5,8,11,14-eicosatetraynoic acid has been researched along with masoprocol in 112 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 68 (60.71) | 18.7374 |
| 1990's | 39 (34.82) | 18.2507 |
| 2000's | 4 (3.57) | 29.6817 |
| 2010's | 1 (0.89) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hagerman, TK; Karver, CE; Kawarski, M | 1 |
| Ek, B; Hansson, G; Johansson, M | 1 |
| Derian, CK; Lewis, DF | 1 |
| Chang, WC; Huang, JD; Lin, MT; Ning, CC | 1 |
| Grollman, EF; Kohn, LD; Saji, M; Tahara, K | 1 |
| Bedwell, S; Darley-Usmar, V; Jessup, W; O'Leary, V | 1 |
| Buller, RM; Palumbo, GJ | 1 |
| Hannigan, GE; Williams, BR | 1 |
| Kim, HY; Salem, N; Sawazaki, S | 1 |
| Shikada, K; Tanaka, S; Yamamoto, A | 1 |
| Breitbart, H; Grossman, S; Lax, Y; Magid, N; Rubinstein, S | 1 |
| Ardaillou, R; Bens, M; Guidet, B; Lacave, R; Nagamine, Y; Rondeau, E; Sraer, J; Sraer, JD | 1 |
| Bernardini, R; Calogero, AE; Chrousos, GP; Mauceri, G | 1 |
| Dray, F; Israel, JM; Junier, MP; Vincent, JD | 1 |
| Hallberg, E; Rydström, J | 1 |
| Bernardini, R; Calogero, AE; Chrousos, GP; Gold, PW; Gomez, MT; Johnson, EO; Kamilaris, TC | 1 |
| Anderson, KM; Seed, TM; Wilson, DE | 1 |
| Hamberg, G; Hamberg, M | 1 |
| Chand, N; Diamantis, W; Pillar, J; Sofia, RD | 1 |
| Anderson, KM; DiGianfilippo, A; Harris, JE; Ondrey, FG; Wilson, DE | 1 |
| Canonico, PL | 1 |
| Parthasarathy, S; Steinberg, D; Wieland, E | 1 |
| Farnam, J; Giclas, PC; Grant, JA; Hunt, C; Lett-Brown, MA; Thueson, DO | 1 |
| Chang, JP; de Leeuw, R; Freedman, GL | 1 |
| Ahmed, AM; Blachier, F; Lacroix, MC; Léger, C; Ollivier-Bousquet, M | 1 |
| Bhattacherjee, P; Boughton-Smith, NK; Follenfant, RL; Garland, LG; Higgs, GA; Hodson, HF; Islip, PJ; Jackson, WP; Moncada, S; Payne, AN | 1 |
| Clark, DL; Linden, J | 1 |
| Jondal, M; Kullman, C; Lindgren, JA; Rossi, P | 1 |
| Catt, KJ; Kiesel, L; Naor, Z; Vanderhoek, JY | 1 |
| Agrawal, R; Daniel, EE | 1 |
| Ip, MM; Leung, KH | 1 |
| Abou-Samra, AB; Aguilera, G; Catt, KJ | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 1 |
| Snider, RM | 1 |
| Hand, JM; Lewis, AJ; Schwalm, SF | 2 |
| Catt, KJ; Chang, JP; Graeter, J | 1 |
| Ishiura, S; Villee, CA; Yoshimoto, T | 1 |
| Finiasz, M; Gimeno, M; Lazzari, MA; Schattner, MA | 1 |
| Daniel, EE; Mansour, S | 1 |
| Kishore, NP; Rao, GH; White, JG | 1 |
| Dubowy, RL; Setty, BN; Stuart, MJ | 1 |
| Didolkar, AK; Sundaram, K | 1 |
| Basu, DK; Karmazyn, M | 1 |
| Baxter, CS; Lawrence, AT | 1 |
| Capdevila, J; Falck, JR; Gil, L; Marnett, LJ; Mason, JI; Orellana, M; Yadagiri, P | 1 |
| Kim, RS; LaBella, FS; Sukhu, B | 1 |
| Jackson, WF | 1 |
| Cassina, G; Livio, M; Macconi, D; Morelli, C; Morzenti, G; Remuzzi, G | 1 |
| Brashers, VL; Peach, MJ; Rose, CE | 1 |
| Knych, ET | 1 |
| Harper, MJ; Herlihy, JT; Johns, A | 1 |
| Gimeno, M; Lazzari, MA; Schattner, MA | 1 |
| Emeis, JJ; Havekes, L; van der Schroeff, JG; Vermeer, BJ; Weerheim, AM | 1 |
| Colca, J; Comens, PG; Jakschik, B; McDaniel, ML; Turk, J; Wolf, BA | 1 |
| Förstermann, U; Neufang, B | 1 |
| Cammarata, P; Pincus, SH | 1 |
| Becker, EL; Lanni, C | 1 |
| Fenton, JW; McKinney, M; Richelson, E; Snider, RM | 1 |
| Knepel, W; Vlaskovska, M | 1 |
| Casebolt, TL; Marcelo, CL; Voorhees, JJ; Ziboh, VA | 1 |
| Richelson, E; Snider, RM | 1 |
| Dorsch, W; Riepel, H; Ring, J | 1 |
| Furchgott, RF | 1 |
| Bokoch, GM; Reed, PW | 1 |
| Gorman, RR; Lin, AH; Morton, DR | 1 |
| Ford-Hutchinson, AW | 1 |
| Donnelly, RP; Rogers, TJ | 1 |
| Aharony, D; Dobson, P; Krell, RD | 1 |
| Capdevila, J; Chacos, N; Falck, JR; Manna, S; Snyder, GD | 1 |
| Clanton, JA; Colley, DG; Rand, TH | 1 |
| Crutchley, DJ; Maynard, JR | 1 |
| Mitchell, MD; Saeed, SA | 1 |
| Borda, E; Gimeno, AL; Gimeno, MF; Lazzari, MA; Shattner, MA | 1 |
| Peach, MJ; Singer, HA | 1 |
| Mueller, GC; Pai, JK; Wrighton, SA | 1 |
| Borda, E; de Bracco, MM; Finiasz, M; Fink, S; Sterin-Borda, L | 1 |
| Goossens, J; Van Wauwe, J | 1 |
| Cooke, BA; Dix, CJ; Habberfield, AD; Sullivan, MH | 1 |
| Chang, J; Cherney, ML; Lewis, AJ; Skowronek, MD | 1 |
| O'Flaherty, JT; Stimler, NP | 1 |
| Goetzl, EJ | 1 |
| Yen, SS | 1 |
| Bowman, BJ; Smith, RJ | 1 |
| Parker, CW; Udey, MC | 1 |
| Dunn, MW; Guivernau, M; Terragno, A; Terragno, NA | 1 |
| Azzi, A; O'Donnell, VB | 1 |
| Breviario, F; de Castellarnau, C; López, S; Vila, L | 1 |
| Fralix, T; Glasgow, W; Murphy, E; Steenbergen, C | 1 |
| Fanburg, BL; Hassoun, PM; Hertig, IA; Thannickal, VJ; Zulueta, JJ | 1 |
| Beck, H; De Petrocellis, L; Di Marzo, V; Lehmann, WD; Leitz, T; Stephan, M | 1 |
| Ekokoski, E; Forss, L; Matsson, M; Törnquist, K | 1 |
| Dwornik, JJ; Hilbelink, DR; Kulkarni, AP; Mitra, AK; Roy, SK | 1 |
| Bacquart, T; Drouhault, R; Roudbaraki, MM; Vacher, P | 1 |
| Lee, KS; Xu, X | 1 |
| Graier, WF; Kostner, GM; Kukovetz, WR; Simecek, S | 1 |
| Endo, T; Goto, T; Ito, E; Kiya, T; Kudo, R; Sagae, S; Watanabe, H; Yamamoto, H | 1 |
| Coleman, ES; Sartin, JL | 1 |
| Almawi, WY; Barth, CM; Lipman, ML; Saouda, MS; Stevens, AC; Strom, TB | 1 |
| Fyfe, GK; Kemp, PJ; Olver, RE | 1 |
| Evans, RL; Turner, RJ | 1 |
| Edrington, JL; Leffler, CW; Parfenova, H; Smith, JS; Zuckerman, SL | 1 |
| Damtew, B; Spagnuolo, PJ | 1 |
| Collins, DR; Davies, SN | 1 |
| Abraham, S; Clarke, SD; Jump, DB; Reedy, M; Turini, M | 1 |
| Fry, C; Gunter, DR; McMahon, CD; Sartin, JL; Steele, B | 1 |
| Lee, HK; Meng, CL; Shen, KL; Wong, PY; Yang, CY | 1 |
| Akard, L; Boswell, HS; Carlo-Stella, C; Dugan, M; Garau, D; Regazzi, E; Rizzo, MT; Rizzoli, V | 1 |
| Saxena, NC | 1 |
| Adler-Graschinsky, E; Peredo, HA | 1 |
| Chapman, KD; Noordermeer, MA; Shrestha, R; van der Stelt, M; Veldink, GA | 1 |
| Bryja, V; Hofmanová, J; Kozubík, A; Pacherník, J; Sedlácek, J; Sevcíková, S; Smarda, J; Soucek, K; Zahradnícková, E | 1 |
2 review(s) available for 5,8,11,14-eicosatetraynoic acid and masoprocol
| Article | Year |
|---|---|
The effects of a novel series of selective inhibitors of arachidonate 5-lipoxygenase on anaphylactic and inflammatory responses.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Bronchial Provocation Tests; Bronchial Spasm; Fever; Gastric Mucosa; Guinea Pigs; Humans; Hydroxamic Acids; Inflammation; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; Rats; SRS-A | 1988 |
The role of endothelium in the responses of vascular smooth muscle to drugs.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Acetylcholine; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Arachidonic Acid; Arachidonic Acids; Bradykinin; Calcimycin; Catechols; Endothelium; Histamine; Hydroquinones; Hypoxia; Masoprocol; Methylene Blue; Muscle Relaxation; Muscle, Smooth, Vascular; Prostaglandins; Quinacrine; Serotonin; Substance P; Thrombin | 1984 |
110 other study(ies) available for 5,8,11,14-eicosatetraynoic acid and masoprocol
| Article | Year |
|---|---|
Lazaroids U83836E and U74389G are potent, time-dependent inhibitors of caspase-1.
Topics: Antioxidants; Caspase 1; Caspase Inhibitors; Drug Discovery; Humans; Small Molecule Libraries | 2015 |
Production of HETEs in human neutrophils; dependence of arachidonic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Calcimycin; Dose-Response Relationship, Drug; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Kinetics; Masoprocol; Neutrophils | 1992 |
Activation of 15-lipoxygenase by low density lipoprotein in vascular endothelial cells. Relationship to the oxidative modification of low density lipoprotein.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Arachidonate 15-Lipoxygenase; Benzyl Compounds; Cells, Cultured; Copper; Copper Sulfate; Endothelium, Vascular; Enzyme Activation; Hydroxamic Acids; Hydroxyeicosatetraenoic Acids; Indomethacin; Linoleic Acid; Linoleic Acids; Lipoproteins, LDL; Lipoxygenase Inhibitors; Masoprocol; Oxidation-Reduction; Quinolines; Swine; Umbilical Veins | 1992 |
Epidermal growth factor enhances a microsomal 12-lipoxygenase activity in A431 cells.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Aspirin; Caffeic Acids; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Cycloheximide; Epidermal Growth Factor; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Mice; Microsomes; NADP; Stereoisomerism; Substrate Specificity; Tumor Cells, Cultured | 1992 |
Regulation of prostaglandin synthesis by thyrotropin, insulin or insulin-like growth factor-I, and serum in FRTL-5 rat thyroid cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Cell Line; Chromatography, High Pressure Liquid; Culture Media; Cyclic AMP; Fatty Acids, Unsaturated; Indomethacin; Insulin; Insulin-Like Growth Factor I; Kinetics; Masoprocol; Models, Biological; Phospholipids; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Thyroid Gland; Thyrotropin | 1991 |
5-Lipoxygenase is not essential in macrophage-mediated oxidation of low-density lipoprotein.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Antioxidants; Arachidonate 5-Lipoxygenase; Benzeneacetamides; Butylated Hydroxytoluene; Cells, Cultured; Endocytosis; Free Radical Scavengers; Humans; Hydroxamic Acids; Indoles; Lipoproteins, LDL; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Oxidation-Reduction | 1991 |
Inhibitors of the lipoxygenase pathway specifically block orthopoxvirus replication.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Cells, Cultured; Chick Embryo; Cowpox virus; Ectromelia virus; Electrophoresis, Polyacrylamide Gel; Lipoxygenase Inhibitors; Masoprocol; Vaccinia virus; Viral Proteins; Virus Replication | 1991 |
Signal transduction by interferon-alpha through arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Animals; Arachidonic Acid; Arachidonic Acids; Base Sequence; Cell Line; Cyclooxygenase Inhibitors; Enhancer Elements, Genetic; Enzyme Activation; Indomethacin; Interferon Type I; Lipoxygenase Inhibitors; Lysophosphatidylcholines; Masoprocol; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Phospholipases A; Phospholipases A2; Platelet-Derived Growth Factor; Second Messenger Systems; Signal Transduction; Transcription Factors; Transcription, Genetic; Transfection | 1991 |
Lipoxygenation in rat brain?
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Brain; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Hydroxyeicosatetraenoic Acids; Indomethacin; Kinetics; Lipoxygenase; Male; Masoprocol; Methoxsalen; Proadifen; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Strains | 1991 |
Arachidonate lipoxygenase inhibitors in guinea-pig isolated trachea. Effects on contractions to antigen and various agonists.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Antigens; Arachidonate Lipoxygenases; Calcimycin; Chromones; Guinea Pigs; In Vitro Techniques; Male; Masoprocol; Muscle Contraction; Pyrazoles; Receptors, Immunologic; Receptors, Leukotriene; SRS-A; Trachea | 1990 |
Role of lipoxygenase in the mechanism of acrosome reaction in mammalian spermatozoa.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acrosome; Animals; Arachidonate 15-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Calcium; Cattle; Cyclooxygenase Inhibitors; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Phosphatidylcholines; Spermatozoa | 1990 |
Nordihydroguaiaretic acid inhibits urokinase synthesis by phorbol myristate acetate-stimulated LLC-PK1 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Cell Line; Enzyme Precursors; Fatty Acids, Unsaturated; Isoquinolines; Kinetics; Masoprocol; Piperazines; Plasminogen Activators; Plasminogen Inactivators; Protein Kinase C; Pyrazoles; Tetradecanoylphorbol Acetate; Urokinase-Type Plasminogen Activator | 1990 |
Rat hypothalamic corticotropin-releasing hormone secretion in vitro is stimulated by interleukin-1 in an eicosanoid-dependent manner.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Corticotropin-Releasing Hormone; Cyclooxygenase Inhibitors; Dexamethasone; Dinoprost; Dinoprostone; Eicosanoids; Hypothalamus; Indomethacin; Interleukin-1; Lipoxygenase Inhibitors; Male; Masoprocol; Rats; Rats, Inbred Strains | 1990 |
Contribution of arachidonate metabolites to basal and thyrotropin releasing-hormone-stimulated release of prolactin from purified lactotrophs in primary culture.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Cells, Cultured; Female; Indomethacin; Lipoxygenase; Masoprocol; Membrane Lipids; Pituitary Gland, Anterior; Prolactin; Protein Kinase Inhibitors; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone | 1990 |
Influence of effectors of prostaglandin metabolism on the toxicity induced by 7-hydroxymethyl-12-methylbenz(a)anthracene in cultured rat adrenal cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; 9,10-Dimethyl-1,2-benzanthracene; Adrenal Cortex; Animals; Arachidonic Acid; Arachidonic Acids; Benzo(a)pyrene; Bradykinin; Cells, Cultured; Dexamethasone; Drug Synergism; Hydrocortisone; Masoprocol; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats | 1990 |
Interactions between tumor necrosis factor-alpha, hypothalamic corticotropin-releasing hormone, and adrenocorticotropin secretion in the rat.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adrenocorticotropic Hormone; Animals; Cells, Cultured; Corticosterone; Corticotropin-Releasing Hormone; Dexamethasone; Hypothalamus; Immune Sera; Indomethacin; Injections, Intravenous; Kinetics; Male; Masoprocol; Pituitary Gland; Rats; Rats, Inbred Strains; Tumor Necrosis Factor-alpha | 1990 |
Ultrastructural evidence for differentiation in a human glioblastoma cell line treated with inhibitors of eicosanoid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Cell Differentiation; Eicosanoids; Glial Fibrillary Acidic Protein; Glioma; Humans; Masoprocol; Microscopy, Electron; Tumor Cells, Cultured | 1990 |
Hydroperoxide-dependent epoxidation of unsaturated fatty acids in the broad bean (Vicia faba L.).
Topics: 5,8,11,14-Eicosatetraynoic Acid; Chromatography, Thin Layer; Cytosol; Epoxy Compounds; Fabaceae; Hydroxy Acids; Kinetics; Linoleic Acid; Linoleic Acids; Masoprocol; Oleic Acid; Oleic Acids; Plants, Medicinal | 1990 |
Modulation of allergic and nonallergic histamine secretion by lipoxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Calcimycin; Catechols; Fatty Acids, Unsaturated; Histamine Release; Hypersensitivity; Kinetics; Lipoxygenase Inhibitors; Masoprocol; Mast Cells; Pyrazoles; Rabbits; Rats; Rats, Inbred Strains | 1987 |
Effect of nordihydroguaiaretic acid on cultured rat and human glioma cell proliferation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Catechols; Cell Division; Cell Line; Cell Survival; DNA Replication; Glioma; Humans; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Masoprocol; Pyrazoles; Rats; Tumor Cells, Cultured; Umbelliferones | 1989 |
Angiotensin increases arachidonate metabolism in cultured anterior pituitary cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Angiotensin I; Angiotensin II; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Diglycerides; Female; Indomethacin; Kinetics; Masoprocol; Phospholipids; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Inbred Strains; Saralasin | 1989 |
A role for endothelial cell lipoxygenase in the oxidative modification of low density lipoprotein.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Aspirin; Cells, Cultured; Copper; Endothelium, Vascular; Humans; Indomethacin; Lipoproteins, LDL; Lipoxygenase; Masoprocol; Oxidation-Reduction; Rabbits; Recombinant Proteins; Superoxide Dismutase; Superoxides | 1989 |
Complement- and IgE-mediated release of histamine from basophils in vitro. V. Differential effects of drugs modulating arachidonic acid metabolism.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Basophils; Catechols; Complement C5; Complement C5a; Histamine Release; Humans; Immunoglobulin E; Indomethacin; Masoprocol; Phospholipases; Pyrazoles | 1985 |
Participation of arachidonic acid metabolism in gonadotropin-releasing hormone stimulation of goldfish gonadotropin release.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Cells, Cultured; Cyprinidae; Goldfish; Gonadotropins, Pituitary; Indomethacin; Injections, Intraperitoneal; Masoprocol; Pituitary Gland; Pituitary Hormone-Releasing Hormones | 1989 |
Arachidonic acid metabolism and casein secretion in lactating rabbit mammary epithelial cells: effects of inhibitors of prostaglandins and leukotrienes synthesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Caseins; Cyclooxygenase Inhibitors; Dinoprost; Docosahexaenoic Acids; Epithelium; Female; Glutathione Transferase; Indomethacin; Lactation; Leukotriene B4; Lipoxygenase Inhibitors; Mammary Glands, Animal; Masoprocol; Pregnancy; Prolactin; Prostaglandins F; Rabbits; SRS-A | 1988 |
Modulation of guanylate cyclase by lipoxygenase inhibitors.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Catechols; Dogs; Fatty Acids, Unsaturated; Guanylate Cyclase; Lipoxygenase Inhibitors; Masoprocol; Methylene Blue; Muscle, Smooth, Vascular; Nitric Oxide; Vasodilator Agents | 1986 |
Second messenger function of arachidonic acid lipoxygenation products in human natural killer cell lysis?
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Catechols; Cyclic AMP; Cyclic GMP; Cytotoxicity, Immunologic; Humans; Indomethacin; Killer Cells, Natural; Lipoxygenase; Masoprocol; Pyrazoles | 1985 |
Mechanism of action of gonadotropin releasing hormone: role of lipoxygenase products of arachidonic acid in luteinizing hormone release.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Cells, Cultured; Gonadotropin-Releasing Hormone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Luteinizing Hormone; Masoprocol; Pituitary Gland; Pyrazoles; Rats; SRS-A | 1985 |
Control of gap junction formation in canine trachea by arachidonic acid metabolites.
Topics: 4-Aminopyridine; 5,8,11,14-Eicosatetraynoic Acid; Aminopyridines; Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Carbachol; Catechols; Chromones; Dinoprostone; Dogs; Epoprostenol; Female; Indomethacin; Intercellular Junctions; Male; Masoprocol; Microscopy, Electron; Prostaglandins E; Serotonin; Trachea | 1986 |
Regulation of rat natural killing. II. Inhibition of cytolysis and activation by inhibitors of lipoxygenase: possible role of leukotrienes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Cytotoxicity, Immunologic; Female; Killer Cells, Natural; Leukotriene B4; Lymphocyte Activation; Masoprocol; Phenanthrolines; Quercetin; Rats; Rats, Inbred WF; Spleen; SRS-A | 1986 |
Role of arachidonic acid in the regulation of adrenocorticotropin release from rat anterior pituitary cell cultures.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adrenocorticotropic Hormone; Animals; Arachidonic Acid; Arachidonic Acids; Cells, Cultured; Corticotropin-Releasing Hormone; Indomethacin; Kinetics; Masoprocol; Melitten; Phospholipases A; Phospholipases A2; Pituitary Gland, Anterior; Rats | 1986 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
Thrombin effects on cultured nerve cells: clinical implications and evidence for a novel mechanism of neuronal activation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Calcium; Cell Line; Cyclic GMP; Indomethacin; Masoprocol; Mice; Neurons; Phospholipases A; Receptors, Cell Surface; Receptors, Thrombin; Thrombin; Time Factors | 1986 |
Antagonism of antigen-induced contraction of isolated guinea-pig trachea by 5-lipoxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Catechols; Chlorpheniramine; Guinea Pigs; Hypersensitivity; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrazoles; SRS-A; Trachea | 1986 |
Coordinate actions of arachidonic acid and protein kinase C in gonadotropin-releasing hormone-stimulated secretion of luteinizing hormone.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cells, Cultured; Drug Synergism; Female; Gonadotropin-Releasing Hormone; Luteinizing Hormone; Masoprocol; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Inbred Strains; Retinaldehyde; Tetradecanoylphorbol Acetate | 1986 |
Reticulocyte lipoxygenase, ingensin, and ATP-dependent proteolysis.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adenosine Triphosphate; Animals; Caseins; Catechols; Chromatography, High Pressure Liquid; Cysteine Endopeptidases; Electrophoresis, Polyacrylamide Gel; Endopeptidases; Enzyme Activation; Hemin; Isoelectric Point; Linoleic Acid; Linoleic Acids; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Multienzyme Complexes; Peptide Hydrolases; Phenanthrolines; Proteasome Endopeptidase Complex; Pyrazoles; Rabbits; Reticulocytes; Salicylamides | 1986 |
Platelet aggregating substance from mononuclear leukocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Coagulation Factors; Catechols; Humans; In Vitro Techniques; Masoprocol; Monocytes; Platelet Activating Factor; Platelet Aggregation | 1986 |
Maintenance of tone, role of arachidonate metabolites, and effects of sensitization in guinea pig trachea.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Arachidonic Acid; Arachidonic Acids; Guinea Pigs; In Vitro Techniques; Indomethacin; Male; Masoprocol; Muscle, Smooth; Ovalbumin; Trachea | 1986 |
Differential effects of putative inhibitors on cytosolic and membrane associated platelet lipoxygenase.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adult; Arachidonate Lipoxygenases; Blood Platelets; Cell Membrane; Cytosol; Humans; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Prostaglandin Antagonists; Pyrazoles; Quercetin; Substrate Specificity; Umbelliferones | 1987 |
Endothelial cell proliferation may be mediated via the production of endogenous lipoxygenase metabolites.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Cattle; Cell Division; Cells, Cultured; DNA; Endothelium; Indomethacin; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Prostaglandin-Endoperoxide Synthases | 1987 |
Inhibition of leukotriene-induced contraction of guinea pig trachea by 5-lipoxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Guinea Pigs; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Muscle Contraction; Muscle, Smooth; Pyrazoles; SRS-A; Trachea | 1987 |
Arachidonic acid is involved in the regulation of hCG induced steroidogenesis in rat Leydig cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Chorionic Gonadotropin; In Vitro Techniques; Kinetics; Leydig Cells; Male; Masoprocol; Rats; Testosterone; Tetradecanoylphorbol Acetate; Type C Phospholipases | 1987 |
Injury to rat hearts produced by an exogenous free radical generating system. Study into the role of arachidonic acid and eicosanoids.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Allopurinol; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Arachidonic Acids; Calcium; Cardiomyopathies; Catalase; Eicosanoic Acids; Free Radicals; In Vitro Techniques; Male; Masoprocol; Myocardial Contraction; Myocardium; Oxygen; Purines; Rats; Rats, Inbred Strains; Superoxide Dismutase; Xanthine Oxidase | 1987 |
Specific inhibition of phorbol diester-induced granulocyte-macrophage progenitor cell (GM-CFU) differentiation by lipoxygenase inhibitors.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Ascorbic Acid; Butylated Hydroxyanisole; Cell Differentiation; Colony-Forming Units Assay; Dexamethasone; Granulocytes; Hematopoietic Stem Cells; Ibuprofen; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Tetradecanoylphorbol Acetate | 1987 |
Inhibitors of cytochrome P-450-dependent arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Aspirin; Clotrimazole; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Indomethacin; Ketoconazole; Male; Masoprocol; Microsomes, Liver; NADP; Oxygenases; Rats; Rats, Inbred Strains | 1988 |
Lipoxygenase-induced lipid peroxidation of isolated cardiac microsomes modulates their calcium-transporting function.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Biological Transport; Calcium; Dogs; Guinea Pigs; In Vitro Techniques; Lipid Peroxides; Lipoxygenase; Male; Masoprocol; Microsomes; Myocardium; Rats | 1988 |
Lipoxygenase inhibitors block O2 responses of hamster cheek pouch arterioles.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine; Animals; Arteries; Arterioles; Catechols; Cricetinae; Fatty Acids, Unsaturated; Lipoxygenase Inhibitors; Male; Masoprocol; Mesocricetus; Methacholine Chloride; Methacholine Compounds; Mouth Mucosa; Oxygen; Partial Pressure; Phenylephrine; Pyrazoles; Reference Values | 1988 |
Acetyl glycerylphosphorylcholine aggregates human platelets through two distinct pathways, both dependent on arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Aspirin; Blood Platelets; Catechols; Chromatography, Thin Layer; Cyclooxygenase Inhibitors; Humans; Imidazoles; In Vitro Techniques; Lipoxygenase Inhibitors; Masoprocol; Phospholipases; Platelet Activating Factor; Platelet Aggregation; Prostanoic Acids; Quinacrine; Radioimmunoassay; Receptors, Prostaglandin; Receptors, Thromboxane; Thromboxane A2; Thromboxane-A Synthase | 1985 |
Augmentation of hypoxic pulmonary vasoconstriction in the isolated perfused rat lung by in vitro antagonists of endothelium-dependent relaxation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Biological Factors; Hydroquinones; Hypoxia; Male; Masoprocol; Nitric Oxide; Norepinephrine; Perfusion; Pulmonary Circulation; Rats; Rats, Inbred Strains; Vasoconstriction | 1988 |
The role of endothelium in tolerance to ethanol-induced contraction of the rat aorta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Alcoholic Intoxication; Animals; Aorta; Chromones; Drug Tolerance; Endothelium; Ethanol; Indomethacin; Male; Masoprocol; Methylene Blue; Myocardial Contraction; Nitric Oxide; Rats; Rats, Inbred Strains; Vasodilator Agents | 1987 |
Modulation of vascular smooth muscle sensitivity by preload and eicosanoid synthesis inhibition.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Dose-Response Relationship, Drug; Eicosanoic Acids; Female; Indomethacin; Masoprocol; Meclofenamic Acid; Methacrylates; Muscle, Smooth, Vascular; Phenylephrine; Potassium Chloride; Quinacrine; Rabbits; Serotonin | 1987 |
Rat's vessel wall generates an antiaggregatory substance independent of prostacyclin production.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Aspirin; Catechols; Endothelium; Female; Humans; In Vitro Techniques; Indomethacin; Masoprocol; Platelet Aggregation; Rats | 1985 |
Suppression of cholesteryl ester accumulation in cultured human monocyte-derived macrophages by lipoxygenase inhibitors.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Arachidonate Lipoxygenases; Catechols; Cholesterol Esters; Humans; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Pyrazoles | 1985 |
Arachidonic acid metabolism in isolated pancreatic islets. IV. Negative ion-mass spectrometric quantitation of monooxygenase product synthesis by liver and islets.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; 8,11,14-Eicosatrienoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Catechols; Cytochrome P-450 Enzyme System; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Insulin; Insulin Secretion; Islets of Langerhans; Lipoxygenase; Masoprocol; Metyrapone; Microsomes; Microsomes, Liver; NADP; Oxygenases; Pyrazoles; Rats; SRS-A | 1985 |
Endothelium-dependent vasodilation by melittin: are lipoxygenase products involved?
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Acetylcholine; Animals; Antioxidants; Arachidonic Acid; Arachidonic Acids; Bee Venoms; Catechols; Endothelium; Female; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Melitten; Muscle, Smooth, Vascular; Nitric Oxide; Phospholipases; Pyrazoles; Rabbits; Vasodilation; Vasodilator Agents | 1985 |
Eosinophil adherence to infective larvae of Trichinella spiralis: quantification and modulation.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Antibodies; Antibody Specificity; Catechols; Cell Adhesion; Dose-Response Relationship, Immunologic; Eosinophils; Guinea Pigs; Histamine; Larva; Male; Masoprocol; Mice; Oxygen Consumption; Pyrazoles; Rabbits; Temperature; Trichinellosis | 1985 |
Inhibition of neutrophil phospholipase A2 by p-bromophenylacyl bromide, nordihydroguaiaretic acid, 5,8,11,14-eicosatetraynoic acid and quercetin.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Animals; Catechols; Fatty Acids, Unsaturated; Flavonoids; Masoprocol; Neutrophils; Phospholipases A; Phospholipases A2; Quercetin; Rabbits | 1985 |
Activation of cyclic nucleotide formation in murine neuroblastoma N1E-115 cells by modified human thrombins.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Antioxidants; Catechols; Cell Line; Cyclic GMP; Humans; Indomethacin; Kinetics; Masoprocol; Mice; Neuroblastoma; Quinacrine; Structure-Activity Relationship; Thrombin | 1984 |
Beta-endorphin and adrenocorticotropin release from rat adenohypophysis in vitro: evidence for local modulation by arachidonic acid metabolites of the cyclooxygenase and lipoxygenase pathway.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Adrenocorticotropic Hormone; Animals; Arachidonic Acids; beta-Endorphin; Catechols; Dinoprostone; Endorphins; In Vitro Techniques; Indomethacin; Male; Masoprocol; Pituitary Gland, Anterior; Prostaglandins E; Pyrazoles; Rats; Rats, Inbred Strains | 1984 |
Biosynthesis of lipoxygenase products by enzyme preparations from normal and psoriatic skin.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Catechols; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Psoriasis; Reference Standards; Skin | 1984 |
Bradykinin receptor-mediated cyclic GMP formation in a nerve cell population (murine neuroblastoma clone N1E-115).
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Bradykinin; Calcium; Catechols; Cell Line; Clone Cells; Cyclic GMP; Kinetics; Lipoxygenase Inhibitors; Masoprocol; Mice; Neuroblastoma; Neurons; Phospholipases A; Phospholipases A2; Quinacrine; Receptors, Bradykinin; Receptors, Neurotransmitter | 1984 |
Effect of 15-hydroxyeicosatetraenoic acid (15-HETE) on anti-immunoglobulin E- and calcium ionophore-induced histamine release from human leukocytes. Comparison with the effects of eicosatetraynoic acid and nordihydroguaiaretic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Animals; Antibodies, Anti-Idiotypic; Arachidonic Acids; Calcimycin; Catechols; Dose-Response Relationship, Immunologic; Histamine Release; Humans; Hydroxyeicosatetraenoic Acids; Hypersensitivity, Immediate; Immunoglobulin E; Immunosuppressive Agents; Leukocytes; Masoprocol; Rabbits | 1984 |
Evidence for inhibition of leukotriene A4 synthesis by 5,8,11,14-eicosatetraynoic acid in guinea pig polymorphonuclear leukocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Antioxidants; Arachidonic Acids; Catechols; Chromatography, High Pressure Liquid; Fatty Acids, Unsaturated; Guinea Pigs; Kinetics; Leukotriene A4; Masoprocol; Neutrophils | 1981 |
Acetyl glyceryl ether phosphorylcholine stimulates leukotriene B4 synthesis in human polymorphonuclear leukocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Catechols; Cell Aggregation; Chromatography, Gas; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Masoprocol; Mass Spectrometry; Neutrophils; Platelet Activating Factor | 1982 |
Neutrophil aggregating properties of PAF-acether and leukotriene B4.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Catechols; Cell Aggregation; Dose-Response Relationship, Drug; Indomethacin; Leukotriene B4; Male; Masoprocol; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1983 |
Inhibitors of prostaglandin synthesis block the induction of staphylococcal enterotoxin B-activated T-suppressor cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Catechols; Cells, Cultured; Cyclic AMP; Enterotoxins; Imidazoles; Indomethacin; Lymphocyte Activation; Male; Masoprocol; Mice; Mice, Inbred BALB C; Prostaglandins; Pyrogallol; T-Lymphocytes, Regulatory; Theophylline | 1983 |
A radiochemical assay for detection of leukotriene B4 production from isolated cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Calcimycin; Catechols; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Indomethacin; Kinetics; Leukotriene B4; Male; Masoprocol; Rats; Rats, Inbred Strains; Tritium | 1984 |
Action of luteinizing hormone-releasing hormone: involvement of novel arachidonic acid metabolites.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Catechols; Gonadotropin-Releasing Hormone; Indomethacin; Kinetics; Luteinizing Hormone; Male; Masoprocol; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1983 |
Arachidonic acid metabolism in the murine eosinophil. III. Effect of nonsteroid anti-inflammatory drugs on lymphokine-directed eosinophil migration in vivo.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents; Arachidonic Acids; Aspirin; Catechols; Cell Migration Inhibition; Dose-Response Relationship, Drug; Eosinophils; Indomethacin; Lymphokines; Male; Masoprocol; Mice; Mice, Inbred CBA; Pyrazoles; Rats | 1983 |
Induction of plasminogen activator by 12-O-tetradecanoylphorbol-13-acetate and calcium ionophore. Suppression by inhibitors of fatty acid lipoxygenase.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Bacterial Agents; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Cells, Cultured; Enzyme Induction; Fatty Acids; HeLa Cells; Humans; Hydroxyeicosatetraenoic Acids; Leukemia, Experimental; Lipoxygenase Inhibitors; Masoprocol; Phorbols; Plasminogen Activators; Rats; Tetradecanoylphorbol Acetate | 1983 |
Lipoxygenase activity in human uterine and intrauterine tissues: new prospects for control of prostacyclin production in pre-eclampsia.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acid; Arachidonic Acids; Catechols; Cervix Uteri; Epoprostenol; Female; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase; Masoprocol; Myometrium; Pre-Eclampsia; Pregnancy; Prostaglandins; Uterus | 1983 |
Lipoxygenase inhibitors alter aggregation and adhesiveness of human blood platelets from aspirin-treated patients.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Diphosphate; Arachidonic Acid; Arachidonic Acids; Aspirin; Catechols; Collagen; Humans; Lipoxygenase Inhibitors; Masoprocol; Platelet Adhesiveness; Platelet Aggregation | 1983 |
Endothelium-dependent relaxation of rabbit aorta. I. Relaxation stimulated by arachidonic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Catechols; Dose-Response Relationship, Drug; Drug Synergism; Endothelium; Indomethacin; Male; Masoprocol; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Rabbits | 1983 |
Demonstration of two unique metabolites of arachidonic acid from phorbol ester-stimulated bovine lymphocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cattle; Cyclooxygenase Inhibitors; Enzyme Activation; Kinetics; Lipoxygenase; Lipoxygenase Inhibitors; Lymphocyte Activation; Lymphocytes; Masoprocol; Phorbol Esters; Phorbols; Tetradecanoylphorbol Acetate | 1983 |
Stimulatory effect of lymphocytes from Chagas' patients on spontaneously beating rat atria.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Catechols; Chagas Cardiomyopathy; Chagas Disease; Chromones; Dose-Response Relationship, Immunologic; Humans; In Vitro Techniques; Indomethacin; Leukocyte Count; Lymphocytes; Male; Masoprocol; Myocardial Contraction; Rats; Rats, Inbred Strains; SRS-A; Time Factors | 1984 |
Effects of antioxidants on cyclooxygenase and lipoxygenase activities in intact human platelets: comparison with indomethacin and ETYA.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Antioxidants; Blood Platelets; Catechols; Fatty Acids, Unsaturated; Humans; Indomethacin; Lipoxygenase; Masoprocol; Naphthols; Propyl Gallate; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Quercetin | 1983 |
Inhibition of steroid production in Leydig cells by non-steroidal anti-inflammatory and related compounds: evidence for the involvement of lipoxygenase products in steroidogenesis.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Anti-Inflammatory Agents; Arachidonate Lipoxygenases; Aspirin; Catechols; In Vitro Techniques; Indomethacin; Leydig Cells; Lipoxygenase; Lipoxygenase Inhibitors; Male; Masoprocol; Pregnenolone; Propionates; Pyrazoles; Rats; Testosterone | 1984 |
Differential effects of putative lipoxygenase inhibitors on arachidonic acid metabolism in cell-free and intact cell preparations.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Macrophages; Masoprocol; Mice; Neutrophils; Pyrazoles; Quercetin; Rats | 1984 |
Spasmogenic properties of platelet-activating factor: evidence for a direct mechanism in the contractile response of pulmonary tissues.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aspirin; Blood Platelets; Catechols; Chromones; Dose-Response Relationship, Drug; Guinea Pigs; Indomethacin; Lung; Masoprocol; Muscle Contraction; Muscle, Smooth; Platelet Activating Factor; Rats; Sulfinpyrazone; Thromboxane B2 | 1983 |
A role for endogenous mono-hydroxy-eicosatetraenoic acids (HETEs) in the regulation of human neutrophil migration.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acids; Catechols; Cell Movement; Chemotaxis, Leukocyte; Humans; Lipoxygenase Inhibitors; Masoprocol; Neutrophils; Oxidation-Reduction; Subcellular Fractions | 1980 |
Inhibition of arachidonic acid-induced contraction of guinea pig lung strips.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Chromones; Dose-Response Relationship, Drug; Ethers; Fatty Acids, Unsaturated; Guinea Pigs; Indomethacin; Lung; Male; Masoprocol; Pyrazoles | 1981 |
Stimulation of human neutrophil degranulation with 1-O-octadecyl-2-O-acetyl-SN-glyceryl-3-phosphorylcholine: modulation by inhibitors of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Calcium; Catechols; Cyclooxygenase Inhibitors; Cytochalasin B; Cytoplasmic Granules; Humans; Lipoxygenase Inhibitors; Lysophosphatidylcholines; Masoprocol; Muramidase; Neutrophils; Platelet Activating Factor | 1982 |
Effect of inhibitors of arachidonic acid metabolism on alpha-aminoisobutyric acid transport in human lymphocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Alkynes; Aminoisobutyric Acids; Arachidonic Acid; Arachidonic Acids; Biological Transport, Active; Catechols; Cyclooxygenase Inhibitors; Humans; In Vitro Techniques; Lymphocytes; Masoprocol; Thromboxane-A Synthase | 1982 |
Estrogens induce lipoxygenase derivative formation in rabbit lens.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Catechols; Cyclooxygenase Inhibitors; Enzyme Induction; Estrogens; Ethinyl Estradiol; Hydroxyeicosatetraenoic Acids; Indomethacin; Lens, Crystalline; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Norethindrone; Rabbits | 1982 |
Role of oxidants in TNF-alpha-mediated cytotoxicity.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Cell Survival; Chelating Agents; Curcumin; Free Radical Scavengers; L Cells; Lipoxygenase Inhibitors; Masoprocol; Mice; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 1995 |
Interleukin-1 increases 15-hydroxyeicosatetraenoic acid formation in cultured human endothelial cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonate 15-Lipoxygenase; Arachidonic Acid; Aspirin; Base Sequence; Carbon Radioisotopes; Cells, Cultured; Endothelium; Gene Expression; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Interleukin-1; Masoprocol; Molecular Sequence Data; Monocytes; Polymerase Chain Reaction; Recombinant Proteins; RNA; RNA, Messenger | 1993 |
Role of lipoxygenase metabolites in ischemic preconditioning.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Calcium; Eicosanoids; Hydroxyeicosatetraenoic Acids; Lipoxygenase; Male; Masoprocol; Myocardial Ischemia; Perfusion; Phospholipases A; Rats; Rats, Sprague-Dawley | 1995 |
Mechanism of basal and transforming growth factor beta 1 stimulated H2O2 release by endothelial cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Allopurinol; Animals; Biphenyl Compounds; Cattle; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Indomethacin; Masoprocol; NADH, NADPH Oxidoreductases; NADPH Oxidases; Onium Compounds; Transforming Growth Factor beta; Xanthine Dehydrogenase; Xanthine Oxidase | 1993 |
Possible involvement of arachidonic acid and eicosanoids in metamorphic events in Hydractinia echinata (Coelenterata; Hydrozoa).
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Aspirin; Carbon Radioisotopes; Eicosanoids; Gas Chromatography-Mass Spectrometry; Hydra; Hydroxyeicosatetraenoic Acids; Indomethacin; Lipoxygenase; Masoprocol; Metamorphosis, Biological; Phospholipids | 1994 |
Importance of arachidonic acid metabolites in regulating ATP-induced calcium fluxes in thyroid FRTL-5 cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Cell Line; Econazole; Inositol Phosphates; Masoprocol; Phospholipases A; Phospholipases A2; Rats; Signal Transduction; Thyroid Gland | 1994 |
Lipoxygenase activity in rat embryos and its potential for xenobiotic oxidation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Benzidines; Embryo, Mammalian; Female; Linoleic Acid; Linoleic Acids; Lipoxygenase; Masoprocol; Oxidation-Reduction; Pregnancy; Rats; Rats, Sprague-Dawley; Xenobiotics | 1993 |
Arachidonic acid-induced hormone release in somatotropes: involvement of calcium.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Calcium; Calcium Channels; Cells, Cultured; Cyclooxygenase Inhibitors; Drug Synergism; Enzyme Inhibitors; Female; Growth Hormone; Indomethacin; Leukotrienes; Lipoxygenase Inhibitors; Masoprocol; Pituitary Gland, Anterior; Protein Kinase C; Rats; Rats, Wistar; Spectrometry, Fluorescence | 1996 |
Dual effects of arachidonic acid on ATP-sensitive K+ current of coronary smooth muscle cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenosine Triphosphate; Animals; Arachidonic Acid; Coronary Vessels; Dialysis; Dogs; Dose-Response Relationship, Drug; Electric Conductivity; Indomethacin; Masoprocol; Muscle, Smooth, Vascular; Osmolar Concentration; Patch-Clamp Techniques; Potassium; Solutions | 1996 |
High D-glucose-induced changes in endothelial Ca2+/EDRF signaling are due to generation of superoxide anions.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta; Bradykinin; Calcium; Cells, Cultured; Cyclic GMP; Cytochalasin B; Deferoxamine; Econazole; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Gossypol; Imidazoles; Imidazolidines; Indomethacin; Kinetics; Masoprocol; Miconazole; Nitric Oxide; Nitric Oxide Synthase; Signal Transduction; Superoxides; Swine; Time Factors | 1996 |
Activation of phospholipase D by prostaglandin F2 alpha in rat luteal cells and effects of inhibitors of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Dinoprost; Enzyme Activation; Female; Glycerophospholipids; Indomethacin; Kinetics; Lipoxygenase Inhibitors; Luteal Cells; Masoprocol; Phosphatidic Acids; Phospholipase D; Rats; Rats, Sprague-Dawley; Tritium | 1995 |
Endotoxin stimulates in vitro pituitary growth hormone release in eicosanoid-dependent manner.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acids; Calcium Channel Blockers; Cyclic AMP-Dependent Protein Kinases; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Eicosanoids; Endotoxins; Growth Hormone; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Male; Masoprocol; Protein Kinase C; Sheep; Signal Transduction; Tetradecanoylphorbol Acetate; Verapamil | 1996 |
Partial mediation of glucocorticoid antiproliferative effects by lipocortins.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Annexins; Arachidonic Acid; Dexamethasone; Glucocorticoids; Humans; Hydrocortisone; Lymphocyte Activation; Lymphocytes; Masoprocol; Prednisolone | 1996 |
Conductive Na+ transport in fetal lung alveolar apical membrane vesicles is regulated by fatty acids and G proteins.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Amiloride; Animals; Arachidonic Acid; Biological Transport; Cell Membrane; Enzyme Inhibitors; Fatty Acids; Fetus; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Guinea Pigs; Indomethacin; Masoprocol; Pulmonary Alveoli; Quinacrine; Sodium; Sodium Channels; Thionucleotides | 1997 |
Upregulation of Na(+)-K(+)-2Cl- cotransporter activity in rat parotid acinar cells by muscarinic stimulation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adrenergic alpha-1 Receptor Agonists; Ammonium Chloride; Animals; Arachidonic Acid; Carbachol; Carrier Proteins; Enzyme Inhibitors; Masoprocol; Muscarinic Agonists; Parotid Gland; Phospholipases A; Phospholipases A2; Rats; Sodium-Potassium-Chloride Symporters; Up-Regulation | 1997 |
Mechanisms of hypoxia-induced cerebrovascular dilation in the newborn pig.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Animals, Newborn; Arterioles; Carbon Dioxide; Cerebrovascular Circulation; Hypoxia, Brain; Isoproterenol; Masoprocol; Microcirculation; N-Methylaspartate; Nitroprusside; Oxygen; Partial Pressure; Pia Mater; Swine; Tetrodotoxin; Theophylline; Vasodilation | 1997 |
Tumor cell-endothelial cell interactions: evidence for roles for lipoxygenase products of arachidonic acid in metastasis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Calcimycin; Cattle; Cell Adhesion; Endothelium, Vascular; Humans; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; Neoplasm Metastasis; Neoplasms; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1997 |
Arachidonic acid metabolites and the synaptic potentiation evoked by activation of metabotropic glutamate receptors.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; In Vitro Techniques; Indomethacin; Lipoxygenase Inhibitors; Masoprocol; Rats; Receptors, Metabotropic Glutamate; Synapses | 1998 |
Polyunsaturated fatty acid inhibition of fatty acid synthase transcription is independent of PPAR activation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Cells, Cultured; Corn Oil; Cottonseed Oil; Dietary Fats; Fatty Acid Synthases; Fish Oils; Food, Fortified; Liver; Male; Masoprocol; Mice; Mice, Inbred BALB C; Nuclear Proteins; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Transcription Factors; Transcription, Genetic | 1998 |
Cytokine-mediated growth hormone release from cultured ovine pituitary cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Calcium Channel Blockers; Cells, Cultured; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cytokines; Gonadotropin-Releasing Hormone; Growth Hormone; Interferon-gamma; Interleukin-1; Interleukin-2; Male; Masoprocol; Nifedipine; Orchiectomy; Pituitary Gland, Anterior; Radioimmunoassay; Sheep; Signal Transduction; Somatostatin; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1998 |
Inhibition of the synthesis of eicosanoid-like substances in a human oral cancer cell line by interferon-gamma and eicosapentaenoic acid.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Analysis of Variance; Arachidonic Acids; Carcinoma; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dexamethasone; Eicosanoids; Eicosapentaenoic Acid; Gingival Neoplasms; Glucocorticoids; Hot Temperature; Humans; Indomethacin; Interferon-gamma; Masoprocol; Spectrophotometry, Ultraviolet; Tumor Cells, Cultured | 1998 |
Induction of apoptosis by arachidonic acid in chronic myeloid leukemia cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Animals; Antioxidants; Apoptosis; Arachidonic Acid; Bone Marrow Cells; Caffeic Acids; Cell Division; Colony-Forming Units Assay; Erythroid Precursor Cells; Female; Hematopoietic Stem Cells; Humans; Indomethacin; Ketoconazole; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Male; Masoprocol; Mice; Middle Aged; Tumor Cells, Cultured | 1999 |
Inhibition of GABA(A) receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with alpha1beta2gamma2 GABAR subunits.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anticonvulsants; Arachidonic Acid; Binding, Competitive; Cells, Cultured; Cyclooxygenase Inhibitors; Diazepam; Dose-Response Relationship, Drug; Fatty Acids; Fatty Acids, Monounsaturated; GABA Antagonists; GABA Modulators; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Humans; Indomethacin; Kidney; Linoleic Acid; Masoprocol; Membrane Potentials; Patch-Clamp Techniques; Pentobarbital; Picrotoxin; Receptors, GABA-A; Recombinant Proteins; Transfection; Triazoles | 2000 |
Effects of eicosanoids and nitric oxide on the noradrenaline-induced contractions in the rat mesenteric bed.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Eicosanoids; In Vitro Techniques; Indomethacin; Male; Masoprocol; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Rats; Splanchnic Circulation; Vasoconstriction | 2000 |
N-acylethanolamines are metabolized by lipoxygenase and amidohydrolase in competing pathways during cottonseed imbibition.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Amides; Amidohydrolases; Biological Transport; Cannabinoid Receptor Modulators; Carbon Radioisotopes; Endocannabinoids; Ethanolamines; Fatty Acids; Germination; Gossypium; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Palmitic Acids; Seeds | 2002 |
Lipoxygenase inhibitors enhance tumor suppressive effects of jun proteins on v-myb-transformed monoblasts BM2.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Antioxidants; Apoptosis; Arachidonic Acids; Cell Cycle; Cell Division; Cells, Cultured; Chickens; Genes, myb; Humans; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Monocytes; Proto-Oncogene Proteins c-jun; Umbelliferones | 2003 |