Page last updated: 2024-09-02

5-acetylamino-6-formylamino-3-methyluracil and allopurinol

5-acetylamino-6-formylamino-3-methyluracil has been researched along with allopurinol in 7 studies

Compound Research Comparison

Studies
(5-acetylamino-6-formylamino-3-methyluracil)
Trials
(5-acetylamino-6-formylamino-3-methyluracil)
Recent Studies (post-2010)
(5-acetylamino-6-formylamino-3-methyluracil)
Studies
(allopurinol)
Trials
(allopurinol)
Recent Studies (post-2010) (allopurinol)
532515,0967433,363

Protein Interaction Comparison

ProteinTaxonomy5-acetylamino-6-formylamino-3-methyluracil (IC50)allopurinol (IC50)
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase Rattus norvegicus (Norway rat)3.3765
Xanthine dehydrogenase/oxidaseHomo sapiens (human)3.1861
Xanthine dehydrogenase/oxidaseBos taurus (cattle)5.0758
Histamine H3 receptorCavia porcellus (domestic guinea pig)8.69

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's4 (57.14)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kalow, W; Tang, BK1
Bechtel, PR; Bechtel, YC; Brientini, MP; Hrusovsky, S; Lelouët, H; Mantion, G; Miguet, JP; Paintaud, G1
Biollaz, J; Décosterd, LA; Kesselring, UW; Nyéki, A1
Cao, XM; Ling, SS; Lu, JF; Yi, T; Zhuo, HT1
Asprodini, EK; Begas, E; Kouvaras, E; Papakosta, S; Tsakalof, A1
Fuhr, U; Jetter, A; Kinzig, M; Rodamer, M; Sörgel, F; Tomalik-Scharte, D1
Aklillu, E; Bertilsson, L; Carrillo, JA; Djordjevic, N; Karlsson, S; Roh, HK; Ueda, N1

Other Studies

7 other study(ies) available for 5-acetylamino-6-formylamino-3-methyluracil and allopurinol

ArticleYear
Use of caffeine metabolite ratios to explore CYP1A2 and xanthine oxidase activities.
    Clinical pharmacology and therapeutics, 1991, Volume: 50, Issue:5 Pt 1

    Topics: Adult; Caffeine; Cytochrome P-450 Enzyme System; Drug Interactions; Ethanol; Female; Humans; Longitudinal Studies; Male; Uracil; Xanthine Oxidase

1991
Caffeine metabolism before and after liver transplantation.
    International journal of clinical pharmacology and therapeutics, 2001, Volume: 39, Issue:2

    Topics: Adult; Aged; Aryl Hydrocarbon Hydroxylases; Azathioprine; Caffeine; Case-Control Studies; Cyclosporine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme System; Female; Humans; Immunosuppressive Agents; Liver; Liver Function Tests; Liver Transplantation; Male; Middle Aged; Mixed Function Oxygenases; Reference Values; Uracil; Xanthine Oxidase

2001
Extractionless method for the simultaneous high-performance liquid chromatographic determination of urinary caffeine metabolites for N-acetyltransferase 2, cytochrome P450 1A2 and xanthine oxidase activity assessment.
    Journal of chromatography. B, Biomedical sciences and applications, 2001, May-05, Volume: 755, Issue:1-2

    Topics: Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Humans; Models, Chemical; Reproducibility of Results; Uracil; Xanthine Oxidase

2001
[Determination of caffeine metabolite for the evaluation of N-acetyltransferase, CYP1A2 and xanthine oxidase activities].
    Yao xue xue bao = Acta pharmaceutica Sinica, 1997, Volume: 32, Issue:11

    Topics: Adolescent; Adult; Aged; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Female; Humans; Male; Middle Aged; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

1997
In vivo evaluation of CYP1A2, CYP2A6, NAT-2 and xanthine oxidase activities in a Greek population sample by the RP-HPLC monitoring of caffeine metabolic ratios.
    Biomedical chromatography : BMC, 2007, Volume: 21, Issue:2

    Topics: Adult; Aryl Hydrocarbon Hydroxylases; Arylamine N-Acetyltransferase; Caffeine; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2A6; Female; Humans; Male; Middle Aged; Mixed Function Oxygenases; Reproducibility of Results; Sensitivity and Specificity; Smoking; Theophylline; Uracil; Uric Acid; Xanthine Oxidase; Xanthines

2007
Phenotyping of N-acetyltransferase type 2 and xanthine oxidase with caffeine: when should urine samples be collected?
    European journal of clinical pharmacology, 2009, Volume: 65, Issue:4

    Topics: Acetylation; Adult; Arylamine N-Acetyltransferase; Caffeine; Central Nervous System Stimulants; Humans; Male; Phenotype; Time Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines

2009
Comparison of N-acetyltransferase-2 enzyme genotype-phenotype and xanthine oxidase enzyme activity between Swedes and Koreans.
    Journal of clinical pharmacology, 2012, Volume: 52, Issue:10

    Topics: Arylamine N-Acetyltransferase; Asian People; Caffeine; Contraceptives, Oral; Genotype; Humans; Phenotype; Polymorphism, Single Nucleotide; Sex Factors; Uracil; Uric Acid; White People; Xanthine Oxidase; Xanthines

2012