5,6-dihydroxyindole has been researched along with 5,6-dihydroxy-2-indolylcarboxylic acid in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (12.50) | 18.7374 |
| 1990's | 20 (50.00) | 18.2507 |
| 2000's | 9 (22.50) | 29.6817 |
| 2010's | 6 (15.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Prota, G | 1 |
| Orlow, SJ; Osber, MP; Pawelek, JM | 1 |
| Aroca, P; García-Borrón, JC; Lozano, JA; Salinas, C; Solano, F | 1 |
| d'Ischia, M; Napolitano, A; Prota, G | 1 |
| Pawelek, JM | 1 |
| Chacon, JN; Chedekel, MR; Lambert, C; Land, EJ; Riley, PA; Thompson, A; Truscott, TG | 1 |
| Chedekel, MR; Koch, WH | 1 |
| Ito, S | 1 |
| King, RA; Leonard, LJ; Townsend, D | 1 |
| Ito, S; Wakamatsu, K | 1 |
| Brewington, T; García-Borrón, JC; Hearing, VJ; Imokawa, G; Jiménez-Cervantes, C; Kobayashi, T; Solano, F; Urabe, K; Winder, A | 1 |
| Brewington, T; Hearing, VJ; Imokawa, G; Kobayashi, T; Potterf, B; Tsukamoto, K; Urabe, K; Winder, A | 1 |
| Aroca, P; Hearing, VJ; Mascagna, D; Palumbo, A; Prota, G; Tsukamoto, K; Urabe, K | 1 |
| Mishima, Y; Wilczek, A | 1 |
| Pavel, S | 1 |
| Kondoh, H; Mishima, Y; Wilczek, A | 1 |
| Aman, P; Bucala, R; Jacobsson, L; Metz, CN; Odh, G; Rorsman, H; Rosengren, E | 1 |
| Nappi, AJ; Vass, E | 1 |
| Ishiguro, I; Ito, S; Ozeki, H; Wakamatsu, K | 1 |
| d'Ischia, M; Memoli, S; Misuraca, G; Napolitano, A; Palumbo, A; Prota, G | 1 |
| Fujinaga, M; Kuriyama, T; Nakagawa, A; Nishihira, J; Sakai, M; Sugimoto, H; Suzuki, M; Tanaka, I | 1 |
| d'Ischia, M; Novellino, L; Prota, G | 1 |
| Blarzino, C; Coccia, R; De Marco, C; Foppoli, C; Mosca, L; Rosei, MA | 1 |
| Napolitano, A; Novellino, L; Prota, G | 2 |
| Hearing, V; Matsunaga, J; Santis, C; Sinha, D; Solano, F; Wistow, G | 1 |
| Allegri, G; Bertazzo, A; Costa, CV; Favretto, D; Traldi, P; Vogliardi, S | 1 |
| Alaluf, S; Atkins, D; Barrett, K; Carter, N; Heath, A; Kolb, R; Mahalingam, H; Smit, N | 1 |
| Borges, CR; Roberts, JC; Rollins, DE; Wilkins, DG | 1 |
| Hatao, M; Maeda, K | 1 |
| Adachi, K; Hirata, T; Ito, S; Kokubo, T; Miyamoto, N; Nishioka, T; Wakamatsu, K | 1 |
| Charkoudian, LK; Franz, KJ | 1 |
| d'Ischia, M; Edge, R; Land, EJ; Napolitano, A; Navaratnam, S; Panzella, L; Pezzella, A; Ramsden, CA; Riley, PA | 1 |
| Carton, Y; Kohler, LJ; Mastore, M; Nappi, AJ | 1 |
| Peles, DN; Simon, JD | 1 |
| Commo, S; Ito, S; Suzuki, N; Takebayashi, S; Wakamatsu, K | 1 |
| Kasai, H; Kishida, R; Saputro, AG; Ushijima, Y | 1 |
| Barek, H; Ito, S; Sugumaran, M; Wakamatsu, K | 1 |
| Araujo-Andrade, C; Galván, I; Loza-Alvarez, P; Marro, M; Wakamatsu, K | 1 |
| Ito, S; Itou, T; Wakamatsu, K | 1 |
2 review(s) available for 5,6-dihydroxyindole and 5,6-dihydroxy-2-indolylcarboxylic acid
| Article | Year |
|---|---|
After dopachrome?
Topics: Animals; Cell Fractionation; Enzyme Activation; Indolequinones; Indoles; Isomerases; Melanins; Melanocytes; Melanoma; Pigmentation; Quinones; Tumor Cells, Cultured | 1991 |
Dynamics of melanogenesis intermediates.
Topics: Biological Transport; Catechol O-Methyltransferase Inhibitors; Humans; Indoles; Melanins; Melanocytes; Monophenol Monooxygenase; Tyrosine | 1993 |
38 other study(ies) available for 5,6-dihydroxyindole and 5,6-dihydroxy-2-indolylcarboxylic acid
| Article | Year |
|---|---|
The role of peroxidase in melanogenesis revisited.
Topics: Benzoquinones; Dihydroxyphenylalanine; Indoles; Melanins; Molecular Structure; Monophenol Monooxygenase; Oxidation-Reduction; Peroxidase; Plant Proteins; Tyrosine | 1992 |
Synthesis and characterization of melanins from dihydroxyindole-2-carboxylic acid and dihydroxyindole.
Topics: Animals; Humans; Indoles; Intramolecular Oxidoreductases; Isomerases; Melanins; Mice; Polymers; Solubility; Tumor Cells, Cultured | 1992 |
Regulation of the final phase of mammalian melanogenesis. The role of dopachrome tautomerase and the ratio between 5,6-dihydroxyindole-2-carboxylic acid and 5,6-dihydroxyindole.
Topics: Animals; Chromatography, Gel; Indoles; Intramolecular Oxidoreductases; Isomerases; Kinetics; Melanins; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred Strains; Models, Biological; Monophenol Monooxygenase | 1992 |
Peroxidase as an alternative to tyrosinase in the oxidative polymerization of 5,6-dihydroxyindoles to melanin(s).
Topics: Chromatography, High Pressure Liquid; Hydrogen Peroxide; Indoles; Kinetics; Macromolecular Substances; Melanins; Monophenol Monooxygenase; Oxidation-Reduction; Peroxidase; Spectrophotometry | 1991 |
A pulse radiolysis investigation of the oxidation of indolic melanin precursors: evidence for indolequinones and subsequent intermediates.
Topics: Indoles; Kinetics; Melanins; Molecular Structure; Oxidation-Reduction; Quinones; Spectrophotometry; Structure-Activity Relationship; Thiocyanates | 1989 |
Photogeneration of free radicals from eumelanogenic intermediates and metabolites.
Topics: Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Free Radicals; Indoles; Photolysis; Spectrophotometry; Ultraviolet Rays | 1987 |
Reexamination of the structure of eumelanin.
Topics: Animals; Carbon; Dihydroxyphenylalanine; Hydrochloric Acid; Indoles; Manganese; Manganese Compounds; Melanins; Melanocytes; Mice; Mollusca; Monophenol Monooxygenase; Nitrogen; Oxidation-Reduction; Oxides | 1986 |
Function of dopachrome oxidoreductase and metal ions in dopachrome conversion in the eumelanin pathway.
Topics: Animals; Catechol Oxidase; Hot Temperature; In Vitro Techniques; Indolequinones; Indoles; Intramolecular Oxidoreductases; Melanins; Melanocytes; Melanoma, Experimental; Metals; Mice; Quinones | 1988 |
Preparation of eumelanin-related metabolites 5,6-dihydroxyindole, 5,6-dihydroxyindole-2-carboxylic acid, and their O-methyl derivatives.
Topics: Alkalies; Decarboxylation; Hot Temperature; Hydrogen-Ion Concentration; Hydrolysis; Indoles; Melanins; Methylation | 1988 |
Tyrosinase related protein 1 (TRP1) functions as a DHICA oxidase in melanin biosynthesis.
Topics: Animals; Cell-Free System; Chromatography, Affinity; Indoles; Melanins; Melanocytes; Melanoma; Membrane Glycoproteins; Mice; Monophenol Monooxygenase; Oxidation-Reduction; Oxidoreductases; Proteins; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1994 |
DHICA oxidase activity of TRP1 and interactions with other melanogenic enzymes.
Topics: Animals; Catalysis; Enzyme Stability; Fibroblasts; Indolequinones; Indoles; Melanins; Melanoma, Experimental; Membrane Glycoproteins; Mice; Monophenol Monooxygenase; Oxidoreductases; Pigmentation; Proteins; Quinones; Transfection | 1994 |
The inherent cytotoxicity of melanin precursors: a revision.
Topics: 3T3 Cells; Animals; Cell Division; Cell Survival; Dihydroxyphenylalanine; Hydrogen Peroxide; Indoles; Melanins; Mice; Microscopy, Phase-Contrast; Oxidation-Reduction; Protein Precursors; Tumor Cells, Cultured | 1994 |
Regulatory factors for polymerization of melanin monomers within coated vesicles and premelanosomes in melanoma cells.
Topics: Animals; Chromatography, Affinity; Chromatography, High Pressure Liquid; Coated Pits, Cell-Membrane; Cricetinae; Indolequinones; Indoles; Kinetics; Melanins; Melanocytes; Melanoma, Amelanotic; Melanoma, Experimental; Mesocricetus; Monophenol Monooxygenase; Organelles; Quinones | 1993 |
Composition of mammalian eumelanins: analyses of DHICA-derived units in pigments from hair and melanoma cells.
Topics: Animals; Asian People; Cricetinae; Hair; Hair Color; Humans; Indoles; Melanins; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Pigments, Biological; Polymers; Spectrophotometry; Tumor Cells, Cultured; White People | 1996 |
The immunoregulatory mediator macrophage migration inhibitory factor (MIF) catalyzes a tautomerization reaction.
Topics: Amino Acid Sequence; Animals; Cattle; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Indolequinones; Indoles; Lens, Crystalline; Macrophage Migration-Inhibitory Factors; Molecular Sequence Data; Molecular Structure; Quinones; Recombinant Proteins; Sequence Alignment; Sequence Analysis | 1996 |
Hydrogen peroxide generation associated with the oxidations of the eumelanin precursors 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid.
Topics: Catalase; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hydrogen Peroxide; Indoles; Iron; Kinetics; Melanins; Monophenol Monooxygenase; Oxidation-Reduction; Peroxidase; Salicylates | 1996 |
Chemical characterization of eumelanins with special emphasis on 5,6-dihydroxyindole-2-carboxylic acid content and molecular size.
Topics: Animals; Dihydroxyphenylalanine; Humans; Indoles; Melanins; Mice; Molecular Weight; Polymers; Pyrroles; Quaternary Ammonium Compounds; Solvents; Spectrophotometry; Tyrosine | 1997 |
Diffusible melanin-related metabolites are potent inhibitors of lipid peroxidation.
Topics: Animals; Cerebral Cortex; Cysteinyldopa; Edetic Acid; In Vitro Techniques; Indoles; Linoleic Acid; Linoleic Acids; Lipid Peroxidation; Male; Melanins; Protein Precursors; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances | 1997 |
Molecular cloning of human D-dopachrome tautomerase cDNA: N-terminal proline is essential for enzyme activation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; Enzyme Activation; Gene Expression Regulation; Humans; Indolequinones; Indoles; Intramolecular Oxidoreductases; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Proline; Quinones; Rats; RNA, Messenger; Sequence Alignment; Sequence Analysis, DNA | 1998 |
Nitric oxide-induced oxidation of 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid under aerobic conditions: non-enzymatic route to melanin pigments of potential relevance to skin (photo)protection.
Topics: Aerobiosis; Animals; Humans; In Vitro Techniques; Indoles; Melanins; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Skin; Skin Pigmentation; Ultraviolet Rays; Vitamin E | 1998 |
Lipoxygenase/H2O2-catalyzed oxidation of dihdroxyindoles: synthesis of melanin pigments and study of their antioxidant properties.
Topics: Antioxidants; Catalysis; Chromatography, High Pressure Liquid; Free Radicals; Hydrogen Peroxide; Indoles; Kinetics; Lipoxygenase; Melanins; Oxidation-Reduction | 1999 |
5,6-Dihydroxyindoles in the fenton reaction: a model study of the role of melanin precursors in oxidative stress and hyperpigmentary processes.
Topics: Carbon Dioxide; Chelating Agents; Deoxyribose; Edetic Acid; Hydrogen Peroxide; Hydroxyl Radical; Hyperpigmentation; Indoles; Iron; Melanins; Models, Biological; Oxidative Stress; Pigments, Biological; Proline | 1999 |
Macrophage migration inhibitory factor (MIF)--its role in catecholamine metabolism.
Topics: Animals; Brain; Catalysis; Catecholamines; Dopamine; Indoles; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Melanins; Mice; Nerve Tissue Proteins; Norepinephrine; Recombinant Fusion Proteins | 1999 |
Isolation and characterization of mammalian eumelanins from hair and irides.
Topics: Animals; Carbon Dioxide; Cattle; Deoxyribose; Europe; Ferricyanides; Hair; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Indoles; Iris; Melanins; Models, Molecular; Oxidation-Reduction; Proteins; Pyrroles; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Ultraviolet | 2000 |
Melanogenesis by tyrosinase action on 3,4-dihydroxyphenylalanine (DOPA) in the presence of polyethylene glycol: a matrix-assisted laser desorption/ionization mass spectrometric investigation.
Topics: Agaricales; Dihydroxyphenylalanine; Indoles; Kinetics; Molecular Structure; Monophenol Monooxygenase; Polyethylene Glycols; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | 2001 |
Variation in melanin content and composition in type V and VI photoexposed and photoprotected human skin: the dominant role of DHI.
Topics: Biopsy; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Epidermal Cells; Epidermis; Humans; Indoles; Light; Melanins; Melanosomes; Molecular Structure; Skin Pigmentation; Statistics as Topic | 2001 |
Cocaine, benzoylecgonine, amphetamine, and N-acetylamphetamine binding to melanin subtypes.
Topics: Amphetamine; Amphetamines; Central Nervous System Stimulants; Chromatography, Liquid; Cocaine; Hair; Hair Color; Indoles; Mass Spectrometry; Melanins | 2003 |
Involvement of photooxidation of melanogenic precursors in prolonged pigmentation induced by ultraviolet A.
Topics: Adult; Humans; Hydrogen Peroxide; In Vitro Techniques; Indoles; Male; Melanins; Oxidants; Photochemistry; Protein Precursors; Skin; Skin Pigmentation; Sunlight; Ultraviolet Rays | 2004 |
An oxygen transporter hemocyanin can act on the late pathway of melanin synthesis.
Topics: Animals; Enzyme Inhibitors; Hemocyanins; Hemolymph; Hydrogen-Ion Concentration; Indoles; Melanins; Monophenol Monooxygenase; Oxygen; Penaeidae; Structure-Activity Relationship | 2005 |
Fe(III)-coordination properties of neuromelanin components: 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid.
Topics: Dopamine; Humans; Hydrogen-Ion Concentration; Indoles; Iron; Melanins; Neurodegenerative Diseases; Oxygen; Parkinson Disease; Spectrum Analysis; Titrimetry | 2006 |
Dopaquinone redox exchange with dihydroxyindole and dihydroxyindole carboxylic acid.
Topics: Computer Simulation; Free Radicals; Indoles; Kinetics; Models, Chemical; Oxidation-Reduction | 2006 |
Parasite suppression of the oxidations of eumelanin precursors in Drosophila melanogaster.
Topics: Animals; Chromatography, High Pressure Liquid; Dopamine; Drosophila melanogaster; Electrochemistry; Host-Parasite Interactions; Indoles; Levodopa; Melanins; Oxidation-Reduction; Phenols; Tyrosine; Wasps | 2007 |
UV-absorption spectra of melanosomes containing varying 5,6-dihydroxyindole and 5,6-dihydroxyindole-2-carboxylic acid content.
Topics: Absorption; Animals; Cattle; Choroid; Indoles; Iris; Melanins; Melanosomes; Retinal Pigment Epithelium; Spectrophotometry, Ultraviolet | 2011 |
Neutral pH and copper ions promote eumelanogenesis after the dopachrome stage.
Topics: Biosynthetic Pathways; Copper; Humans; Hydrogen-Ion Concentration; Indolequinones; Indoles; Ions; Kinetics; Melanins | 2013 |
Effect of pH on elementary steps of dopachrome conversion from first-principles calculation.
Topics: Humans; Hydrogen; Hydrogen-Ion Concentration; Indolequinones; Indoles; Intramolecular Oxidoreductases; Kinetics; Models, Chemical; Pigmentation; Protons; Software; Solvents | 2014 |
Insect cuticular melanins are distinctly different from those of mammalian epidermal melanins.
Topics: Animals; Cysteinyldopa; Drosophila melanogaster; Humans; Indoles; Melanins; Sarcophagidae; Species Specificity | 2018 |
Raman spectroscopy quantification of eumelanin subunits in natural unaltered pigments.
Topics: Animals; Birds; Calibration; Feathers; Indoles; Melanins; Pigmentation; Reproducibility of Results; Spectrum Analysis, Raman | 2018 |
Effects of Aging on Hair Color, Melanosome Morphology, and Melanin Composition in Japanese Females.
Topics: Adolescent; Adult; Aged; Aging; Child; Child, Preschool; Female; Hair; Hair Color; Humans; Indoles; Melanins; Melanosomes; Middle Aged; Organelle Size; Pyrroles | 2019 |