5,7-dichlorokynurenic acid has been researched along with 7-chlorokynurenic acid in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (72.73) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baker, R; Carling, RW; Foster, AC; Grimwood, S; Kemp, JA; Leeson, PD; Marshall, GR; Moseley, AM | 1 |
| Baker, R; Carling, RW; Curtis, NR; Donald, AE; Foster, AC; Kemp, JA; Leeson, PD; Marshall, GR; Moore, KW; Williams, BJ | 1 |
| Baron, BM; Harrison, BL; McDonald, IA; Nyce, PL; Salituro, FG; Stewart, KT | 1 |
| Baron, BM; Cousino, DM; Harrison, BL; McDonald, IA | 1 |
| Iversen, LL; Leeson, PD | 1 |
| Baker, R; Carling, RW; Foster, AC; Grimwood, S; Hargreaves, R; Hurley, C; Kemp, JA; Kulagowski, JJ; Leeson, PD; Marshall, GR; Rathbone, D; Rowley, M; Saywell, KL; Stevenson, GI; Tricklebank, MD; Watt, AP | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Lodge, D; Millar, JD; Pralong, E | 1 |
| Domenici, MR; Marinelli, S; Sagratella, S | 1 |
| Ito, A; Nagata, R; Nakamura, M; Ohtani, K; Tanaka, H; Yasuda, H; Yoneda, Y | 1 |
| Bihel, F; Bourguignon, JJ; Klein, C; Maitre, M; Mensah-Nyagan, AG; Patte-Mensah, C; Schmitt, M; Taleb, O | 1 |
1 review(s) available for 5,7-dichlorokynurenic acid and 7-chlorokynurenic acid
| Article | Year |
|---|---|
The glycine site on the NMDA receptor: structure-activity relationships and therapeutic potential.
Topics: Animals; Anti-Anxiety Agents; Antipsychotic Agents; Binding Sites; Cognition; Glycine; Humans; Kynurenic Acid; Neuroprotective Agents; Pyrrolidinones; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1994 |
10 other study(ies) available for 5,7-dichlorokynurenic acid and 7-chlorokynurenic acid
| Article | Year |
|---|---|
2-Carboxytetrahydroquinolines. Conformational and stereochemical requirements for antagonism of the glycine site on the NMDA receptor.
Topics: Animals; Binding Sites; Cell Membrane; Cerebral Cortex; Glycine; Hippocampus; Kynurenic Acid; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Quinolines; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; X-Ray Diffraction | 1992 |
Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor.
Topics: Animals; Binding, Competitive; Glycine; Indicators and Reagents; Kynurenic Acid; Molecular Structure; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship | 1991 |
3-(2-carboxyindol-3-yl)propionic acid derivatives: antagonists of the strychnine-insensitive glycine receptor associated with the N-methyl-D-aspartate receptor complex.
Topics: Animals; Binding Sites; Binding, Competitive; Cerebral Cortex; Glycine; Hippocampus; Indoles; Molecular Structure; N-Methylaspartate; Propionates; Rats; Receptors, N-Methyl-D-Aspartate; Structure-Activity Relationship; Strychnine | 1990 |
4-[(Carboxymethyl)oxy]- and 4-[(carboxymethyl)amino]-5,7-dichloroquinoline-2-carboxylic acid: new antagonists of the strychnine-insensitive glycine binding site on the N-methyl-D-aspartate receptor complex.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Glycine; Kynurenic Acid; Molecular Structure; Quinolines; Rats; Receptors, N-Methyl-D-Aspartate; Strychnine | 1990 |
Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists.
Topics: Animals; Blood Proteins; Blood-Brain Barrier; Brain; Excitatory Amino Acid Antagonists; Male; Mice; Protein Binding; Rats; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate | 1997 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Specificity and potency of N-methyl-D-aspartate glycine site antagonists and of mephenesin on the rat spinal cord in vitro.
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Binding Sites; Glycine; Ibotenic Acid; Indoles; Kynurenic Acid; Mephenesin; N-Methylaspartate; Pyrrolidinones; Quinoxalines; Rats; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1992 |
Effects of felbamate, kynurenic acid derivatives and NMDA antagonists on in vitro kainate-induced epileptiform activity.
Topics: Animals; Anticonvulsants; Excitatory Amino Acid Antagonists; Felbamate; Hippocampus; In Vitro Techniques; Kainic Acid; Kynurenic Acid; Male; N-Methylaspartate; Neuroprotective Agents; Phenylcarbamates; Propylene Glycols; Rats; Rats, Wistar | 1996 |
In vitro and in vivo antagonistic activities of SM-31900 for the NMDA receptor glycine-binding site.
Topics: Aminoquinolines; Animals; Binding, Competitive; Brain; Cells, Cultured; Dizocilpine Maleate; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Fetus; Glutamic Acid; Indoles; Kynurenic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Radioligand Assay; Rats; Rats, Sprague-Dawley; Rats, Wistar; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Seizures | 2002 |
The neuroprotector kynurenic acid increases neuronal cell survival through neprilysin induction.
Topics: Animals; Cell Survival; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Induction; Gene Expression; Humans; Kynurenic Acid; Mice; Neprilysin; Neurons; Neuroprotective Agents; Primary Cell Culture; Receptors, N-Methyl-D-Aspartate; Thiorphan | 2013 |