Compounds > 5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine
Page last updated: 2024-09-03

5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine and dizocilpine maleate

5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine has been researched along with dizocilpine maleate in 7 studies

Compound Research Comparison

Studies
(5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine)		Trials
(5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine)		Recent Studies (post-2010)
(5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine)		Studies
(dizocilpine maleate)		Trials
(dizocilpine maleate)		Recent Studies (post-2010) (dizocilpine maleate)
10017,74191,449

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (85.71)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Grant, KA; Rogawski, MA; Snell, LD; Tabakoff, B; Thurkauf, A1
Jones, SM; Monn, JA; Rice, KC; Rogawski, MA; Thurkauf, A; Yamaguchi, S1
Kokate, TG; Le, DQ; Pannell, LK; Rogawski, MA; Subramaniam, S; Uyakul, D; Yamaguchi, S1
Seidleck, BK; Thurkauf, A; Witkin, JM1
Bubser, M; Felsheim, U; Kronthaler, UO; Rückert, NG; Schmidt, WJ; Zadow, B1
Geter-Douglass, B; Witkin, JM1
Lin, SS; Sun, L1

Other Studies

7 other study(ies) available for 5-aminocarbonyl-10,11-dihydro-5h-dibenzo(a,d)cyclohepten-5,10-imine and dizocilpine maleate

ArticleYear
Comparison of the effects of the uncompetitive N-methyl-D-aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d] cyclohepten-5,10-imine (ADCI) with its structural analogs dizocilpine (MK-801) and carbamazepine on ethanol withdrawal seizur
    The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Ethanol; Male; Mice; Mice, Inbred C57BL; Motor Activity; N-Methylaspartate; Seizures; Substance Withdrawal Syndrome; Tremor

1992
Anticonvulsant activity of the low-affinity uncompetitive N-methyl-D- aspartate antagonist (+-)-5-aminocarbonyl-10,11-dihydro-5H- dibenzo[a,d]cyclohepten-5,10-imine (ADCI): comparison with the structural analogs dizocilpine (MK-801) and carbamazepine.
    The Journal of pharmacology and experimental therapeutics, 1991, Volume: 259, Issue:1

    Topics: Administration, Oral; Animals; Anticonvulsants; Carbamazepine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Kindling, Neurologic; Male; Mice; Motor Activity; N-Methylaspartate; Rats; Rats, Inbred Strains; Seizures; Structure-Activity Relationship

1991
Anticonvulsant efficacy of ADCI (5-aminocarbonyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine) after acute and chronic dosing in mice.
    Epilepsia, 1995, Volume: 36, Issue:6

    Topics: Animals; Anticonvulsants; Brain; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Tolerance; Electroshock; Male; Mice; Receptors, N-Methyl-D-Aspartate; Seizures

1995
Evaluation of ADCI against convulsant and locomotor stimulant effects of cocaine: comparison with the structural analogs dizocilpine and carbamazepine.
    Pharmacology, biochemistry, and behavior, 1994, Volume: 47, Issue:4

    Topics: Animals; Anticonvulsants; Carbamazepine; Cocaine; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Male; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate; Seizures; Substance-Related Disorders

1994
Behavioural pharmacology of the non-competitive NMDA antagonists dextrorphan and ADCI: relations between locomotor stimulation, anticataleptic potential and forebrain dopamine metabolism.
    Naunyn-Schmiedeberg's archives of pharmacology, 1997, Volume: 355, Issue:6

    Topics: Animals; Behavior, Animal; Benzazepines; Dextrorphan; Dizocilpine Maleate; Dopamine; Male; Motor Activity; Prosencephalon; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1997
Behavioral effects and anticonvulsant efficacies of low-affinity, uncompetitive NMDA antagonists in mice.
    Psychopharmacology, 1999, Volume: 146, Issue:3

    Topics: Animals; Anticonvulsants; Discrimination Learning; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Ibogaine; Male; Memantine; Mice; Motor Activity; Receptors, N-Methyl-D-Aspartate

1999
The anticonvulsant SGB-017 (ADCI) blocks voltage-gated sodium channels in rat and human neurons: comparison with carbamazepine.
    Epilepsia, 2000, Volume: 41, Issue:3

    Topics: Animals; Anticonvulsants; Carbamazepine; Cells, Cultured; Disease Models, Animal; Dizocilpine Maleate; Epilepsy; Hippocampus; Humans; Neurons; Patch-Clamp Techniques; Rats; Rats, Long-Evans; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Sodium Channels; Superior Cervical Ganglion

2000