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5-alpha-dihydroprogesterone and pregnenolone

5-alpha-dihydroprogesterone has been researched along with pregnenolone in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19902 (9.09)18.7374
1990's7 (31.82)18.2507
2000's9 (40.91)29.6817
2010's2 (9.09)24.3611
2020's2 (9.09)2.80

Authors

AuthorsStudies
Kollman, PA; Lee, DL; Marsh, FJ; Wolff, ME1
Gynther, J; Honkakoski, P; Jyrkkärinne, J; Mäkinen, J; Poso, A; Savolainen, H1
Clarke, SW; Fowden, AL; Hamon, M; Heap, RB; Houghton, E; Ousey, JC; Rossdale, PD; Silver, M1
Liu, ZH; Wu, JT1
Kohara, H; Shimizu, K; Yamaga, N1
Holtan, DW; Schutzer, WE1
Bãckström, T; Purdy, RH; Seippel, L; Wang, M1
Holtan, DW; Kerby, JL; Schutzer, WE1
Gower, DB; Kraevskaya, MA; Kwan, TK; Makin, HL; Trafford, DJ1
Canosa, LF; Ceballos, NR; Pozzi, AG1
Baumann, N; Eychenne, B; Lachapelle, F; Le Goascogne, C; Robel, P; Tonon, MC1
Baulieu, E; Blair-West, J; Denton, D; Eychenne, B; Ladurelle, N; Robel, P; Schumacher, M1
Kirkman, S; Potgieter, HC; van Aarde, RJ; Wallace, ED1
Allison, CM; Hu, FY; Pearson Murphy, BE; Steinberg, SI1
Debonnel, G; Robichaud, M1
Gilbert Evans, SE; Purdy, RH; Romach, MK; Ross, LE; Sellers, EM1
Cambourg, A; De Nicola, AF; Eychenne, B; Gonzalez, S; Guennoun, R; Labombarda, F; Liere, P; Pianos, A; Schumacher, M1
Beaudry, F; Girard, D; Goff, AK; Jamshidi, AA1
Bedin, R; Biagini, G; Giovannini, G; Lucchi, C; Meletti, S; Monti, G; Rustichelli, C; Trenti, T1
Balthazart, J; Cornil, CA; de Bournonville, MP; Keller, M; Liere, P; Pianos, A; Schumacher, M1
Biagini, G; Costa, AM; Lucchi, C; Messina, S; Rustichelli, C; Senn, L1
Avallone, R; Biagini, G; Codeluppi, A; Filaferro, M; Lucchi, C; Puja, G; Rustichelli, C; Vitale, G1

Other Studies

22 other study(ies) available for 5-alpha-dihydroprogesterone and pregnenolone

ArticleYear
Quantitative relationships between steroid structure and binding to putative progesterone receptors.
    Journal of medicinal chemistry, 1977, Volume: 20, Issue:9

    Topics: Androstenes; Animals; Guinea Pigs; Humans; Hydroxyprogesterones; Protein Binding; Rabbits; Receptors, Progesterone; Sheep; Steroids; Structure-Activity Relationship

1977
Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor.
    Journal of medicinal chemistry, 2003, Oct-23, Volume: 46, Issue:22

    Topics: Animals; Cell Line; Constitutive Androstane Receptor; Histone Acetyltransferases; Humans; Mice; Models, Molecular; Mutation; Nuclear Proteins; Nuclear Receptor Co-Repressor 1; Nuclear Receptor Coactivator 1; Protein Structure, Secondary; Quantitative Structure-Activity Relationship; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Repressor Proteins; Steroids; Transcription Factors; Two-Hybrid System Techniques; Yeasts

2003
Production of 5 alpha-dihydroprogesterone during late pregnancy in the mare.
    Journal of reproduction and fertility. Supplement, 1991, Volume: 44

    Topics: 5-alpha-Dihydroprogesterone; Animals; Female; Fetal Blood; Gestational Age; Horses; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnenolone; Progesterone; Uterus

1991
Conversion of pregnenolone to progesterone by mouse morulae and blastocysts.
    Journal of reproduction and fertility, 1990, Volume: 88, Issue:1

    Topics: 5-alpha-Dihydroprogesterone; Animals; Blastocyst; Cleavage Stage, Ovum; Female; Mice; Mice, Inbred Strains; Morula; Pregnancy; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone

1990
Conversion of 5 alpha-pregnane-3,20-dione, 3 alpha-hydroxy-5 alpha-pregnan-20-one and 3 beta-hydroxy-5 alpha-pregnan-20-one to delta 16-C19 steroids by the reconstituted delta 16-C19-steroid synthetase system.
    Biochimica et biophysica acta, 1989, Apr-25, Volume: 991, Issue:1

    Topics: 5-alpha-Dihydroprogesterone; Androstadienes; Animals; Male; Microsomes; Oxidoreductases; Pregnanediones; Pregnanes; Pregnanolone; Pregnenolone; Progesterone; Steroid 17-alpha-Hydroxylase; Steroids; Substrate Specificity; Swine; Testis

1989
Steroid transformations in pregnant mares: metabolism of exogenous progestins and unusual metabolic activity in vivo and in vitro.
    Steroids, 1996, Volume: 61, Issue:2

    Topics: 5-alpha-Dihydroprogesterone; Animals; Biotransformation; Deuterium; Endometrium; Female; Horses; In Vitro Techniques; Infusions, Intravenous; Liver; Organ Specificity; Pharmaceutical Vehicles; Placenta; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Pregnenolone; Progestins

1996
Relationship between symptom severity and steroid variation in women with premenstrual syndrome: study on serum pregnenolone, pregnenolone sulfate, 5 alpha-pregnane-3,20-dione and 3 alpha-hydroxy-5 alpha-pregnan-20-one.
    The Journal of clinical endocrinology and metabolism, 1996, Volume: 81, Issue:3

    Topics: 5-alpha-Dihydroprogesterone; Adult; Female; Hormones; Humans; Luteal Phase; Menstrual Cycle; Osmolar Concentration; Pregnanediones; Pregnanolone; Pregnenolone; Premenstrual Syndrome

1996
Differential effect of trilostane on the progestin milieu in the pregnant mare.
    Journal of reproduction and fertility, 1996, Volume: 107, Issue:2

    Topics: 3-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Animals; Dihydrotestosterone; Female; Horses; Male; Placenta; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Progestins

1996
Use of gas chromatographic-mass spectrometric techniques in studies of androst-16-ene and androgen biosynthesis in human testis; cytosolic specific binding of 5alpha-androst-16-en-3-one.
    The Journal of steroid biochemistry and molecular biology, 1997, Volume: 60, Issue:1-2

    Topics: 5-alpha-Dihydroprogesterone; Adult; Aged; Androgens; Androstenes; Androstenols; Chromatography, Gas; Cytosol; Humans; Male; Mass Spectrometry; Middle Aged; Pregnanediones; Pregnanolone; Pregnenolone; Testis; Testosterone

1997
Pregnenolone and progesterone metabolism by the testes of Bufo arenarum.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 1998, Volume: 168, Issue:7

    Topics: 5-alpha-Dihydroprogesterone; Androgens; Androstenediol; Androstenedione; Animals; Bufo arenarum; Carbon Radioisotopes; Dehydroepiandrosterone; In Vitro Techniques; Male; Pregnanediones; Pregnenolone; Progesterone; Testis; Testosterone; Tritium

1998
Neurosteroid progesterone is up-regulated in the brain of jimpy and shiverer mice.
    Glia, 2000, Jan-01, Volume: 29, Issue:1

    Topics: 5-alpha-Dihydroprogesterone; Adrenal Cortex; Animals; Brain; Brain Chemistry; Corticosterone; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Demyelinating Diseases; Diazepam Binding Inhibitor; Immunohistochemistry; Leydig Cells; Male; Mice; Mice, Inbred Strains; Mice, Jimpy; Mice, Neurologic Mutants; Neuropeptides; Organ Specificity; Peptide Fragments; Pregnanediones; Pregnanolone; Pregnenolone; Progesterone; Radioimmunoassay; Receptors, Cytoplasmic and Nuclear; Up-Regulation

2000
Prolonged intracerebroventricular infusion of neurosteroids affects cognitive performances in the mouse.
    Brain research, 2000, Mar-10, Volume: 858, Issue:2

    Topics: 5-alpha-Dihydroprogesterone; Animals; Behavior, Animal; Cognition; Infusion Pumps, Implantable; Injections, Intraventricular; Male; Maze Learning; Memory; Mice; Neuroprotective Agents; Pregnanediones; Pregnanolone; Pregnenolone; Prosencephalon; Space Perception

2000
Steroidogenic correlates of pregnancy in the rock hyrax (Procavia capensis).
    Life sciences, 2001, Mar-23, Volume: 68, Issue:18

    Topics: 5-alpha-Dihydroprogesterone; Animals; Binding, Competitive; Cells, Cultured; Chromatography, High Pressure Liquid; Corpus Luteum; Erythrocytes; Female; Hyraxes; Leukocytes; Pregnancy; Pregnancy, Animal; Pregnanediones; Pregnenolone; Progesterone; Receptors, Progesterone

2001
Neuroactive ring A-reduced metabolites of progesterone in human plasma during pregnancy: elevated levels of 5 alpha-dihydroprogesterone in depressed patients during the latter half of pregnancy.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:12

    Topics: 5-alpha-Dihydroprogesterone; Adult; Blood; Depression; Female; Humans; Pregnancy; Pregnancy Complications; Pregnancy Trimester, Second; Pregnancy Trimester, Third; Pregnanediones; Pregnenolone; Progesterone

2001
Modulation of the firing activity of female dorsal raphe nucleus serotonergic neurons by neuroactive steroids.
    The Journal of endocrinology, 2004, Volume: 182, Issue:1

    Topics: 5-alpha-Dihydroprogesterone; Animals; Anisoles; Antipsychotic Agents; Dehydroepiandrosterone; Dihydrotestosterone; Female; Finasteride; Gender Identity; Gonadal Steroid Hormones; Neurons; Ovariectomy; Pregnenolone; Progesterone; Propylamines; Protein Isoforms; Raphe Nuclei; Rats; Rats, Sprague-Dawley; Receptors, sigma; Serotonin; Synaptic Transmission; Time Factors

2004
3alpha-reduced neuroactive steroids and their precursors during pregnancy and the postpartum period.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2005, Volume: 21, Issue:5

    Topics: 5-alpha-Dihydroprogesterone; Adult; Delivery, Obstetric; Depression, Postpartum; Female; Gas Chromatography-Mass Spectrometry; Gestational Age; Humans; Labor Onset; Parity; Postpartum Period; Pregnancy; Pregnanolone; Pregnenolone; Progesterone

2005
Injury elicited increase in spinal cord neurosteroid content analyzed by gas chromatography mass spectrometry.
    Endocrinology, 2006, Volume: 147, Issue:4

    Topics: 17-Hydroxysteroid Dehydrogenases; 5-alpha-Dihydroprogesterone; Animals; Cholesterol Side-Chain Cleavage Enzyme; Gas Chromatography-Mass Spectrometry; Male; Pregnanolone; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Spinal Cord; Spinal Cord Injuries

2006
Progesterone metabolism in bovine endometrial cells and the effect of metabolites on the responsiveness of the cells to OT-stimulation of PGF2alpha.
    Steroids, 2007, Volume: 72, Issue:13

    Topics: 5-alpha-Dihydroprogesterone; Animals; Cattle; Chromatography, High Pressure Liquid; Dinoprost; Endometrium; Female; Oxytocin; Pregnenolone; Progesterone; Receptors, Oxytocin; Stromal Cells

2007
Low levels of progesterone and derivatives in cerebrospinal fluid of patients affected by status epilepticus.
    Journal of neurochemistry, 2018, Volume: 147, Issue:2

    Topics: 5-alpha-Dihydroprogesterone; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Pregnanolone; Pregnenolone; Progesterone; Retrospective Studies; Status Epilepticus; Steroids; Tandem Mass Spectrometry; Young Adult

2018
Steroid profiles in quail brain and serum: Sex and regional differences and effects of castration with steroid replacement.
    Journal of neuroendocrinology, 2019, Volume: 31, Issue:2

    Topics: 20-alpha-Dihydroprogesterone; 5-alpha-Dihydroprogesterone; Animals; Brain; Castration; Corticosterone; Estrogens; Female; Hypothalamus; Male; Pregnenolone; Preoptic Area; Quail; Sex Characteristics; Steroids; Testosterone

2019
Augmentation of endogenous neurosteroid synthesis alters experimental status epilepticus dynamics.
    Epilepsia, 2020, Volume: 61, Issue:9

    Topics: 5-alpha-Dihydroprogesterone; Animals; Brain; Chromatography, Liquid; Dihydrotestosterone; Electrocorticography; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Hippocampus; Kainic Acid; Male; Neocortex; Neurosteroids; Pregnanolone; Pregnenolone; Progesterone; Rats; Receptors, GABA-A; Status Epilepticus; Tandem Mass Spectrometry; Time Factors

2020
BV-2 Microglial Cells Respond to Rotenone Toxic Insult by Modifying Pregnenolone, 5α-Dihydroprogesterone and Pregnanolone Levels.
    Cells, 2020, 09-13, Volume: 9, Issue:9

    Topics: 5-alpha-Dihydroprogesterone; Animals; Cell Line, Transformed; Cell Survival; Chromatography, Liquid; Mice; Microglia; Pregnanolone; Pregnenolone; Reactive Oxygen Species; Rotenone; Signal Transduction; Tandem Mass Spectrometry

2020