5,7-dichlorokynurenic acid and kynurenic acid

5,7-dichlorokynurenic acid has been researched along with kynurenic acid in 117 studies

Research

Studies (117)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	78 (66.67)	18.2507
2000's	30 (25.64)	29.6817
2010's	9 (7.69)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Calligaro, DO; Lodge, D; McQuaid, LA; O'Malley, PJ; Pralong, E; Smith, EC; Wikel, JH	1
Baron, BM; Harrison, BL; Kehne, JH; McDonald, IA; Nyce, PL; Salituro, FG; Stewart, KT; White, HS	1
Baker, R; Carling, RW; Foster, AC; Grimwood, S; Kemp, JA; Leeson, PD; Marshall, GR; Moseley, AM	1
Baker, R; Carling, RW; Curtis, NR; Donald, AE; Foster, AC; Kemp, JA; Leeson, PD; Marshall, GR; Moore, KW; Williams, BJ	1
Baron, BM; Harrison, BL; McDonald, IA; Nyce, PL; Salituro, FG; Stewart, KT	1
Baron, BM; Cousino, DM; Harrison, BL; McDonald, IA	1
Bucsh, RA; Caprathe, BW; Davis, RE; Dickerson, MR; Fergus, J; Jaen, JC; Laborde, E; Marks, J; Sorenson, RJ; Spiegel, K	1
Iversen, LL; Leeson, PD	1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J	1
Blanchard, JC; Canton, T; Doble, A; Jimonet, P; Miquet, JM	1
Lodge, D; Millar, JD; Pralong, E	1
Baron, BM; Chi, EM; Harrison, BL; Kehne, JH; McCloskey, TC; Palfreyman, MG; Whitten, JP	1
Baron, BM; Harrison, BL; Hurt, SD; Palfreyman, MG; Siegel, BW; Slone, AL	1
Baron, BM; Hurt, SD	1
Calligaro, DO; Dingledine, R; McNamara, D; McQuaid, LA; O'Malley, PJ; Smith, EC	1
Baron, BM; Harrison, BL; McDonald, IA; Miller, FP; Palfreyman, MG; Salituro, FG; Schmidt, CJ; Sorensen, SM; White, HS	1
Anegawa, NJ; Lynch, DR; Pritchett, DB; Verdoorn, T	1
Laurie, DJ; Seeburg, PH	1
Aguglia, U; Bertorelli, R; De Sarro, A; De Sarro, G; Ongini, E	2
Hoffman, PL; Iorio, KR; Snell, LD; Tabakoff, B	1
Guastella, J; Huettner, JE; Keana, JF; Weber, E; Woodward, RM	1
Aulakh, CS; Mazzola-Pomietto, P; Murphy, DL	2
Donevan, SD; Fielding, RP; Penix, L; Rho, JM; Rogawski, MA; Subramaniam, S	1
Lukasiewicz, PD; Roeder, RC	1
Nowak, G; Ordway, GA; Paul, IA	1
Ary, T; Faull, RL; McCabe, RT; Narang, N; Sofia, RD; Wamsley, JK	2
McNamara, M; Nowak, G; Paul, IA; Redmond, A	1
Jessa, M; Nazar, M; Palejko, W; Plaznik, A	1
Layer, RT; Nowak, G; Paul, IA; Skolnick, P	1
Chazot, PL; Cik, M; Stephenson, FA	1
Bousquet, P; Feldman, J; Mettauer, B; Monassier, L; Roegel, JC; Tibiriça, E	1
Han, D; Ogita, K; Yoneda, Y	1
Ary, T; Faull, RL; Gan, XD; McCabe, RT; Narang, N; Sofia, RD; Wamsley, JK	1
Layer, RT; Nowak, G; Paul, IA; Skolnick, P; Trullas, R	1
Corbett, R; Dunn, RW	1
Layer, RT; Nowak, G; Paul, IA; Popik, P; Skolnick, P	1
Challiss, RA; Nahorski, SR; Simpson, PB	1
Nowak, G; Paul, IA; Popik, P; Skolnick, P; Young, A	1
Ogita, K; Suzuki, T; Yoneda, Y	1
Kucharczyk, N; McCabe, RT; Sofia, RD; Vogel, JR; Wasterlain, CG	1
Cappendijk, SL; de Vries, R; Dzoljic, MR	1
Han, D; Ogita, K; Suzuki, T; Yoneda, Y	1
Hlinák, Z; Krejci, I	1
Layer, RT; Olds, T; Popik, P; Skolnick, P	1
Domenici, MR; Marinelli, S; Sagratella, S	1
London, ED; Matsunaga, T; Mukhin, AG	1
Blanchard, JC; Boireau, A; Bordier, F; Burgevin, MC; Chevet, T; Daniel, M; Doble, A; Durand, G; Jimonet, P; Malgouris, C; Meunier, M; Mignani, S; Miquet, JM; Pény, C	1
Cai, SX; Egbuwoku, ZO; Hawkinson, JE; Huang, JC; Keana, JF; Lü, Y; Weber, E; Whittemore, ER; Woodward, RM; Zhou, ZL	1
Gunasekar, PG; Kanthasamy, AG; Matsumoto, RR; Trunong, DD	1
Franklin, PH; Ishmael, JE; Leid, M; Murray, TF	1
Baron, BM; Gross, RS; Harrison, BL; Hawes, C; Siegel, BW; Towers, P	1
Blank, T; Köpke, AK; Spiess, J; Sydow, S	1
Erdõ, SL; Molnár, P	1
Gondo, M; Goodman, JC; Robertson, CS; Simpson, RK	1
Aizenman, E; Boeckman, FA	1
Cai, SX; Espitia, SA; Hawkinson, JE; Ilyin, V; Keana, JF; Kher, SM; Tran, M; Weber, E; Woodward, RM; Zhou, ZL	1
Han, Y; Slaughter, MM; Zhang, J	1
Biggio, G; Cuccu, R; Ghiani, CA; Murgia, A; Pisu, MG; Serra, M	1
Matoba, M; Nishikawa, T; Tomita, U	1
Niu, YP; Wigstrom, H; Xiao, MY	1
Leslie, SW; Randall, PK; Robichon, R	1
Furuya, Y; Ogura, H	1
Leibrock, J; Prücher, H; Rautenberg, W	1
Fontana, G; Raiteri, M; Valenti, L	1
Camarasa, J; Camins, A; Escubedo, E; Gabriel, C; Pallàs, M; Sureda, FX	1
Daggett, LP; Deal, C; Hess, SD; Johnson, EC; Lu, CC; Veliçelebi, G	1
Han, Y; Slaughter, MM	1
Maruoka, Y; Nakamura, M; Ohno, Y; Otani, K; Tamamura, C; Tanaka, H; Yasuda, H	1
Faull, RL; Layer, RT; Leiner, KA; McCabe, RT; Narang, N; Sofia, RD; Wamsley, JK	1
Abutidze, K; Barnard, EA; Grishin, EV; Mellor, I; Soloviev, MM; Streit, P; Usherwood, PN	1
Becker, J; Li, Z; Noe, CR	1
Reynolds, IJ; Sharma, TA	1
Konieczny, J; Lorenc-Koci, E; Ossowska, K; Wolfarth, S	1
Hinoi, E; Ogita, K; St'astny, F; Yoneda, Y	1
Mazarati, AM; Wasterlain, CG	1
VanDongen, AM; VanDongen, HM; Wood, MW	1
Harkin, A; Nowak, G; Paul, IA	1
Frankiewicz, T; Parsons, CG; Pilc, A	1
Li, Y; Nowak, G; Paul, IA	1
Nowak, G; Popik, P; Wróbel, M	1
Dannhardt, G; Kohl, BK; Parsons, CG; von Gruchalla, M	1
Harkin, A; Kelly, JP; Leonard, BE; Nally, R	1
Senra-Vidal, A; Sierra-Marcuño, G; Sierra-Paredes, G	1
Kotlińska, J	1
Audus, KL; Hirano, K; Hirose, F; Kupczyk-Subotkowska, L; Ryu, T; Sakaeda, T; Siahaan, TJ; Stella, VJ; Sugawara, T; Tada, Y; Yoshikawa, T	1
Mirshahi, T; Ronald, KM; Woodward, JJ	1
Begon, S; Dubray, C; Eschalier, A; Mazur, A; Pickering, G; Rayssiguier, Y	1
Blantz, RC; Deng, A; Munger, KA; Thomson, SC; Valdivielso, JM	1
Ito, A; Nagata, R; Nakamura, M; Ohtani, K; Tanaka, H; Yasuda, H; Yoneda, Y	1
Boros, A; Dezso, P; Kolok, S; Nagy, J; Szombathelyi, Z	1
Cai, SX; Espitia, SA; Hawkinson, JE; Keana, JF; Kher, SM; Tran, M; Weber, E; Whittemore, ER; Woodward, RM; Zhou, ZL	1
Geiger, JD; Hochman, S; Moore, A; Nath, A; Song, L	1
Furukawa, H; Gouaux, E	1
Albarello, L; Capella, C; Chiaravalli, AM; Dominioni, L; Frigo, G; Giaroni, C; Lecchini, S; Zanetti, E	1
Han, Y; Li, P; Slaughter, MM	1
Johnson, MS; Moretti, L; Pentikäinen, OT; Settimo, L	1
Grundke-Iqbal, I; Haque, N; Iqbal, K; Li, L; Sengupta, A	1
Concas, A; Marino, G; Minei, R; Pierobon, P; Porcu, P; Sogliano, C; Tino, A; Tortiglione, C	1
Barger, SW; Jiang, S; Sims, TJ; Wu, SZ	1
Qiao, H; Wen, L; Yang, S; Zhang, Y; Zhou, W	1
Chizh, BA; Christoph, T; Englberger, W; Reissmüller, E; Schiene, K	1
Akaike, A; Hama, Y; Katsuki, H; Kume, T; Suminaka, C; Tochikawa, Y	1
Chen, PE; Erreger, K; Geballe, MT; Katz, E; Le, P; Lee, CJ; Livesey, MR; O'Toole, KK; Snyder, JP; Traynelis, SF; Wyllie, DJ	1
Cousins, SL; Kenny, AV; Pinho, L; Stephenson, FA	1
Kussius, CL; Popescu, GK	1
Ahn, DK; Bae, YC; Bonfa, E; Park, MK; Woo, YW; Yang, GY	1
Borroni, P; Crema, F; Frigo, G; Giaroni, C; Giuliani, D; Lecchini, S; Marchet, S; Moro, E; Oldrini, R; Trinchera, M; Zanetti, E	1
Ahn, DK; Bae, YC; Kim, MJ; Lee, JH; Park, MK; Park, YY; Won, KA; Yang, GY	1
Borker, P; Prodromou, ML; Salussolia, CL; Wollmuth, LP	1
Camp, M; Debrouse, L; Grant, SG; Gunduz-Cinar, O; Holmes, A; Hurd, B; Kiselycznyk, C; Mishina, M; Plitt, A; Todaro, A	1
Bihel, F; Bourguignon, JJ; Klein, C; Maitre, M; Mensah-Nyagan, AG; Patte-Mensah, C; Schmitt, M; Taleb, O	1
Milanese, M; Oliveri, M; Raiteri, L; Romei, C; Usai, C	1
Inoue, M; Kodama, S; Miyakawa, H; Oda, Y; Tsuchiya, S	1
Acton, D; Miles, GB	1

Reviews

1 review(s) available for 5,7-dichlorokynurenic acid and kynurenic acid

Article	Year
The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential. Journal of medicinal chemistry, 1994, Nov-25, Volume: 37, Issue:24 Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Binding Sites; Cognition; Glycine; Humans; Kynurenic Acid; Neuroprotective Agents; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1994

Other Studies

116 other study(ies) available for 5,7-dichlorokynurenic acid and kynurenic acid

Article	Year
3-Phenyl-4-hydroxyquinolin-2(1H)-ones: potent and selective antagonists at the strychnine-insensitive glycine site on the N-methyl-D-aspartate receptor complex. Journal of medicinal chemistry, 1992, Sep-04, Volume: 35, Issue:18 Topics: Animals; Binding Sites; Glycine; Quinolones; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Strychnine	1992
3-(2-Carboxyindol-3-yl)propionic acid-based antagonists of the N-methyl-D-aspartic acid receptor associated glycine binding site. Journal of medicinal chemistry, 1992, May-15, Volume: 35, Issue:10 Topics: Animals; Binding Sites; Cerebral Cortex; Glycine; Hippocampus; Indoles; Mice; Mice, Inbred DBA; Propionates; Rats; Receptors, N-Methyl-D-Aspartate; Seizures; Structure-Activity Relationship; Strychnine; Substrate Specificity	1992
2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the NMDA receptor. Journal of medicinal chemistry, 1992, May-29, Volume: 35, Issue:11 Topics: Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Glycine; Hippocampus; Kynurenic Acid; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Quinolines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; X-Ray Diffraction	1992
Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor. Journal of medicinal chemistry, 1991, Volume: 34, Issue:4 Topics: Animals; Binding, Competitive; Glycine; Indicators and Reagents; Kynurenic Acid; Molecular Structure; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1991
3-(2-carboxyindol-3-yl)propionic acid derivatives: antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex. Journal of medicinal chemistry, 1990, Volume: 33, Issue:11 Topics: Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Glycine; Hippocampus; Indoles; Molecular Structure; N-Methylaspartate; Propionates; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Strychnine	1990
4-[(Carboxymethyl)oxy]- and 4-[(carboxymethyl)amino]-5,7-dichloroquinoline-2-carboxylic acid: new antagonists of the strychnine-insensitive glycine binding site on the N-methyl-D-aspartate receptor complex. Journal of medicinal chemistry, 1990, Volume: 33, Issue:12 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Glycine; Kynurenic Acid; Molecular Structure; Quinolines; Rats; Receptors, N-Methyl-D-Aspartate; Strychnine	1990
Kynurenic acid derivatives inhibit the binding of nerve growth factor (NGF) to the low-affinity p75 NGF receptor. Journal of medicinal chemistry, 1995, Oct-27, Volume: 38, Issue:22 Topics: Animals; CHO Cells; Cricetinae; Guinea Pigs; Humans; Kynurenic Acid; Membrane Glycoproteins; Molecular Structure; Nerve Growth Factors; PC12 Cells; Pyridones; Quinazolines; Rats; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Recombinant Proteins	1995
Chemical genetics reveals a complex functional ground state of neural stem cells. Nature chemical biology, 2007, Volume: 3, Issue:5 Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells	2007
A rapid filtration assay for the glycine binding site on the NMDA receptor in rat cortical membranes using [3H]dichlorokynurenic acid. The Journal of pharmacy and pharmacology, 1992, Volume: 44, Issue:10 Topics: Animals; Binding Sites; Cerebral Cortex; Filtration; Glycine; In Vitro Techniques; Kynurenic Acid; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tritium	1992
Specificity and potency of N-methyl-D-aspartate glycine site antagonists and of mephenesin on the rat spinal cord in vitro. Neuroscience letters, 1992, Feb-17, Volume: 136, Issue:1 Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glycine; Ibotenic Acid; Indoles; Kynurenic Acid; Mephenesin; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord	1992
NMDA receptor complex antagonists have potential anxiolytic effects as measured with separation-induced ultrasonic vocalizations. European journal of pharmacology, 1991, Feb-14, Volume: 193, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Anti-Anxiety Agents; Anxiety, Separation; Behavior, Animal; Buspirone; Diazepam; Dioxins; Dizocilpine Maleate; Dose-Response Relationship, Drug; Indoles; Kynurenic Acid; Maternal Deprivation; Mephenesin; Piperidines; Quinolizines; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Receptors, Serotonin; Serotonin Antagonists; Spiro Compounds; Valine; Vocalization, Animal	1991
[3H]5,7-dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sites. European journal of pharmacology, 1991, Feb-25, Volume: 206, Issue:2 Topics: Allosteric Regulation; Animals; Binding Sites; Brain; Glycine; In Vitro Techniques; Kynurenic Acid; Ligands; Male; Polyamines; Radioligand Assay; Rats; Rats, Inbred Strains; Receptors, N-Methyl-D-Aspartate; Strychnine; Synaptosomes	1991
[3H] 5,7-dichlorokynurenic acid, a high affinity ligand for the NMDA receptor glycine regulatory site. Journal of receptor research, 1991, Volume: 11, Issue:1-4 Topics: Animals; Glycine; Kynurenic Acid; Ligands; Molecular Structure; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Tritium	1991
5,7-Dichlorokynurenic acid, a potent and selective competitive antagonist of the glycine site on NMDA receptors. Neuroscience letters, 1990, Nov-27, Volume: 120, Issue:1 Topics: Animals; Binding, Competitive; Brain; Evoked Potentials; Female; Glycine; Kinetics; Kynurenic Acid; N-Methylaspartate; Oocytes; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Structure-Activity Relationship; Xenopus	1990
Activity of 5,7-dichlorokynurenic acid, a potent antagonist at the N-methyl-D-aspartate receptor-associated glycine binding site. Molecular pharmacology, 1990, Volume: 38, Issue:4 Topics: Animals; Calcium; gamma-Aminobutyric Acid; Glycine; In Vitro Techniques; Kynurenic Acid; Male; N-Methylaspartate; Norepinephrine; Phencyclidine; Rats; Rats, Inbred Strains; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter	1990
N-methyl-D-aspartate receptors: different subunit requirements for binding of glutamate antagonists, glycine antagonists, and channel-blocking agents. Molecular pharmacology, 1994, Volume: 45, Issue:3 Topics: Binding Sites; Cells, Cultured; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Glycine; Humans; Ion Channels; Kynurenic Acid; Receptors, N-Methyl-D-Aspartate; Transfection	1994
Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition. European journal of pharmacology, 1994, Aug-16, Volume: 268, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Autoradiography; Binding Sites; Binding, Competitive; Brain; Cloning, Molecular; Dizocilpine Maleate; DNA; Glutamic Acid; Ion Channels; Kinetics; Kynurenic Acid; Ligands; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins	1994
Excitatory amino acid neurotransmission through both NMDA and non-NMDA receptors is involved in the anticonvulsant activity of felbamate in DBA/2 mice. European journal of pharmacology, 1994, Sep-01, Volume: 262, Issue:1-2 Topics: Acoustic Stimulation; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Anticonvulsants; Binding, Competitive; Disease Models, Animal; Dose-Response Relationship, Drug; Felbamate; Female; Glycine; Injections, Intraperitoneal; Injections, Intraventricular; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; N-Methylaspartate; Phenylcarbamates; Propylene Glycols; Quinoxalines; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Seizures; Serine; Stereoisomerism; Synaptic Transmission	1994
Attenuation of glutamate-induced neurotoxicity in chronically ethanol-exposed cerebellar granule cells by NMDA receptor antagonists and ganglioside GM1. Alcoholism, clinical and experimental research, 1995, Volume: 19, Issue:3 Topics: Alcohol Withdrawal Delirium; Alcoholism; Animals; Animals, Newborn; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Female; G(M1) Ganglioside; Glutamic Acid; Kynurenic Acid; Neurons; Pipecolic Acids; Rats; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Up-Regulation	1995
In vitro pharmacology of ACEA-1021 and ACEA-1031: systemically active quinoxalinediones with high affinity and selectivity for N-methyl-D-aspartate receptor glycine sites. Molecular pharmacology, 1995, Volume: 47, Issue:3 Topics: Animals; Binding Sites; Brain; Cells, Cultured; Cloning, Molecular; DNA, Complementary; Electrophysiology; Female; Glycine; Kynurenic Acid; Neurons; Oocytes; Quinoxalines; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; RNA, Complementary; RNA, Messenger; Transcription, Genetic; Xenopus laevis	1995
The NMDA receptor complex modulates clonidine-induced increases in growth hormone levels in rats. Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:2 Topics: Animals; Clonidine; Growth Hormone; Kynurenic Acid; Male; Quinoxalines; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	1995
Felbamate block of the N-methyl-D-aspartate receptor. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:2 Topics: Animals; Anticonvulsants; Cells, Cultured; Dizocilpine Maleate; Felbamate; Kynurenic Acid; Membrane Potentials; Phenylcarbamates; Propylene Glycols; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Tritium	1995
Evidence for glycine modulation of excitatory synaptic inputs to retinal ganglion cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:6 Topics: Ambystoma; Animals; Biological Transport; Dendrites; Dose-Response Relationship, Drug; Evoked Potentials; Glycine; In Vitro Techniques; Kinetics; Kynurenic Acid; Light; Patch-Clamp Techniques; Potassium Chloride; Receptors, N-Methyl-D-Aspartate; Retinal Ganglion Cells; Serine; Stereoisomerism; Synapses; Synaptic Transmission; Time Factors	1995
Alterations in the N-methyl-D-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims. Brain research, 1995, Mar-27, Volume: 675, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Adult; Dizocilpine Maleate; Female; Frontal Lobe; Humans; In Vitro Techniques; Kynurenic Acid; Male; Middle Aged; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Suicide	1995
Use of [3H]5,7 dichlorokynurenic acid to identify strychnine-insensitive glycine receptors in human postmortem brain. Brain research bulletin, 1994, Volume: 35, Issue:3 Topics: Autoradiography; Basal Ganglia; Brain; Cerebral Cortex; Hippocampus; Humans; Kynurenic Acid; Mesencephalon; Radioligand Assay; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Strychnine; Tritium	1994
Swim stress increases the potency of glycine at the N-methyl-D-aspartate receptor complex. Journal of neurochemistry, 1995, Volume: 64, Issue:2 Topics: Animals; Binding, Competitive; Frontal Lobe; Glycine; Kynurenic Acid; Male; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Stress, Physiological; Swimming	1995
Effects of antagonists at the NMDA receptor complex in two models of anxiety. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1994, Volume: 4, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Anxiety; Behavior, Animal; Conflict, Psychological; Diazepam; Dizocilpine Maleate; Drinking; Electroshock; Exploratory Behavior; Injections, Intraventricular; Kynurenic Acid; Male; Motor Activity; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	1994
Adaptation of the NMDA receptor in rat cortex following chronic electroconvulsive shock or imipramine. European journal of pharmacology, 1993, Nov-15, Volume: 247, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Cerebral Cortex; Electroshock; Glycine; Imipramine; In Vitro Techniques; Kynurenic Acid; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1993
Expression of NMDAR1-1a (N598Q)/NMDAR2A receptors results in decreased cell mortality. European journal of pharmacology, 1994, Feb-15, Volume: 266, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Calcium; Cell Death; Cell Line; Humans; Kynurenic Acid; Mutation; Receptors, N-Methyl-D-Aspartate; Transfection	1994
Prevention by NMDA receptor antagonists of the centrally-evoked increases of cardiac inotropic responses in rabbits. British journal of pharmacology, 1994, Volume: 111, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Blood Pressure; Electric Stimulation; Glutamates; Glutamic Acid; Ketamine; Kynurenic Acid; Male; Myocardial Contraction; Paraventricular Hypothalamic Nucleus; Rabbits; Receptors, N-Methyl-D-Aspartate	1994
Preferential induction by stress of the N-methyl-D-aspartate recognition domain in discrete structures of rat brain. Journal of neurochemistry, 1994, Volume: 63, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Adrenal Cortex Hormones; Animals; Autoradiography; Behavior, Animal; Brain Chemistry; Cerebellum; Corpus Striatum; Cycloheximide; Dizocilpine Maleate; Dose-Response Relationship, Drug; Glycine; Hypothalamus; Kynurenic Acid; Male; N-Methylaspartate; Rats; Rats, Wistar; Stress, Physiological; Tritium	1994
Interaction of felbamate with [3H]DCKA-labeled strychnine-insensitive glycine receptors in human postmortem brain. Experimental neurology, 1994, Volume: 129, Issue:2 Topics: Adult; Aged; Anticonvulsants; Autopsy; Autoradiography; Binding, Competitive; Brain; Felbamate; Female; Glycine; Hippocampus; Humans; Kinetics; Kynurenic Acid; Male; Mesencephalon; Middle Aged; Neurons; Organ Specificity; Phenylcarbamates; Propylene Glycols; Radioligand Assay; Receptors, Glycine; Strychnine; Tritium	1994
Felbamate: interaction with glycine receptors in human cerebral cortex. Proceedings of the Western Pharmacology Society, 1994, Volume: 37 Topics: Adult; Aged; Anticonvulsants; Autoradiography; Cerebral Cortex; Felbamate; Glycine; Humans; Kynurenic Acid; Male; Middle Aged; Phenylcarbamates; Propylene Glycols; Receptors, Glycine; Strychnine	1994
Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Amino Acids; Amino Acids, Cyclic; Animals; Brain; Dizocilpine Maleate; Drug Administration Schedule; Glycine; Imipramine; In Vitro Techniques; Kynurenic Acid; Male; Mice; Receptors, N-Methyl-D-Aspartate	1993
Effects of 5,7 dichlorokynurenic acid on conflict, social interaction and plus maze behaviors. Neuropharmacology, 1993, Volume: 32, Issue:5 Topics: Analysis of Variance; Animals; Anti-Anxiety Agents; Behavior, Animal; Conflict, Psychological; Diazepam; Discrimination Learning; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Social Behavior	1993
Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 269, Issue:1 Topics: Adaptation, Physiological; Animals; Antidepressive Agents; Citalopram; Dose-Response Relationship, Drug; Electroshock; Glycine; Imipramine; Kynurenic Acid; Male; Mice; Receptors, N-Methyl-D-Aspartate; Sensitivity and Specificity; Strychnine; Time Factors; Tritium	1994
Potentiation of N-methyl-D-aspartate-evoked elevation of intracellular Ca2+ concentrations by exogenous glycine in cerebellar granule cells. European journal of pharmacology, 1994, Feb-15, Volume: 266, Issue:3 Topics: Animals; Calcium; Calcium Channel Agonists; Cells, Cultured; Cerebellum; Dizocilpine Maleate; Glycine; Kynurenic Acid; Nicotinic Acids; Oxadiazoles; Rats; Receptors, N-Methyl-D-Aspartate	1994
Ca2+ antagonists effect an antidepressant-like adaptation of the NMDA receptor complex. European journal of pharmacology, 1993, Sep-15, Volume: 247, Issue:1 Topics: Animals; Antidepressive Agents; Binding Sites; Calcium Channel Blockers; Cerebral Cortex; Depression; Diltiazem; Glycine; Kynurenic Acid; Male; Mice; Nimodipine; Receptors, N-Methyl-D-Aspartate	1993
Differential profiles of binding of a radiolabeled agonist and antagonist at a glycine recognition domain on the N-methyl-D-aspartate receptor ionophore complex in rat brain. Journal of neurochemistry, 1994, Volume: 62, Issue:1 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Glycine; Kinetics; Kynurenic Acid; Male; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Synaptic Membranes; Tritium	1994
Evidence for anticonvulsant and neuroprotectant action of felbamate mediated by strychnine-insensitive glycine receptors. The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:3 Topics: Animals; Anticonvulsants; Brain; Dizocilpine Maleate; Felbamate; Female; In Vitro Techniques; Kynurenic Acid; Male; Neurons; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, Neurotransmitter; Strychnine	1993
Excitatory amino acid receptor antagonists and naloxone-precipitated withdrawal syndrome in morphine-dependent mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1993, Volume: 3, Issue:2 Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Glycine; Kynurenic Acid; Male; Mice; Morphine Dependence; Naloxone; Quinoxalines; Receptors, Amino Acid; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Receptors, Neurotransmitter; Substance Withdrawal Syndrome	1993
Support for radiolabeling of a glycine recognition domain on the N-methyl-D-aspartate receptor ionophore complex by 5,7-[3H]dichlorokynurenate in rat brain. Journal of neurochemistry, 1993, Volume: 60, Issue:2 Topics: Animals; Binding Sites; Binding, Competitive; Brain; Glycine; Kinetics; Kynurenic Acid; Male; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Substrate Specificity; Synaptic Membranes; Tritium	1993
Kynurenic acid and 5,7-dichlorokynurenic acids improve social and object recognition in male rats. Psychopharmacology, 1995, Volume: 120, Issue:4 Topics: Animals; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Habituation, Psychophysiologic; Kynurenic Acid; Male; Memory, Short-Term; Rats; Rats, Wistar; Social Identification; Time Factors	1995
Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL-82.0715). Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:3 Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Antidepressive Agents; Behavior, Animal; Biogenic Polyamines; Brain Chemistry; Down-Regulation; Excitatory Amino Acid Antagonists; Glycine; Imipramine; Kynurenic Acid; Male; Mice; Mice, Inbred C57BL; Motor Activity; Piperidines; Receptors, Glycine	1995
Effects of felbamate, kynurenic acid derivatives and NMDA antagonists on in vitro kainate-induced epileptiform activity. Life sciences, 1996, May-24, Volume: 58, Issue:26 Topics: Animals; Anticonvulsants; Excitatory Amino Acid Antagonists; Felbamate; Hippocampus; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar	1996
Regionally distinct stoichiometry for N-methyl-D-aspartate receptor domains in brain. Neuroreport, 1996, Feb-29, Volume: 7, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Animals; Brain; Brain Chemistry; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kinetics; Kynurenic Acid; Male; Nerve Tissue Proteins; Radioligand Assay; Rats; Rats, Inbred F344; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	1996
Neuroprotective effects of RPR 104632, a novel antagonist at the glycine site of the NMDA receptor, in vitro. European journal of pharmacology, 1996, Apr-11, Volume: 300, Issue:3 Topics: Aminoquinolines; Animals; Benzothiadiazines; Binding, Competitive; Cerebral Cortex; Cyclic GMP; Excitatory Amino Acid Antagonists; Hippocampus; In Vitro Techniques; Kynurenic Acid; Nerve Degeneration; Phencyclidine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1996
Synthesis and structure-activity relationships of 1,2,3,4-tetrahydroquinoline-2,3,4-trione 3-oximes: novel and highly potent antagonists for NMDA receptor glycine site. Journal of medicinal chemistry, 1996, Aug-16, Volume: 39, Issue:17 Topics: Animals; Brain; Cell Membrane; Cerebral Cortex; Cloning, Molecular; Excitatory Amino Acid Antagonists; Female; Glycine; Kinetics; Kynurenic Acid; Magnetic Resonance Spectroscopy; Molecular Structure; Oocytes; Oximes; Quinolines; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Structure-Activity Relationship; Xenopus	1996
Excitoprotective effect of felbamate in cultured cortical neurons. Brain research, 1995, Dec-24, Volume: 705, Issue:1-2 Topics: Animals; Anticonvulsants; Binding Sites; Calcium; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Felbamate; Glycine; Kainic Acid; Kynurenic Acid; N-Methylaspartate; Neurons; Neuroprotective Agents; Neurotoxins; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Strychnine	1995
NMDA receptor antagonists block development of tolerance to m-CPP-induced increases in ACTH concentrations in rats. European journal of pharmacology, 1996, Jul-25, Volume: 308, Issue:3 Topics: Adrenocorticotropic Hormone; Animals; Dimethyl Sulfoxide; Dizocilpine Maleate; Drug Tolerance; Kynurenic Acid; Male; Phencyclidine; Piperazines; Piperidines; Pyrrolidinones; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Serotonin Receptor Agonists	1996
High level expression of the NMDAR1 glutamate receptor subunit in electroporated COS cells. Journal of neurochemistry, 1996, Volume: 67, Issue:4 Topics: Animals; beta-Galactosidase; Binding, Competitive; Calcium; Cell Line; Chlorocebus aethiops; COS Cells; Electroporation; Excitatory Amino Acid Antagonists; Glycine; Humans; Kidney; Kinetics; Kynurenic Acid; Macromolecular Substances; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Serine; Stereoisomerism; Transfection	1996
[3H]MDL 105,519, a high-affinity radioligand for the N-methyl-D-aspartate receptor-associated glycine recognition site. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:1 Topics: Animals; Binding Sites; Glycine; Hydrogen-Ion Concentration; Indoles; Kynurenic Acid; Ligands; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	1996
Overexpression of a functional NMDA receptor subunit (NMDAR1) in baculovirus-infected Trichoplusia ni insect cells. Brain research. Molecular brain research, 1996, Sep-05, Volume: 41, Issue:1-2 Topics: Animals; Binding Sites; Cell Line; Chromatography, Affinity; DNA, Complementary; Electrophysiology; Gene Expression Regulation, Viral; Genetic Vectors; Glycosylation; Histidine; Kynurenic Acid; Moths; Nickel; Nucleopolyhedroviruses; Oocytes; Protein Processing, Post-Translational; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Transfection; Tunicamycin; Xenopus laevis	1996
Differential effects of five glycine site antagonists on NMDA receptor desensitisation. European journal of pharmacology, 1996, Sep-12, Volume: 311, Issue:2-3 Topics: Animals; Benzothiadiazines; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; N-Methylaspartate; Neurons; Patch-Clamp Techniques; Quinolones; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1996
Reduction in the mechanonociceptive response by intrathecal administration of glycine and related compounds. Neurochemical research, 1996, Volume: 21, Issue:10 Topics: Animals; Cerebrospinal Fluid; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Injections, Spinal; Kynurenic Acid; Male; Mechanoreceptors; Neuralgia; Nociceptors; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Strychnine; Transcutaneous Electric Nerve Stimulation	1996
Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 279, Issue:2 Topics: Animals; Calcium; Cell Survival; CHO Cells; Cricetinae; Dizocilpine Maleate; Kynurenic Acid; L-Lactate Dehydrogenase; Luciferases; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Transfection	1996
Anticonvulsant activity of 5,7DCKA, NBQX, and felbamate against some chemoconvulsants in DBA/2 mice. Pharmacology, biochemistry, and behavior, 1996, Volume: 55, Issue:2 Topics: Acoustic Stimulation; Animals; Anticonvulsants; Behavior, Animal; Convulsants; Electroshock; Excitatory Amino Acid Antagonists; Felbamate; Female; Injections, Intraventricular; Ion Channel Gating; Kynurenic Acid; Male; Mice; Mice, Inbred DBA; Motor Activity; Phenylcarbamates; Potassium Channels; Propylene Glycols; Quinoxalines	1996
Structure-activity relationships of alkyl- and alkoxy-substituted 1,4-dihydroquinoxaline-2,3-diones: potent and systemically active antagonists for the glycine site of the NMDA receptor. Journal of medicinal chemistry, 1997, Feb-28, Volume: 40, Issue:5 Topics: Animals; Anticonvulsants; Binding Sites; Binding, Competitive; Cerebral Cortex; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; Oocytes; Quinoxalines; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Structure-Activity Relationship; Xenopus	1997
Partition of transient and sustained inhibitory glycinergic input to retinal ganglion cells. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, May-15, Volume: 17, Issue:10 Topics: Alanine; Ambystoma; Animals; Electrophysiology; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Kynurenic Acid; Receptors, Glycine; Retinal Ganglion Cells; Serine; Strychnine; Synaptic Transmission; Taurine	1997
Antagonism of convulsions but failure to enhance GABA(A) receptor function by felbamate in mice tolerant to diazepam. Neurochemical research, 1997, Volume: 22, Issue:6 Topics: Animals; Anticonvulsants; Diazepam; Down-Regulation; Drug Evaluation, Preclinical; Drug Tolerance; Excitatory Amino Acid Antagonists; Felbamate; GABA Modulators; Isoniazid; Kynurenic Acid; Male; Mice; Phenylcarbamates; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Time Factors	1997
Characterization of 5,7-dichlorokynurenate-insensitive D-[3H]serine binding to synaptosomal fraction isolated from rat brain tissues. Journal of neurochemistry, 1997, Volume: 69, Issue:1 Topics: Animals; Binding Sites; Binding, Competitive; Brain Chemistry; Cations; Cerebellum; Cerebral Cortex; Detergents; Excitatory Amino Acid Antagonists; Glycine; Kidney; Kynurenic Acid; Liver; Male; Octoxynol; Rats; Rats, Wistar; Serine; Subcellular Fractions; Synaptosomes; Tritium	1997
Comparing long-term depression with pharmacologically induced synaptic attenuations in young rat hippocampi. Synapse (New York, N.Y.), 1997, Volume: 26, Issue:4 Topics: 2-Amino-5-phosphonovalerate; 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Dizocilpine Maleate; Evoked Potentials; Excitatory Amino Acid Antagonists; Hippocampus; Kynurenic Acid; Male; Neuronal Plasticity; Neurotransmitter Agents; Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Receptors, Presynaptic; Synapses	1997
A partial agonist model used in the allosteric modulation of the NMDA receptor. European journal of pharmacology, 1997, Jun-11, Volume: 328, Issue:2-3 Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Cerebellum; Cerebral Cortex; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Hippocampus; In Vitro Techniques; Kynurenic Acid; Male; Models, Biological; Protein Binding; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1997
Competitive NMDA and strychnine-insensitive glycine-site antagonists disrupt prepulse inhibition. Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4 Topics: Acoustic Stimulation; Animals; Binding, Competitive; Depression, Chemical; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Motor Activity; Phencyclidine; Pipecolic Acids; Rats; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Startle; Synaptic Transmission	1997
EMD 95885, a new eliprodil analogue with higher affinity for the N-methyl-D-aspartate (NMDA) receptor. Die Pharmazie, 1997, Volume: 52, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Animals; Binding, Competitive; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; Piperidines; Radioligand Assay; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	1997
Gp120 can revert antagonism at the glycine site of NMDA receptors mediating GABA release from cultured hippocampal neurons. Journal of neuroscience research, 1997, Sep-15, Volume: 49, Issue:6 Topics: Animals; Binding Sites; Cells, Cultured; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; gamma-Aminobutyric Acid; Glycine; Hippocampus; HIV Envelope Protein gp120; HIV-1; Kynurenic Acid; N-Methylaspartate; Neurons; Rats; Receptors, N-Methyl-D-Aspartate; Tritium	1997
Modulation of neuronal mitochondrial membrane potential by the NMDA receptor: role of arachidonic acid. Brain research, 1997, Nov-28, Volume: 777, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Anesthetics, Local; Animals; Arachidonic Acid; Biomarkers; Cells, Cultured; Cerebellum; Dibucaine; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Flow Cytometry; Fluorescent Dyes; Glycine; Intracellular Membranes; Kynurenic Acid; Membrane Potentials; Mitochondria; N-Methylaspartate; Piperidines; Quinacrine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Rhodamine 123; Rhodamines; Sulfonamides	1997
Functional characterization of human N-methyl-D-aspartate subtype 1A/2D receptors. Journal of neurochemistry, 1998, Volume: 70, Issue:3 Topics: Animals; Calcium; Cells, Cultured; DNA, Complementary; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Glycine; Humans; Kidney; Kynurenic Acid; Membrane Potentials; Molecular Sequence Data; N-Methylaspartate; Oocytes; Patch-Clamp Techniques; Pipecolic Acids; Piperidines; Receptors, N-Methyl-D-Aspartate; Recombinant Proteins; Sequence Homology, Amino Acid; Serine; Xenopus laevis	1998
Protein kinases modulate two glycine currents in salamander retinal ganglion cells. The Journal of physiology, 1998, May-01, Volume: 508 ( Pt 3) Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Ambystoma; Animals; Colforsin; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Isoquinolines; Kinetics; Kynurenic Acid; Membrane Potentials; Patch-Clamp Techniques; Phosphodiesterase Inhibitors; Protein Kinase C; Retinal Ganglion Cells; Strychnine; Sulfonamides	1998
Effects of the novel tricyclic quinoxalinedione derivatives, SM-18400 and its analogs, on N-methyl-D-aspartate (NMDA) receptor-mediated synaptic transmission in the isolated neonatal rat spinal cord in vitro. Japanese journal of pharmacology, 1998, Volume: 76, Issue:3 Topics: Aminoquinolines; Animals; Animals, Newborn; Excitatory Amino Acid Antagonists; In Vitro Techniques; Kynurenic Acid; Male; Quinoxalines; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reflex; Serine; Spinal Cord; Synaptic Transmission	1998
Felbamate increases [3H]glycine binding in rat brain and sections of human postmortem brain. The Journal of pharmacology and experimental therapeutics, 1998, Volume: 286, Issue:2 Topics: Animals; Anticonvulsants; Autoradiography; Brain Chemistry; Excitatory Amino Acid Antagonists; Felbamate; Glycine; Humans; Kynurenic Acid; Male; Phenylcarbamates; Postmortem Changes; Propylene Glycols; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	1998
Plasticity of agonist binding sites in hetero-oligomers of the unitary glutamate receptor subunit XenU1. Journal of neurochemistry, 1998, Volume: 71, Issue:3 Topics: Animals; Binding Sites; Brain; Cell Membrane; COS Cells; Guanosine Triphosphate; Kainic Acid; Kynurenic Acid; Precipitin Tests; Receptors, Glutamate; Xenopus; Xenopus Proteins	1998
Molecular and pharmacological characterization of recombinant rat/mice N-methyl-D-aspartate receptor subtypes in the yeast Saccharomyces cerevisiae. European journal of biochemistry, 1998, Sep-01, Volume: 256, Issue:2 Topics: Animals; Carbodiimides; Cell Membrane; Cloning, Molecular; Cycloleucine; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Gene Expression; Glutamic Acid; Indoles; Kynurenic Acid; Mice; Microscopy, Fluorescence; Protein Binding; Rats; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Recombinant Proteins; RNA, Messenger; Saccharomyces cerevisiae; Transformation, Genetic	1998
Complex polyamine effects on [3H]MDL 105,519 binding to the NMDA receptor glycine site. Neurochemistry international, 1998, Volume: 33, Issue:2 Topics: Aminoquinolines; Animals; Binding Sites; Binding, Competitive; Brain; Cell Membrane; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glycine; Indoles; Kynurenic Acid; Polyamines; Rats; Receptors, N-Methyl-D-Aspartate; Spermidine; Spermine; Tritium	1998
The role of striatal glutamate receptors in models of Parkinson's disease. Amino acids, 1998, Volume: 14, Issue:1-3 Topics: Animals; Corpus Striatum; Disease Models, Animal; Dizocilpine Maleate; Electromyography; Excitatory Amino Acid Antagonists; Haloperidol; Kynurenic Acid; Parkinson Disease; Quinolones; Rats; Receptors, N-Methyl-D-Aspartate; Reserpine	1998
Ferrous iron modulates quinolinate-mediated [3H]MK-801 binding to rat brain synaptic membranes in the presence of glycine and spermidine. Neuroscience letters, 1999, Mar-05, Volume: 262, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Allosteric Regulation; Animals; Binding Sites; Brain; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Ferrous Compounds; Glutamic Acid; Glycine; Inhibitory Concentration 50; Kynurenic Acid; Male; Quinolinic Acid; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spermidine; Synaptic Membranes	1999
N-methyl-D-asparate receptor antagonists abolish the maintenance phase of self-sustaining status epilepticus in rat. Neuroscience letters, 1999, Apr-23, Volume: 265, Issue:3 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Action Potentials; Animals; Anticonvulsants; Disease Models, Animal; Dizocilpine Maleate; Electric Stimulation; Excitatory Amino Acid Antagonists; Hippocampus; Ketamine; Kynurenic Acid; Male; Perforant Pathway; Rats; Rats, Wistar; Receptors, AMPA; Receptors, Kainic Acid; Receptors, N-Methyl-D-Aspartate; Status Epilepticus	1999
A mutation in the glycine binding pocket of the N-methyl-D-aspartate receptor NR1 subunit alters agonist efficacy. Brain research. Molecular brain research, 1999, Nov-10, Volume: 73, Issue:1-2 Topics: Animals; Binding Sites; Binding, Competitive; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glycine; Kynurenic Acid; Mice; Mutation; Oocytes; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Xenopus laevis	1999
Noradrenergic lesion antagonizes desipramine-induced adaptation of NMDA receptors. European journal of pharmacology, 2000, Feb-18, Volume: 389, Issue:2-3 Topics: Adaptation, Physiological; Animals; Antidepressive Agents, Tricyclic; Benzylamines; Cerebral Cortex; Desipramine; Fluoxetine; Glycine; Kynurenic Acid; Male; Mice; Norepinephrine; Receptors, N-Methyl-D-Aspartate	2000
Differential effects of NMDA-receptor antagonists on long-term potentiation and hypoxic/hypoglycaemic excitotoxicity in hippocampal slices. Neuropharmacology, 2000, Feb-14, Volume: 39, Issue:4 Topics: 2-Amino-5-phosphonovalerate; Animals; Cell Hypoxia; Cells, Cultured; Excitatory Amino Acid Antagonists; Glucose; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Male; Neurons; Patch-Clamp Techniques; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	2000
Chronic glycine treatment desensitizes the behavioral response to 1-aminocyclopropanecarboxylic acid (ACPC), a partial agonist at the strychnine-insensitive glycine site of the NMDA receptor complex. Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:2 Topics: Amino Acids; Amino Acids, Cyclic; Animals; Behavior, Animal; Binding Sites; Cerebral Cortex; Glycine; Hippocampus; Kynurenic Acid; Male; Mice; Psychomotor Performance; Radioligand Assay; Receptors, N-Methyl-D-Aspartate; Strychnine; Tritium	2000
Chronic treatment with antidepressants affects glycine/NMDA receptor function: behavioral evidence. Neuropharmacology, 2000, Volume: 39, Issue:12 Topics: Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; Chlordiazepoxide; Dose-Response Relationship, Drug; Electroshock; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Mice; Quinolones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate	2000
A novel series of 2-carboxytetrahydroquinolines provides new insights into the eastern region of glycine site NMDA antagonists. Archiv der Pharmazie, 2000, Volume: 333, Issue:8 Topics: Animals; Binding Sites; Brain; Cell Membrane; Ethers, Cyclic; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; Patch-Clamp Techniques; Quinolines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Urea	2000
Effects of reboxetine and sertraline treatments alone and in combination on the binding properties of cortical NMDA and beta1-adrenergic receptors in an animal model of depression. Journal of neural transmission (Vienna, Austria : 1996), 2000, Volume: 107, Issue:10 Topics: Adrenergic beta-Antagonists; Adrenergic Uptake Inhibitors; Animals; Cerebral Cortex; Depressive Disorder; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Kynurenic Acid; Male; Morpholines; Neurons; Norepinephrine; Propanolamines; Rats; Rats, Sprague-Dawley; Reboxetine; Receptors, Adrenergic, beta-1; Receptors, N-Methyl-D-Aspartate; Serotonin; Sertraline	2000
Effect of extracellular long-time microperfusion of high concentrations of glutamate and glycine on picrotoxin seizure thresholds in the hippocampus of freely moving rats. Brain research, 2001, Jan-05, Volume: 888, Issue:1 Topics: Animals; Epilepsy; Excitatory Amino Acid Antagonists; Extracellular Space; GABA Antagonists; Glutamic Acid; Glycine; Hippocampus; Kynurenic Acid; Male; Microdialysis; Motor Activity; Neural Inhibition; Picrotoxin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Seizures	2001
Attenuation of morphine dependence and withdrawal by glycine B site antagonists in rats. Pharmacology, biochemistry, and behavior, 2001, Volume: 68, Issue:1 Topics: Animals; Behavior, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Implants; Excitatory Amino Acid Antagonists; Glycine Agents; Kynurenic Acid; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Quinolones; Rats; Rats, Wistar; Receptors, Glycine; Substance Withdrawal Syndrome	2001
Conjugation with L-Glutamate for in vivo brain drug delivery. Journal of drug targeting, 2001, Volume: 9, Issue:1 Topics: Animals; Antineoplastic Agents, Alkylating; Blood-Brain Barrier; Brain; Capillary Permeability; Drug Delivery Systems; Drug Evaluation; Endorphins; Glutamic Acid; Kynurenic Acid; Male; Melphalan; Phenylalanine; Prodrugs; Rats; Rats, Wistar	2001
Ethanol inhibition of N-methyl-D-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue. The Journal of biological chemistry, 2001, Nov-30, Volume: 276, Issue:48 Topics: Amino Acid Sequence; Animals; Binding, Competitive; Cell Line; Dose-Response Relationship, Drug; Ethanol; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Humans; Kynurenic Acid; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Patch-Clamp Techniques; Phenylalanine; Protein Binding; Protein Structure, Tertiary; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Transfection; Xenopus laevis	2001
Role of spinal NMDA receptors, protein kinase C and nitric oxide synthase in the hyperalgesia induced by magnesium deficiency in rats. British journal of pharmacology, 2001, Volume: 134, Issue:6 Topics: 2-Amino-5-phosphonovalerate; Alkaloids; Analgesics; Animals; Benzophenanthridines; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Hyperalgesia; Indazoles; Injections, Spinal; Kynurenic Acid; Magnesium Sulfate; Male; Neurons; Nitric Oxide Synthase; Pain Measurement; Phenanthridines; Protein Kinase C; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Spine	2001
Vasodilatory N-methyl-D-aspartate receptors are constitutively expressed in rat kidney. Journal of the American Society of Nephrology : JASN, 2002, Volume: 13, Issue:5 Topics: Analysis of Variance; Animals; Dizocilpine Maleate; DNA, Complementary; Glomerular Filtration Rate; Glycine; Hemodynamics; Immunohistochemistry; Kidney Cortex; Kynurenic Acid; Male; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Renal Circulation; Reverse Transcriptase Polymerase Chain Reaction	2002
In vitro and in vivo antagonistic activities of SM-31900 for the NMDA receptor glycine-binding site. Brain research, 2002, Jul-19, Volume: 944, Issue:1-2 Topics: Aminoquinolines; Animals; Binding, Competitive; Brain; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Indoles; Kynurenic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Seizures	2002
Differential alterations in the expression of NMDA receptor subunits following chronic ethanol treatment in primary cultures of rat cortical and hippocampal neurones. Neurochemistry international, 2003, Volume: 42, Issue:1 Topics: Animals; Animals, Newborn; Cells, Cultured; Cerebral Cortex; Culture Media, Serum-Free; Dizocilpine Maleate; Ethanol; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Hippocampus; Kynurenic Acid; N-Methylaspartate; Nerve Tissue Proteins; Neurons; Piperidines; Protein Subunits; Rats; Receptors, N-Methyl-D-Aspartate; RNA Splicing	2003
Synthesis and SAR of novel di- and trisubstituted 1,4-dihydroquinoxaline-2,3-diones related to licostinel (Acea 1021) as NMDA/glycine site antagonists. Bioorganic & medicinal chemistry, 2003, Apr-17, Volume: 11, Issue:8 Topics: Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Glycine; Inhibitory Concentration 50; Kynurenic Acid; Quinoxalines; Radioligand Assay; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship	2003
Human immunodeficiency virus type 1 Tat protein directly activates neuronal N-methyl-D-aspartate receptors at an allosteric zinc-sensitive site. Journal of neurovirology, 2003, Volume: 9, Issue:3 Topics: 2-Amino-5-phosphonovalerate; Action Potentials; Allosteric Regulation; Allosteric Site; Animals; Excitatory Amino Acid Antagonists; Gene Products, tat; Hippocampus; HIV-1; Humans; Ketamine; Kynurenic Acid; Neurons; Patch-Clamp Techniques; Protein Interaction Mapping; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; tat Gene Products, Human Immunodeficiency Virus; Zinc	2003
Mechanisms of activation, inhibition and specificity: crystal structures of the NMDA receptor NR1 ligand-binding core. The EMBO journal, 2003, Jun-16, Volume: 22, Issue:12 Topics: Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Disulfides; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Models, Molecular; Molecular Sequence Data; Molecular Structure; Protein Binding; Protein Conformation; Protein Subunits; Rats; Receptors, AMPA; Receptors, N-Methyl-D-Aspartate; Sequence Alignment; Serine	2003
Evidence for a glutamatergic modulation of the cholinergic function in the human enteric nervous system via NMDA receptors. European journal of pharmacology, 2003, Aug-22, Volume: 476, Issue:1-2 Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Aged; Colon, Ascending; Colon, Sigmoid; Enteric Nervous System; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Glutamic Acid; Humans; Immunohistochemistry; In Vitro Techniques; Kynurenic Acid; Male; Muscle, Smooth; N-Methylaspartate; Neurons; Receptors, N-Methyl-D-Aspartate	2003
Selective antagonism of rat inhibitory glycine receptor subunits. The Journal of physiology, 2004, Feb-01, Volume: 554, Issue:Pt 3 Topics: Animals; Arginine; Cell Line; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Glycine; Glycine Agents; Humans; Kynurenic Acid; Mutation; Osmolar Concentration; Rats; Receptors, Glycine; Strychnine	2004
Model structures of the N-methyl-D-aspartate receptor subunit NR1 explain the molecular recognition of agonist and antagonist ligands. Journal of structural biology, 2004, Volume: 145, Issue:3 Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Crystallography, X-Ray; Cycloserine; Databases as Topic; Escherichia coli; Excitatory Amino Acid Antagonists; Glycine; Humans; Hydrogen Bonding; Indoles; Kynurenic Acid; Ligands; Mice; Models, Chemical; Models, Molecular; Molecular Sequence Data; Potassium Channels; Proline; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Rats; Receptors, AMPA; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Sequence Homology, Amino Acid; Serine; Threonine; Tryptophan; Water	2004
Memantine inhibits and reverses the Alzheimer type abnormal hyperphosphorylation of tau and associated neurodegeneration. FEBS letters, 2004, May-21, Volume: 566, Issue:1-3 Topics: 2-Amino-5-phosphonovalerate; Alzheimer Disease; Animals; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Kynurenic Acid; Memantine; Microtubule-Associated Proteins; Nerve Degeneration; Neurofibrils; Neuroprotective Agents; Okadaic Acid; Phosphoprotein Phosphatases; Phosphorylation; Rats; Rats, Wistar; tau Proteins	2004
Putative NMDA receptors in Hydra: a biochemical and functional study. The European journal of neuroscience, 2004, Volume: 20, Issue:10 Topics: 2-Amino-5-phosphonovalerate; Animals; Behavior, Animal; Binding Sites; Cell Membrane; Concanavalin A; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Feeding Behavior; Glutamic Acid; Glutathione; Glycine; Hydra; Kynurenic Acid; N-Methylaspartate; Receptors, N-Methyl-D-Aspartate; Serine; Strychnine	2004
Schwann cells exhibit excitotoxicity consistent with release of NMDA receptor agonists. Journal of neuroscience research, 2005, Mar-01, Volume: 79, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Analysis of Variance; Animals; Calcium; Cell Death; Cells, Cultured; Culture Media, Conditioned; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Fluorescent Antibody Technique; Glutamic Acid; Hippocampus; Kynurenic Acid; Microtubule-Associated Proteins; Nerve Degeneration; Neurons; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Schwann Cells; Tetrazolium Salts; Thiazoles; Time Factors	2005
D-serine enhances impaired long-term potentiation in CA1 subfield of hippocampal slices from aged senescence-accelerated mouse prone/8. Neuroscience letters, 2005, Apr-29, Volume: 379, Issue:1 Topics: Age Factors; Aging; Analysis of Variance; Animals; D-Amino-Acid Oxidase; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Kynurenic Acid; Long-Term Potentiation; Mice; Mice, Neurologic Mutants; Serine; Valine	2005
Antiallodynic effects of NMDA glycine(B) antagonists in neuropathic pain: possible peripheral mechanisms. Brain research, 2005, Jun-28, Volume: 1048, Issue:1-2 Topics: Action Potentials; Animals; Constriction, Pathologic; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Routes; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Kynurenic Acid; Ligation; Male; N-Methylaspartate; Neuralgia; Neurons, Afferent; Pain Measurement; Quinolones; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Nerves; Time Factors	2005
Contribution of endogenous glycine site NMDA agonists to excitotoxic retinal damage in vivo. Neuroscience research, 2006, Volume: 56, Issue:3 Topics: Amidohydrolases; Animals; Cell Death; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glycine; Kynurenic Acid; Male; N-Methylaspartate; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Retinal Diseases; Retinal Ganglion Cells; Serine	2006
Modulation of glycine potency in rat recombinant NMDA receptors containing chimeric NR2A/2D subunits expressed in Xenopus laevis oocytes. The Journal of physiology, 2008, Jan-01, Volume: 586, Issue:1 Topics: Amino Acid Sequence; Animals; Chimera; Dose-Response Relationship, Drug; Electrophysiology; Excitatory Amino Acid Antagonists; Female; Glycine; Kynurenic Acid; Molecular Sequence Data; Oocytes; Patch-Clamp Techniques; Rats; Receptors, N-Methyl-D-Aspartate; RNA, Complementary; Xenopus laevis	2008
The integrity of the glycine co-agonist binding site of N-methyl-D-aspartate receptors is a functional quality control checkpoint for cell surface delivery. The Journal of biological chemistry, 2009, Jan-02, Volume: 284, Issue:1 Topics: Amino Acid Motifs; Binding Sites; Cell Line; Cell Membrane; Endoplasmic Reticulum; Excitatory Amino Acid Antagonists; Gene Expression Regulation; Glycine; Humans; Kynurenic Acid; Point Mutation; Protein Binding; Protein Structure, Tertiary; Protein Subunits; Protein Transport; Receptors, N-Methyl-D-Aspartate	2009
Kinetic basis of partial agonism at NMDA receptors. Nature neuroscience, 2009, Volume: 12, Issue:9 Topics: Action Potentials; Alanine; Amino Acids, Cyclic; Animals; Binding Sites; Cell Line; Cell Membrane; Cycloserine; Excitatory Amino Acid Agents; Glutamates; Glutamic Acid; Glycine; Humans; Kinetics; Kynurenic Acid; Models, Molecular; Rats; Receptors, N-Methyl-D-Aspartate	2009
Intracisternal administration of NR2 antagonists attenuates facial formalin-induced nociceptive behavior in rats. Journal of orofacial pain, 2010,Spring, Volume: 24, Issue:2 Topics: Animals; Behavior, Animal; Cisterna Magna; Disease Models, Animal; Excitatory Amino Acid Antagonists; Facial Pain; Formaldehyde; Injections; Injections, Subcutaneous; Kynurenic Acid; Male; Memantine; Motor Activity; Nociceptors; Phenols; Piperazines; Piperidines; Pruritus; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Time Factors; Vibrissae	2010
Protein kinase C modulates NMDA receptors in the myenteric plexus of the guinea pig ileum during in vitro ischemia and reperfusion. Neurogastroenterology and motility, 2011, Volume: 23, Issue:2 Topics: 2-Amino-5-phosphonovalerate; Animals; Benzophenanthridines; Guinea Pigs; Ileum; In Vitro Techniques; Isoquinolines; Kynurenic Acid; Male; Models, Animal; Myenteric Plexus; Phosphorylation; Protein Kinase C; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Sulfonamides	2011
Peripheral administration of NR2 antagonists attenuates orofacial formalin-induced nociceptive behavior in rats. Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jun-01, Volume: 35, Issue:4 Topics: Animals; Behavior, Animal; Excitatory Amino Acid Antagonists; Facial Pain; Injections; Kynurenic Acid; Male; Memantine; Pain Measurement; Phenols; Piperidines; Postural Balance; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Vibrissae	2011
Arrangement of subunits in functional NMDA receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Aug-03, Volume: 31, Issue:31 Topics: 4-Aminopyridine; Amino Acid Motifs; Analysis of Variance; Animals; Cell Line, Transformed; Copper Sulfate; Cysteine; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Glycine; Humans; Kynurenic Acid; Membrane Potentials; Microinjections; Models, Molecular; Mutagenesis; Mutation; Oocytes; Patch-Clamp Techniques; Protein Structure, Tertiary; Protein Subunits; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Statistics, Nonparametric; Transfection; Xenopus	2011
Probing the modulation of acute ethanol intoxication by pharmacological manipulation of the NMDAR glycine co-agonist site. Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:2 Topics: Alcoholic Intoxication; Animals; Ataxia; Cycloserine; Disease Models, Animal; Disks Large Homolog 4 Protein; Dizocilpine Maleate; Drug Therapy, Combination; Glycine Plasma Membrane Transport Proteins; Guanylate Kinases; Hypothermia; Kynurenic Acid; Magnesium; Male; Membrane Proteins; Mice; Mice, 129 Strain; Mice, Inbred C57BL; Mice, Knockout; Quinolones; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Reflex, Righting; Sarcosine; Serine	2013
The neuroprotector kynurenic acid increases neuronal cell survival through neprilysin induction. Neuropharmacology, 2013, Volume: 70 Topics: Animals; Cell Survival; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Gene Expression; Humans; Kynurenic Acid; Mice; Neprilysin; Neurons; Neuroprotective Agents; Primary Cell Culture; Receptors, N-Methyl-D-Aspartate; Thiorphan	2013
A new function for glycine GlyT2 transporters: Stimulation of γ-aminobutyric acid release from cerebellar nerve terminals through GAT1 transporter reversal and Ca(2+)-dependent anion channels. Journal of neuroscience research, 2014, Volume: 92, Issue:3 Topics: Analysis of Variance; Animals; Calcium; Calcium Channel Blockers; Cerebellum; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; GABA Agents; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Glycine Plasma Membrane Transport Proteins; Kynurenic Acid; Male; Mice; Nerve Tissue Proteins; Nipecotic Acids; Synaptosomes; Tritium	2014
Intracellular calcium elevation during plateau potentials mediated by extrasynaptic NMDA receptor activation in rat hippocampal CA1 pyramidal neurons is primarily due to calcium entry through voltage-gated calcium channels. The European journal of neuroscience, 2014, Volume: 39, Issue:10 Topics: Aniline Compounds; Animals; CA1 Region, Hippocampal; Cadmium; Calcium; Calcium Channels; Excitatory Amino Acid Antagonists; Fluorescent Dyes; Intracellular Space; Kynurenic Acid; Magnesium; Male; Membrane Potentials; Optical Imaging; Patch-Clamp Techniques; Pyramidal Cells; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Sodium Channel Blockers; Synapses; Tetrodotoxin; Tissue Culture Techniques; Xanthenes	2014
Differential regulation of NMDA receptors by d-serine and glycine in mammalian spinal locomotor networks. Journal of neurophysiology, 2017, 05-01, Volume: 117, Issue:5 Topics: 2-Amino-5-phosphonovalerate; Animals; Efferent Pathways; Glycine; Interneurons; Kynurenic Acid; Mice; Mice, Inbred C57BL; Motor Activity; Racemases and Epimerases; Receptors, N-Methyl-D-Aspartate; Sarcosine; Serine; Spinal Nerve Roots; Synapses	2017