5,7-dichlorokynurenic acid has been researched along with licostinel in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iversen, LL; Leeson, PD | 1 |
| Baker, R; Carling, RW; Foster, AC; Grimwood, S; Hargreaves, R; Hurley, C; Kemp, JA; Kulagowski, JJ; Leeson, PD; Marshall, GR; Rathbone, D; Rowley, M; Saywell, KL; Stevenson, GI; Tricklebank, MD; Watt, AP | 1 |
| Guastella, J; Huettner, JE; Keana, JF; Weber, E; Woodward, RM | 1 |
| Erdõ, SL; Molnár, P | 1 |
| Cai, SX; Espitia, SA; Hawkinson, JE; Keana, JF; Kher, SM; Tran, M; Weber, E; Whittemore, ER; Woodward, RM; Zhou, ZL | 1 |
1 review(s) available for 5,7-dichlorokynurenic acid and licostinel
| Article | Year |
|---|---|
The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Binding Sites; Cognition; Glycine; Humans; Kynurenic Acid; Neuroprotective Agents; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1994 |
4 other study(ies) available for 5,7-dichlorokynurenic acid and licostinel
| Article | Year |
|---|---|
Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists.
Topics: Animals; Blood Proteins; Blood-Brain Barrier; Brain; Excitatory Amino Acid Antagonists; Male; Mice; Protein Binding; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1997 |
In vitro pharmacology of ACEA-1021 and ACEA-1031: systemically active quinoxalinediones with high affinity and selectivity for N-methyl-D-aspartate receptor glycine sites.
Topics: Animals; Binding Sites; Brain; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Electrophysiology; Female; Glycine; Kynurenic Acid; Neurons; Oocytes; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Complementary; RNA, Messenger; Transcription, Genetic; Xenopus laevis | 1995 |
Differential effects of five glycine site antagonists on NMDA receptor desensitisation.
Topics: Animals; Benzothiadiazines; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 1996 |
Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists.
Topics: Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Glycine; Inhibitory Concentration 50; Kynurenic Acid; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 2003 |