5,6-dihydroorotate has been researched along with fumarates in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Copeland, RA; Jiang, W; Kopcho, LM; Locke, G; Marcinkeviciene, J; Rogers, MJ | 1 |
| Björnberg, O; Jensen, KF; Jordan, DB; Palfey, BA | 1 |
| Amino, H; Kita, K; Mi-ichi, F; Takamiya, S; Takashima, E; Takeo, S | 1 |
| Annoura, T; Aoki, T; Hashimoto, M; Iizumi, K; Kita, K; Makiuchi, T; Murata, E; Nara, T; Sariego, I; Tsubouchi, A | 1 |
| Aoki, T; Harada, S; Inaoka, DK; Kita, K; Kurisu, G; Nara, T; Sakamoto, K; Shiba, T; Shimizu, H | 1 |
| Cheleski, J; Citadini, AP; da Costa Filho, AJ; Montanari, CA; Nonato, MC; Wiggers, HJ | 1 |
| Harada, S; Inaoka, DK; Kita, K | 1 |
1 review(s) available for 5,6-dihydroorotate and fumarates
| Article | Year |
|---|---|
[Development of anti-trypanosome drugs targeting nucleotides biosynthesis and red-ox regulatory pathway].
Topics: Animals; Dihydroorotate Dehydrogenase; Drug Design; Energy Metabolism; Fumarates; Nucleotides; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Oxonic Acid; Protein Conformation; Succinic Acid; Trypanocidal Agents; Trypanosoma cruzi | 2009 |
6 other study(ies) available for 5,6-dihydroorotate and fumarates
| Article | Year |
|---|---|
A second dihydroorotate dehydrogenase (Type A) of the human pathogen Enterococcus faecalis: expression, purification, and steady-state kinetic mechanism.
Topics: Amino Acid Sequence; Barbiturates; Binding Sites; Catalysis; Cloning, Molecular; Dihydroorotate Dehydrogenase; Enterococcus faecalis; Enzyme Stability; Escherichia coli; Fumarates; Humans; Kinetics; Models, Chemical; Molecular Sequence Data; Molecular Weight; Orotic Acid; Oxidation-Reduction; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Oxygen; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Thermodynamics; Titrimetry; Vitamin K | 2000 |
Dihydrooxonate is a substrate of dihydroorotate dehydrogenase (DHOD) providing evidence for involvement of cysteine and serine residues in base catalysis.
Topics: Binding Sites; Catalysis; Cysteine; Dihydroorotate Dehydrogenase; Escherichia coli; Fumarates; Lactobacillus; Mutation; Orotic Acid; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Serine; Substrate Specificity | 2001 |
Isolation of mitochondria from Plasmodium falciparum showing dihydroorotate dependent respiration.
Topics: Animals; Blotting, Western; Fumarates; Mitochondria; Orotic Acid; Oxygen; Oxygen Consumption; Plasmodium falciparum; Succinate Dehydrogenase | 2001 |
Genetic diversity and kinetic properties of Trypanosoma cruzi dihydroorotate dehydrogenase isoforms.
Topics: Animals; Base Sequence; Dihydroorotate Dehydrogenase; Fumarates; Genetic Variation; Hydrogen-Ion Concentration; Isoenzymes; Kinetics; Molecular Sequence Data; Orotic Acid; Oxidoreductases Acting on CH-CH Group Donors; Point Mutation; Polymorphism, Genetic; Recombinant Proteins; Sequence Alignment; Temperature; Trypanosoma cruzi | 2006 |
Structures of Trypanosoma cruzi dihydroorotate dehydrogenase complexed with substrates and products: atomic resolution insights into mechanisms of dihydroorotate oxidation and fumarate reduction.
Topics: Amino Acid Sequence; Animals; Cloning, Molecular; Crystallography, X-Ray; Dihydroorotate Dehydrogenase; Fumarates; Models, Molecular; Molecular Sequence Data; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protein Conformation; Sequence Homology, Amino Acid; Substrate Specificity; Trypanosoma cruzi | 2008 |
Kinetic mechanism and catalysis of Trypanosoma cruzi dihydroorotate dehydrogenase enzyme evaluated by isothermal titration calorimetry.
Topics: Biocatalysis; Calorimetry; Dihydroorotate Dehydrogenase; Dimethyl Sulfoxide; Enzyme Assays; Fumarates; Kinetics; Octoxynol; Orotic Acid; Oxidoreductases Acting on CH-CH Group Donors; Recombinant Proteins; Substrate Specificity; Thermodynamics; Trypanosoma cruzi | 2010 |