Compounds > 5-aminoorotic acid
Page last updated: 2024-08-25

5-aminoorotic acid and orotic acid

5-aminoorotic acid has been researched along with orotic acid in 6 studies

*Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE. [MeSH]

*Orotic Acid: An intermediate product in PYRIMIDINE synthesis which plays a role in chemical conversions between DIHYDROFOLATE and TETRAHYDROFOLATE. [MeSH]

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's3 (50.00)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Cheleski, J; da Silva, AB; Montanari, CA; Nonato, MC; Pinheiro, MP; Rocha, JR; Wiggers, HJ1
Hasinoff, BB; Patel, D; Schroeder, PE1
Alcolea Palafox, M; Ortiz, S; Rastogi, VK; Tomer, R1
Kostova, I; Martin, J; Mladěnka, P; Saso, L1
Kostova, I; Saso, L; Todorov, L; Traykova, M1
Benarous, K; Kostova, I; Linani, A; Saso, L; Todorov, L; Traykova, M1

Other Studies

6 other study(ies) available for 5-aminoorotic acid and orotic acid

ArticleYear
Novel insights for dihydroorotate dehydrogenase class 1A inhibitors discovery.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:12

    Topics: Amino Acid Sequence; Biocatalysis; Computational Biology; Crystallography, X-Ray; Dihydroorotate Dehydrogenase; Dose-Response Relationship, Drug; Drug Discovery; Enzyme Inhibitors; Humans; Leishmania major; Ligands; Models, Molecular; Molecular Sequence Data; Molecular Structure; Oxidoreductases Acting on CH-CH Group Donors; Protein Structure, Tertiary; Sequence Alignment; Stereoisomerism; Structure-Activity Relationship; Trypanosoma cruzi

2010
The dihydroorotase inhibitor 5-aminoorotic acid inhibits the metabolism in the rat of the cardioprotective drug dexrazoxane and its one-ring open metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:9

    Topics: Animals; Cardiotonic Agents; Dihydroorotase; Doxorubicin; Drug Interactions; Enzyme Inhibitors; Heart; Hydrolysis; Male; Myocardium; Orotic Acid; Rats; Rats, Sprague-Dawley; Razoxane

2008
Solid state simulation of tetramer form of 5-aminoorotic acid: the vibrational spectra and molecular structure study by using MP2 and DFT calculations.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2012, Volume: 97

    Topics: Computer Simulation; Crystallography, X-Ray; Dimerization; Models, Molecular; Molecular Conformation; Orotic Acid; Quantum Theory; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Vibration

2012
Lanthanide(III) complexes are more active inhibitors of the Fenton reaction than pure ligands.
    Redox report : communications in free radical research, 2016, Volume: 21, Issue:2

    Topics: Antioxidants; Coumarins; Hydrogen Peroxide; Iron; Lanthanoid Series Elements; Ligands; Orotic Acid

2016
In Vitro Interaction of 5-Aminoorotic Acid and Its Gallium(III) Complex with Superoxide Radical, Generated by Two Model Systems.
    International journal of molecular sciences, 2020, Nov-23, Volume: 21, Issue:22

    Topics: Animals; Antioxidants; Coordination Complexes; Free Radical Scavengers; Free Radicals; Gallium; Humans; Orotic Acid; Rats; Superoxides; Xanthine Oxidase

2020
Synthesis, Structure and Impact of 5-Aminoorotic Acid and Its Complexes with Lanthanum(III) and Gallium(III) on the Activity of Xanthine Oxidase.
    Molecules (Basel, Switzerland), 2021, Jul-26, Volume: 26, Issue:15

    Topics: Enzyme Inhibitors; Gallium; Lanthanum; Orotic Acid; Superoxides; Xanthine Oxidase

2021