5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine has been researched along with sch 28080 in 1 studies
*Sch 28080: not related structurally to other known anti-ulcer agents; inhibits histamine-stimulated gastric secretion; prevents gastric lesions induced by aspirin, indomethacin & ethanol [MeSH]
*Sch 28080: not related structurally to other known anti-ulcer agents; inhibits histamine-stimulated gastric secretion; prevents gastric lesions induced by aspirin, indomethacin & ethanol [MeSH]
| Studies (5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine) | Trials (5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine) | Recent Studies (post-2010) (5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine) | Studies (sch 28080) | Trials (sch 28080) | Recent Studies (post-2010) (sch 28080) |
|---|---|---|---|---|---|
| 5 | 0 | 5 | 217 | 0 | 20 |
| Protein | Taxonomy | 5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine (IC50) | sch 28080 (IC50) |
|---|---|---|---|
| Cytochrome P450 1A2 | Homo sapiens (human) | 2 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 9 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abe, K; Gerle, C; Hayashida, K; Khandelia, H; Madapally, HV; Morita, M; Oshima, A; Shigematsu, H; Tanaka, S; Yamagishi, T | 1 |
1 other study(ies) available for 5,6-dimethyl-2-(4-fluorophenylamino)-4-(1-methyl-1,2,3,4-tetrahydroisoquinolin-2-yl)pyrimidine and sch 28080
| Article | Year |
|---|---|
Structural Basis for Binding of Potassium-Competitive Acid Blockers to the Gastric Proton Pump.
Topics: Gastric Acid; Potassium; Proton Pump Inhibitors; Proton Pumps; Stomach | 2022 |