Compounds > 5,8,11,14-eicosatetraynoic acid

5,8,11,14-eicosatetraynoic acid and pirinixic acid

5,8,11,14-eicosatetraynoic acid has been researched along with pirinixic acid in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's4 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Auwerx, J; Dallongeville, J; Fruchart, JC; Kosykh, V; Schoonjans, K; Staels, B; Vu-Dac, N1
Chawla, A; Lazar, MA1
Kockx, M; Kooistra, T; Princen, HM2
Alberts, DW; Ledwith, BJ; Manam, S; Pauley, CJ; Rokos, CL; Wagner, LK1
Devchand, PR; Keller, H; Perroud, M; Wahli, W1
Börchers, T; Sacchettini, JC; Spener, F; Wolfrum, C1
Chandraratna, RA; Fleck, E; Goetze, S; Graf, K; Hsueh, WA; Kim, S; Kintscher, U; Law, RE; Nagpal, S; Wakino, S1
Hombach, V; Libby, P; Mackman, N; Marx, N; Plutzky, J; Schönbeck, U; Yilmaz, N1
Bruemmer, D; Feng, X; Fleck, E; Goetze, S; Graf, K; Hsueh, WA; Kintscher, U; Law, RE; Lyon, C; Moustakas, A; Staels, B; Wakino, S1

Trials

1 trial(s) available for 5,8,11,14-eicosatetraynoic acid and pirinixic acid

ArticleYear
Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor.
    The Journal of clinical investigation, 1995, Volume: 96, Issue:2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Apolipoprotein A-II; Apolipoproteins E; Base Sequence; Cells, Cultured; Cholesterol, HDL; Coronary Disease; Fenofibrate; Gene Expression Regulation; Genes, Reporter; Hepatoblastoma; Humans; Liver; Liver Neoplasms; Male; Middle Aged; Molecular Sequence Data; Mutagenesis, Site-Directed; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; Regulatory Sequences, Nucleic Acid; Transcription Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured

1995

Other Studies

9 other study(ies) available for 5,8,11,14-eicosatetraynoic acid and pirinixic acid

ArticleYear
Peroxisome proliferator and retinoid signaling pathways co-regulate preadipocyte phenotype and survival.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Mar-01, Volume: 91, Issue:5

    Topics: 3T3 Cells; 5,8,11,14-Eicosatetraynoic Acid; Adipose Tissue; Animals; Apoptosis; Cell Survival; Clofibrate; Culture Media; Mice; Microbodies; Phenotype; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Signal Transduction; Stem Cells; Transcription Factors; Tretinoin

1994
Studies on the role of PPAR in the fibrate-modulated gene expression of apolipoprotein A-I, plasminogen activator inhibitor 1, and fibrinogen in primary hepatocyte cultures from cynomolgus monkey.
    Annals of the New York Academy of Sciences, 1996, Dec-27, Volume: 804

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Apolipoprotein A-I; Cells, Cultured; Female; Fibrinogen; Gene Expression Regulation; Hypolipidemic Agents; Macaca fascicularis; Male; Microbodies; Plasminogen Activator Inhibitor 1; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Transcription Factors

1996
Induction of cyclooxygenase-2 expression by peroxisome proliferators and non-tetradecanoylphorbol 12,13-myristate-type tumor promoters in immortalized mouse liver cells.
    The Journal of biological chemistry, 1997, Feb-07, Volume: 272, Issue:6

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Diethylhexyl Phthalate; Dinoprostone; Enzyme Induction; Indomethacin; Isoenzymes; Liver; Membrane Proteins; Mice; Prostaglandin-Endoperoxide Synthases; Pyrimidines; RNA, Messenger; Tetradecanoylphorbol Acetate

1997
PPAR alpha structure-function relationships derived from species-specific differences in responsiveness to hypolipidemic agents.
    Biological chemistry, 1997, Volume: 378, Issue:7

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Amino Acid Sequence; Animals; Humans; Hypolipidemic Agents; Mice; Microbodies; Molecular Sequence Data; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Sequence Homology, Amino Acid; Species Specificity; Structure-Activity Relationship; Transcription Factors; Xenopus

1997
Fibrate-modulated expression of fibrinogen, plasminogen activator inhibitor-1 and apolipoprotein A-I in cultured cynomolgus monkey hepatocytes -- role of the peroxisome proliferator-activated receptor-alpha.
    Thrombosis and haemostasis, 1998, Volume: 80, Issue:6

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Alitretinoin; Animals; Apolipoprotein A-I; Cells, Cultured; Clofibrate; Clofibric Acid; Dimerization; Female; Fenofibrate; Fibric Acids; Fibrinogen; Gemfibrozil; Gene Expression Regulation; Genes, Reporter; Hypolipidemic Agents; Liver; Macaca fascicularis; Male; Peroxisome Proliferators; Plasminogen Activator Inhibitor 1; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoid X Receptors; Transcription Factors; Transcriptional Activation; Tretinoin

1998
Binding of fatty acids and peroxisome proliferators to orthologous fatty acid binding proteins from human, murine, and bovine liver.
    Biochemistry, 2000, Feb-15, Volume: 39, Issue:6

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Amino Acid Sequence; Animals; Bezafibrate; Calorimetry; Carrier Proteins; Cattle; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Proteins; Fatty Acids; Humans; Ligands; Liver; Mice; Molecular Sequence Data; Myelin P2 Protein; Neoplasm Proteins; Nerve Tissue Proteins; Peroxisome Proliferators; Protein Binding; Pyrimidines; Tumor Suppressor Proteins

2000
Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes.
    European journal of pharmacology, 2000, Aug-11, Volume: 401, Issue:3

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Cell Movement; Chemokine CCL2; Chemotaxis; Chromans; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flavonoids; Humans; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Monocytes; Pyrimidines; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Retinoic Acid Receptor alpha; Rosiglitazone; Tetradecanoylphorbol Acetate; Thiazoles; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1; Transcription Factors; Troglitazone; Tumor Cells, Cultured

2000
PPARalpha activators inhibit tissue factor expression and activity in human monocytes.
    Circulation, 2001, Jan-16, Volume: 103, Issue:2

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Cells, Cultured; DNA; Humans; Lipopolysaccharides; Macrophages; Monocytes; NF-kappa B; Peroxisome Proliferators; Promoter Regions, Genetic; Proto-Oncogene Proteins c-rel; Pyrimidines; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Thromboplastin; Transcription Factor RelA; Transcription Factors; Tumor Necrosis Factor-alpha

2001
PPARalpha inhibits TGF-beta-induced beta5 integrin transcription in vascular smooth muscle cells by interacting with Smad4.
    Circulation research, 2002, Nov-29, Volume: 91, Issue:11

    Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Cell Movement; Cells, Cultured; DNA-Binding Proteins; Gene Expression; Genes, Reporter; Integrin beta Chains; Integrin beta3; Ligands; Macromolecular Substances; Muscle, Smooth, Vascular; Nuclear Proteins; Platelet-Derived Growth Factor; Promoter Regions, Genetic; Protein Binding; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; Smad4 Protein; Trans-Activators; Transcription Factors; Transcription, Genetic; Transforming Growth Factor beta

2002