5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine has been researched along with dizocilpine in 1 studies
| Studies (5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine) | Trials (5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine) | Recent Studies (post-2010) (5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine) | Studies (dizocilpine) | Trials (dizocilpine) | Recent Studies (post-2010) (dizocilpine) |
|---|---|---|---|---|---|
| 10 | 0 | 1 | 77 | 0 | 30 |
| Protein | Taxonomy | 5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine (IC50) | dizocilpine (IC50) |
|---|---|---|---|
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.002 | |
| Glutamate receptor ionotropic, NMDA 1 | Rattus norvegicus (Norway rat) | 0.0149 | |
| Lysosomal Pro-X carboxypeptidase | Homo sapiens (human) | 0.0053 | |
| Glutamate receptor ionotropic, NMDA 2A | Rattus norvegicus (Norway rat) | 0.0149 | |
| Glutamate receptor ionotropic, NMDA 2B | Rattus norvegicus (Norway rat) | 0.0149 | |
| Glutamate receptor ionotropic, NMDA 2C | Rattus norvegicus (Norway rat) | 0.0149 | |
| Glutamate receptor ionotropic, NMDA 1 | Homo sapiens (human) | 0.009 | |
| Glutamate receptor ionotropic, NMDA 2A | Homo sapiens (human) | 0.029 | |
| Glutamate receptor ionotropic, NMDA 2B | Homo sapiens (human) | 0.009 | |
| Glutamate receptor ionotropic, NMDA 2D | Rattus norvegicus (Norway rat) | 0.0149 | |
| Glutamate receptor ionotropic, NMDA 3B | Rattus norvegicus (Norway rat) | 0.0149 | |
| Sigma non-opioid intracellular receptor 1 | Rattus norvegicus (Norway rat) | 1.7 | |
| Glutamate receptor ionotropic, NMDA 3A | Rattus norvegicus (Norway rat) | 0.0149 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacobson, AE; Mattson, MV; Monn, JA; Rice, KC; Thurkauf, A | 1 |
1 other study(ies) available for 5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine and dizocilpine
| Article | Year |
|---|---|
Synthesis and structure-activity relationship of C5-substituted analogues of (+-)-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine [(+-)-desmethyl-MK801]: ligands for the NMDA receptor-coupled phencyclidine binding site.
Topics: Animals; Binding Sites; Dibenzocycloheptenes; Dizocilpine Maleate; In Vitro Techniques; Ligands; Phencyclidine; Rats; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Receptors, Phencyclidine; Regression Analysis; Structure-Activity Relationship | 1990 |