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5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine and n-methylaspartate

5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine has been researched along with n-methylaspartate in 2 studies

Compound Research Comparison

Studies
(5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine)
Trials
(5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine)
Recent Studies (post-2010)
(5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine)
Studies
(n-methylaspartate)
Trials
(n-methylaspartate)
Recent Studies (post-2010) (n-methylaspartate)
100110,408591,902

Protein Interaction Comparison

ProteinTaxonomy5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine (IC50)n-methylaspartate (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)5.175
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)5.175

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grant, KA; Rogawski, MA; Snell, LD; Tabakoff, B; Thurkauf, A1
Jones, SM; Monn, JA; Rice, KC; Rogawski, MA; Thurkauf, A; Yamaguchi, S1

Other Studies

2 other study(ies) available for 5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine and n-methylaspartate

ArticleYear
Comparison of the effects of the uncompetitive N-methyl-D-aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine (ADCI) with its structural analogs dizocilpine (MK-801) and carbamazepine on ethanol withdrawal seizur
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Ethanol; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Seizures; Substance Withdrawal Syndrome; Tremor

1992
Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Administration, Oral; Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Kindling, Neurologic; Male; Mice; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship

1991