Compounds > 5-aza-2'-deoxycytidine-5'-monophosphate

Page last updated: 2024-09-03

5-aza-2'-deoxycytidine-5'-monophosphate and azacitidine

5-aza-2'-deoxycytidine-5'-monophosphate has been researched along with azacitidine in 11 studies

Compound Research Comparison

Studies (5-aza-2'-deoxycytidine-5'-monophosphate)	Trials (5-aza-2'-deoxycytidine-5'-monophosphate)	Recent Studies (post-2010) (5-aza-2'-deoxycytidine-5'-monophosphate)	Studies (azacitidine)	Trials (azacitidine)	Recent Studies (post-2010) (azacitidine)
11	0	5	7,474	479	3,782

Protein Interaction Comparison

Protein	Taxonomy	5-aza-2'-deoxycytidine-5'-monophosphate (IC50)	azacitidine (IC50)
DNA (cytosine-5)-methyltransferase 1	Homo sapiens (human)		0.3

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (18.18)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (36.36)	29.6817
2010's	5 (45.45)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bartolucci, S; Bouchard, J; Momparler, LF; Momparler, RL; Nucci, R; Raia, CA; Rossi, M; Sepe, S; Vaccaro, C	1
Bartolucci, S; Bouchard, J; Momparler, LF; Momparler, RL; Rossi, M; Vaccaro, C	1
Magdinier, F; Wolffe, AP	1
Marx, J	1
Brena, RM; Hackanson, B; Morrison, C; Otterson, GA; Plass, C; Tada, Y	1
Hu, XZ; Jiang, H; Lipsky, RH; Marini, AM; Pan, H; Tian, F; Wu, X	1
Chen, H; Li, Q	1
Bernardo, V; da Silva, DC; de Souza, CF; Jasiulionis, MG; Lopes, JD; Mai, S; Monteiro, AC; Silva, AG; Xander, P	1
Bian, EB; Hu, W; Huang, C; Li, J; Liu, LP; Lv, XW; Ma, TT; Shi, KH; Tao, H; Yang, JJ; Zhang, L	1
Fan, D; Nie, Y; Shi, Y; Wu, K; Wu, Q; Xia, L; Yang, Z	1
Huang, YT; Liu, BH; Lu, CC; Wu, TS; Yu, FY	1

Other Studies

11 other study(ies) available for 5-aza-2'-deoxycytidine-5'-monophosphate and azacitidine

Article	Year
5-AZA-2'-deoxycytidine synergistic action with thymidine on leukemic cells and interaction of 5-AZA-dCMP with dCMP deaminase. Advances in experimental medicine and biology, 1986, Volume: 195 Pt B Topics: Animals; Azacitidine; Cell Line; Cell Survival; DCMP Deaminase; Decitabine; Deoxycytosine Nucleotides; DNA, Neoplasm; Drug Synergism; Humans; Methylation; Mice; Nucleotide Deaminases; Thymidine; Thymine Nucleotides	1986
Kinetic interaction of 5-AZA-2'-deoxycytidine-5'-monophosphate and its 5'-triphosphate with deoxycytidylate deaminase. Molecular pharmacology, 1984, Volume: 25, Issue:3 Topics: Allosteric Regulation; Animals; Azacitidine; Cytidine Triphosphate; Cytosine Nucleotides; DCMP Deaminase; Deoxycytosine Nucleotides; Kinetics; Nucleotide Deaminases; Perissodactyla; Spleen	1984
Selective association of the methyl-CpG binding protein MBD2 with the silent p14/p16 locus in human neoplasia. Proceedings of the National Academy of Sciences of the United States of America, 2001, Apr-24, Volume: 98, Issue:9 Topics: Acetylation; Antimetabolites, Antineoplastic; Azacitidine; Chromatin; Colonic Neoplasms; CpG Islands; Cross-Linking Reagents; DNA; DNA Methylation; DNA-Binding Proteins; Formaldehyde; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, p16; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Models, Genetic; Promoter Regions, Genetic; Protein Binding; Proteins; RNA, Messenger; Substrate Specificity; Transcriptional Activation; Tumor Cells, Cultured; Tumor Suppressor Protein p14ARF	2001
Cancer research. Leukemia protein spurs gene silencing. Science (New York, N.Y.), 2002, Feb-08, Volume: 295, Issue:5557 Topics: Azacitidine; Cell Division; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Silencing; Genes, Tumor Suppressor; Humans; Leukemia, Promyelocytic, Acute; Leukocytes; Mutation; Neoplasm Proteins; Oncogene Proteins, Fusion; Promoter Regions, Genetic; Receptors, Retinoic Acid; Tretinoin; Zinc	2002
Epigenetic modulation of tumor suppressor CCAAT/enhancer binding protein alpha activity in lung cancer. Journal of the National Cancer Institute, 2006, Mar-15, Volume: 98, Issue:6 Topics: Acetylation; Azacitidine; Blotting, Northern; Blotting, Southern; Carcinoma, Non-Small-Cell Lung; CCAAT-Enhancer-Binding Protein-alpha; Cell Line, Tumor; Chromatin Immunoprecipitation; CpG Islands; DNA Methylation; DNA-Binding Proteins; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Immunoblotting; Immunohistochemistry; Lung Neoplasms; Methyl-CpG-Binding Protein 2; Mutagenesis; Promoter Regions, Genetic; Sequence Analysis, DNA; Upstream Stimulatory Factors	2006
Dynamic chromatin remodeling events in hippocampal neurons are associated with NMDA receptor-mediated activation of Bdnf gene promoter 1. Journal of neurochemistry, 2009, Volume: 109, Issue:5 Topics: Acetylation; Analysis of Variance; Animals; Azacitidine; Brain-Derived Neurotrophic Factor; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; DNA-Binding Proteins; Embryo, Mammalian; Enzyme Inhibitors; Exons; Hippocampus; Histone Deacetylase 1; Histone Deacetylases; Histones; Hydroxamic Acids; In Vitro Techniques; Lysine; Methyl-CpG-Binding Protein 2; Methylation; N-Methylaspartate; Neurons; Promoter Regions, Genetic; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Repressor Proteins; RNA, Messenger; Time Factors; Transcription Factors	2009
Silencing of Wnt5a during colon cancer metastasis involves histone modifications. Epigenetics, 2012, Jun-01, Volume: 7, Issue:6 Topics: Azacitidine; Cell Line, Tumor; Colonic Neoplasms; DNA Modification Methylases; Gene Expression Regulation, Neoplastic; Gene Silencing; Histone Deacetylases; Histones; Humans; Hydroxamic Acids; Neoplasm Metastasis; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Wnt Proteins; Wnt-5a Protein	2012
Mining gene expression signature for the detection of pre-malignant melanocytes and early melanomas with risk for metastasis. PloS one, 2012, Volume: 7, Issue:9 Topics: Animals; Azacitidine; Cell Line, Tumor; Disease Progression; Epigenesis, Genetic; Female; Gene Expression Profiling; Humans; Hydroxamic Acids; Karyotyping; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Oligonucleotide Array Sequence Analysis; Phenotype; Risk; Skin Neoplasms	2012
DNA methylation and MeCP2 regulation of PTCH1 expression during rats hepatic fibrosis. Cellular signalling, 2013, Volume: 25, Issue:5 Topics: Animals; Azacitidine; Carbon Tetrachloride; Cell Line; Cell Transdifferentiation; DNA Methylation; Gene Expression; Hepatic Stellate Cells; Immunohistochemistry; Kruppel-Like Transcription Factors; Liver Cirrhosis; Male; Methyl-CpG-Binding Protein 2; Myofibroblasts; Patched Receptors; Patched-1 Receptor; Promoter Regions, Genetic; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; RNA Interference; RNA, Messenger; RNA, Small Interfering; Zinc Finger Protein GLI1	2013
Methylation of miR-129-5p CpG island modulates multi-drug resistance in gastric cancer by targeting ABC transporters. Oncotarget, 2014, Nov-30, Volume: 5, Issue:22 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 1; ATP-Binding Cassette Transporters; Azacitidine; Base Sequence; Cell Line, Tumor; CpG Islands; DNA Methylation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Silencing; Genes, Reporter; Humans; Mice; Mice, Inbred BALB C; MicroRNAs; Molecular Sequence Data; Multidrug Resistance-Associated Proteins; Oligonucleotide Array Sequence Analysis; Stomach Neoplasms; Transfection	2014
Aristolochic acid I interferes with the expression of BLCAP tumor suppressor gene in human cells. Toxicology letters, 2018, Volume: 291 Topics: Aristolochic Acids; Azacitidine; Binding Sites; Cell Movement; Cell Survival; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; HEK293 Cells; Humans; Neoplasm Proteins; NF-kappa B; Point Mutation; Promoter Regions, Genetic; RNA, Messenger; Transcription Factor AP-1	2018