5-aza-2'-deoxycytidine-5'-triphosphate has been researched along with azacitidine in 23 studies
| Studies (5-aza-2'-deoxycytidine-5'-triphosphate) | Trials (5-aza-2'-deoxycytidine-5'-triphosphate) | Recent Studies (post-2010) (5-aza-2'-deoxycytidine-5'-triphosphate) | Studies (azacitidine) | Trials (azacitidine) | Recent Studies (post-2010) (azacitidine) |
|---|---|---|---|---|---|
| 24 | 0 | 12 | 7,474 | 479 | 3,782 |
| Protein | Taxonomy | 5-aza-2'-deoxycytidine-5'-triphosphate (IC50) | azacitidine (IC50) |
|---|---|---|---|
| DNA (cytosine-5)-methyltransferase 1 | Homo sapiens (human) | 0.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (17.39) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 12 (52.17) | 24.3611 |
| 2020's | 1 (4.35) | 2.80 |
| Authors | Studies |
|---|---|
| Bonnac, L; Clouser, CL; Daly, MB; Kim, B; Landman, SR; Mansky, LM; Patterson, SE; Rawson, JM; Reilly, CS; Roth, ME; Xie, J | 1 |
| Drahovsky, D; Jovin, TM; Kalisch, BW; McIntosh, LP; Pfeifer, GP; Sprinzl, M; van de Sande, JH; Zielinski, WS | 1 |
| Bouchard, J; Momparler, RL | 1 |
| Bartolucci, S; Bouchard, J; Momparler, LF; Momparler, RL; Rossi, M; Vaccaro, C | 1 |
| Attadia, V; Cimino, R; Maio, M; Pinto, A; Zappacosta, S | 1 |
| Saitoh, S; Wada, T | 1 |
| Endo, T; Iku, S; Imai, K; Itoh, F; Iwata, N; Kaneto, H; Karino, Y; Kikuchi, T; Ozeki, I; Sasaki, S; Satoh, M; Satoh, T; Suzuki, H; Toyota, J; Yamamoto, H | 1 |
| Chernukhin, I; D'Arcy, V; Delgado, MD; Docquier, F; Klenova, E; León, J; Torrano, V | 1 |
| Derheimer, FA; Dixon, JE; Hanasoge, S; Li, L; Ljungman, M; Paulsen, MT; Starks, AM | 1 |
| Abraham, JM; Agarwal, R; Beer, D; Cheng, Y; David, S; Hamilton, JP; Ito, T; Jin, Z; Kan, T; Meltzer, SJ; Montgomery, E; Mori, Y; Olaru, A; Paun, B; Sato, F; Yang, J | 1 |
| Hiraga, J; Kinoshita, T; Kiyoi, H; Naoe, T; Shimada, K; Sugimoto, T; Tomita, A | 1 |
| Bélanger, AS; Guillemette, C; Harvey, M; Tojcic, J | 1 |
| Bhan, S; Califano, JA; Fakhry, C; Glazer, CA; Ha, PK; Hoque, MO; Moskaluk, CA; Shao, C; Sharma, R; Sidransky, D; Sun, W; Tan, M; Westra, WH; Zhong, X | 1 |
| Hitoshi, S; Hosoya, T; Hotta, Y; Ikenaka, K; Ishino, Y; Jasmine, S; Kato, S; Kondo, T; Kumar, A; Tanaka, KF | 1 |
| Han, L; Hou, H; Li, H; Liu, J; Tong, S; Wang, XQ; Yan, Q; Yang, X | 1 |
| Chen, Y; Leach, R; Wang, K | 1 |
| Hu, J; Jiang, B; Liang, Y; Wang, B; Wang, X; Wang, Z; Xu, B; Zhang, Y; Zhou, J | 1 |
| Alp, E; Gurocak, S; Konac, E; Menevse, S; Onen, IH; Sozen, S; Varol, N; Yilmaz, A | 1 |
| Dong, Z; Guo, W; Guo, X; Guo, Y; Kuang, G; Shen, S; Wang, C | 1 |
| Apa, AG; Arruda, VO; de Rezende, LM; Klumb, CE; Mazzoccoli, L; Reis, FR; Robaina, MC | 1 |
| Bonnac, L; Clouser, CL; Daly, MB; Kim, B; Landman, SR; Mansky, LM; Patterson, SE; Rawson, JM; Reilly, CS; Xie, J | 1 |
| Bisogno, G; Celegato, B; Lanfranchi, G; Martini, P; Millino, C; Pacchioni, B; Poli, E; Romualdi, C; Rosolen, A; Tombolan, L; Zin, A | 1 |
| Daly, MB; Greggs, WM; Kim, B; Mansky, LM; McDaniel, YZ; Patterson, SE; Roth, M; Talledge, N | 1 |
23 other study(ies) available for 5-aza-2'-deoxycytidine-5'-triphosphate and azacitidine
| Article | Year |
|---|---|
Synergistic reduction of HIV-1 infectivity by 5-azacytidine and inhibitors of ribonucleotide reductase.
Topics: Anti-HIV Agents; Azacitidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; HIV Infections; HIV-1; Humans; Microbial Sensitivity Tests; Molecular Structure; Ribonucleotide Reductases; Structure-Activity Relationship | 2016 |
Synthesis and characterization of poly[d(G-z5C)]. B-Z transition and inhibition of DNA methylase.
Topics: Azacitidine; Cytidine Triphosphate; DNA (Cytosine-5-)-Methyltransferases; Female; Humans; Indicators and Reagents; Kinetics; Nucleic Acid Conformation; Placenta; Polydeoxyribonucleotides; Pregnancy; Spectrophotometry, Ultraviolet | 1985 |
Incorporation of 5-Aza-2'-deoxycytidine-5'-triphosphate into DNA. Interactions with mammalian DNA polymerase alpha and DNA methylase.
Topics: Animals; Antineoplastic Agents; Azacitidine; Cattle; Cytidine Triphosphate; Cytosine Nucleotides; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Polymerase II; DNA-Directed DNA Polymerase; Kinetics; Methylation; Methyltransferases; Mice; Templates, Genetic | 1983 |
Kinetic interaction of 5-AZA-2'-deoxycytidine-5'-monophosphate and its 5'-triphosphate with deoxycytidylate deaminase.
Topics: Allosteric Regulation; Animals; Azacitidine; Cytidine Triphosphate; Cytosine Nucleotides; DCMP Deaminase; Deoxycytosine Nucleotides; Kinetics; Nucleotide Deaminases; Perissodactyla; Spleen | 1984 |
Modulation of HLA-DR antigens expression in human myeloid leukaemia cells by cytarabine and 5-aza-2'-deoxycytidine.
Topics: Azacitidine; Cells, Cultured; Cytarabine; Cytidine Triphosphate; Cytosine Nucleotides; Gene Expression Regulation; Histocompatibility Antigens Class II; HLA-DR Antigens; Humans; Leukemia, Myeloid, Acute | 1984 |
Parent-of-origin specific histone acetylation and reactivation of a key imprinted gene locus in Prader-Willi syndrome.
Topics: Acetylation; Alleles; Azacitidine; Chromatin; Chromosomes, Human, Pair 15; CpG Islands; Cytidine Triphosphate; DNA Methylation; DNA Modification Methylases; Female; Gene Expression Regulation; Gene Silencing; Genomic Imprinting; Histones; Humans; Male; Prader-Willi Syndrome; Precipitin Tests | 2000 |
Frequent hypermethylation of CpG islands and loss of expression of the 14-3-3 sigma gene in human hepatocellular carcinoma.
Topics: 14-3-3 Proteins; Azacitidine; Base Sequence; Carcinoma, Hepatocellular; CpG Islands; Cytidine Triphosphate; Cytoplasm; DNA Methylation; DNA Mutational Analysis; Gene Silencing; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Polymorphism, Single-Stranded Conformational; Sulfites; Tyrosine 3-Monooxygenase | 2000 |
CTCF regulates growth and erythroid differentiation of human myeloid leukemia cells.
Topics: Azacitidine; Blotting, Northern; Blotting, Western; CCCTC-Binding Factor; Cell Differentiation; Cell Lineage; Cell Proliferation; Cytidine Triphosphate; DNA-Binding Proteins; Gene Expression Regulation; Hematopoietic Stem Cells; Humans; K562 Cells; Leukemia, Myeloid; Oligonucleotides, Antisense; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Transfection; Zinc Fingers | 2005 |
The p53-targeting human phosphatase hCdc14A interacts with the Cdk1/cyclin B complex and is differentially expressed in human cancers.
Topics: Azacitidine; CDC2 Protein Kinase; Cell Line; Cell Line, Tumor; Cyclin B; Cytidine Triphosphate; Gene Expression Regulation, Neoplastic; Genes, p53; Humans; Mitosis; Models, Biological; Phosphoric Monoester Hydrolases; Phosphorylation; Proteasome Inhibitors; Protein Binding; Protein Tyrosine Phosphatases | 2006 |
Hypermethylation of the nel-like 1 gene is a common and early event and is associated with poor prognosis in early-stage esophageal adenocarcinoma.
Topics: Aged; Azacitidine; Calcium-Binding Proteins; Cell Line, Tumor; Cytidine Triphosphate; DNA Methylation; Esophageal Neoplasms; Humans; Middle Aged; Neoplasm Staging; Nerve Tissue Proteins; Prognosis; Promoter Regions, Genetic; RNA, Messenger; Survival Rate; Time Factors | 2007 |
Escape mechanisms from antibody therapy to lymphoma cells: downregulation of CD20 mRNA by recruitment of the HDAC complex and not by DNA methylation.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antigens, CD20; Azacitidine; Cell Line, Tumor; Cytidine Triphosphate; DNA Methylation; Down-Regulation; Drug Resistance, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Histone Deacetylase 1; Humans; Lymphoma, B-Cell; Promoter Regions, Genetic; Repressor Proteins; Rituximab; Sin3 Histone Deacetylase and Corepressor Complex | 2009 |
Regulation of UGT1A1 and HNF1 transcription factor gene expression by DNA methylation in colon cancer cells.
Topics: Azacitidine; Base Sequence; Colonic Neoplasms; CpG Islands; Cytidine Triphosphate; DNA Methylation; Electrophoretic Mobility Shift Assay; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; HCT116 Cells; Hepatocyte Nuclear Factor 1; HT29 Cells; Humans; Molecular Sequence Data; Promoter Regions, Genetic; Up-Regulation | 2010 |
Integrated, genome-wide screening for hypomethylated oncogenes in salivary gland adenoid cystic carcinoma.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Aquaporin 1; Azacitidine; Carcinoma, Adenoid Cystic; Cell Line; Cell Line, Tumor; Cell Proliferation; Cytidine Triphosphate; DNA Methylation; Epigenomics; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Genetic Testing; Genome-Wide Association Study; Humans; Male; Middle Aged; Oncogenes; Salivary Gland Neoplasms; Up-Regulation | 2011 |
Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells.
Topics: Animals; Azacitidine; Basic Helix-Loop-Helix Transcription Factors; Brain; Bromodeoxyuridine; Chromatin Immunoprecipitation; Cloning, Molecular; Cytidine Triphosphate; DNA Methylation; DNA-Binding Proteins; Electroporation; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation; Green Fluorescent Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neural Stem Cells; Neuropeptides; Nuclear Proteins; Organ Culture Techniques; Receptors, Notch; Repressor Proteins; RNA, Messenger; Signal Transduction; Transcription Factors | 2011 |
Differential fucosyltransferase IV expression in squamous carcinoma cells is regulated by promoter methylation.
Topics: Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; CpG Islands; Cytidine Triphosphate; DNA Methylation; Fucosyltransferases; Gene Expression Regulation, Neoplastic; Humans; Lewis X Antigen; Promoter Regions, Genetic | 2012 |
5-Aza-dC treatment induces mesenchymal-to-epithelial transition in 1st trimester trophoblast cell line HTR8/SVneo.
Topics: Azacitidine; Cadherins; Cell Line; Cytidine Triphosphate; DNA Methylation; DNA-Cytosine Methylases; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation; Humans; Keratin-7; Pregnancy; Pregnancy Trimester, First; Trophoblasts | 2013 |
Epigenetic silencing of miR-126 contributes to tumor invasion and angiogenesis in colorectal cancer.
Topics: 3' Untranslated Regions; Azacitidine; Calcium-Binding Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cytidine Triphosphate; DNA Methylation; EGF Family of Proteins; Endothelial Growth Factors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; MicroRNAs; Neoplasm Invasiveness; Neovascularization, Pathologic; Promoter Regions, Genetic; RNA, Messenger; Vascular Endothelial Growth Factor A | 2013 |
The epigenetically regulated effects of Wnt antagonists on the expression of genes in the apoptosis pathway in human bladder cancer cell line (T24).
Topics: Antineoplastic Agents; Apoptosis; Azacitidine; beta Catenin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cyclin D; Cytidine Triphosphate; Dose-Response Relationship, Drug; Epigenomics; Gene Expression Regulation, Neoplastic; Genes, myc; Humans; Hydroxamic Acids; Urinary Bladder Neoplasms; Wnt Proteins | 2014 |
RASSF5A, a candidate tumor suppressor, is epigenetically inactivated in esophageal squamous cell carcinoma.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Alternative Splicing; Apoptosis; Apoptosis Regulatory Proteins; Azacitidine; Biomarkers, Tumor; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Proliferation; Cytidine Triphosphate; DNA Methylation; Esophageal Neoplasms; Esophagus; Female; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Humans; Hydroxamic Acids; Male; Middle Aged; Monomeric GTP-Binding Proteins; Neoplasm Invasiveness; Prognosis; Promoter Regions, Genetic; Protein Isoforms; Protein Synthesis Inhibitors; RNA, Messenger, Stored | 2015 |
Deregulation of DNMT1, DNMT3B and miR-29s in Burkitt lymphoma suggests novel contribution for disease pathogenesis.
Topics: Adolescent; Azacitidine; Burkitt Lymphoma; Cell Line, Tumor; Child; Child, Preschool; Cyclin-Dependent Kinase Inhibitor p16; Cytidine Triphosphate; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Female; Gene Expression Regulation, Neoplastic; Humans; Male; MicroRNAs; Promoter Regions, Genetic; RNA, Messenger | 2015 |
5-Azacytidine Enhances the Mutagenesis of HIV-1 by Reduction to 5-Aza-2'-Deoxycytidine.
Topics: Anti-HIV Agents; Azacitidine; Chromatography, Liquid; Cytidine Triphosphate; Decitabine; DNA, Viral; HEK293 Cells; HIV Reverse Transcriptase; HIV-1; Humans; Mutagenesis; Oxidation-Reduction; Proviruses; Reverse Transcriptase Inhibitors; Reverse Transcription; Ribonucleotide Reductases; Sequence Analysis, DNA; Tandem Mass Spectrometry | 2016 |
Global DNA methylation profiling uncovers distinct methylation patterns of protocadherin alpha4 in metastatic and non-metastatic rhabdomyosarcoma.
Topics: Azacitidine; Biopsy; Cell Adhesion Molecules, Neuronal; Cell Line, Tumor; Cluster Analysis; Cytidine Triphosphate; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genome-Wide Association Study; Humans; Hydroxamic Acids; Neoplasm Metastasis; Neuropeptides; Promoter Regions, Genetic; Protocadherins; Receptors, Cell Surface; Rhabdomyosarcoma; Transcriptome | 2016 |
Distinct Antiretroviral Mechanisms Elicited by a Viral Mutagen.
Topics: Animals; Antiviral Agents; Azacitidine; Cats; Cytidine Triphosphate; HIV; HIV Infections; Humans; Leukemia Virus, Feline; Leukemia Virus, Murine; Leukemia, Experimental; Mice; Mutagenesis; Mutagens; Mutation; Retroviridae Infections; Tumor Virus Infections; Virus Replication | 2021 |