Compounds > 5,6-dihydroorotate

5,6-dihydroorotate and flavin mononucleotide

5,6-dihydroorotate has been researched along with flavin mononucleotide in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jensen, KF; Mohsen, AW; Munro, AW; Rigby, SE; Scrutton, NS1
Basran, J; Combe, JP; Hothi, P; Leys, D; Munro, AW; Rigby, SE; Scrutton, NS1
Fagan, RL; Nelson, MN; Pagano, PM; Palfey, BA1
Al-Karadaghi, S; Dahlberg, L; Dufe, VT; Fritzson, I; Khairoullina, A; Svensson, B; Walse, B; Wellmar, U1
Alves, CN; Roitberg, AE; Silva, JR1

Other Studies

5 other study(ies) available for 5,6-dihydroorotate and flavin mononucleotide

ArticleYear
Thermodynamic basis of electron transfer in dihydroorotate dehydrogenase B from Lactococcus lactis: analysis by potentiometry, EPR spectroscopy, and ENDOR spectroscopy.
    Biochemistry, 2004, Jun-01, Volume: 43, Issue:21

    Topics: Dihydroorotate Dehydrogenase; Dimerization; Electron Spin Resonance Spectroscopy; Electron Transport; Flavin Mononucleotide; Flavin-Adenine Dinucleotide; Flavins; Lactococcus lactis; NAD; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Potentiometry; Protein Subunits; Thermodynamics; Titrimetry

2004
Lys-D48 is required for charge stabilization, rapid flavin reduction, and internal electron transfer in the catalytic cycle of dihydroorotate dehydrogenase B of Lactococcus lactis.
    The Journal of biological chemistry, 2006, Jun-30, Volume: 281, Issue:26

    Topics: Catalysis; Dihydroorotate Dehydrogenase; Dimerization; Electrochemistry; Electron Transport; Flavin Mononucleotide; Flavins; Lactococcus lactis; Lysine; Mutagenesis, Site-Directed; NAD; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protein Structure, Tertiary; Tyrosine

2006
Mechanism of flavin reduction in class 2 dihydroorotate dehydrogenases.
    Biochemistry, 2006, Dec-19, Volume: 45, Issue:50

    Topics: Binding Sites; Catalysis; Dihydroorotate Dehydrogenase; Escherichia coli; Escherichia coli Proteins; Flavin Mononucleotide; Humans; Hydrogen-Ion Concentration; Models, Chemical; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Serine; Substrate Specificity

2006
The structures of human dihydroorotate dehydrogenase with and without inhibitor reveal conformational flexibility in the inhibitor and substrate binding sites.
    Biochemistry, 2008, Aug-26, Volume: 47, Issue:34

    Topics: Binding Sites; Biphenyl Compounds; Carboxylic Acids; Crystallography, X-Ray; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Flavin Mononucleotide; Humans; Naphthalenes; Orotic Acid; ortho-Aminobenzoates; Oxidoreductases Acting on CH-CH Group Donors; Protein Binding; Protein Structure, Secondary; Recombinant Proteins; Ubiquinone

2008
Insights into the mechanism of oxidation of dihydroorotate to orotate catalysed by human class 2 dihydroorotate dehydrogenase: a QM/MM free energy study.
    Physical chemistry chemical physics : PCCP, 2015, Jul-21, Volume: 17, Issue:27

    Topics: Binding Sites; Biocatalysis; Dihydroorotate Dehydrogenase; Flavin Mononucleotide; Humans; Molecular Dynamics Simulation; Orotic Acid; Oxidation-Reduction; Oxidoreductases Acting on CH-CH Group Donors; Protein Structure, Tertiary; Quantum Theory; Thermodynamics

2015