5,8,11,14-eicosatetraynoic acid has been researched along with leukotriene b4 in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (76.92) | 18.7374 |
| 1990's | 6 (23.08) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Falck, JR; Powell, WS; Wainwright, S; Yadagiri, P | 1 |
| Epps, DE; Fitzpatrick, FA; Justen, JM; Sam, LM; Smith, RJ; Wynalda, MA; Yein, FS | 1 |
| Anderson, KM; Harris, J; Ondrey, F; Wygodny, JB | 1 |
| Ahmed, AM; Blachier, F; Lacroix, MC; Léger, C; Ollivier-Bousquet, M | 1 |
| Bhattacherjee, P; Boughton-Smith, NK; Follenfant, RL; Garland, LG; Higgs, GA; Hodson, HF; Islip, PJ; Jackson, WP; Moncada, S; Payne, AN | 1 |
| Anderson, GP; Fennessy, MR | 1 |
| Ashida, Y; Kuriki, H; Maki, Y; Makino, H; Saijo, T; Tamura, S; Terao, S | 1 |
| Howe, RC; Morrison, AR; Russell, JH; Sprecher, H; Taylor, AS | 1 |
| Bradford, PG; Rubin, RP | 1 |
| Catt, KJ; Kiesel, L; Naor, Z; Vanderhoek, JY | 1 |
| Ip, MM; Leung, KH | 1 |
| Niwa, Y; Ohashi, T; Ozaki, Y | 1 |
| Fantini, F | 1 |
| Goetzl, EJ; Kaliner, M; Marom, Z; Shelhamer, JH; Steel, L | 1 |
| Casebolt, TL; Marcelo, CL; Voorhees, JJ; Ziboh, VA | 1 |
| Engstedt, L; Malmsten, CL; Palmblad, J; Rådmark, O; Samuelsson, B; Udén, AM | 1 |
| Borgeat, P; Corey, EJ; Drapeau, J; Fruteau de Laclos, B; Picard, S; Vallerand, P | 1 |
| Gorman, RR; Lin, AH; Morton, DR | 1 |
| Ford-Hutchinson, AW | 1 |
| Kruszewski, J; Płusa, T; Wasek, Z | 1 |
| Aharony, D; Dobson, P; Krell, RD | 1 |
| Dewald, B; Fey, MF; Meier, RW; Niklaus, G; Tobler, A | 1 |
| Nixon, AB; O'Flaherty, JT; Wijkander, J; Wykle, RL | 1 |
| Coffey, RG; Diaz, S; Specter, S; Vanderhoek, JY | 1 |
| Breton, J; Chabot-Fletcher, M; DeWolf, W; Griswold, D; Hillegass, L; Keller, P | 1 |
| Hammarström, S; Herbertsson, H; Kühme, T | 1 |
2 review(s) available for 5,8,11,14-eicosatetraynoic acid and leukotriene b4
| Article | Year |
|---|---|
The effects of a novel series of selective inhibitors of arachidonate 5-lipoxygenase on anaphylactic and inflammatory responses.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anaphylaxis; Animals; Arachidonate 5-Lipoxygenase; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Bronchial Provocation Tests; Bronchial Spasm; Fever; Gastric Mucosa; Guinea Pigs; Humans; Hydroxamic Acids; Inflammation; Leukocytes; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; Rats; SRS-A | 1988 |
[Role of arachidonic acid (ETE) and its metabolites in the pathogenesis of bronchial spasm. II. Metabolites formed under the effect of lipoxygenase].
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anaphylaxis; Asthma; Bronchi; Bronchial Spasm; Fatty Acids, Unsaturated; Humans; Leukotriene B4; Lipoxygenase; Muscle, Smooth; SRS-A | 1983 |
24 other study(ies) available for 5,8,11,14-eicosatetraynoic acid and leukotriene b4
| Article | Year |
|---|---|
Metabolism of 12(S)-hydroxy-5,8,10,14-eicosatetraenoic acid and other hydroxylated fatty acids by the reductase pathway in porcine polymorphonuclear leukocytes.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Aldehyde Oxidoreductases; Animals; Fatty Acids; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Linoleic Acids; Molecular Conformation; Neutrophils; Oxidation-Reduction; Substrate Specificity; Swine | 1990 |
Human neutrophil activation with interleukin-1. A role for intracellular calcium and arachidonic acid lipoxygenation.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Aminoquinolines; Arachidonic Acid; Arachidonic Acids; Calcium; Chlortetracycline; Cytochalasin B; Dose-Response Relationship, Drug; Fluorescent Dyes; Gallic Acid; Humans; Interleukin-1; Leukotriene B4; Lipoxygenase; Neutrophils; Sulfonamides; Tosylphenylalanyl Chloromethyl Ketone | 1987 |
Human PC-3 prostate cell line DNA synthesis is suppressed by eicosatetraynoic acid, an in vitro inhibitor of arachidonic acid metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adenocarcinoma; Arachidonic Acid; Arachidonic Acids; Calcimycin; Cyclooxygenase Inhibitors; DNA; Fatty Acids, Unsaturated; Humans; Indomethacin; Leukotriene B4; Lipoxygenase Inhibitors; Male; Phospholipids; Prostatic Neoplasms; Tumor Cells, Cultured | 1988 |
Arachidonic acid metabolism and casein secretion in lactating rabbit mammary epithelial cells: effects of inhibitors of prostaglandins and leukotrienes synthesis.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Caffeic Acids; Caseins; Cyclooxygenase Inhibitors; Dinoprost; Docosahexaenoic Acids; Epithelium; Female; Glutathione Transferase; Indomethacin; Lactation; Leukotriene B4; Lipoxygenase Inhibitors; Mammary Glands, Animal; Masoprocol; Pregnancy; Prolactin; Prostaglandins F; Rabbits; SRS-A | 1988 |
Lipoxygenase metabolites mediate increased airways responsiveness to histamine after acute platelet activating factor exposure in the guinea-pig.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Airway Resistance; Animals; Aspirin; Bronchi; Chromones; Female; Guinea Pigs; Histamine; Leukotriene B4; Lipoxygenase; Lung Compliance; Male; Platelet Activating Factor; Pyrazoles; Quinolinium Compounds; SRS-A | 1988 |
The antiallergic agent amoxanox suppresses SRS-A generation by inhibiting lipoxygenase.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Aminopyridines; Animals; Asthma; Calcimycin; Cattle; Guinea Pigs; Histamine H1 Antagonists; Hydroxyeicosatetraenoic Acids; Hypersensitivity; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Lung; Male; Monocytes; Prostaglandins; Rats; Rats, Inbred Strains; SRS-A; Thromboxane B2 | 1986 |
Inhibition of cytotoxic T lymphocyte-mediated lysis by ETYA: effect independent of arachidonic acid metabolism.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Binding, Competitive; Clone Cells; Cytotoxicity, Immunologic; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase Inhibitors; Lymphocyte Culture Test, Mixed; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Inbred DBA; T-Lymphocytes, Cytotoxic | 1985 |
Characterization of formylmethionyl-leucyl-phenylalanine stimulation of inositol trisphosphate accumulation in rabbit neutrophils.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Cytochalasin B; Ethers; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Ionomycin; Kinetics; Leukotriene B4; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Rabbits; Structure-Activity Relationship; Sugar Phosphates | 1985 |
Mechanism of action of gonadotropin releasing hormone: role of lipoxygenase products of arachidonic acid in luteinizing hormone release.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Calcimycin; Catechols; Cells, Cultured; Gonadotropin-Releasing Hormone; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Luteinizing Hormone; Masoprocol; Pituitary Gland; Pyrazoles; Rats; SRS-A | 1985 |
Regulation of rat natural killing. II. Inhibition of cytolysis and activation by inhibitors of lipoxygenase: possible role of leukotrienes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonate Lipoxygenases; Cytotoxicity, Immunologic; Female; Killer Cells, Natural; Leukotriene B4; Lymphocyte Activation; Masoprocol; Phenanthrolines; Quercetin; Rats; Rats, Inbred WF; Spleen; SRS-A | 1986 |
A comparative study on the effects of inhibitors of the lipoxygenase pathway on neutrophil function. Inhibitory effects on neutrophil function may not be attributed to inhibition of the lipoxygenase pathway.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Benzoquinones; Calcimycin; Chemotaxis, Leukocyte; Epoprostenol; Humans; Hydroxides; Hydroxyl Radical; Leukotriene B4; Lipoxygenase Inhibitors; Masoprocol; N-Formylmethionine Leucyl-Phenylalanine; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Phospholipases A; Phospholipases A2; Platelet Activating Factor; Quinones; Tetradecanoylphorbol Acetate; Umbelliferones | 1986 |
[Recent discoveries in the field of mediators of anti-inflammation: leukotrienes].
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arachidonic Acids; Aspirin; Humans; Indomethacin; Inflammation; Leukotriene B4; Muscle, Smooth; Oxidation-Reduction; SRS-A | 1984 |
Prostaglandin-generating factor of anaphylaxis induces mucous glycoprotein release and the formation of lipoxygenase products of arachidonate from human airways.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Glycoproteins; Humans; Hydroxyeicosatetraenoic Acids; In Vitro Techniques; Leukotriene B4; Lipoxygenase; Lung; Mast Cells; Mucus; Oligopeptides | 1984 |
Biosynthesis of lipoxygenase products by enzyme preparations from normal and psoriatic skin.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Arachidonate Lipoxygenases; Arachidonic Acid; Arachidonic Acids; Catechols; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Humans; Hydroxyeicosatetraenoic Acids; Leukotriene B4; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Psoriasis; Reference Standards; Skin | 1984 |
Leukotriene B4 is a potent and stereospecific stimulator of neutrophil chemotaxis and adherence.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Arachidonic Acids; Cell Adhesion; Chemotaxis, Leukocyte; Humans; Hydroxyeicosatetraenoic Acids; Indomethacin; Isomerism; Leukotriene B4; Luminescent Measurements; Neutrophils; SRS-A | 1981 |
Studies on the mechanism of formation of the 5S, 12S-dihydroxy-6,8,10,14(E,Z,E,Z)-icosatetraenoic acid in leukocytes.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Calcimycin; Chromatography, High Pressure Liquid; Gas Chromatography-Mass Spectrometry; Hydroxyeicosatetraenoic Acids; Leukocytes; Leukotriene B4; Swine | 1982 |
Acetyl glyceryl ether phosphorylcholine stimulates leukotriene B4 synthesis in human polymorphonuclear leukocytes.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Catechols; Cell Aggregation; Chromatography, Gas; Dose-Response Relationship, Drug; Humans; Leukotriene B4; Masoprocol; Mass Spectrometry; Neutrophils; Platelet Activating Factor | 1982 |
Neutrophil aggregating properties of PAF-acether and leukotriene B4.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Catechols; Cell Aggregation; Dose-Response Relationship, Drug; Indomethacin; Leukotriene B4; Male; Masoprocol; Neutrophils; Platelet Activating Factor; Platelet Aggregation; Rabbits; Rats; Rats, Inbred Strains; Stimulation, Chemical | 1983 |
A radiochemical assay for detection of leukotriene B4 production from isolated cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Arachidonic Acid; Arachidonic Acids; Ascitic Fluid; Calcimycin; Catechols; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Drug Interactions; Indomethacin; Kinetics; Leukotriene B4; Male; Masoprocol; Rats; Rats, Inbred Strains; Tritium | 1984 |
Inhibition of the arachidonic acid pathway prevents induction of IL-8 mRNA by phorbol ester and changes the release of IL-8 from HL 60 cells: differential inhibition of induced expression of IL-8, TNF-alpha, IL-1 alpha, and IL-1 beta.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Acetophenones; Alkaloids; Arachidonic Acid; Cycloheximide; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Gene Expression; HL-60 Cells; Humans; In Vitro Techniques; Inflammation Mediators; Interleukin-1; Interleukin-8; Leukotriene B4; Lipoxygenase Inhibitors; Phospholipases A; Protein Kinase C; Protein Synthesis Inhibitors; RNA, Messenger; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha | 1995 |
5-Lipoxygenase products modulate the activity of the 85-kDa phospholipase A2 in human neutrophils.
Topics: 5,8,11,14-Eicosatetraynoic Acid; alpha-Linolenic Acid; Arachidonate 5-Lipoxygenase; Arachidonic Acid; Arachidonic Acids; Cytosol; Enzyme Activation; Exocytosis; Humans; Hydroxyeicosatetraenoic Acids; Kinetics; Leukotriene B4; Molecular Weight; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phospholipases A; Phospholipases A2; Tetrazoles | 1995 |
The effect of delta-9-tetrahydrocannabinol on arachidonic acid metabolism in human peripheral blood mononuclear cells.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Adult; Arachidonic Acid; Chromatography, High Pressure Liquid; Dronabinol; Humans; Leukocytes, Mononuclear; Leukotriene B4; Lipoxygenase | 1994 |
Use of a continuous assay of oxygen consumption to evaluate the pharmacology of 5-lipoxygenase inhibitors.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Drug Evaluation, Preclinical; Humans; Hydroxyurea; Imidazoles; In Vitro Techniques; Leukotriene B4; Lipoxygenase Inhibitors; Monocytes; Oxygen Consumption; Rats; Tumor Cells, Cultured | 1993 |
The 650-kDa 12(S)-hydroxyeicosatetraenoic acid binding complex: occurrence in human platelets, identification of hsp90 as a constituent, and binding properties of its 50-kDa subunit.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Adenosine Triphosphate; Binding, Competitive; Blood Platelets; Cells, Cultured; Chromatography, Gel; Cytosol; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Humans; Inhibitory Concentration 50; Leukotriene B4; Ligands; Molecular Weight; Platelet Glycoprotein GPIIb-IIIa Complex; Precipitin Tests; Prostaglandin D2; Protein Binding; Tumor Cells, Cultured | 1999 |