5,6-dimethylbenzimidazole has been researched along with vitamin b 12 in 46 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (21.74) | 18.7374 |
| 1990's | 12 (26.09) | 18.2507 |
| 2000's | 13 (28.26) | 29.6817 |
| 2010's | 11 (23.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heckmann, G; Hörig, JA; Renz, P | 1 |
| Hörig, J; Renz, P | 1 |
| Lingens, B; Renz, P; Schild, TA; Vogler, B | 1 |
| Munder, M; Renz, P; Vogler, B; Vogt, JR | 1 |
| Escalante-Semerena, JC; Johnson, MG | 1 |
| Renz, P; Vogt, JR | 1 |
| Hörig, JA; Renz, P | 1 |
| Heckmann, G; Lamm, L; Renz, P | 1 |
| Heckmann, G; Hörig, JA; Lamm, L; Renz, P | 1 |
| Renz, P; Ruoff, D; Schulze, B; Volger, B | 1 |
| Bisping, B; Keuth, S | 1 |
| Escalante-Semerena, JC; O'Toole, GA; Trzebiatowski, JR | 1 |
| Endres, B; Kurz, B; Marquart, J; Renz, P | 1 |
| Drennan, CL; Ludwig, ML; Matthews, RG | 1 |
| Keck, B; Munder, M; Renz, P | 1 |
| Gerfen, GJ; Lawrence, CC; Nitsche, R; Rétey, J; Robins, MJ; Samano, V; Stubbe, J | 1 |
| Ke, SC; Morokuma, K; Museav, DG; Torrent, M; Warncke, K | 1 |
| Escalante-Semerena, JC; Maggio-Hall, LA | 2 |
| Boss, GR; Magde, D; Pilz, RB; Sharma, VS | 1 |
| BALA, E; DUMITRESCU, Z; MARCUS, J | 1 |
| BURGUS, RC; HUFHAM, JB; PFIFFNER, JJ; SCOTT, WM | 1 |
| Dorweiler, JS; Finke, RG; Matthews, RG | 1 |
| BOXER, GE; RICKARDS, JC | 1 |
| COOPERMAN, JM; DRUCKER, R; TABENKIN, B | 1 |
| Bowen, RD; Fox, A | 1 |
| Anderson, PJ; Campbell, GR; Lloret, J; Mistry, K; Roth, JR; Taga, ME; Walker, GC | 1 |
| Warren, MJ | 1 |
| Escalante-Semerena, JC; Gray, MJ | 1 |
| Begley, TP; Ealick, SE | 1 |
| Howard-Jones, AR; Larsen, NA; Taga, ME; Walker, GC; Walsh, CT | 1 |
| Anderson, PJ; Britten, A; Carkeet, C; Hammock, BD; Kräutler, B; Lango, J; Roth, JR | 1 |
| Taga, ME; Walker, GC | 1 |
| Brasch, NE; Brown, KL; Hannibal, L; Hassanin, HA; Jacobsen, DW; Marques, HM | 1 |
| Macartney, DH; Macgillivray, BC; Wang, R | 1 |
| Brasch, NE; DeBeer, S; El-Shahat, MF; Hassanin, HA; Smith, CA | 1 |
| Männel-Croisé, C; Zelder, F | 1 |
| Im, J; Löffler, FE; Yan, J; Yang, Y | 1 |
| Fernandes, MA; Marques, HM; Perry, CB; Shin, N | 1 |
| Crofts, TS; Hazra, AB; Taga, ME; Tran, JL | 1 |
| Allen, RH; Alvarez-Cohen, L; Crofts, TS; Men, Y; Seth, EC; Taga, ME; Yi, S | 1 |
| Allen, RH; Brito, A; Chiquette, J; Girard, CL; Stabler, SP | 1 |
| Jiao, Y; Liu, S; Wang, P; Wang, Y; Zhang, Z | 1 |
| Begley, TP; Han, AW; Hazra, AB; Mehta, AP; Mok, KC; Osadchiy, V; Taga, ME | 1 |
| Bonacina, J; Font, G; Saavedra, L; Taranto, MP; Torres, AC; Vannini, V | 1 |
| Abdelwahed, SH; Begley, TP; Britt, RD; Gagnon, DM; Mehta, AP; Stich, TA | 1 |
1 review(s) available for 5,6-dimethylbenzimidazole and vitamin b 12
| Article | Year |
|---|---|
The reactivity of B12 cofactors: the proteins make a difference.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Amino Acid Sequence; Animals; Benzimidazoles; Cobamides; Escherichia coli; Histidine; Humans; Methylmalonyl-CoA Mutase; Methyltransferases; Models, Molecular; Molecular Sequence Data; Propionibacterium; Vitamin B 12 | 1996 |
1 trial(s) available for 5,6-dimethylbenzimidazole and vitamin b 12
| Article | Year |
|---|---|
Supplementing lactating dairy cows with a vitamin B12 precursor, 5,6-dimethylbenzimidazole, increases the apparent ruminal synthesis of vitamin B12.
Topics: Animals; Benzimidazoles; Cattle; Cobalt; Cross-Over Studies; Dietary Supplements; Female; Fermentation; Lactation; Milk; Omasum; Rumen; Vitamin B 12 | 2015 |
44 other study(ies) available for 5,6-dimethylbenzimidazole and vitamin b 12
| Article | Year |
|---|---|
[5-15N]Riboflavin as precursor in the biosynthesis of the 5,6-dimethylbenzimidazole moiety of vitamin B12. A study by 1H and 15N magnetic resonance spectroscopy.
Topics: Benzimidazoles; Magnetic Resonance Spectroscopy; Propionibacterium; Riboflavin; Vitamin B 12 | 1978 |
Biosynthesis of vitamin B12. Formation of free 5,6-dimethylbenzimidazole and alpha-ribazole from riboflavin by Propionibacterium freudenreichii.
Topics: Benzimidazoles; Propionibacterium; Riboflavin; Ribonucleosides; Vitamin B 12 | 1977 |
Biosynthesis of vitamin B12. Transformation of riboflavin 2H-labeled in the 1'R position of 1'S position into 5,6-dimethylbenzimidazole.
Topics: Benzimidazoles; Flavin Mononucleotide; Hydrogen; Magnetic Resonance Spectroscopy; Mass Spectrometry; Propionibacterium; Riboflavin; Stereoisomerism; Vitamin B 12 | 1992 |
Biosynthesis of vitamin B12 in anaerobic bacteria. Experiments with Eubacterium limosum on the incorporation of D-[1-13C]erythrose and [13C]formate into the 5,6-dimethylbenzimidazole moiety.
Topics: Benzimidazoles; Carbon Isotopes; Eubacterium; Formates; Magnetic Resonance Spectroscopy; Methylation; Tetroses; Vitamin B 12 | 1992 |
Identification of 5,6-dimethylbenzimidazole as the Co alpha ligand of the cobamide synthesized by Salmonella typhimurium. Nutritional characterization of mutants defective in biosynthesis of the imidazole ring.
Topics: Benzimidazoles; Chromatography, High Pressure Liquid; Cobamides; Imidazoles; Magnetic Resonance Spectroscopy; Mutation; Salmonella typhimurium; Spectrometry, Mass, Fast Atom Bombardment; Spectrophotometry, Ultraviolet; Vitamin B 12 | 1992 |
Biosynthesis of vitamin B-12 in anaerobic bacteria. Experiments with Eubacterium limosum on the origin of the amide groups of the corrin ring and of N-3 of the 5,6-dimethylbenzimidazole part.
Topics: Amides; Anaerobiosis; Benzimidazoles; Corrinoids; Eubacterium; Fermentation; Hydrolysis; Magnetic Resonance Spectroscopy; Methylation; Vitamin B 12 | 1988 |
Biosynthesis of vitamin B12. Some properties of the 5,6-dimethylbenzimidazole-forming system of Propionibacterium freudenreichii and Propionibacterium shermanii.
Topics: Benzimidazoles; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Niacinamide; Nicotinic Acids; Propionibacterium; Riboflavin; Vitamin B 12 | 1980 |
Biosynthesis of vitamin B12 in anaerobic bacteria. Mode of incorporation of glycine into the 5,6-dimethylbenzimidazole moiety in Eubacterium limosum.
Topics: Benzimidazoles; Eubacterium; Glycine; Hydrolysis; Vitamin B 12 | 1982 |
Biosynthesis of vitamin B12. Experiments with the anaerobe Eubacterium limosum and some labelled substrates.
Topics: Anaerobiosis; Benzimidazoles; Carbon Isotopes; Carbon Radioisotopes; Eubacterium; Glycine; Magnetic Resonance Spectroscopy; Methionine; Vitamin B 12 | 1980 |
Mode of transformation of [1-15N]5-hydroxybenzimidazole and [1-15N]5-hydroxy-6-methylbenzimidazole into the 5,6-dimethylbenzimidazole moiety of vitamin B12.
Topics: Benzimidazoles; Cobamides; Eubacterium; Magnetic Resonance Spectroscopy; Vitamin B 12 | 1994 |
Vitamin B12 production by Citrobacter freundii or Klebsiella pneumoniae during tempeh fermentation and proof of enterotoxin absence by PCR.
Topics: Base Sequence; Benzimidazoles; Citrobacter freundii; Cobalt; DNA; Enterotoxins; Fermentation; Food Microbiology; Glycine max; Klebsiella pneumoniae; Molecular Sequence Data; Polymerase Chain Reaction; Temperature; Vitamin B 12 | 1994 |
The cobT gene of Salmonella typhimurium encodes the NaMN: 5,6-dimethylbenzimidazole phosphoribosyltransferase responsible for the synthesis of N1-(5-phospho-alpha-D-ribosyl)-5,6-dimethylbenzimidazole, an intermediate in the synthesis of the nucleotide loo
Topics: Amino Acid Sequence; Benzimidazoles; Chromosome Mapping; Genes, Bacterial; Molecular Sequence Data; Multienzyme Complexes; Mutation; Nucleotidyltransferases; Pentosyltransferases; Ribonucleotides; Salmonella typhimurium; Sequence Homology, Amino Acid; Vitamin B 12 | 1994 |
Biosynthesis of vitamin B12 in anaerobic bacteria. Transformation of 5-hydroxybenzimidazole and 5-hydroxy-6-methylbenzimidazole into 5,6-dimethylbenzimidazole in Eubacterium limosum.
Topics: Benzimidazoles; Biotransformation; Eubacterium; Vitamin B 12 | 1993 |
Biosynthesis of cobalamin in Salmonella typhimurium: transformation of riboflavin into the 5,6-dimethylbenzimidazole moiety.
Topics: Benzimidazoles; Riboflavin; Salmonella typhimurium; Vitamin B 12 | 1998 |
Binding of Cob(II)alamin to the adenosylcobalamin-dependent ribonucleotide reductase from Lactobacillus leichmannii. Identification of dimethylbenzimidazole as the axial ligand.
Topics: Benzimidazoles; Catalysis; Cobamides; Deoxycytosine Nucleotides; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Lactobacillus; Ligands; Protein Binding; Ribonucleotide Reductases; Vitamin B 12 | 1999 |
Identification of dimethylbenzimidazole axial coordination and characterization of (14)N superhyperfine and nuclear quadrupole coupling in Cob(II)alamin bound to ethanolamine deaminase in a catalytically-engaged substrate radical-Cobalt(II) biradical stat
Topics: Benzimidazoles; Catalysis; Cobalt; Electron Spin Resonance Spectroscopy; Ethanolamine Ammonia-Lyase; Nitrogen Isotopes; Substrate Specificity; Vitamin B 12 | 1999 |
In vitro synthesis of the nucleotide loop of cobalamin by Salmonella typhimurium enzymes.
Topics: Bacterial Proteins; Benzimidazoles; Chromatography, High Pressure Liquid; Cobamides; Mass Spectrometry; Models, Chemical; Multienzyme Complexes; Nitrogenous Group Transferases; Nucleotides; Nucleotidyltransferases; Pentosyltransferases; Plasmids; Salmonella typhimurium; Time Factors; Transaminases; Vitamin B 12 | 1999 |
Alpha-5,6-dimethylbenzimidazole adenine dinucleotide (alpha-DAD), a putative new intermediate of coenzyme B12 biosynthesis in Salmonella typhimurium.
Topics: Adenine Nucleotides; ADP Ribose Transferases; Benzimidazoles; Cobamides; Kinetics; Multienzyme Complexes; NAD; Nucleotidyltransferases; Pentosyltransferases; Ribonucleotides; Salmonella typhimurium; Substrate Specificity; Vitamin B 12 | 2003 |
Reactions of nitric oxide with vitamin B12 and its precursor, cobinamide.
Topics: Benzimidazoles; Cobamides; Hydrogen-Ion Concentration; Kinetics; Light; Models, Chemical; Nitric Oxide; Nitrogen; Protein Binding; Time Factors; Vitamin B 12 | 2003 |
[5,6-Dimethylbenzimidazole, synthetic first stage for the production of vitamin B 12 by microbiological means].
Topics: Benzimidazoles; Vitamin B 12 | 1961 |
MICROBIAL DEGRADATION OF CORRINOIDS. 3. PIGMENTS DERIVED FROM VITAMIN B12 BY PSEUDOMONAS RUBESCENS.
Topics: Benzimidazoles; Chemical Phenomena; Chemistry; Chromatography; Coenzymes; Corrinoids; Cyanides; Electrophoresis; Enterobacter aerogenes; Lactobacillus; Metabolism; Pigments, Biological; Pseudomonas; Research; Spectrum Analysis; Vitamin B 12 | 1964 |
Cobalamin-dependent methionine synthase: probing the role of the axial base in catalysis of methyl transfer between methyltetrahydrofolate and exogenous cob(I)alamin or cob(I)inamide.
Topics: 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Benzimidazoles; Catalysis; Cations; Cobamides; Models, Chemical; Pyridines; Quaternary Ammonium Compounds; Solutions; Spectrophotometry, Ultraviolet; Tetrahydrofolates; Thermodynamics; Vitamin B 12 | 2003 |
Chemical determination of vitamin B12; I. Determination of 5,6-dimethylbenzimidazole by colorimetric and fluorometric methods.
Topics: Benzimidazoles; Corrinoids; Fluorometry; Vitamin B 12 | 1950 |
Growth response and vitamin B12 tissue levels in vitamin B12-deficient rats and chicks fed riboflavin, 5,6-dimethylbenzimidazole and related compounds.
Topics: Animals; Benzimidazoles; Chickens; Rats; Riboflavin; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex | 1952 |
Differentiation of ionised benzimidazole from its isomeric alpha-distonic ion by collision-induced dissociation and neutralisation-reionisation mass spectrometry.
Topics: Benzimidazoles; Cations; Spectrometry, Mass, Electrospray Ionization; Thermodynamics; Vitamin B 12; Vitamin B Complex | 2005 |
Sinorhizobium meliloti bluB is necessary for production of 5,6-dimethylbenzimidazole, the lower ligand of B12.
Topics: Benzimidazoles; Genes, Bacterial; Ligands; Medicago sativa; Molecular Sequence Data; Sinorhizobium meliloti; Symbiosis; Vitamin B 12 | 2006 |
Finding the final pieces of the vitamin B12 biosynthetic jigsaw.
Topics: Benzimidazoles; Flavin Mononucleotide; Vitamin B 12 | 2006 |
Single-enzyme conversion of FMNH2 to 5,6-dimethylbenzimidazole, the lower ligand of B12.
Topics: Bacterial Proteins; Benzimidazoles; Catalysis; Chlorophyll; Flavin Mononucleotide; Heterotrophic Processes; Ligands; Mutant Proteins; Oxygen; Protoporphyrins; Rhodospirillum rubrum; Sequence Homology; Vitamin B 12 | 2007 |
Biochemistry: molecular cannibalism.
Topics: Benzimidazoles; Binding Sites; Flavin Mononucleotide; FMN Reductase; Sinorhizobium meliloti; Vitamin B 12 | 2007 |
BluB cannibalizes flavin to form the lower ligand of vitamin B12.
Topics: Benzimidazoles; Binding Sites; Catalysis; Flavin Mononucleotide; FMN Reductase; Genes, Bacterial; Ligands; Models, Molecular; Mutation; Oxidation-Reduction; Oxygen; Protein Conformation; Sinorhizobium meliloti; Vitamin B 12 | 2007 |
One pathway can incorporate either adenine or dimethylbenzimidazole as an alpha-axial ligand of B12 cofactors in Salmonella enterica.
Topics: Adenine; Adenine Phosphoribosyltransferase; Aerobiosis; Anaerobiosis; Bacterial Proteins; Benzimidazoles; Chromatography, High Pressure Liquid; Cobamides; Corrinoids; Ethanolamine; Gene Expression Regulation, Bacterial; Ligands; Mass Spectrometry; Models, Biological; Molecular Structure; Mutagenesis; Mutation; N-Glycosyl Hydrolases; Phenotype; Polymerase Chain Reaction; Salmonella enterica; Vitamin B 12 | 2008 |
Pseudo-B12 joins the cofactor family.
Topics: Adenine; Bacterial Proteins; Benzimidazoles; Corrinoids; Models, Biological; Molecular Structure; Salmonella enterica; Vitamin B 12 | 2008 |
NMR spectroscopy and molecular modelling studies of nitrosylcobalamin: further evidence that the deprotonated, base-off form is important for nitrosylcobalamin in solution.
Topics: Benzimidazoles; Crystallography, X-Ray; Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Conformation; Nitrogen; Nitroso Compounds; Protons; Solutions; Spectrophotometry, Ultraviolet; Temperature; Thermodynamics; Vitamin B 12 | 2009 |
Stabilization of the base-off forms of vitamin B(12) and coenzyme B(12) by encapsulation of the alpha-axial 5,6-dimethylbenzimidazole ligand with cucurbit[7]uril.
Topics: Benzimidazoles; Bridged-Ring Compounds; Cobamides; Hydrogen-Ion Concentration; Imidazoles; Kinetics; Magnetic Resonance Spectroscopy; Photolysis; Spectrophotometry, Ultraviolet; Titrimetry; Vitamin B 12 | 2009 |
Redetermination of the X-ray structure of nitroxylcobalamin: base-on nitroxylcobalamin exhibits a remarkably long Co-N(dimethylbenzimidazole) bond distance.
Topics: Benzimidazoles; Cobalt; Nitrogen; Nitrogen Oxides; Organometallic Compounds; Scattering, Small Angle; Vitamin B 12; X-Ray Diffraction | 2010 |
Immobilised vitamin B12 as a biomimetic model for base-off/histidine-on coordination.
Topics: Benzimidazoles; Biomimetic Materials; Histidine; Hydrogen-Ion Concentration; Surface Properties; Vitamin B 12 | 2011 |
Guided cobalamin biosynthesis supports Dehalococcoides mccartyi reductive dechlorination activity.
Topics: Bacteriological Techniques; Benzimidazoles; Biodegradation, Environmental; Chloroflexi; Chromatography, High Pressure Liquid; Coculture Techniques; Culture Media; Dichloroethylenes; Halogenation; Oxidation-Reduction; Trichloroethylene; Vitamin B 12 | 2013 |
Phenylvinylcobalamin: an alkenylcobalamin featuring a ligand with a large trans influence.
Topics: Benzimidazoles; Crystallography, X-Ray; Isomerism; Ligands; Models, Molecular; Thermodynamics; Vinyl Compounds; Vitamin B 12 | 2013 |
Analysis of substrate specificity in CobT homologs reveals widespread preference for DMB, the lower axial ligand of vitamin B(12).
Topics: Bacteria; Benzimidazoles; Binding, Competitive; Cobamides; Ligands; Multienzyme Complexes; Nucleotidyltransferases; Pentosyltransferases; Reproducibility of Results; Ribonucleosides; Sinorhizobium meliloti; Structural Homology, Protein; Substrate Specificity; Vitamin B 12 | 2013 |
Identification of specific corrinoids reveals corrinoid modification in dechlorinating microbial communities.
Topics: Benzimidazoles; Biodegradation, Environmental; Chloroflexi; Chromatography, Liquid; Cresols; Hydrocarbons, Chlorinated; Ligands; Microbial Consortia; Phylogeny; Tandem Mass Spectrometry; Trichloroethylene; Veillonellaceae; Vitamin B 12 | 2015 |
Improved propionic acid and 5,6-dimethylbenzimidazole control strategy for vitamin B12 fermentation by Propionibacterium freudenreichii.
Topics: Benzimidazoles; Bioreactors; Fermentation; Propionates; Propionibacterium; Vitamin B 12 | 2015 |
Anaerobic biosynthesis of the lower ligand of vitamin B12.
Topics: Anaerobiosis; Archaea; Bacterial Proteins; Benzimidazoles; Corrinoids; DNA, Recombinant; Escherichia coli; Eubacterium; Genes, Archaeal; Genes, Bacterial; Geobacter; Metabolic Networks and Pathways; Molecular Sequence Data; Molecular Structure; Moorella; Phylogeny; Recombinant Proteins; Riboswitch; Salmonella typhimurium; Sequence Alignment; Sequence Homology, Nucleic Acid; Vitamin B 12 | 2015 |
Cobalamin production by Lactobacillus coryniformis: biochemical identification of the synthetized corrinoid and genomic analysis of the biosynthetic cluster.
Topics: Adenine; Anaerobiosis; Bacterial Proteins; Base Sequence; Benzimidazoles; Chromatography, High Pressure Liquid; Cobamides; Genes, Bacterial; Lactobacillus; Mass Spectrometry; Multigene Family; Open Reading Frames; Salmonella enterica; Salmonella typhimurium; Sequence Analysis, Protein; Silage; Vitamin B 12 | 2016 |
An Aminoimidazole Radical Intermediate in the Anaerobic Biosynthesis of the 5,6-Dimethylbenzimidazole Ligand to Vitamin B12.
Topics: Anaerobiosis; Bacterial Proteins; Benzimidazoles; Biosynthetic Pathways; Desulfuromonas; Electron Spin Resonance Spectroscopy; S-Adenosylmethionine; Vitamin B 12 | 2018 |