Compounds > 5,6-methylenedioxy-2-aminoindane
Page last updated: 2024-09-03

5,6-methylenedioxy-2-aminoindane and n-methyl-3,4-methylenedioxyamphetamine

5,6-methylenedioxy-2-aminoindane has been researched along with n-methyl-3,4-methylenedioxyamphetamine in 7 studies

Compound Research Comparison

Studies
(5,6-methylenedioxy-2-aminoindane)		Trials
(5,6-methylenedioxy-2-aminoindane)		Recent Studies (post-2010)
(5,6-methylenedioxy-2-aminoindane)		Studies
(n-methyl-3,4-methylenedioxyamphetamine)		Trials
(n-methyl-3,4-methylenedioxyamphetamine)		Recent Studies (post-2010) (n-methyl-3,4-methylenedioxyamphetamine)
170124,2762111,392

Protein Interaction Comparison

ProteinTaxonomy5,6-methylenedioxy-2-aminoindane (IC50)n-methyl-3,4-methylenedioxyamphetamine (IC50)
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.9351
Sodium-dependent serotonin transporterHomo sapiens (human)1.1761
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)1.06
Sodium-dependent dopamine transporter Homo sapiens (human)1.7609

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brewster, WK; Johnson, MP; Nichols, DE; Oberlender, R; Riggs, RM1
Huang, XM; Johnson, MP; Nichols, DE1
Nichols, DE; Oberlender, R1
Johnson, MP; Nichols, DE; Schmidt, CJ; Sprague, JE1
Karila, L; Reynaud, M1
Dolan, SB; Forster, MJ; Gatch, MB1
Beck, A; Flockerzi, V; Maurer, HH; Meyer, MR; Richter, LHJ1

Reviews

1 review(s) available for 5,6-methylenedioxy-2-aminoindane and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
GHB and synthetic cathinones: clinical effects and potential consequences.
    Drug testing and analysis, 2011, Volume: 3, Issue:9

    Topics: Alkaloids; Animals; Designer Drugs; Humans; Illicit Drugs; Indans; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Sodium Oxybate; Substance-Related Disorders

2011

Other Studies

6 other study(ies) available for 5,6-methylenedioxy-2-aminoindane and n-methyl-3,4-methylenedioxyamphetamine

ArticleYear
Nonneurotoxic tetralin and indan analogues of 3,4-(methylenedioxy)amphetamine (MDA).
    Journal of medicinal chemistry, 1990, Volume: 33, Issue:2

    Topics: 3,4-Methylenedioxyamphetamine; Amphetamines; Animals; Behavior, Animal; Catecholamines; Cerebral Cortex; Hippocampus; Indans; Lysergic Acid Diethylamide; N-Methyl-3,4-methylenedioxyamphetamine; Paroxetine; Piperidines; Psychotropic Drugs; Rats; Serotonin; Structure-Activity Relationship; Tetrahydronaphthalenes

1990
Serotonin neurotoxicity in rats after combined treatment with a dopaminergic agent followed by a nonneurotoxic 3,4-methylenedioxymethamphetamine (MDMA) analogue.
    Pharmacology, biochemistry, and behavior, 1991, Volume: 40, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Amphetamine; Animals; Brain; Dopamine; Dopamine Agents; Homovanillic Acid; Hydroxyindoleacetic Acid; Indans; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Serotonin

1991
(+)-N-methyl-1-(1,3-benzodioxol-5-yl)-2-butanamine as a discriminative stimulus in studies of 3,4-methylenedioxy-methamphetamine-like behavioral activity.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 255, Issue:3

    Topics: 3,4-Methylenedioxyamphetamine; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Hallucinogens; Indans; Learning; Male; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Inbred Strains; Stereoisomerism

1990
Studies on the mechanism of p-chloroamphetamine neurotoxicity.
    Biochemical pharmacology, 1996, Oct-25, Volume: 52, Issue:8

    Topics: Animals; Brain; Clorgyline; Dopamine; Fever; Hydroxyindoleacetic Acid; Indans; Male; Monoamine Oxidase Inhibitors; N-Methyl-3,4-methylenedioxyamphetamine; Neuroprotective Agents; Neurotoxins; p-Chloroamphetamine; Paroxetine; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Selegiline; Serotonin; Serotonin Agents

1996
Locomotor, discriminative stimulus, and place conditioning effects of MDAI in rodents.
    Behavioural pharmacology, 2016, Volume: 27, Issue:6

    Topics: Animals; Central Nervous System Stimulants; Cocaine; Conditioning, Psychological; Discrimination Learning; DOM 2,5-Dimethoxy-4-Methylamphetamine; Dose-Response Relationship, Drug; Hallucinogens; Indans; Locomotion; Male; Methamphetamine; Mice; N-Methyl-3,4-methylenedioxyamphetamine; Rats; Rats, Sprague-Dawley

2016
Cytotoxicity of new psychoactive substances and other drugs of abuse studied in human HepG2 cells using an adopted high content screening assay.
    Toxicology letters, 2019, Volume: 301

    Topics: Acetaminophen; Alkaloids; Biological Assay; Chromatography, Liquid; Fluorescent Dyes; Fluvastatin; Hep G2 Cells; Hepatocytes; Humans; Illicit Drugs; Indans; Indoles; Membrane Potential, Mitochondrial; Methamphetamine; N-Methyl-3,4-methylenedioxyamphetamine; Propranolol; Quinolines; Simvastatin; Tandem Mass Spectrometry; Toxicity Tests

2019