5-androstene-3,17-dione has been researched along with androstenedione in 13 studies
| Studies (5-androstene-3,17-dione) | Trials (5-androstene-3,17-dione) | Recent Studies (post-2010) (5-androstene-3,17-dione) | Studies (androstenedione) | Trials (androstenedione) | Recent Studies (post-2010) (androstenedione) |
|---|---|---|---|---|---|
| 15 | 0 | 1 | 7,175 | 377 | 960 |
| Protein | Taxonomy | 5-androstene-3,17-dione (IC50) | androstenedione (IC50) |
|---|---|---|---|
| Cholinesterase | Homo sapiens (human) | 1.55 | |
| Aromatase | Homo sapiens (human) | 0.3 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.6761 | |
| Testosterone 17-beta-dehydrogenase 3 | Homo sapiens (human) | 0.6826 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Labrie, F; Luu-The, V; Takahashi, M | 1 |
| Schoenmakers, HJ; Voogt, PA | 1 |
| Benisek, WF; Holman, CM | 1 |
| Choi, KY; Kim, SW | 1 |
| Blotny, G; Hawkinson, DC; Pollack, RM; Zawrotny, ME | 1 |
| Brothers, P; Ebrahimian, S; Perez-Alvarado, GC; Pollack, RM; Summers, MF; Thornburg, LD; Wu, ZR; Zawrotny, ME | 1 |
| Gillette, PA; Uralets, VP | 1 |
| Choi, G; Choi, KY; Ha, NC; Hong, BH; Kim, MS; Oh, BH | 1 |
| Cha, SS; Choi, KY; Hong, BH; Lee, HS; Nam, GH; Oh, YH; Yun, YS | 1 |
| Houck, WJ; Pollack, RM | 1 |
| Kubli-Garfias, C; Sharma, K; Vázquez-Ramírez, R | 1 |
| Qiu, Z; Zhang, H | 1 |
| Hanna, DM; Khalifa, AE; Tadros, MG | 1 |
13 other study(ies) available for 5-androstene-3,17-dione and androstenedione
| Article | Year |
|---|---|
Differential inhibition of dehydrogenase and 5-ene----4-ene isomerase activities of purified 3 beta-hydroxysteroid dehydrogenase. Evidence for two distinct sites.
Topics: 3-Hydroxysteroid Dehydrogenases; Androstenedione; Azasteroids; Binding Sites; Dehydroepiandrosterone; Dihydrotestosterone; Humans; In Vitro Techniques; Kinetics | 1991 |
In vitro biosynthesis of steroids from androstenedione by the ovaries and pyloric caeca of the starfish Asterias rubens.
Topics: 17-Hydroxysteroid Dehydrogenases; 3-Oxo-5-alpha-Steroid 4-Dehydrogenase; Androstenedione; Animals; Estradiol; Estrone; Female; Gonadal Steroid Hormones; In Vitro Techniques; Ovary; Pylorus; Starfish; Testosterone | 1981 |
Insights into the catalytic mechanism and active-site environment of Comamonas testosteroni delta 5-3-ketosteroid isomerase as revealed by site-directed mutagenesis of the catalytic base aspartate-38.
Topics: Androstenedione; Aspartic Acid; Binding Sites; Catalysis; Cloning, Molecular; Escherichia coli; Gram-Negative Aerobic Bacteria; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Spectrophotometry, Ultraviolet; Steroid Isomerases; Substrate Specificity | 1995 |
Identification of active site residues by site-directed mutagenesis of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Amino Acid Sequence; Androstenedione; Base Sequence; Binding Sites; Molecular Sequence Data; Mutagenesis, Site-Directed; Pseudomonas putida; Recombinant Proteins; Sequence Homology, Amino Acid; Species Specificity; Steroid Isomerases; Structure-Activity Relationship | 1995 |
Mechanism of proton transfer in the isomerization of 5-androstene-3, 17-dione by 3-oxo-delta 5-steroid isomerase and its D38E mutant.
Topics: Androstenedione; Deuterium; Magnetic Resonance Spectroscopy; Mass Spectrometry; Point Mutation; Protons; Stereoisomerism; Steroid Isomerases | 1996 |
Solution structure of 3-oxo-delta5-steroid isomerase.
Topics: Amino Acid Sequence; Androstenedione; Binding Sites; Dimerization; Estradiol; Hydrogen Bonding; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Protein Structure, Secondary; Solutions; Steroid Isomerases | 1997 |
Over-the-counter delta5 anabolic steroids 5-androsen-3,17-dione; 5-androsten-3beta, 17beta-diol; dehydroepiandrosterone; and 19-nor-5-androsten-3,17-dione: excretion studies in men.
Topics: Adult; Anabolic Agents; Androstenediol; Androstenedione; Dehydroepiandrosterone; Gas Chromatography-Mass Spectrometry; Humans; Male; Middle Aged; Nonprescription Drugs; Urinalysis | 2000 |
Pseudoreversion of the catalytic activity of Y14F by the additional substitution(s) of tyrosine with phenylalanine in the hydrogen bond network of delta 5-3-ketosteroid isomerase from Pseudomonas putida biotype B.
Topics: Acrylamide; Amino Acid Substitution; Androstenedione; Catalysis; Crystallography, X-Ray; Deuterium Oxide; Enzyme Activation; Hydrogen Bonding; Kinetics; Mutagenesis, Site-Directed; Phenylalanine; Pseudomonas putida; Spectrometry, Fluorescence; Steroid Isomerases; Structure-Activity Relationship; Substrate Specificity; Tryptophan; Tyrosine | 2001 |
The conserved cis-Pro39 residue plays a crucial role in the proper positioning of the catalytic base Asp38 in ketosteroid isomerase from Comamonas testosteroni.
Topics: Androstenedione; Aspartic Acid; Binding Sites; Catalysis; Catalytic Domain; Comamonas testosteroni; Conserved Sequence; Crystallography, X-Ray; Enzyme Stability; Equilenin; Hydrogen-Ion Concentration; Kinetics; Models, Molecular; Mutation; Proline; Protein Binding; Protein Folding; Protein Structure, Tertiary; Steroid Isomerases; Structure-Activity Relationship; Substrate Specificity; Thermodynamics | 2003 |
Activation enthalpies and entropies for the microscopic rate constants of acetate-catalyzed isomerization of 5-androstene-3,17-dione.
Topics: Acetates; Androstenedione; Hydroxides; Isomerism; Kinetics; Temperature; Thermodynamics | 2003 |
A theoretical model of the catalytic mechanism of the Delta5-3-ketosteroid isomerase reaction.
Topics: Androstenedione; Aspartic Acid; Catalysis; Models, Chemical; Models, Molecular; Stereoisomerism; Steroid Isomerases; Tyrosine | 2006 |
An efficient synthesis of 5alpha-androst-1-ene-3,17-dione.
Topics: Androstenedione; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Spectrophotometry, Ultraviolet | 2006 |
ADIOL protects against 3-NP-induced neurotoxicity in rats: Possible impact of its anti-oxidant, anti-inflammatory and anti-apoptotic actions.
Topics: Analysis of Variance; Androstenedione; Animals; Antioxidants; Apoptosis; Body Weight; Caspase 3; Catalase; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Glutathione; Male; Malondialdehyde; Motor Activity; Neurotoxicity Syndromes; Neurotoxins; Nitric Oxide Synthase Type II; Nitro Compounds; Propionates; Rats; Reflex, Startle | 2015 |