5-acetylamino-6-formylamino-3-methyluracil has been researched along with caffeine in 45 studies
Studies (5-acetylamino-6-formylamino-3-methyluracil) | Trials (5-acetylamino-6-formylamino-3-methyluracil) | Recent Studies (post-2010) (5-acetylamino-6-formylamino-3-methyluracil) | Studies (caffeine) | Trials (caffeine) | Recent Studies (post-2010) (caffeine) |
---|---|---|---|---|---|
53 | 2 | 5 | 25,501 | 2,393 | 6,825 |
Protein | Taxonomy | 5-acetylamino-6-formylamino-3-methyluracil (IC50) | caffeine (IC50) |
---|---|---|---|
Acetylcholinesterase | Homo sapiens (human) | 7.25 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (24.44) | 18.7374 |
1990's | 15 (33.33) | 18.2507 |
2000's | 14 (31.11) | 29.6817 |
2010's | 4 (8.89) | 24.3611 |
2020's | 1 (2.22) | 2.80 |
Authors | Studies |
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Ebihara, A; Hashiguchi, M | 1 |
Kalow, W; Tang, BK | 1 |
Chan, MM; Kou, M; Kumana, CR; Lauder, IJ; Wong, KL; Wong, RW | 1 |
Butler, MA; Kadlubar, FF; Lang, NP; Massengill, JP; Talaska, G; Teitel, CH | 1 |
Chaleby, K; el-Yazigi, A; Martin, CR | 1 |
Hildebrand, M; Seifert, W | 1 |
Badoual, J; Carrier, O; Moran, C; Olive, G; Pons, G; Rey, E; Richard, MO | 2 |
Lorenzo, B; Reidenberg, MM | 1 |
Bartle, WR; Hardy, BG; Lemieux, C; Walker, SE | 1 |
Dayer, P; Gascon, MP; Leemann, T | 1 |
Campbell, ME; Kalow, W; Spielberg, SP | 1 |
Kadar, D; Kalow, W; Tang, BK | 1 |
Grant, DM; Kalow, W; Tang, BK | 2 |
Arvela, P; Klebovich, I; Pelkonen, O; Rautio, A; Salonpää, P; Sotaniemi, EA | 1 |
Bresnick, E; McQuilkin, SH; Nierenberg, DW | 1 |
Cribb, AE; Gillespie, CT; Isbrucker, R; Levatte, T; Renton, KW; Tsui, B | 1 |
Gee, RL; Kloth, MT; Messing, EM; Swaminathan, S | 1 |
Galteau, MM; Gueguen, R; Pontes, ZB; Siest, G; Vincent-Viry, M | 1 |
Bell, DA; Brubaker, LH; Butler, MA; Kadlubar, FF; Lucier, GW; Stephens, EA; Taylor, JA; Wiest, J | 1 |
Arvela, P; Klebovich, I; Pelkonen, O | 1 |
Bechtel, PR; Bechtel, YC; Bonaiti-Pellie, C; Magnette, J; Poisson, N | 1 |
Bernal, ML; Fanlo, A; Juste, JL; Lanuza, J; Mayayo, E; Sáenz, MA; Sinués, B | 1 |
Bechtel, PR; Bechtel, YC; Brientini, MP; Hrusovsky, S; Lelouët, H; Mantion, G; Miguet, JP; Paintaud, G | 1 |
Banerjee, K; Lang, N; Leyland-Jones, B; Massengill, J; Nowell, S; Wong, P | 1 |
Biollaz, J; Décosterd, LA; Kesselring, UW; Nyéki, A | 1 |
Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT | 1 |
Cao, XM; Lin, SS; Lu, JF; Yi, T; Zhuo, HT | 1 |
Cui, X; Guo, R; Li, C; Wang, B; Xu, Z | 1 |
Abraham, K; Bauer, S; Brockmöller, J; Geusau, A; Helge, H; Tosun, Y | 1 |
Biollaz, J; Buclin, T; Decosterd, LA; Nyéki, A | 1 |
Borlak, J; Cascorbi, I; Erb, K; Fuhr, U; Hermann, R; Illauer, M; Jetter, A; Kinzig-Schippers, M; Smith, G; Sörgel, F; Wolf, H | 1 |
Blaszkewicz, M; Bolt, HM; Dannappel, D; Golka, K; Selinski, S | 1 |
Li, J; Peng, XQ; Xu, JP; Zhang, J | 1 |
Brüning, T; John, A; Rihs, HP; Scherenberg, M; Seidel, A | 1 |
Brøsen, K; Damkier, P; Grandjean, P; Halling, J; Nielsen, F; Petersen, MS; Weihe, P | 1 |
Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A | 1 |
Fuhr, U; Jetter, A; Kinzig, M; Rodamer, M; Sörgel, F; Tomalik-Scharte, D | 1 |
Ashida, H; Hashimoto, T; Kanazawa, K; Nakabayashi, H; Nishiumi, S | 1 |
Aklillu, E; Carrillo, JA; Djordjevic, N; Fukasawa, T; Gervasini, G; Jankovic, S; Suda, A; Ueda, N | 1 |
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Karlsson, S; Roh, HK; Ueda, N | 1 |
Fan, XR; Li, XY; Li, YF; Li, YP; Liu, YN; Yang, M; Yao, XC; Yin, YM; Yuan, M; Zhu, JB | 1 |
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Makonnen, E | 1 |
Au, PCM; Chau, YP; Cheng, VKF; Cheung, CL; Kung, AWC; Li, GHY; Sing, CW; Tan, KCB | 1 |
1 trial(s) available for 5-acetylamino-6-formylamino-3-methyluracil and caffeine
Article | Year |
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Antipyrine, coumarin and glipizide affect n-acetylation measured by caffeine test.
Topics: Acetylation; Adult; Analysis of Variance; Antipyrine; Caffeine; Coumarins; Diabetes Mellitus, Type 2; Female; Glipizide; Humans; Hypoglycemic Agents; Male; Middle Aged; Uracil; Xanthines | 1995 |
44 other study(ies) available for 5-acetylamino-6-formylamino-3-methyluracil and caffeine
Article | Year |
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Acetylation polymorphism of caffeine in a Japanese population.
Topics: Acetylation; Adult; Caffeine; Humans; Japan; Male; Metabolism; Phenotype; Polymorphism, Genetic; Uracil; Xanthines | 1992 |
Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities.
Topics: Adult; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Ethanol; Female; Humans; Longitudinal Studies; Male; Uracil; Xanthine Oxidase | 1991 |
Lack of association between slow acetylator status and spontaneous lupus erythematosus.
Topics: Acetylation; Adult; Caffeine; China; Chromatography, High Pressure Liquid; Female; Humans; Lupus Erythematosus, Systemic; Phenotype; Uracil; Xanthines | 1990 |
Determination of carcinogenic arylamine N-oxidation phenotype in humans by analysis of caffeine urinary metabolites.
Topics: Acetylation; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Cytochrome P-450 Enzyme System; Disease Susceptibility; Humans; Isoenzymes; Oxidation-Reduction; Phenotype; Theophylline; Uracil; Urinary Bladder Neoplasms; Xanthines | 1990 |
A simplified and rapid test for acetylator phenotyping by use of the peak height ratio of two urinary caffeine metabolites.
Topics: Acetylation; Acetyltransferases; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Sulfasalazine; Uracil; Xanthines | 1989 |
Determination of acetylator phenotype in Caucasians with caffeine.
Topics: Acetylation; Adolescent; Adult; Aged; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Sex Factors; Smoking; Uracil; White People; Xanthines | 1989 |
Maturation of AFMU excretion in infants.
Topics: Acetylation; Caffeine; Chromatography, High Pressure Liquid; Humans; Indicators and Reagents; Infant; Infant, Newborn; Infant, Premature; Phenotype; Uracil | 1989 |
Potential artifacts in the use of caffeine to determine acetylation phenotype.
Topics: Acetylation; Caffeine; False Positive Reactions; Humans; Phenotype; Time Factors; Uracil; Xanthines | 1989 |
Maturation of caffeine metabolic pathways in infancy.
Topics: Acetylation; Administration, Oral; Adult; Age Factors; Apnea; Caffeine; Chromatography, High Pressure Liquid; Citrates; Drug Combinations; Female; Humans; Hydroxylation; Infant; Infant, Newborn; Infant, Premature; Male; Pierre Robin Syndrome; Time Factors; Uracil; Xanthines | 1988 |
Interindividual and intraindividual variability in acetylation: characterization with caffeine.
Topics: Acetylation; Acetyltransferases; Adult; Caffeine; Chromatography, High Pressure Liquid; Female; Humans; Male; Phenotype; Time Factors; Uracil; Xanthines | 1988 |
[Evaluation of a caffeine test for determining the phenotype of N-acetyltransferase].
Topics: Acetyltransferases; Caffeine; Chromatography, High Pressure Liquid; Humans; In Vitro Techniques; Liver; Microsomes, Liver; Phenotype; Polymorphism, Genetic; Uracil | 1987 |
A urinary metabolite ratio that reflects systemic caffeine clearance.
Topics: Adult; Age Factors; Asian People; Caffeine; Child; Child, Preschool; Contraceptives, Oral; Cytochrome P-450 Enzyme System; Female; Humans; Kinetics; Male; Metabolic Clearance Rate; Middle Aged; Smoking; Time Factors; Uracil; Uric Acid; White People; Xanthines | 1987 |
An alternative test for acetylator phenotyping with caffeine.
Topics: Acetylation; Caffeine; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Humans; Longitudinal Studies; Male; Methods; Phenotype; Time Factors; Uracil | 1987 |
A simple test for acetylator phenotype using caffeine.
Topics: Acetylation; Acetyltransferases; Adolescent; Adult; Aged; Caffeine; Chemistry, Organic; Child; Child, Preschool; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans; Middle Aged; Organic Chemistry Phenomena; Phenotype; Sulfamethazine; Uracil; Xanthines | 1984 |
Polymorphic N-acetylation of a caffeine metabolite.
Topics: Acetylation; Acetyltransferases; Adolescent; Adult; Aged; Asian People; Caffeine; Chromatography, High Pressure Liquid; Female; Humans; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Sulfamethazine; Uracil; White People | 1983 |
Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities.
Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; Female; Genetic Variation; Humans; Male; Middle Aged; Oxidoreductases; Phenotype; Spectrophotometry, Ultraviolet; Theophylline; Time Factors; Uracil; Xanthines | 1995 |
Acetylator phenotyping: the urinary caffeine metabolite ratio in slow acetylators correlates with a marker of systemic NAT1 activity.
Topics: 4-Aminobenzoic Acid; Acetylation; Adult; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Female; Humans; Isoenzymes; Kinetics; Leukocytes, Mononuclear; Male; Middle Aged; Phenotype; Substrate Specificity; Uracil; Xanthines | 1994 |
Expression of N-acetyltransferase (NAT) in cultured human uroepithelial cells.
Topics: Acetylation; Adult; Alleles; Amines; Arylamine N-Acetyltransferase; Biomarkers; Caffeine; Cells, Cultured; Cytochrome P-450 CYP1A2; Cytochrome P-450 Enzyme System; DNA, Complementary; Epithelial Cells; Epithelium; Female; Gene Expression; Genetic Predisposition to Disease; Humans; Male; Microsomes, Liver; Oxidoreductases; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Risk Factors; Uracil; Ureter; Urinary Bladder Neoplasms; Xanthines | 1994 |
Segregation analyses of four urinary caffeine metabolite ratios implicated in the determination of human acetylation phenotypes.
Topics: Acetylation; Adolescent; Adult; Alleles; Arylamine N-Acetyltransferase; Caffeine; Child; Chromatography, High Pressure Liquid; Family; Female; Gene Frequency; Genes, Recessive; Humans; Male; Middle Aged; Models, Genetic; Models, Statistical; Phenotype; Polymorphism, Genetic; Theophylline; Uracil; Uric Acid; Xanthines | 1994 |
Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans.
Topics: Acetylation; Alleles; Amino Acid Sequence; Arylamine N-Acetyltransferase; Base Sequence; Black People; Caffeine; Genotype; Humans; Molecular Sequence Data; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Sequence Homology, Amino Acid; United States; Uracil; Xanthines | 1993 |
HPLC method for rapid determination of acetylator phenotype by measuring urinary caffeine metabolites.
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Phenotype; Reproducibility of Results; Uracil; Xanthines | 1993 |
A population and family study of N-acetyltransferase using caffeine urinary metabolites.
Topics: Acetylation; Arylamine N-Acetyltransferase; Caffeine; Family; Heterozygote; Humans; Models, Statistical; Time Factors; Uracil; Xanthines | 1993 |
Five caffeine metabolite ratios to measure tobacco-induced CYP1A2 activity and their relationships with urinary mutagenicity and urine flow.
Topics: Adolescent; Adult; Caffeine; Central Nervous System Stimulants; Cytochrome P-450 CYP1A2; Environmental Exposure; Female; Follow-Up Studies; Humans; Male; Middle Aged; Mutagens; Rheology; Smoking; Theophylline; Time Factors; Uracil; Uric Acid; Urination; Xanthines | 1999 |
Caffeine metabolism before and after liver transplantation.
Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Azathioprine; Caffeine; Case-Control Studies; Cyclosporine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Humans; Immunosuppressive Agents; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Mixed Function Oxygenases; Reference Values; Uracil; Xanthine Oxidase | 2001 |
Validity of an ELISA for N-acetyltransferase-2 (NAT2) phenotyping.
Topics: Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Genotype; Humans; Phenotype; Uracil; Xanthines | 2001 |
Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment.
Topics: Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Humans; Models, Chemical; Reproducibility of Results; Uracil; Xanthine Oxidase | 2001 |
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities].
Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines | 1997 |
[HPLC determination of five caffeine metabolites].
Topics: Caffeine; Chromatography, High Pressure Liquid; Humans; Theophylline; Uracil; Uric Acid; Xanthines | 1997 |
Relationship between metabolic phenotype of N-acetylation and bladder cancer.
Topics: Acetylation; Adult; Caffeine; Female; Humans; Male; Middle Aged; Phenotype; Uracil; Urinary Bladder Neoplasms; Xanthines | 2000 |
Severe 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) intoxication: insights into the measurement of hepatic cytochrome P450 1A2 induction.
Topics: Adult; Breath Tests; Caffeine; Case-Control Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Enzyme Induction; Female; Humans; Liver; Male; Methylation; Polychlorinated Dibenzodioxins; Smoking; Teratogens; Theophylline; Uracil; Uric Acid; Xanthines | 2002 |
NAT2 and CYP1A2 phenotyping with caffeine: head-to-head comparison of AFMU vs. AAMU in the urine metabolite ratios.
Topics: Adult; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Phenotype; Uracil | 2003 |
Phenotyping of N-acetyltransferase type 2 by caffeine from uncontrolled dietary exposure.
Topics: Acetylation; Administration, Oral; Adult; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Diet; Female; Genotype; Humans; Male; Middle Aged; Phenotype; Spectrometry, Mass, Electrospray Ionization; Time Factors; Uracil; Uric Acid; Xanthines | 2004 |
Re-investigation of the concordance of human NAT2 phenotypes and genotypes.
Topics: Acetylation; Alleles; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Genotype; Humans; Phenotype; Reverse Transcriptase Polymerase Chain Reaction; Uracil; Xanthines | 2005 |
[Determination of the activity of cytochrome P-450 CYP2A6 by HPLC method with caffeine as metabolizing probe].
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2A6; Female; Humans; Male; Mixed Function Oxygenases; Theophylline; Uracil; Uric Acid; Xanthines | 2006 |
Concordance between the deduced acetylation status generated by high-speed: real-time PCR based NAT2 genotyping of seven single nucleotide polymorphisms and human NAT2 phenotypes determined by a caffeine assay.
Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Biotransformation; Caffeine; Genotype; Humans; Male; Middle Aged; Phenotype; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Uracil; Uric Acid; White People; Xanthines | 2007 |
Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls.
Topics: Administration, Oral; Adolescent; Adult; Biometry; Caffeine; Cohort Studies; Cytochrome P-450 CYP1A2; Environmental Pollutants; Female; Genotype; Humans; Male; Methylation; Middle Aged; Polychlorinated Biphenyls; Sex Factors; Smoking; Uracil; Uric Acid; Xanthines | 2006 |
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines | 2007 |
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?
Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Humans; Male; Phenotype; Time Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines | 2009 |
Inhibitory effects of caffeine and its metabolites on intracellular lipid accumulation in murine 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Anti-Obesity Agents; Biological Transport; Caffeine; Cell Differentiation; Glucose; Insulin; Lipid Metabolism; Mice; Theophylline; Uracil; Uric Acid; Xanthines | 2008 |
N-Acetyltransferase-2 (NAT2) gene polymorphisms and enzyme activity in Serbs: unprecedented high prevalence of rapid acetylators in a White population.
Topics: Acetylation; Adolescent; Adult; Arylamine N-Acetyltransferase; Caffeine; Female; Genetic Association Studies; Haplotypes; Humans; Isoenzymes; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Serbia; Uracil; Uric Acid; White People; Xanthines; Young Adult | 2011 |
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans.
Topics: Arylamine N-Acetyltransferase; Asian People; Caffeine; Contraceptives, Oral; Genotype; Humans; Phenotype; Polymorphism, Single Nucleotide; Sex Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines | 2012 |
[Effect of Tibetan medicine zuotai on the activity, protein and mRNA expression of CYP1A2 and NAT2].
Topics: Administration, Oral; Animals; Arylamine N-Acetyltransferase; Caffeine; Cytochrome P-450 CYP1A2; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Female; Male; Medicine, Tibetan Traditional; Rats; Rats, Sprague-Dawley; RNA, Messenger; Theophylline; Uracil; Uric Acid; Xanthines | 2014 |
N-Acetyltransferase-2 (NAT2) phenotype is influenced by genotype-environment interaction in Ethiopians.
Topics: Adult; Arylamine N-Acetyltransferase; Black People; Caffeine; Ethiopia; Female; Gene-Environment Interaction; Genotype; Humans; Male; Phenotype; Polymorphism, Single Nucleotide; Sweden; Uracil; Uric Acid; Xanthines | 2018 |
Serum Metabolome of Coffee Consumption and its Association With Bone Mineral Density: The Hong Kong Osteoporosis Study.
Topics: Absorptiometry, Photon; Alkaloids; Bone Density; Caffeine; Coffee; Diet Surveys; Drinking; Female; Femur Neck; Hippurates; Hong Kong; Humans; Independent Living; Linear Models; Lumbar Vertebrae; Male; Metabolome; Middle Aged; Osteoporosis; Prospective Studies; Uracil | 2020 |