5,6-dihydroxy-1-(2-imidazolinyl)tetralin has been researched along with clonidine in 1 studies
*Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION. [MeSH]
*Clonidine: An imidazoline sympatholytic agent that stimulates ALPHA-2 ADRENERGIC RECEPTORS and central IMIDAZOLINE RECEPTORS. It is commonly used in the management of HYPERTENSION. [MeSH]
| Studies (5,6-dihydroxy-1-(2-imidazolinyl)tetralin) | Trials (5,6-dihydroxy-1-(2-imidazolinyl)tetralin) | Recent Studies (post-2010) (5,6-dihydroxy-1-(2-imidazolinyl)tetralin) | Studies (clonidine) | Trials (clonidine) | Recent Studies (post-2010) (clonidine) |
|---|---|---|---|---|---|
| 6 | 0 | 0 | 13,692 | 2,044 | 1,394 |
| Protein | Taxonomy | 5,6-dihydroxy-1-(2-imidazolinyl)tetralin (IC50) | clonidine (IC50) |
|---|---|---|---|
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.101 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.0353 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0115 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.0173 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.21 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 5.365 | |
| Alpha-2A adrenergic receptor | Bos taurus (cattle) | 0.002 | |
| Nischarin | Rattus norvegicus (Norway rat) | 0.3662 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arendsen, DL; Buckner, SA; DeBernardis, JF; Hancock, AA; Kerkman, DJ; Kyncl, JJ | 1 |
1 other study(ies) available for 5,6-dihydroxy-1-(2-imidazolinyl)tetralin and clonidine
| Article | Year |
|---|---|
Conformationally defined adrenergic agents. 5. Resolution, absolute configuration, and pharmacological characterization of the enantiomers of 2-(5,6-dihydroxy-1,2,3,4-tetrahydro-1-naphthyl)imidazoline: a potent agonist at alpha-adrenoceptors.
Topics: Adrenergic alpha-Agonists; Animals; Dogs; Female; Imidazoles; In Vitro Techniques; Male; Molecular Conformation; Naphthalenes; Norepinephrine; Rabbits; Rats; Rats, Inbred Strains; Stereoisomerism; Tetrahydronaphthalenes; X-Ray Diffraction | 1987 |