujii, N; Oguma, K | 1 |
| Frahm, J; Hoshino, J; Kröger, H | 1 |
| Jones, PA; Michalowsky, LA | 1 |
| Acs, G; Christman, JK; Schneiderman, N | 2 |
| Friedman, S | 1 |
| Jehn, U; Knüppel, W; Wilmanns, W | 1 |
| Kaczmarek, L; Surmacz, E | 1 |
| Faraggi, M; Riesz, P; Rosenthal, I | 1 |
| Friedman, S; Som, S | 1 |
| Bhagwat, AS; Gabbara, S; Sheluho, D | 1 |
| Cheng, YC; Dutschman, GE; Gullen, EA; Lin, TS; Liu, MC; Luo, MZ; Mozdziesz, DE; Sartorelli, AC | 1 |
| Forood, B; Hebert, N; Katritzky, AR; Rogovoy, BV; Vvedensky, VY | 1 |
| Brank, AS; Christman, JK; Eritja, R; Güimil García, R; Marquez, VE | 1 |
| Pakneshan, P; Rabbani, SA; Xing, RH | 1 |
| Cappellacci, L; Montgomery, JA; Secrist, JA; Tiwari, KN | 1 |
| Hoffman, AR; Hu, JF; Li, T; Sun, Z; Ulaner, GA; Vu, TH; Yang, Y; Yao, X | 1 |
| Colleoni, S; Donofrio, G; Duchi, R; Galli, C; Lagutina, I; Lazzari, G | 1 |
| Bailey, KA; Baylin, S; Carraway, H; Fandy, TE; Gore, SD; Herman, JG; Jiemjit, A | 1 |
| Dracínský, M; Holý, A; Krecmerová, M | 1 |
| Andrei, G; De Clercq, E; Holý, A; Krecmerová, M; Naesens, L; Neyts, J; Snoeck, R; Votruba, I | 1 |
| Brank, AS; Christman, JK; Eritja, R; Marquez, VE; van Bemmel, DM | 1 |
| Huang, X; Wang, X; Yin, J; Zhong, J | 1 |
| Harada, Y; Ichimura, T; Kobayashi, T; Kuramochi, H; Suzuki, T | 1 |
| Holý, A; Krecmerová, M; Masojídková, M | 1 |
| Craddock, C | 1 |
| Gutierrez, JA; Hemeon, I; Ho, MC; Schramm, VL | 1 |
| Bhatnagar, D; Ehrlich, KC; Kale, SP; Wilkinson, JR; Yu, J | 1 |
| Krečmerová, M; Otmar, M | 1 |
| Bai, C; Geng, J; Li, B; Li, S; Liu, J; Ma, L; Song, Q; Wang, H; Wang, L | 1 |
| Andrei, G; Coen, N; Duraffour, S; Krecmerová, M; Naesens, L; Snoeck, R; Van den Oord, J | 1 |
| Ali, ST; Geffertová, D; Havlas, Z; Holý, A; Kašička, V; Krečmerová, M; Šolínová, V | 1 |
| Carlos Borin, A; González, L; Mai, S; Marquetand, P | 1 |
| Deng, P; Jiang, JH | 1 |
2 review(s) available for 5-azacytosine and cytosine
| Article | Year |
|---|---|
[Effect of 5-methylcytosine in DNA and 5-azacytosine on the expression of various genes in vertebrates].
Topics: 5-Methylcytosine; Animals; Chickens; Cytosine; Gene Expression Regulation; Genes, Regulator; Humans; In Vitro Techniques; Methylation; Methyltransferases; Mice; Oncogenes | 1985 |
5-azacytosine compounds in medicinal chemistry: current stage and future perspectives.
Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Azacitidine; Cytosine; DNA Methylation; Drug Discovery; HIV; HIV Infections; Humans; Neoplasms | 2012 |
1 trial(s) available for 5-azacytosine and cytosine
| Article | Year |
|---|---|
Intensive maintenance treatment in acute myelogenous leukemia (AML): single institution experience of a multicenter randomized trial.
Topics: Adolescent; Adult; Aged; Amsacrine; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Cytarabine; Cytosine; Daunorubicin; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Leukemia, Myeloid, Acute; Middle Aged; Random Allocation; Vincristine | 1988 |
34 other study(ies) available for 5-azacytosine and cytosine
| Article | Year |
|---|---|
Inhibition of recA-mediated strand exchange by adducts of azacytosine-containing DNA and the EcoRII methylase.
Topics: Cytosine; DNA; DNA-Cytosine Methylases; Guanidine; Guanidines; Kinetics; Rec A Recombinases; Recombination, Genetic | 1991 |
The core element of the EcoRII methylase as defined by protease digestion and deletion analysis.
Topics: Amino Acid Sequence; Base Sequence; Chromosome Deletion; Cytosine; DNA Mutational Analysis; DNA-Cytosine Methylases; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Escherichia coli; Kinetics; Macromolecular Substances; Molecular Sequence Data; Mutation; Protein Conformation; Restriction Mapping; S-Adenosylmethionine | 1991 |
Depression of experimental gastric ulcers and acute pancreatitis in rats treated by 5-azacytosine, 5-azacytidine and their N-methyl derivatives.
Topics: Animals; Azacitidine; Cytosine; Gastric Acid; Gastric Juice; Gastric Mucosa; Male; Pancreatitis; Rats; Rats, Inbred Strains; Stomach Ulcer | 1986 |
Induction of oligo-2',5'-adenylate synthetase in human lymphoid cells treated with 5-azacytosine and 5-iododeoxyuridine.
Topics: 2',5'-Oligoadenylate Synthetase; Azacitidine; B-Lymphocytes; Cell Line; Cell Transformation, Viral; Cytosine; Enzyme Induction; Herpesvirus 4, Human; Humans; Idoxuridine; Interferon Type I | 1986 |
Suppression of nuclear ADP-ribosyltransferase activity in Ehrlich ascites tumor cells by 5-azacytidine and its analogs.
Topics: Animals; Azacitidine; Carcinoma, Ehrlich Tumor; Cell Nucleus; Cytosine; DNA; Female; Hydroxyurea; Methylation; Mice; Mice, Inbred Strains; Poly(ADP-ribose) Polymerase Inhibitors | 1987 |
Differential nuclear protein binding to 5-azacytosine-containing DNA as a potential mechanism for 5-aza-2'-deoxycytidine resistance.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line; Cell Nucleus; Cytarabine; Cytosine; Decitabine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; Drug Resistance; Methylation; Mice | 1987 |
Formation of highly stable complexes between 5-azacytosine-substituted DNA and specific non-histone nuclear proteins. Implications for 5-azacytidine-mediated effects on DNA methylation and gene expression.
Topics: Animals; Chromosomal Proteins, Non-Histone; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Endonucleases; Gene Expression Regulation; Sarcosine; Single-Strand Specific DNA and RNA Endonucleases; Sodium Chloride | 1985 |
The irreversible binding of azacytosine-containing DNA fragments to bacterial DNA(cytosine-5)methyltransferases.
Topics: Cytosine; Deoxyribonuclease HpaII; DNA Restriction Enzymes; DNA-Cytosine Methylases; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli; Methyltransferases; Molecular Weight; Potassium Chloride; Pronase; S-Adenosylmethionine | 1985 |
Interaction of DNA methyltransferase and other non-histone proteins isolated from Friend erythroleukemia cell nuclei with 5-azacytosine residues in DNA.
Topics: Animals; Cell Line; Cell Nucleus; Chromosomal Proteins, Non-Histone; Cytosine; Deoxyribonucleoproteins; DNA (Cytosine-5-)-Methyltransferases; DNA, Neoplasm; Histones; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Molecular Weight; Protein Binding | 1985 |
Pulse radiolysis studies of some aza analogues of nucleic acid components.
Topics: Aza Compounds; Azacitidine; Azauridine; Cytosine; Pulse Radiolysis; Thymine; Uracil | 1983 |
Inhibition of transcription in vitro by binding of DNA (cytosine-5)-methylases to DNA templates containing cytosine analogs.
Topics: Base Sequence; Cytosine; DNA; DNA-Cytosine Methylases; Exodeoxyribonucleases; Flucytosine; Molecular Sequence Data; RNA; Transcription, Genetic | 1994 |
Cytosine methyltransferase from Escherichia coli in which active site cysteine is replaced with serine is partially active.
Topics: Base Sequence; Binding Sites; Catalysis; Cysteine; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA, Recombinant; Escherichia coli; Methylation; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Serine | 1995 |
Synthesis and biological evaluation of L- and D-configuration 1,3-dioxolane 5-azacytosine and 6-azathymine nucleosides.
Topics: Animals; Anti-HIV Agents; Antineoplastic Agents; Antiviral Agents; Cell Division; Cytosine; Dioxolanes; Hepatitis B virus; Herpesvirus 1, Human; Herpesvirus 2, Human; HIV-1; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Nucleosides; Structure-Activity Relationship; Thymine; Tumor Cells, Cultured | 2000 |
Synthesis of substituted 4(6)-amino-1,3,5-triazin-2-ones and -1,3,5-triazin-2-thiones.
Topics: Antineoplastic Agents; Cytosine; Thiones; Triazines | 2001 |
Synthesis of oligonucleotide inhibitors of DNA (Cytosine-C5) methyltransferase containing 5-azacytosine residues at specific sites.
Topics: Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; Indicators and Reagents; Oligodeoxyribonucleotides, Antisense | 2001 |
Methylation status of uPA promoter as a molecular mechanism regulating prostate cancer invasion and growth in vitro and in vivo.
Topics: Animals; Base Sequence; Blotting, Southern; Cell Division; Cytosine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Sequence Data; Neoplasm Invasiveness; Polymerase Chain Reaction; Promoter Regions, Genetic; Prostate; Prostatic Neoplasms; RNA, Messenger; Sequence Analysis, DNA; Sulfites; Tumor Cells, Cultured; Urokinase-Type Plasminogen Activator | 2003 |
Synthesis and anti-cancer activity of some novel 5-azacytosine nucleosides.
Topics: Antineoplastic Agents; Azacitidine; Carbohydrate Conformation; Cell Line, Tumor; Cell Survival; Cytidine; Cytosine; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Pentoses; Pyrimidine Nucleosides; Sulfur Compounds | 2003 |
Epigenetic regulation of the taxol resistance-associated gene TRAG-3 in human tumors.
Topics: Antineoplastic Agents, Phytogenic; Base Sequence; Cell Line, Tumor; Cytosine; DNA Methylation; DNA Primers; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Neoplasm Proteins; Paclitaxel; Promoter Regions, Genetic; RNA, Messenger | 2004 |
Establishment, differentiation, electroporation, viral transduction, and nuclear transfer of bovine and porcine mesenchymal stem cells.
Topics: Animals; Blastocyst; Cattle; Cell Differentiation; Cell Division; Cell Lineage; Cell Nucleus; Cells, Cultured; Cloning, Organism; Cytosine; Electroporation; Mesenchymal Stem Cells; Nuclear Transfer Techniques; Osteogenesis; Swine; Transduction, Genetic | 2005 |
p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.
Topics: Caffeine; Cell Line, Tumor; CpG Islands; Cyclin-Dependent Kinase Inhibitor p21; Cytosine; DNA Damage; DNA Repair; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Humans; Leukemia; Models, Biological; Models, Genetic; Transcriptional Activation | 2008 |
Study of chemical stability of antivirally active 5-azacytosine acyclic nucleoside phosphonates using NMR spectroscopy.
Topics: Antiviral Agents; Cytosine; Drug Stability; Guanidines; Hydrolysis; Magnetic Resonance Spectroscopy; Nucleosides; Organophosphonates | 2008 |
Intracellular metabolism of the new antiviral compound 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine.
Topics: Animals; Antiviral Agents; Cell Line, Tumor; Cidofovir; Cytosine; DNA Replication; DNA Viruses; DNA, Neoplasm; Drug Stability; Female; Herpesvirus 1, Human; Humans; Lung Neoplasms; Lymphoma, Non-Hodgkin; Mice; Mice, Inbred Strains; Organophosphonates | 2008 |
DNA (Cytosine-C5) methyltransferase inhibition by oligodeoxyribonucleotides containing 2-(1H)-pyrimidinone (zebularine aglycon) at the enzymatic target site.
Topics: Binding Sites; Cytidine; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Models, Molecular; Nucleic Acid Conformation; Oligodeoxyribonucleotides; Protein Conformation; Structure-Activity Relationship | 2009 |
DNA methyltransferase inhibitors increase baculovirus-mediated gene expression in mammalian cells when applied before infection.
Topics: Animals; Azacitidine; Baculoviridae; Cell Line; CHO Cells; Cricetinae; Cricetulus; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Enzyme Inhibitors; Gene Expression Regulation; Genetic Vectors; Humans | 2010 |
Intersystem crossing to excited triplet state of aza analogues of nucleic acid bases in acetonitrile.
Topics: Absorption; Acetonitriles; Adenine; Aza Compounds; Azaguanine; Cytosine; Nucleic Acids; Quantum Theory; Singlet Oxygen; Solvents; Spectrum Analysis; Uracil | 2009 |
Acyclic nucleoside phosphonates with 5-azacytosine base moiety substituted in C-6 position.
Topics: Animals; Antiviral Agents; Cell Line; Chlorocebus aethiops; Cytosine; Humans; Nucleosides; Organophosphonates; Vero Cells; Virus Diseases; Viruses | 2010 |
Epigenetic manipulation of the immune response: a novel treatment strategy in hematologic malignancies.
Topics: Antigens, Neoplasm; Chromatin; CpG Islands; Cytosine; DNA Methylation; Epigenesis, Genetic; Hematologic Neoplasms; Histone Deacetylase Inhibitors; Humans; Immunity, Cellular; Leukemia, Myeloid, Acute; Methyltransferases; Myelodysplastic Syndromes; Neoplasm Proteins; Promoter Regions, Genetic | 2011 |
Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay.
Topics: Azacitidine; Bacteria; Cytosine; Deoxyadenosines; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Assays; Humans; Kinetics; Light; Luciferases; S-Adenosylhomocysteine; S-Adenosylmethionine; Thionucleosides | 2011 |
Expression profiling of non-aflatoxigenic Aspergillus parasiticus mutants obtained by 5-azacytosine treatment or serial mycelial transfer.
Topics: Aflatoxins; Aspergillus; Cloning, Molecular; Cytosine; Down-Regulation; Expressed Sequence Tags; Gene Expression Profiling; Gene Expression Regulation, Fungal; Multigene Family; Oligonucleotide Array Sequence Analysis; Phenotype; Transcription, Genetic | 2011 |
Preparation and adsorption performance of 5-azacytosine-functionalized hydrothermal carbon for selective solid-phase extraction of uranium.
Topics: Adsorption; Carbon; Cytosine; Hot Temperature; Microspheres; Molecular Structure; Solid Phase Extraction; Uranium | 2012 |
Evaluation of novel acyclic nucleoside phosphonates against human and animal gammaherpesviruses revealed an altered metabolism of cyclic prodrugs upon Epstein-Barr virus reactivation in P3HR-1 cells.
Topics: Animals; Antiviral Agents; Apoptosis; Blotting, Western; Cells, Cultured; Cidofovir; Cyclic AMP; Cytosine; Gammaherpesvirinae; Herpesviridae Infections; Humans; Kidney; Lymphoma, B-Cell; Mice; Mice, Inbred BALB C; NIH 3T3 Cells; Organophosphonates; Organophosphorus Compounds; Prodrugs; Tumor Virus Infections; Virus Activation; Virus Replication | 2013 |
Investigation of the acid-base and electromigration properties of 5-azacytosine derivatives using capillary electrophoresis and density functional theory calculations.
Topics: Acids; Cytosine; Electrolytes; Electrophoresis, Capillary; Hydrogen-Ion Concentration; Osmolar Concentration; Quantum Theory; Thermodynamics | 2017 |
Ab initio molecular dynamics relaxation and intersystem crossing mechanisms of 5-azacytosine.
Topics: Cytosine; Electronics; Molecular Dynamics Simulation | 2017 |
Discovery of New Inhibitors of Transforming Growth Factor-Beta Type 1 Receptor by Utilizing Docking and Structure-Activity Relationship Analysis.
Topics: Cytosine; Fluorouracil; Humans; Mercaptopurine; Molecular Docking Simulation; Receptor, Transforming Growth Factor-beta Type I; Structure-Activity Relationship | 2019 |