Page last updated: 2024-09-02

5-acetylamino-6-formylamino-3-methyluracil and uric acid

5-acetylamino-6-formylamino-3-methyluracil has been researched along with uric acid in 17 studies

Compound Research Comparison

Studies
(5-acetylamino-6-formylamino-3-methyluracil)
Trials
(5-acetylamino-6-formylamino-3-methyluracil)
Recent Studies (post-2010)
(5-acetylamino-6-formylamino-3-methyluracil)
Studies
(uric acid)
Trials
(uric acid)
Recent Studies (post-2010) (uric acid)
532527,9801,7179,982

Protein Interaction Comparison

ProteinTaxonomy5-acetylamino-6-formylamino-3-methyluracil (IC50)uric acid (IC50)
Solute carrier family 2, facilitated glucose transporter member 9Homo sapiens (human)300

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19901 (5.88)18.7374
1990's4 (23.53)18.2507
2000's8 (47.06)29.6817
2010's4 (23.53)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Campbell, ME; Kalow, W; Spielberg, SP1
Galteau, MM; Gueguen, R; Pontes, ZB; Siest, G; Vincent-Viry, M1
Bernal, ML; Fanlo, A; Juste, JL; Lanuza, J; Mayayo, E; Sáenz, MA; Sinués, B1
Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT1
Cao, XM; Lin, SS; Lu, JF; Yi, T; Zhuo, HT1
Abraham, K; Bauer, S; Brockmöller, J; Geusau, A; Helge, H; Tosun, Y1
Borlak, J; Cascorbi, I; Erb, K; Fuhr, U; Hermann, R; Illauer, M; Jetter, A; Kinzig-Schippers, M; Smith, G; Sörgel, F; Wolf, H1
Li, J; Peng, XQ; Xu, JP; Zhang, J1
Brüning, T; John, A; Rihs, HP; Scherenberg, M; Seidel, A1
Brøsen, K; Damkier, P; Grandjean, P; Halling, J; Nielsen, F; Petersen, MS; Weihe, P1
Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A1
Fuhr, U; Jetter, A; Kinzig, M; Rodamer, M; Sörgel, F; Tomalik-Scharte, D1
Ashida, H; Hashimoto, T; Kanazawa, K; Nakabayashi, H; Nishiumi, S1
Aklillu, E; Carrillo, JA; Djordjevic, N; Fukasawa, T; Gervasini, G; Jankovic, S; Suda, A; Ueda, N1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Karlsson, S; Roh, HK; Ueda, N1
Fan, XR; Li, XY; Li, YF; Li, YP; Liu, YN; Yang, M; Yao, XC; Yin, YM; Yuan, M; Zhu, JB1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Makonnen, E1

Other Studies

17 other study(ies) available for 5-acetylamino-6-formylamino-3-methyluracil and uric acid

ArticleYear
A urinary metabolite ratio that reflects systemic caffeine clearance.
    Clinical pharmacology and therapeutics, 1987, Volume: 42, Issue:2

    Topics: Adult; Age Factors; Asian People; Caffeine; Child; Child, Preschool; Contraceptives, Oral; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Smoking; Time Factors; Uracil; Uric Acid; White People; Xanthines

1987
Segregation analyses of four urinary caffeine metabolite ratios implicated in the determination of human acetylation phenotypes.
    Genetic epidemiology, 1994, Volume: 11, Issue:2

    Topics: Acetylation; Adolescent; Adult; Alleles; Arylamine N-Acetyltransferase; Caffeine; Child; Chromatography, High Pressure Liquid; Family; Female; Gene Frequency; Genes, Recessive; Humans; Male; Middle Aged; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Genetic; Theophylline; Uracil; Uric Acid; Xanthines

1994
Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenicity and urine flow.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1999, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Environmental Exposure; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mutagens; Rheology; Smoking; Theophylline; Time Factors; Uracil; Uric Acid; Urination; Xanthines

1999
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

1997
[HPLC determination of five caffeine metabolites].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:8

    Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Theophylline; Uracil; Uric Acid; Xanthines

1997
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction.
    Clinical pharmacology and therapeutics, 2002, Volume: 72, Issue:2

    Topics: Adult; Breath Tests; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Enzyme Induction; Female; Humans; Liver; Male; Methylation; Polychlorinated Dibenzodioxins; Smoking; Teratogens; Theophylline; Uracil; Uric Acid; Xanthines

2002
Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure.
    European journal of clinical pharmacology, 2004, Volume: 60, Issue:1

    Topics: Acetylation; Administration, Oral; Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Diet; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Spectrometry, Mass, Electrospray Ionization; Time Factors; Uracil; Uric Acid; Xanthines

2004
[Determination of the activity of cytochrome P-450 CYP2A6 by HPLC method with caffeine as metabolizing probe].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2006, Volume: 41, Issue:3

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Female; Humans; Male; Mixed Function Oxygenases; Theophylline; Uracil; Uric Acid; Xanthines

2006
Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay.
    Clinica chimica acta; international journal of clinical chemistry, 2007, Volume: 376, Issue:1-2

    Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Genotype; Humans; Male; Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Uracil; Uric Acid; White People; Xanthines

2007
Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls.
    European journal of clinical pharmacology, 2006, Volume: 62, Issue:12

    Topics: Administration, Oral; Adolescent; Adult; Biometry; Caffeine; Cohort Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Female; Genotype; Humans; Male; Methylation; Middle Aged; Polychlorinated Biphenyls; Sex Factors; Smoking; Uracil; Uric Acid; Xanthines

2006
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:2

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

2007
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:4

    Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Humans; Male; Phenotype; Time Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines

2009
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes.
    BioFactors (Oxford, England), 2008, Volume: 34, Issue:4

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Biological Transport; Caffeine; Cell Differentiation; Glucose; Insulin; Lipid Metabolism; Mice; Theophylline; Uracil; Uric Acid; Xanthines

2008
N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:7

    Topics: Acetylation; Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Female; Genetic Association Studies; Haplotypes; Humans; Isoenzymes; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Serbia; Uracil; Uric Acid; White People; Xanthines; Young Adult

2011
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:10

    Topics: Arylamine N-Acetyltransferase; Asian People; Caffeine; Contraceptives, Oral; Genotype; Humans; Phenotype; Polymorphism, Single Nucleotide; Sex Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines

2012
[Effect of Tibetan medicine zuotai on the activity, protein and mRNA expression of CYP1A2 and NAT2].
    Yao xue xue bao = Acta pharmaceutica Sinica, 2014, Volume: 49, Issue:2

    Topics: Administration, Oral; Animals; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Male; Medicine, Tibetan Traditional; Rats; Rats, Sprague-Dawley; RNA, Messenger; Theophylline; Uracil; Uric Acid; Xanthines

2014
N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.
    European journal of clinical pharmacology, 2018, Volume: 74, Issue:7

    Topics: Adult; Arylamine N-Acetyltransferase; Black People; Caffeine; Ethiopia; Female; Gene-Environment Interaction; Genotype; Humans; Male; Phenotype; Polymorphism, Single Nucleotide; Sweden; Uracil; Uric Acid; Xanthines

2018